A novel CUGexp·MBNL1 inhibitor with therapeutic potential for myotonic dystrophy type 1

ACS Chemical Biology

Volumn 8, Issue 5, 2013, Pages 1037-1043

  Jahromi, Amin Haghighat ^a,b   Nguyen, Lien ^b   Fu, Yuan ^b,d   Miller, Kali A ^b   Baranger, Anne M ^b,c   Zimmerman, Steven C ^b  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EXPANDED CUG REPEAT MUSCLEBLIND LIKE 1 PROTEIN INHIBITOR; INSULIN RECEPTOR; MESSENGER RNA PRECURSOR; MUSCLEBLIND LIKE 1 PROTEIN; POLYAMINE DERIVATIVE; PROTEIN; PROTEIN INHIBITOR; RNA; UNCLASSIFIED DRUG; LIGAND; MBNL1 PROTEIN, HUMAN; POLYAMINE; RNA BINDING PROTEIN; RNA PRECURSOR;

ALTERNATIVE RNA SPLICING; ARTICLE; BINDING AFFINITY; BIOLOGICAL ACTIVITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CUG REPEAT; DNA STRUCTURE; DRUG EFFECT; DRUG SOLUBILITY; DRUG STABILITY; DRUG SYNTHESIS; DRUG TARGETING; FEMALE; HUMAN; HUMAN CELL; MYOTONIC DYSTROPHY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; TIME LAPSE IMAGING; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; GENETICS; HELA CELL LINE; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; RNA SPLICING; TRINUCLEOTIDE REPEAT;

BASE SEQUENCE; HELA CELLS; HUMANS; LIGANDS; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MYOTONIC DYSTROPHY; POLYAMINES; RECEPTOR, INSULIN; RNA PRECURSORS; RNA SPLICING; RNA-BINDING PROTEINS; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 84878073420     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb400046u     Document Type: Article

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