High glucose increases growth and collagen synthesis in cultured human tubulointerstitial cells

Diabetic Medicine

Volumn 16, Issue 11, 1999, Pages 932-938

  Jones, S C ^a,b   Saunders, H J ^a,b   Pollock, Carol A ^a,b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b ROYAL NORTH SHORE HOSPITAL   (Australia)

Author keywords

Cell growth; Diabetic nephropathy; Extracellular matrix; Tubulointerstitium

Indexed keywords

GLUCOSE;

ARTICLE; CELL CULTURE; CELL GROWTH; CELL LEVEL; COLLAGEN SYNTHESIS; DIABETIC NEPHROPATHY; HUMAN; HUMAN CELL; KIDNEY CELL; OSMOREGULATION; PATHOGENESIS;

CELL DIVISION; CELLS, CULTURED; COLLAGEN; FIBROBLASTS; GLUCOSE; HUMANS; KIDNEY CORTEX; KIDNEY TUBULES, PROXIMAL; L-LACTATE DEHYDROGENASE;

EID: 0032724757     PISSN: 07423071     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1464-5491.1999.00174.x     Document Type: Article

References (28)

1. Matsusaka T. Angiotensin in progressive renal disease: Theory and practice. J Am Soc Nephrol 1996; 7: 2020-2043.
2. Lane PH, Steffes MW, Fioretto P, Mauer SM. Renal interstitial expansion in insulin-dependent diabetes mellitus. Kidney Int 1993; 43: 661-667.
3. Fioretto P, Mauer M, Brocco E, Velussi M, Frigato F, Muollo B et al. Patterns of renal injury in NIDDM patients with microalbuminuria. Diabetologia 1996; 39: 1569-1576.
4. Brito PL, Fiorettto P, Drummond K, Kim Y, Steffes MW, Basgen JM et al. Proximal tubular basement membrane width in insulin-dependent diabetes mellitus. Kidney Int 1998; 53: 754-761.
5. Seyer-Hansen K, Hansen J, Gunderson HJG. Renal hypertrophy in experimental diabetes. Diabetologia 1980; 18: 501-505.
6. Mauer SM, Steffes MW, Ellis EN, Sutherland DER, Brown DM, Goetz FC. Structural-functional relationships in diabetic nephropathy. J Clin Invest 1984; 74: 1143-1155.
7. Eddy AA. Molecular insights into renal interstitial fibrosis. J Am Soc Nephrol 1996; 7: 2495-2508.
8. Johnson DW, Saunders HJ, Brew BK, Ganesan A, Baxter RC, Poronnik P et al. Human renal fibroblasts modulate proximal tubule cell growth and transport via the IGF-I axis. Kidney Int 1997; 52: 1486-1496.
9. Johnson DW, Saunders HJ, Brew BK, Ganesan A, Baxter RC, Poronnik P et al. Paracrine stimulation of human renal fibroblasts by proximal tubule cells. Kidney Int 1998; 54: 747-757.
10. Phillips AO, Steadman R, Morrisey K, Martin J, Eynstone L, Williams JD. Exposure of human renal proximal tubular cells to glucose leads to accumulation of type IV collagen by decreased degredation. Kidney Int 1997; 52: 973-984.
11. Phillips AO, Steadman R, Morrisey K, Williams JD. Polarity of stimulation and secretion of transforming growth factorB1 by cultured proximal tubule cells. Am J Pathol 1995; 147: 362-374.
12. Johnson DW, Brew BK, Poronnik P, Cook DI, Gyory AZ, Field MJ et al. Transport characteristics of human proximal tubule cells in primary culture. Nephrology 1997; 3: 183-194.
13. 1 dissociates human proximal tubule cell growth and Na-H exchange activity. Kidney Int 1998; 53: 1601-1607.
14. Philips N, Bashey RI, Jimenez SA. Collagen and fibrinectin expression in cardiac fibroblasts from hypertensive rats. Cardiovasc Res 1994; 28: 1342-1347.
15. Guarda E, Myers PR, Brilla CG, Tyagi SC, Weber KT. Endothelial cell induced modulation of cardiac fibroblast collagen metabolism. Cardiovasc Res 1993; 27: 1004-1008.
16. Mogensen CE, Osterby R, Gundersen HJG. Early functional and morphological vascular renal consequences of the diabetic state. Diabetlogia 1979; 17: 71-76.
17. Bilous R. The relationship between structure and functional abnormalities in diabetic nephropathy. In Pickup J, Williams G eds. Textbook of Diabetes. Oxford: Blackwell Scientific Publications, 1991; 671-676.
18. Ceol M, Nerlich A, Baggio B, Angalani F, Sauer U, Schleicher E et al. Increased glomerular alpha (IV) collagen expression and deposition in long term diabetic rats is prevented by chronic glycosaminoglycan treatment. Lab Invest 1996; 74: 484-495.
19. Gilbert RE, Cox A, Wu LL, Allen TJ, Hulthen UL, Jerums G et al. Expression of transforming growth factor-β1 and type IV collagen in the renal tubulointerstitium in experimental diabetes. Diabetes 1998; 47: 414-422.
20. Ziyadeh FN, Snipes ER, Watanabe M, Alvarez RJ, Goldfarb S, Haverty TP. High glucose induces cell hypertrophy and stimulates collagen gene transcription in proximal tubule. Am J Physiol 1990; 259: F704-F714.
21. Rocco MV, Chen Y, Goldfarb Ziyadeh FN. Elevated glucose stimulates TGF-β gene expression and bioactivity in proximal tubule. Kidney Int 1992; 41: 107-114.
22. Nakamura T, Miller D, Ruoslahti E, Border WA. Production of extracellular matrix by glomerular epithelial cells is regulated by transforming growth factor-β1. Kidney Int 1992; 41: 1213-1221.
23. Yamamoto T, Nakamura T, Noble NA, Ruoslahti E. Transforming growth factor-β is elevated in human and experimental diabetic glomerulopathy. Proc Natl Acad Sci USA 1993; 90: 1814-1818.
24. Nakamura T, Fukui M, Ebihara I, Osada S, Nagaoka I, Tomino Y et al. mRNA epression of growth factors in glomeruli of diabetic rats. Diabetes 1993; 42: 450-455.
25. + exchangers stably expressed in a fibroblast cell line. J Biol Chem 1993; 268: 25527-25535.
26. + exchanger isoforms. Cell Physiol 1995; 37: C283-C296.
27. Davies JE, Siczkowski M, Sweeney FP, Quinn PA, Krolewski B, Krolewski AS et al. Glucose induced changes in turnover of Na/H exchanger of immortalised lymphoblasts from type-1 diabetic patients with nephropathy. Diabetes 1995; 44: 382-388.
28. Trevisan R, Viberti G. Sodium-hydogen antiporter: its possible role in the genesis of diabetic nephropathy. Nephrol Dialysis, Transplant 1997; 12: 643-645.