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Volumn 97, Issue 11, 2013, Pages 5013-5026

Metabolic fluxes in Schizosaccharomyces pombe grown on glucose and mixtures of glycerol and acetate

Author keywords

13C metabolic flux analysis; Compartmentalization; Glycerol acetate; Physiology; Redox balancing; Schizosaccharomyces pombe

Indexed keywords

CENTRAL CARBON METABOLISMS; COMPARTMENTALIZATION; MAXIMUM SPECIFIC GROWTH RATES; METABOLIC FLUX ANALYSIS; OXYGEN CONSUMPTION RATE; PENTOSE PHOSPHATE PATHWAY; SCHIZOSACCHAROMYCES POMBE; TRICARBOXYLIC ACID CYCLE;

EID: 84878017668     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-013-4718-z     Document Type: Article
Times cited : (9)

References (31)
  • 1
    • 15044342010 scopus 로고    scopus 로고
    • Metabolic-flux and network analysis in fourteen hemiascomycetous yeasts
    • 10.1016/j.femsyr.2004.09.008 1:CAS:528:DC%2BD2MXisVChu70%3D
    • Blank LM, Lehmbeck F, Sauer U (2005) Metabolic-flux and network analysis in fourteen hemiascomycetous yeasts. FEMS Yeast Res 5(6-7):545-558
    • (2005) FEMS Yeast Res , vol.5 , Issue.6-7 , pp. 545-558
    • Blank, L.M.1    Lehmbeck, F.2    Sauer, U.3
  • 2
    • 0027524880 scopus 로고
    • The role of the NAD-dependent glutamate dehydrogenase in restoring growth on glucose of a Saccharomyces cerevisiae phosphoglucose isomerase mutant
    • 10.1111/j.1432-1033.1993.tb18266.x 1:CAS:528:DyaK3sXlvF2gsb4%3D
    • Boles E, Lehnert W, Zimmermann FK (1993) The role of the NAD-dependent glutamate dehydrogenase in restoring growth on glucose of a Saccharomyces cerevisiae phosphoglucose isomerase mutant. Eur J Biochem 217(1):469-477
    • (1993) Eur J Biochem , vol.217 , Issue.1 , pp. 469-477
    • Boles, E.1    Lehnert, W.2    Zimmermann, F.K.3
  • 3
    • 0032455440 scopus 로고    scopus 로고
    • Identification and characterization of MAE1, the Saccharomyces cerevisiae structural gene encoding mitochondrial malic enzyme
    • 1:CAS:528:DyaK1cXjsVCjsLc%3D
    • Boles E, de Jong-Gubbels P, Pronk JT (1998) Identification and characterization of MAE1, the Saccharomyces cerevisiae structural gene encoding mitochondrial malic enzyme. J Bacteriol 180(11):2875-2882
    • (1998) J Bacteriol , vol.180 , Issue.11 , pp. 2875-2882
    • Boles, E.1    De Jong-Gubbels, P.2    Pronk, J.T.3
  • 4
    • 84865232198 scopus 로고    scopus 로고
    • Production of recombinant proteins by yeast cells
    • 10.1016/j.biotechadv.2011.09.011
    • Celik E, Calik P (2011) Production of recombinant proteins by yeast cells. Biotechnol Adv 30(5):1108-1118
    • (2011) Biotechnol Adv , vol.30 , Issue.5 , pp. 1108-1118
    • Celik, E.1    Calik, P.2
  • 5
    • 0028953910 scopus 로고
    • Regulation of carbon metabolism in chemostat cultures of Saccharomyces cerevisiae grown on mixtures of glucose and ethanol
    • 10.1002/yea.320110503
    • de Jong-Gubbels P, Vanrolleghem P, Heijnen S, van Dijken JP, Pronk JT (1995) Regulation of carbon metabolism in chemostat cultures of Saccharomyces cerevisiae grown on mixtures of glucose and ethanol. Yeast 11(5):407-418
    • (1995) Yeast , vol.11 , Issue.5 , pp. 407-418
    • De Jong-Gubbels, P.1    Vanrolleghem, P.2    Heijnen, S.3    Van Dijken, J.P.4    Pronk, J.T.5
  • 6
    • 0030011520 scopus 로고    scopus 로고
    • Metabolic fluxes in chemostat cultures of Schizosaccharomyces pombe grown on mixtures of glucose and ethanol
    • 10.1099/13500872-142-6-1399
    • de Jong-Gubbels P, van Dijken JP, Pronk JT (1996) Metabolic fluxes in chemostat cultures of Schizosaccharomyces pombe grown on mixtures of glucose and ethanol. Microbiology 142(Pt 6):1399-1407
    • (1996) Microbiology , vol.142 , Issue.PART 6 , pp. 1399-1407
    • De Jong-Gubbels, P.1    Van Dijken, J.P.2    Pronk, J.T.3
  • 7
    • 84857624342 scopus 로고    scopus 로고
    • Microbial utilization of crude glycerol for the production of value-added products
    • 10.1007/s10295-011-1038-0 1:CAS:528:DC%2BC38Xht1WgtLk%3D
    • Dobson R, Gray V, Rumbold K (2012) Microbial utilization of crude glycerol for the production of value-added products. J Ind Microbiol Biotechnol 39(2):217-226
    • (2012) J Ind Microbiol Biotechnol , vol.39 , Issue.2 , pp. 217-226
    • Dobson, R.1    Gray, V.2    Rumbold, K.3
  • 8
    • 84870355195 scopus 로고    scopus 로고
    • Application of adaptive DO-stat feeding control to Pichia pastoris X33 cultures expressing a single chain antibody fragment (scFv)
    • 10.1007/s00449-012-0751-z 1:CAS:528:DC%2BC38XhsFSnsrvE
    • Ferreira AR, Ataide F, von Stosch M, Dias JM, Clemente JJ, Cunha AE, Oliveira R (2012) Application of adaptive DO-stat feeding control to Pichia pastoris X33 cultures expressing a single chain antibody fragment (scFv). Bioprocess Biosyst Eng 35(9):1603-1614
    • (2012) Bioprocess Biosyst Eng , vol.35 , Issue.9 , pp. 1603-1614
    • Ferreira, A.R.1    Ataide, F.2    Von Stosch, M.3    Dias, J.M.4    Clemente, J.J.5    Cunha, A.E.6    Oliveira, R.7
  • 10
    • 0035140099 scopus 로고    scopus 로고
    • Network identification and flux quantification in the central metabolism of Saccharomyces cerevisiae under different conditions of glucose repression
    • 10.1128/JB.183.4.1441-1451.2001 1:CAS:528:DC%2BD3MXhtVGmt7w%3D
    • Gombert AK, Moreira dos Santos M, Christensen B, Nielsen J (2001) Network identification and flux quantification in the central metabolism of Saccharomyces cerevisiae under different conditions of glucose repression. J Bacteriol 183(4):1441-1451
    • (2001) J Bacteriol , vol.183 , Issue.4 , pp. 1441-1451
    • Gombert, A.K.1    Moreira Dos Santos, M.2    Christensen, B.3    Nielsen, J.4
  • 12
    • 84871716860 scopus 로고    scopus 로고
    • A system of miniaturized stirred bioreactors for parallel continuous cultivation of yeast with online measurement of dissolved oxygen and off-gas
    • doi: 10.1002/bit.24633
    • Klein T, Schneider K, Heinzle E (2012) A system of miniaturized stirred bioreactors for parallel continuous cultivation of yeast with online measurement of dissolved oxygen and off-gas. Biotechnol Bioeng. doi: 10.1002/bit.24633
    • (2012) Biotechnol Bioeng
    • Klein, T.1    Schneider, K.2    Heinzle, E.3
  • 13
    • 79960224056 scopus 로고    scopus 로고
    • Acetate-glycerol cometabolism: Cultivating Schizosaccharomyces pombe on a non-fermentable carbon source in a defined minimal medium
    • 10.1016/j.jbiosc.2011.02.014 1:CAS:528:DC%2BC3MXht1Cgt7jJ
    • Klement T, Dankmeyer L, Hommes R, van Solingen P, Buchs J (2011) Acetate-glycerol cometabolism: cultivating Schizosaccharomyces pombe on a non-fermentable carbon source in a defined minimal medium. J Biosci Bioeng 112(1):20-25
    • (2011) J Biosci Bioeng , vol.112 , Issue.1 , pp. 20-25
    • Klement, T.1    Dankmeyer, L.2    Hommes, R.3    Van Solingen, P.4    Buchs, J.5
  • 15
    • 77953081695 scopus 로고    scopus 로고
    • The gld1+ gene encoding glycerol dehydrogenase is required for glycerol metabolism in Schizosaccharomyces pombe
    • 10.1007/s00253-010-2586-3 1:CAS:528:DC%2BC3cXmtlGktbk%3D
    • Matsuzawa T, Ohashi T, Hosomi A, Tanaka N, Tohda H, Takegawa K (2010) The gld1+ gene encoding glycerol dehydrogenase is required for glycerol metabolism in Schizosaccharomyces pombe. Appl Microbiol Biotechnol 87(2):715-727
    • (2010) Appl Microbiol Biotechnol , vol.87 , Issue.2 , pp. 715-727
    • Matsuzawa, T.1    Ohashi, T.2    Hosomi, A.3    Tanaka, N.4    Tohda, H.5    Takegawa, K.6
  • 16
    • 84856688493 scopus 로고    scopus 로고
    • Snf1-like protein kinase Ssp2 regulates glucose derepression in Schizosaccharomyces pombe
    • 10.1128/EC.05268-11 1:CAS:528:DC%2BC38Xis1Ojur4%3D
    • Matsuzawa T, Fujita Y, Tohda H, Takegawa K (2012a) Snf1-like protein kinase Ssp2 regulates glucose derepression in Schizosaccharomyces pombe. Eukaryot Cell 11(2):159-167
    • (2012) Eukaryot Cell , vol.11 , Issue.2 , pp. 159-167
    • Matsuzawa, T.1    Fujita, Y.2    Tohda, H.3    Takegawa, K.4
  • 17
    • 84864673073 scopus 로고    scopus 로고
    • Promotion of glycerol utilization using ethanol and 1-propanol in Schizosaccharomyces pombe
    • 10.1007/s00253-012-3971-x 1:CAS:528:DC%2BC38XotlSksr8%3D
    • Matsuzawa T, Hara F, Tohda H, Uemura H, Takegawa K (2012b) Promotion of glycerol utilization using ethanol and 1-propanol in Schizosaccharomyces pombe. Appl Microbiol Biotechnol 95(2):441-449
    • (2012) Appl Microbiol Biotechnol , vol.95 , Issue.2 , pp. 441-449
    • Matsuzawa, T.1    Hara, F.2    Tohda, H.3    Uemura, H.4    Takegawa, K.5
  • 18
    • 6044273857 scopus 로고    scopus 로고
    • Manipulation of malic enzyme in Saccharomyces cerevisiae for increasing NADPH production capacity aerobically in different cellular compartments
    • 10.1016/j.ymben.2004.06.002 1:CAS:528:DC%2BD2cXos1KksL8%3D
    • Moreira dos Santos M, Raghevendran V, Kotter P, Olsson L, Nielsen J (2004) Manipulation of malic enzyme in Saccharomyces cerevisiae for increasing NADPH production capacity aerobically in different cellular compartments. Metab Eng 6(4):352-363
    • (2004) Metab Eng , vol.6 , Issue.4 , pp. 352-363
    • Moreira Dos Santos, M.1    Raghevendran, V.2    Kotter, P.3    Olsson, L.4    Nielsen, J.5
  • 19
    • 77249099943 scopus 로고    scopus 로고
    • Overexpression of protein disulfide isomerases enhances secretion of recombinant human transferrin in Schizosaccharomyces pombe
    • 10.1007/s00253-009-2393-x 1:CAS:528:DC%2BC3cXjvVehsrc%3D
    • Mukaiyama H, Tohda H, Takegawa K (2010) Overexpression of protein disulfide isomerases enhances secretion of recombinant human transferrin in Schizosaccharomyces pombe. Appl Microbiol Biotechnol 86(4):1135-1143
    • (2010) Appl Microbiol Biotechnol , vol.86 , Issue.4 , pp. 1135-1143
    • Mukaiyama, H.1    Tohda, H.2    Takegawa, K.3
  • 20
    • 84856708060 scopus 로고    scopus 로고
    • Production and NMR analysis of the human ibuprofen metabolite 3-hydroxyibuprofen
    • 10.1016/j.jbiotec.2011.12.016 1:CAS:528:DC%2BC38XitFalsrg%3D
    • Neunzig I, Gohring A, Dragan CA, Zapp J, Peters FT, Maurer HH, Bureik M (2012) Production and NMR analysis of the human ibuprofen metabolite 3-hydroxyibuprofen. J Biotechnol 157(3):417-420
    • (2012) J Biotechnol , vol.157 , Issue.3 , pp. 417-420
    • Neunzig, I.1    Gohring, A.2    Dragan, C.A.3    Zapp, J.4    Peters, F.T.5    Maurer, H.H.6    Bureik, M.7
  • 22
    • 0031696195 scopus 로고    scopus 로고
    • Rapid simultaneous lipid extraction and transesterification for fatty acid analyses
    • 10.1023/A:1008812904017
    • Rodriquez-Ruiz J, Belarbi EH, Sanchez JLG, Alsonso DL (1998) Rapid simultaneous lipid extraction and transesterification for fatty acid analyses. Biotechnol Tech 12(9):689-691
    • (1998) Biotechnol Tech , vol.12 , Issue.9 , pp. 689-691
    • Rodriquez-Ruiz, J.1    Belarbi, E.H.2    Sanchez, J.L.G.3    Alsonso, D.L.4
  • 24
    • 63349088525 scopus 로고    scopus 로고
    • Metabolite profiling studies in Saccharomyces cerevisiae: An assisting tool to prioritize host targets for antiviral drug screening
    • 10.1186/1475-2859-8-12
    • Schneider K, Kromer JO, Wittmann C, Alves-Rodrigues I, Meyerhans A, Diez J, Heinzle E (2009) Metabolite profiling studies in Saccharomyces cerevisiae: an assisting tool to prioritize host targets for antiviral drug screening. Microb Cell Fact 8:12
    • (2009) Microb Cell Fact , vol.8 , pp. 12
    • Schneider, K.1    Kromer, J.O.2    Wittmann, C.3    Alves-Rodrigues, I.4    Meyerhans, A.5    Diez, J.6    Heinzle, E.7
  • 25
    • 33645985164 scopus 로고    scopus 로고
    • Reoxidation of cytosolic NADPH in Kluyveromyces lactis
    • 10.1111/j.1567-1364.2005.00021.x 1:CAS:528:DC%2BD28XkslyhsrY%3D
    • Tarrio N, Becerra M, Cerdan ME, Gonzalez Siso MI (2006) Reoxidation of cytosolic NADPH in Kluyveromyces lactis. FEMS Yeast Res 6(3):371-380
    • (2006) FEMS Yeast Res , vol.6 , Issue.3 , pp. 371-380
    • Tarrio, N.1    Becerra, M.2    Cerdan, M.E.3    Gonzalez Siso, M.I.4
  • 26
    • 0024742646 scopus 로고
    • Respiratory capacities of mitochondria of Saccharomyces cerevisiae CBS 8066 and Candida utilis CBS 621 grown under glucose limitation
    • 10.1007/BF00418933
    • Van Urk H, Bruinenberg PM, Veenhuis M, Scheffers WA, Van Dijken JP (1989) Respiratory capacities of mitochondria of Saccharomyces cerevisiae CBS 8066 and Candida utilis CBS 621 grown under glucose limitation. Antonie Van Leeuwenhoek 56(3):211-220
    • (1989) Antonie Van Leeuwenhoek , vol.56 , Issue.3 , pp. 211-220
    • Van Urk, H.1    Bruinenberg, P.M.2    Veenhuis, M.3    Scheffers, W.A.4    Van Dijken, J.P.5
  • 27
    • 0037145633 scopus 로고    scopus 로고
    • Correcting mass isotopomer distributions for naturally occurring isotopes
    • 10.1002/bit.10393
    • van Winden WA, Wittmann C, Heinzle E, Heijnen JJ (2002) Correcting mass isotopomer distributions for naturally occurring isotopes. Biotechnol Bioeng 80(4):477-479
    • (2002) Biotechnol Bioeng , vol.80 , Issue.4 , pp. 477-479
    • Van Winden, W.A.1    Wittmann, C.2    Heinzle, E.3    Heijnen, J.J.4
  • 28
    • 0033586461 scopus 로고    scopus 로고
    • Mass spectrometry for metabolic flux analysis
    • 10.1002/(SICI)1097-0290(19990320)62:6<739: AID-BIT13>3.0.CO;2-E 1:CAS:528:DyaK1MXhtVensLs%3D
    • Wittmann C, Heinzle E (1999) Mass spectrometry for metabolic flux analysis. Biotechnol Bioeng 62(6):739-750
    • (1999) Biotechnol Bioeng , vol.62 , Issue.6 , pp. 739-750
    • Wittmann, C.1    Heinzle, E.2
  • 29
    • 42649132891 scopus 로고    scopus 로고
    • 13C metabolic flux analysis using systems parametrized by compactification
    • 10.1186/1752-0509-2-29
    • 13C metabolic flux analysis using systems parametrized by compactification. BMC Syst Biol 2:29
    • (2008) BMC Syst Biol , vol.2 , pp. 29
    • Yang, T.H.1    Frick, O.2    Heinzle, E.3
  • 30
    • 64249155974 scopus 로고    scopus 로고
    • Numerical bias estimation for mass spectrometric mass isotopomer analysis
    • 10.1016/j.ab.2009.03.005 1:CAS:528:DC%2BD1MXkvVWgtbc%3D
    • Yang TH, Bolten CJ, Coppi MV, Sun J, Heinzle E (2009) Numerical bias estimation for mass spectrometric mass isotopomer analysis. Anal Biochem 388(2):192-203
    • (2009) Anal Biochem , vol.388 , Issue.2 , pp. 192-203
    • Yang, T.H.1    Bolten, C.J.2    Coppi, M.V.3    Sun, J.4    Heinzle, E.5
  • 31
    • 81455143861 scopus 로고    scopus 로고
    • Synthesis of FAEEs from glycerol in engineered Saccharomyces cerevisiae using endogenously produced ethanol by heterologous expression of an unspecific bacterial acyltransferase
    • 10.1002/bit.23311 1:CAS:528:DC%2BC3MXhsVOitrzM
    • Yu KO, Jung J, Kim SW, Park CH, Han SO (2012) Synthesis of FAEEs from glycerol in engineered Saccharomyces cerevisiae using endogenously produced ethanol by heterologous expression of an unspecific bacterial acyltransferase. Biotechnol Bioeng 109(1):110-115
    • (2012) Biotechnol Bioeng , vol.109 , Issue.1 , pp. 110-115
    • Yu, K.O.1    Jung, J.2    Kim, S.W.3    Park, C.H.4    Han, S.O.5


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