Initial Characterization of A Rat Model of Diabetic Nephropathy

Diabetes

Volumn 53, Issue 3, 2004, Pages 735-742

  Nobrega, Marcelo A ^a,c   Fleming, Stewart ^b   Roman, Richard J ^a   Shiozawa, Masahide ^a   Schlick, Nancy ^a   Lazar, Jozef ^a   Jacob, Howard J ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DISEASE SEVERITY; GENE LOCUS; GLOMERULOSCLEROSIS; HEREDITY; HISTOPATHOLOGY; HYALINE DEGENERATION; KIDNEY DISEASE; MALE; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN;

ANIMALS; BLOOD GLUCOSE; DIABETIC NEPHROPATHIES; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; GLUCOSE TOLERANCE TEST; KIDNEY; RATS; RATS, INBRED STRAINS; TIME FACTORS;

EID: 1442325587     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.53.3.735     Document Type: Article

References (42)

1. U.S. Renal Data System: Excerpts from the USRDS 2000 Annual Data Report: atlas of end-stage renal disease in the United States. Am J Kidney Dis 36:S1-S238, 2000
2. Parving HH, Osterby R, Ritz E: Diabetic nephropathy. In Brenner and Rector's The Kidney. 6th ed. WB Saunders Company, 2000, p. 1731-1773
3. Viberti G, Wiseman MJ, Pinto JR, Messent J: Diabetic nephropathy. In Joslin's Diabetic Nephropathy. 13th ed. Philadelphia, Lippincott Williams & Wilkins, 1994, p. 691-737
4. Viberti G: Why do we have to invoke genetic susceptibility for diabetic nephropathy? Kidney Int 55:2526-2527, 1999
5. Sullivan JL: Iron and the genetics of cardiovascular disease. Circulation 100:1260-1263, 1999
6. Orloff LA, Orloff MS, Orloff SL, Orloff MJ: Lifelong prevention of mesangial enlargement by whole pancreas transplantation in rats with diabetes mellitus. Arch Surg 134:889-897, 1999
7. Lewis J, Lewis EJ: In memory of a legendary athlete: measured successes in diabetic nephropathy. Semin Nephrol 21:124-132, 2001
8. Seaquist ER, Goetz FC, Rich S, Barbosa J: Familial clustering of diabetic kidney disease: evidence for genetic susceptibility to diabetic nephropathy. N Engl J Med 320:1161-1165, 1989
9. Freedman BI, Tuttle AB, Spray BJ: Familial predisposition to nephropathy in African-Americans with NIDDM. Am J Kidney Dis 25:710-713, 1995
10. Krolewsky AS: Genetics of diabetic nephropathy: evidence for major and minor gene effects. Kidney Int 55:1582-1596, 1999
11. Marliss EB, Nakhooda AF, Poussier P: Clinical forms and natural history of the diabetic syndrome and insulin and glucagon secretion in the BB rat. Metabolism 32 (Suppl. 1):11-17, 1983
12. Schmitz PG, O'Donnell MP, Kasiske BL, Katz SA, Keane WF: Renal injury in obese Zucker rats: glomerular hemodynamic alterations and effects of enalapril. Am J Physiol 263:F496-F502, 1992
13. Velasquez MT, Abraham AA, Kimmel PL, Farkas-Szallasi T, Michaelis OE 4th: Diabetic glomerulopathy in the SHR/N-corpulent rat: role of dietary carbohydrate in a model of NIDDM. Diabetologia 38:31-38, 1995
14. Zheng F, Striker GE, Esposito C, Lupia E, Striker LJ: Strain differences rather than hyperglycemia determine the severity of glomerulosclerosis in mice. Kidney Int 54:1999-2007, 1998
15. Portha B, Serradas P, Bailbe D, Suzuki K, Goto Y, Giroix MH: Beta-cell insensitivity to glucose in the GK rat, a spontaneously non-obese model for type II diabetes. Diabetes 40:486-491, 1991
16. Ostenson CG, Khan A, Abdel-Halim SM, Guenifi A, Suzuki K, Goto Y, Efendic S: Abnormal insulin secretion and glucose metabolism in pancreatic islets from the spontaneously diabetic GK rat. Diabetologia 36:3-8, 1993
17. Guenifi A, Abdel-Halim SM, Hoog A, Falkmer S, Ostenson CG: Preserved beta-cell density in the endocrine pancreas of young, spontaneously diabetic GK rats. Pancreas 10:148-153, 1995
18. Yagihashi S, Goto Y, Kased N: Thickening of glomerular basement membrane in spontaneously diabetic rats. Diabetologia 15:309-312, 1978
19. Phillips AO: Metabolic and renal structural changes in a nonobese, normotensive rat model of type II diabetes (Abstract). J Am Soc Nephrol 9:639A, 1998
20. Phillips AO, Baboolal K, Riley S, Gröne H, Janssen U, Steadman R, Williams J, Floege J: Association of prolonged hyperglycemia with glomerular hypertrophy and renal basement membrane thickening in the Goto-Kakizaki model of non-insulin-dependent diabetes mellitus. Am J Kidney Dis 37:400-410, 2001
21. Riley SG, Steadman R, Williams JD, Floege J, Phillips AO: Augmentation of kidney injury by basic fibroblast growth factor or platelet-derived growth factor does not induce progressive diabetic nephropathy in the Goto Kakizaki model of non-insulin-dependent diabetes. J Lab Clin Med 134:304-312, 1999
22. Jacob HJ, Brown DM, Bunker RK, Daly MJ, Dzau VJ, Goodman A, Koike G, Kren V, Kurtz T, Lernmark A, et al.: Genetic linkage map of the laboratory rat, Rattus norvegicus. Nat Genet 9:63-69, 1995
23. Bradford DM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254, 1976
24. Kessler MA, Meinitzer A, Wolfbeis OS: Albumin blue 580 fluorescence assay for albumin. Anal Biochem 248:180-182, 1997
25. Pagtalunan ME, Drachman JA, Meyer TW: Methods for estimating the volume of individual glomeruli. Kidney Int 57:2644-2649, 2000
26. Markel P, Shu P, Ebeling C, Carlson GA, Nagle DL, Smutko JS, Moore KJ: Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains. Nat Genet 17:280-284, 1997
27. Galli J, Li LS, Glaser A, Ostenson CG, Jiao H, Fakhrai-Rad H, Jacob HJ, Lander ES, Luthman H: Genetic analysis of non-insulin dependent diabetes mellitus in the GK rat. Nat Genet 12:31-37, 1996
28. Gauguier D, Froguel P, Parent V, Bernard C, Bihoreau MT, Portha B, James MR, Penicaud L, Lathrop M, Ktorza A: Chromosomal mapping of genetic loci associated with non-insulin dependent diabetes in the GK rat. Nat Genet 12:38-43, 1996
29. Galli J, Fakhrai-Rad H, Kamel A, Marcus C, Norgren S, Luthman H: Pathophysiological and genetic characterization of the major diabetes locus in GK rats. Diabetes 48:2463-2470, 1999
30. Shiozawa M, Provoost AP, vanDokkum RPE, Majewski RR, Jacob HJ: Evidence of gene-gene interactions in the genetic susceptibility to renal impairment after unilateral nephrectomy. J Am Soc Nephrol 11:2068-2078, 2000
31. Kriz W, Hosser H, Hahnel B, Simons JL, Provoost AP: Development of vascular pole-associated glomerulosclerosis in the Fawn-hooded rat. JAm Soc Nephrol 9:381-396, 1998
32. Kriz W, Hosser H, Hahnel B, Gretz N, Provoost AP: From segmental glomerulosclerosis to total nephron degeneration and interstitial fibrosis: a histopathological study in rat models and human glomerulopathies. Nephrol Dial Transplant 13:2781-2798, 1998
33. Krolewski AS, Warram JH, Christlieb AR: Hypercholesterolemia: a determinant of renal function loss and deaths in IDDM patients with nephropathy. Kidney Int 45 (Suppl. 45):S125-S131, 1994
34. Breyer JA, Bain R, Evans JK, Nahman NS Jr, Lewis EJ, Cooper M, McGill J, Berl T: Predictors of the progression of renal insufficiency in patients with insulin-dependent diabetes and overt diabetic nephropathy. Kidney Int 50:1651-1658, 1996
35. Olsen S: Identification of non-diabetic glomerular disease in renal biopsies from diabetics - a dilemma. Nephrol Dial Transplant 14:1846-1849, 1999
36. Parving HH, Osterby R, Ritz E: Diabetic nephropathy. In Brenner and Rector's The Kidney. 6th ed. WB Saunders Company, 2000, p. 1731-1773
37. Brown DM, Provoost AP, Daly MJ, Lander ES, Jacob HJ: Renal disease susceptibility and hypertension are under independent genetic control in the fawn-hooded rat. Nat Genet 12:44-51, 1996
38. Keane WF, St. Peter JV, Kasiske BL: Is the aggressive management of hyperlipidemia in nephrotic syndrome mandatory? Kidney Int 42 (Suppl. 38):S134-S138, 1992
39. O'Donnel MP, Kasiske BL, Kim Y, Schmitz PG, Keane WF: Lovastatin retards the progression of established glomerular disease in obese Zucker rats. Am J Kidney Dis 22:83-89, 1993
40. Shohat J, Boner G: Role of Lipids in the progression of renal disease in chronic renal failure: evidence from animal studies and pathogenesis. Isr J Med Sci 29:228-239, 1993
41. Kasiske BL, O'Donnell MP, Garvis WJ, Keane WF: Pharmacological treatment of hyperlipidemia reduces glomerular injury in rat 5/6-nephrectomy model of chronic renal failure. Circ Res 62:367-374, 1988
42. Parving HH: Cholesterol-lowering therapy may retard the progression of diabetic nephropathy. Diabetologia 39:367-368, 1996