Identification and characterization of MAE1, the Saccharomyces cerevisiae structural gene encoding mitochondrial malic enzyme

Journal of Bacteriology

Volumn 180, Issue 11, 1998, Pages 2875-2882

  Boles, Eckhard ^a   De Jong Gubbels, Patricia ^b   Pronk, Jack T ^b  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; FUNGAL PROTEIN; MALATE DEHYDROGENASE (DECARBOXYLATING); MALIC ACID; MITOCHONDRIAL ENZYME; PYRUVIC ACID;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME MECHANISM; FUNGAL GENETICS; FUNGUS MUTANT; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE INDUCTION; GENE ISOLATION; GENE OVEREXPRESSION; MITOCHONDRIAL RESPIRATION; NONHUMAN; PRIORITY JOURNAL; RNA ANALYSIS; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

SACCHAROMYCES CEREVISIAE;

EID: 0032455440     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.180.11.2875-2882.1998     Document Type: Article

References (38)

1. Allison, D. S., and G. Schatz. 1986. Artificial mitochondrial presequences. Proc. Natl. Acad. Sci. USA 83:9011-9015.
2. Boles, E. 1997. Pyruvate kinase, p. 171-186. In K.-D. Entian and F. K. Zimmermann (ed.), Yeast sugar metabolism: biochemistry, genetics, biotechnology and applications. Technomic Publishing Co., Lancaster, Pa.
3. Boles, E. Unpublished data.
4. Boles, E., F. Schulte, T. Miosga, K. Freidel, E. Schlüter, F. K. Zimmermann, C. P. Hollenberg, and J. J. Heinisch. 1997. Characterization of a glucose-repressed pyruvate kinase (Pyk2p) in Saccharomyces cerevisiae that is catalytically insensitive to fructose-1,6-bisphosphate. J. Bacteriol. 179:2987-2993.
5. Bornaes, C., J. G. Petersen, and S. Holmberg. 1992. Serine and threonine catabolism in Saccharomyces cerevisiae: the CHA1 polypeptide is homologous with other serine and threonine dehydratases. Genetics 131:531-539.
6. Bornaes, C., M. W. Ignjatovic, P. Schjerling, M. C. Kielland-Brandt, and S. A. Holmberg. 1993. A regulatory element in the CHA1 promoter which confers inducibility by serine and threonine on Saccharomyces cerevisiae genes. Mol. Cell. Biol. 13:7604-7611.
7. Bruinenberg, P. M., J. P. van Dijken, J. G. Kuenen, and W. A. Scheffers. 1985. Oxidation of NADH and NADPH by mitochondria from the yeast Candida utilis. J. Gen. Microbiol. 131:1043-1051.
8. Burke, R. L., P. Tekamp-Olson, and R. Najarian. 1983. The isolation, characterizalion, and sequence of the pyruvate kinase gene of Saccharomyces cerevisiae. J. Biol. Chem. 258:2193-2201.
9. DeRisi, J. L., V. R. Iyer, and P. O. Brown. 1997. Exploring the metabolic and genetic control of gene expression on a genomic scale. Science 278:680-686.
10. Distel, B., I. van der Leij, and W. Kos. 1996. Peroxisome isolation, p. 133-138. In I. Evans (ed.) Methods in molecular biology. Humana Press, Totowa, N.J.
11. Dohmen, R. J., A. W. M. Strasser, C. B. Höner, and C. P. Hollenberg. 1991. An efficient transformation procedure enabling long-term storage of competent cells of various yeast genera. Yeast 7:691-692.
12. Douma, A. C., M. Veenhuis, W. de Koning, M. Evers, and W. Harder. 1985. Dihydroxyacetone synthase is localized in the peroxisomal matrix of methanol-grown Hansenula polymorpha. Arch. Microbiol. 143:237-243.
13. Fernández, M. J., L. Medrano, M. Ruiz-Amil, and M. Losada. 1967. Regulation and function of pyruvate kinase and malate enzyme in yeast. Eur. J. Biochem. 3:11-18.
14. Fuck, E., G. Stärk, and F. Radler. 1973. Äpfelsäurestofiwechsel bei Saccharomyces. II. Anreicherung und Eigenschaften eines Malatenzyms. Arch. Mikrobiol. 89:223-231.
15. Güldener, U., S. Heck, T. Fiedler, J. Beinhauer, and J. H. Hegemann. 1996. A new efficient gene disruption cassette for repeated use in budding yeast. Nucleic Acids Res. 24:2519-2524.
16. Kuczynski, J. T., and F. Radler. 1982. The anaerobic metabolism of malate of Saccharomyces bailii and the partial purification of malic enzyme. Arch. Microbiol. 131:266-270.
17. McNally, T., I. J. Purvis, L. A. Fothergill-Gilmore, and A. J. P. Brown. 1989. The yeast pyruvate kinase gene does not contain a string of non-preferred codons: revised nucleotide sequence. FEBS Lett. 247:312-316.
18. Miller, J. H. 1972. Experiments in molecular genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
19. Mumberg, D., R. Müller, and M. Funk. 1994. Regulatable promoters of Saccharomyces cerevisiae: comparison of transcriptional activity and their use for heterologous expression. Nucleic Acids Res. 22:5767-5788.
20. Polakis, E. S., and W. Hartley. 1965. Changes in the enzyme activities of Saccharomyces cerevisiae during aerobic growth on different carbon sources. Biochem. J. 97:284-297.
21. Postma, E., C. Verdujn, W. A. Scheffers, and J. P. van Dijken. 1989. Enzymic analysis of the Crabtree effect in glucose-limited chemostat cultures of Saccharomyces cerevisiae. Appl. Environ. Microbiol. 53:468-477.
22. Pronk, J. T., H. Y. Steensma, and J. P. van Dijken. 1996. Pyruvate metabolism in Saccharomyces cerevisiae. Yeast 12:1607-1633.
23. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
24. Schmitt, M. E., T. A. Brown, and B. L. Trumpower. 1990. A rapid and simple method for preparation of RNA from Saccharomyces cerevisiae. Nucleic Acids Res. 18:3091-3092.
25. Schomburg, D., and D. Stephan. 1995. Enzyme handbook, vol. 9. Class 1.1 oxidoreductases EC 1.1.1.1-EC 1.1.1.149. Springer Verlag, Berlin, Germany.
26. Sherman, F. 1990. Guide to yeast genetics and molecular biology. Getting started with yeast. Methods Enzymol. 194:3-20.
27. Stucka, R., S. Dequin, J. M. Salmon, and C. Gancedo. 1991. DNA sequences in chromosomes II and VII code for pyruvate carboxylase isoenzymes in Saccharomyces cerevisiae: analysis of pyruvate carboxylase-deficient strains. Mol. Gen. Genet. 229:307-315.
28. Temperli, A., U. Künsch, K. Mayer, and I. Busch. 1965. Reinigung und Eigenschaften der Malatdehydrogenase (decarboxylierend) aus Hefe. Biochim. Biophys. Acta 110:630-632.
29. Umbarger, H. E. 1978. Amino acid biosynthesis and its regulation. Annu. Rev. Biochem. 47:533-606.
30. Verduyn, C., E. Postma, W. A. Scheffers, and J. P. van Dijken. 1990. Physiology of Saccharomyces cerevisiae in anaerobic glucose-limited chemostat cultures. J. Gen. Microbiol. 136:395-403.
31. Verduyn, C., E. Postma, W. A. Scheffers, and J. P. van Dijken. 1992. Effect of benzoic acid on metabolic fluxes in yeast: a continuous-culture study on the regulation of respiration and fermentation. Yeast 8:501-517.
32. Viljoen, M., R. E. Subden, A. Krizus, and H. J. J. van Vuuren. 1994. Molecular analysis of the malic enzyme gene (mae2) of Schizosaccharomyces pombe. Yeast 10:613-624.
33. Volschenk, H., M. Viljoen, J. Grobler, B. Petzold, F. Bauer, R. E. Subden, R. A. Young, A. Lonvaud, M. Denayrolles, and H. J. J. van Vuuren. 1997. Engineering pathways for malate degradation in Saccharomyces cerevisiae. Nat. Biotechnol. 15:253-257.
34. van Dijken, J. P., and W. A. Scheffers. 1986. Redox balances in the metabolism of sugars by yeasts. FEMS Microbiol. Rev. 32:199-224.
35. von Heijne, G. 1986. Mitochondrial targeting sequences may form amphiphilic helices. EMBO J. 5:1335-1342.
36. Wach, A., A. Brachat, R. Pohlmann, and P. Philippsen. 1994. New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae. Yeast 10:1793-1808.
37. Wingender, E., A. E. Kel, O. V. Kel, H. Karas, T. Heinemejer, P. Dietze, R. Knüppel, A. G. Romaschenko, and N. A. Kolchanov. 1997. TRANSFAC, TRRD and COMPEL: towards a federated database system on transcriptional regulation. Nucleic Acids Res. 25:265-268.
38. Zinser, E., and G. Daum. 1995. Isolation and biochemical characterization of organelles from the yeast, Saccharomyces cerevisiae. Yeast 11:493-536.