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Volumn 345, Issue 3, 2013, Pages 464-472

Effects of a new SGLT2 inhibitor, luseogliflozin, on diabetic nephropathy in T2DN rats

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLYCOSYLATED HEMOGLOBIN; INSULIN; LISINOPRIL; LUSEOGLIFLOZIN;

EID: 84878060305     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.113.203869     Document Type: Article
Times cited : (137)

References (27)
  • 2
    • 77953857048 scopus 로고    scopus 로고
    • Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: A randomised, double-blind, placebo-controlled trial
    • Bailey CJ, Gross JL, Pieters A, Bastien A, and List JF (2010) Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: A randomised, double-blind, placebo-controlled trial. Lancet 375:2223-2233.
    • (2010) Lancet , vol.375 , pp. 2223-2233
    • Bailey, C.J.1    Gross, J.L.2    Pieters, A.3    Bastien, A.4    List, J.F.5
  • 3
    • 0034933344 scopus 로고    scopus 로고
    • Irbesartan normalises the deficiency in glomerular nephrin expression in a model of diabetes and hypertension
    • Bonnet F, Cooper ME, Kawachi H, Allen TJ, Boner G, and Cao Z (2001) Irbesartan normalises the deficiency in glomerular nephrin expression in a model of diabetes and hypertension. Diabetologia 44:874-877.
    • (2001) Diabetologia , vol.44 , pp. 874-877
    • Bonnet, F.1    Cooper, M.E.2    Kawachi, H.3    Allen, T.J.4    Boner, G.5    Cao, Z.6
  • 4
    • 28844504752 scopus 로고    scopus 로고
    • Effect of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes: Systematic review and metaanalysis
    • Casas JP, Chua W, Loukogeorgakis S, Vallance P, Smeeth L, Hingorani AD, and MacAllister RJ (2005) Effect of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes: Systematic review and metaanalysis. Lancet 366:2026-2033.
    • (2005) Lancet , vol.366 , pp. 2026-2033
    • Casas, J.P.1    Chua, W.2    Loukogeorgakis, S.3    Vallance, P.4    Smeeth, L.5    Hingorani, A.D.6    MacAllister, R.J.7
  • 6
    • 0032724757 scopus 로고    scopus 로고
    • High glucose increases growth and collagen synthesis in cultured human tubulointerstitial cells
    • Jones SC, Saunders HJ, and Pollock CA (1999) High glucose increases growth and collagen synthesis in cultured human tubulointerstitial cells. Diabet Med 16: 932-938.
    • (1999) Diabet Med , vol.16 , pp. 932-938
    • Jones, S.C.1    Saunders, H.J.2    Pollock, C.A.3
  • 7
    • 77951143723 scopus 로고    scopus 로고
    • (1S)-1,5-anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl] -1-thio-D-glucitol (TS-071) is a potent, selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for type 2 diabetes treatment
    • Kakinuma H, Oi T, Hashimoto-Tsuchiya Y, Arai M, Kawakita Y, Fukasawa Y, Iida I, Hagima N, Takeuchi H, and Chino Y, et al. (2010) (1S)-1,5-anhydro-1-[5- (4-ethoxybenzyl)-2-methoxy-4-methylphenyl]-1-thio-D-glucitol (TS-071) is a potent, selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for type 2 diabetes treatment. J Med Chem 53:3247-3261.
    • (2010) J Med Chem , vol.53 , pp. 3247-3261
    • Kakinuma, H.1    Oi, T.2    Hashimoto-Tsuchiya, Y.3    Arai, M.4    Kawakita, Y.5    Fukasawa, Y.6    Iida, I.7    Hagima, N.8    Takeuchi, H.9    Chino, Y.10
  • 8
    • 84878104996 scopus 로고    scopus 로고
    • Renoprotective effects of SGLT2 inhibitor, Luseogliflozin, on the progression of diabetic nephropathy in T2DN rats (Abstract
    • Sept 19-22, 2012, Washington, DC. Abstract 221
    • Kojima N, Williams JM, Takahasi T, Miyata N, and Roman RJ (2012) Renoprotective effects of SGLT2 inhibitor, Luseogliflozin, on the progression of diabetic nephropathy in T2DN rats (Abstract). Abstracts of High Blood Pressure Research 2012 Scientific Sessions, Sept 19-22, 2012, Washington, DC. Abstract 221, page 91.
    • (2012) Abstracts of High Blood Pressure Research 2012 Scientific Sessions , pp. 91
    • Kojima, N.1    Williams, J.M.2    Takahasi, T.3    Miyata, N.4    Roman, R.J.5
  • 9
    • 49149087718 scopus 로고    scopus 로고
    • Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): A multicentre, randomised, double-blind, controlled trial
    • ONTARGET investigators
    • Mann JF, Schmieder RE, McQueen M, Dyal L, Schumacher H, Pogue J, Wang X, Maggioni A, Budaj A, and Chaithiraphan S, et al.; ONTARGET investigators (2008) Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): A multicentre, randomised, double-blind, controlled trial. Lancet 372:547-553.
    • (2008) Lancet , vol.372 , pp. 547-553
    • Mann, J.F.1    Schmieder, R.E.2    McQueen, M.3    Dyal, L.4    Schumacher, H.5    Pogue, J.6    Wang, X.7    Maggioni, A.8    Budaj, A.9    Chaithiraphan, S.10
  • 11
    • 70349102137 scopus 로고    scopus 로고
    • Distinct genetic regulation of progression of diabetes and renal disease in the Goto-Kakizaki rat
    • Nobrega MA, Solberg Woods LC, Fleming S, and Jacob HJ (2009) Distinct genetic regulation of progression of diabetes and renal disease in the Goto-Kakizaki rat. Physiol Genomics 39:38-46.
    • (2009) Physiol Genomics , vol.39 , pp. 38-46
    • Nobrega, M.A.1    Solberg Woods, L.C.2    Fleming, S.3    Jacob, H.J.4
  • 12
    • 0029147687 scopus 로고
    • Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: A randomized prospective 6-year study
    • Ohkubo Y, Kishikawa H, Araki E,Miyata T, Isami S,Motoyoshi S, Kojima Y, Furuyoshi N, and Shichiri M (1995) Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: A randomized prospective 6-year study. Diabetes Res Clin Pract 28: 103-117.
    • (1995) Diabetes Res Clin Pract , vol.28 , pp. 103-117
    • Ohkubo, Y.1    Kishikawa, H.2    Araki, E.3    Miyata, T.4    Isami, S.5    Motoyoshi, S.6    Kojima, Y.7    Furuyoshi, N.8    Shichiri, M.9
  • 13
    • 0030820465 scopus 로고    scopus 로고
    • Exposure of human renal proximal tubular cells to glucose leads to accumulation of type IV collagen and fibronectin by decreased degradation
    • Phillips AO, Steadman R, Morrisey K, Martin J, Eynstone L, and Williams JD (1997) Exposure of human renal proximal tubular cells to glucose leads to accumulation of type IV collagen and fibronectin by decreased degradation. Kidney Int 52:973-984.
    • (1997) Kidney Int , vol.52 , pp. 973-984
    • Phillips, A.O.1    Steadman, R.2    Morrisey, K.3    Martin, J.4    Eynstone, L.5    Williams, J.D.6
  • 14
    • 33644688031 scopus 로고    scopus 로고
    • Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes
    • Rahmoune H, Thompson PW, Ward JM, Smith CD, Hong G, and Brown J (2005) Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes. Diabetes 54:3427-3434.
    • (2005) Diabetes , vol.54 , pp. 3427-3434
    • Rahmoune, H.1    Thompson, P.W.2    Ward, J.M.3    Smith, C.D.4    Hong, G.5    Brown, J.6
  • 15
    • 33645462551 scopus 로고    scopus 로고
    • Prevention and treatment of diabetic renal disease in type 2 diabetes: The BENEDICT study
    • Remuzzi G, Macia M, and Ruggenenti P (2006) Prevention and treatment of diabetic renal disease in type 2 diabetes: The BENEDICT study. J Am Soc Nephrol 17(4, Suppl 2)S90-S97.
    • (2006) J Am Soc Nephrol , vol.17 , Issue.4 SUPPL. 2
    • Remuzzi, G.1    Macia, M.2    Ruggenenti, P.3
  • 16
    • 79953828524 scopus 로고    scopus 로고
    • Endothelin receptor A-specific stimulation of glomerular inflammation and injury in a streptozotocininduced rat model of diabetes
    • SalehMA, Boesen EI, Pollock JS, Savin VJ, and Pollock DM (2011) Endothelin receptor A-specific stimulation of glomerular inflammation and injury in a streptozotocininduced rat model of diabetes. Diabetologia 54:979-988.
    • (2011) Diabetologia , vol.54 , pp. 979-988
    • Saleh, M.A.1    Boesen, E.I.2    Pollock, J.S.3    Savin, V.J.4    Pollock, D.M.5
  • 17
    • 33746330410 scopus 로고    scopus 로고
    • Insulin resistance, hyperinsulinemia, and renal injury: Mechanisms and implications
    • Sarafidis PA and Ruilope LM (2006) Insulin resistance, hyperinsulinemia, and renal injury: Mechanisms and implications. Am J Nephrol 26:232-244.
    • (2006) Am J Nephrol , vol.26 , pp. 232-244
    • Sarafidis, P.A.1    Ruilope, L.M.2
  • 18
    • 84861536065 scopus 로고    scopus 로고
    • Tofogliflozin, a potent and highly specific sodium/glucose cotransporter 2 inhibitor, improves glycemic control in diabetic rats and mice
    • Suzuki M, Honda K, Fukazawa M, Ozawa K, Hagita H, Kawai T, Takeda M, Yata T, Kawai M, and Fukuzawa T, et al. (2012) Tofogliflozin, a potent and highly specific sodium/glucose cotransporter 2 inhibitor, improves glycemic control in diabetic rats and mice. J Pharmacol Exp Ther 341:692-701.
    • (2012) J Pharmacol Exp Ther , vol.341 , pp. 692-701
    • Suzuki, M.1    Honda, K.2    Fukazawa, M.3    Ozawa, K.4    Hagita, H.5    Kawai, T.6    Takeda, M.7    Yata, T.8    Kawai, M.9    Fukuzawa, T.10
  • 19
    • 57949111356 scopus 로고    scopus 로고
    • Enhanced expressions of sodium-glucose cotransporters in the kidneys of diabetic Zucker rats
    • Tabatabai NM, Sharma M, Blumenthal SS, and Petering DH (2009) Enhanced expressions of sodium-glucose cotransporters in the kidneys of diabetic Zucker rats. Diabetes Res Clin Pract 83:e27-e30.
    • (2009) Diabetes Res Clin Pract , vol.83
    • Tabatabai, N.M.1    Sharma, M.2    Blumenthal, S.S.3    Petering, D.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.