Expression of metastasis-related genes in surgical specimens of human gastric cancer can predict disease recurrence

European Journal of Cancer

Volumn 34, Issue 4, 1998, Pages 558-565

  Anzai, H ^a   Kitadai, Y ^b   Bucana, C D ^b   Sanchez, R ^b   Omoto, R ^a   Fidler, I J ^b  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Gene expression; In situ hybridisation; Metastasis; Molecular diagnosis

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; EPIDERMAL GROWTH FACTOR; GELATINASE A; MULTIDRUG RESISTANCE PROTEIN; UVOMORULIN;

ARTICLE; CANCER GRADING; CANCER RECURRENCE; CANCER STAGING; DISEASE MARKER; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IN SITU HYBRIDIZATION; METASTASIS; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; STOMACH CANCER;

CADHERINS; COLLAGENASES; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION; GENES, MDR; HUMANS; IN SITU HYBRIDIZATION; MATRIX METALLOPROTEINASE 9; NEOPLASM RECURRENCE, LOCAL; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA, MESSENGER; RNA, NEOPLASM; STOMACH NEOPLASMS;

EID: 0032033804     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(97)10075-2     Document Type: Article

References (73)

1. Behrs OH, Meyers MH, eds. Manual for Staging of Cancer. Philadelphia, JB Lippincott, 1983.
2. Kakeji Y, Tujitani S, Baba H, et al. Clinicopathological features and prognostic significance of duodenal invasion in patients with distal gastric carcinoma. Cancer 1991, 68, 380-384.
3. Digiorgio A, Botti C, Sammartino P, Mingazzini P, Flammia M, Stipa V. Extracapsular lymph node metastases in the staging and prognosis of gastric cancer. Int Surg 1991, 76, 218-221.
4. Secco GB, Fardelli R, Campora E, Rovida S, Lapertosa G, Motta G. Grading as a prognostic factor: review of 209 primary gastric cancers. Tumorigenicity 1989, 75, 494-497.
5. Steinberg SM, Barwick KW, Stablein DM. Importance of tumor pathology and morphology in patients with surgically resected colon cancer. Cancer 1986, 58, 1340-1345.
6. Fidler IJ. Critical factors in the biology of human cancer metastasis: twenty-eighth GHA Clowes Memorial Award Lecture. Cancer Res 1990, 50, 6130-6138.
7. Fidler IJ. Orthotopic implantation of human colon carcinomas into nude mice provides a valuable model for the biology and therapy of cancer metastasis. Cancer Metastasis Rev 1991, 10, 229-243.
8. Fidler IJ. Modulation of the organ microenvironment for the treatment of cancer metastasis (commentary). J Nad Cancer Inst 1995,87, 1588-1592.
9. Aukerman SL, Price JE, Fidler IJ. Different deficiencies in the prevention of tumorigenic-low-metastatic murine K-1735 melanoma cells from producing metastases. J Natl Cancer Inst 1986, 77,915-924.
10. Radinsky R. Paracrine growth regulation of human colon carcinoma organ-specific metastasis. Cancer Metastasis Rev 1993, 12, 345-361.
11. Markowitz SD, Molkentin K, Gerbic C, Jackson J, Stellato T, Willson JKV. Growth stimulation by coexpression of transforming growth factor-a and epidermal growth factor receptor in normal and adenomatous human colon epithelium. J Clin Invest 1990,86, 356-362.
12. Gross ME, Zorbas MA, Daniels YJ, et al. Cellular growth response to epidermal growth factor in colon carcinoma cells with an amplified epidermal growth factor receptor derived from a familial adenomatous polyposis patient. Cancer Res 1991, 51, 1452-1459.
13. Tokunaga A, Onda M, Okuda T, et al. Clinical significance of epidermal growth factor, EGF-receptor, and c-erbB-2 in human gastric cancer. Cancer 1994, 75, 1418-1424.
14. Karameris A, Kanavaros P, Aninos D, et al. Expression of epidermal growth factor and epidermal growth factor-receptor in gastric and colorectal carcinomas. Path Res Pract 1993, 189, 133137.
15. Bradly SJ, Garfinkle G, Walker E, Salem R, Chen LB, Steele G. Increased expression of the epidermal growth factor receptor on human colon carcinoma cells. Arch Surg 1986, 121, 1242-1247.
16. Mendelsohn J. The epidermal growth factor receptor as a target for therapy with antireceptor monoclonal antibodies. Semin Cancer Biol 1990, 1, 339-344.
17. Radinsky R, Risin S, Fan D, et al. Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells. Clin Cancer Res 1995, 1, 19-31.
18. Lee EY, Cibull ML, Strodel WE, Haley JV. Expression of HER2/neu oncoprotein and epidermal growth factor receptor and prognosis in gastric carcinoma. Arch Pathol Lab Med 1994, 118, 235-239.
19. Singh RK, Bucana CD, Gutman M, Fan D, Wilson MR, Fidler IJ. The influence of the organ microenvironment on the expression of basic fibroblast growth factor in human renal cell carcinoma cells. Am J Pathol 1994, 145, 365-374.
20. Folkman MJ. The role of angiogenesis in tumor growth. Semin Cancer Biol 1992, 3, 65-71.
21. Grigioni WF, D'Errico A, Fortunato C, et al. Prognosis of gastric carcinoma revealed by interactions between tumor cells and basement membrane. Modem Pathol 1994, 7, 220-225.
22. D'Errico A, Garbisa S, Liotta LA, Castronovo V, Stetler-Stevenson WG, Grigioni WF. Augmentation of type IV collagenase, laminin receptor, and Ki67 proliferation antigen associated with human colon, gastric, and breast carcinoma progression. Modern Pathol 1991,4, 239-246.
23. Liotta LA, Steeg PS, Stetler-Stevenson WG. Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell 1991,64, 327-336.
24. Levy AT, Cioce V, Sobel ME, et al. Increased expression of the Mr 72,000 type IV collagenase in human colonie adenocarcinoma. Cancer Res 1991, 51, 439-444.
25. Poulsom R, Pignatelli M, Stetler-Stevenson WG, et al. Stromal expression of 72-kDa type IV collagenase (MMP-2) and TIMP2 mRNAs in colorectal neoplasia. Am J Pathol 1992,141, 389-396.
26. Tryggvason K, Hoyhtya M, Pyke C. Type IV collagenase in invasive tumors. Breast Cancer Res Treat 1993, 24, 209-218.
27. Fujii H, Tanigawa N, Muraoka R, Shimomatsuya T, Tanaka T. Clinical significance of multidrug resistance and P-glycoprotein expression in patients with gastric carcinoma. J Surg Oncol 1995, 58, 63-69.
28. Wallner J, Depisch D, Gsur AM, Götzl M, Haider K, Pirker R. MDR-1 gene expression and its clinical relevance in primary gastric carcinomas. Cancer 1992, 71, 667-671.
29. Baldini N. Multidrug resistance-a multiplex phenomenon. Nature Med 1997, 3, 378-380.
30. Bargou RC, Jurchott K, Wagener G, et al. Nuclear localization and increased levels of transcription factor YB-1 in primary human breast cancers are associated with intrinsic MDR1 gene expression. Nature Med 1997, 3, 447-450.
31. Weinstein RS, Jakate SM, Dominguez JM, et al. Relationship of the expression of the multidrug resistance gene product (P-glycoprotein) in human colon carcinoma to local tumor aggressiveness and lymph node metastasis. Cancer Res 1991, 51, 27202726.
32. Mayer B, Johnson JP, Leitl F, et al. E-Cadherin expression in primary and metastatic gastric cancer: downregulation correlates with cellular dedifferentiation and glandular disintegration. Cancer Res 1993, 53, 1690-1695.
33. Oka H, Shiozaki H, Kobayashi H, et al. Immunohistochemical evaluation of E-cadherin adhesion molecule expression in human gastric cancer. Virchows Arch A Pathol Anat 1992, 421, 139-156.
34. Dorudi S, Sheffield JP, Poulsom R, Northover JMA, Hart IR. Ecadherin expression in colorectal cancer. An immunocytochemical and in situ hybridization study. Am J Pathol 1993, 142, 1-986.
35. Bohm M, Totzeck B, Birchmeier W, Wieland I. Differences of E-cadherin expression levels and patterns in primary and metastatic human lung cancer. Clin Exp Metastasis 1994, 12, 55-62.
36. Frixen UH, Behrens J, Sachs M, et al. E-cadherin-mediated cellcell adhesion prevents invasiveness of human carcinoma cells. J CellBiol 1991, 113, 173-185.
37. Shimoyama Y, Hirohashi S, Hirano S, et al. Cadherin cell adhesion molecules in human epithelial tissues and carcinomas. Cancer Res 1989, 49, 2128-2133.
38. Fidler IJ, Radinsky R. Genetic control of cancer metastasis (editorial). J Natl Cancer Inst 1990, 82, 166-168.
39. Bucana CD, Radinsky R, Dong Z, Sanchez R, Brigati DJ, Fidler IJ. A rapid colorimetric in situ mRNA hybridization technique using hyperbiotinylated oligonucleotide probes for analysis of mdr-l in mouse colon carcinoma cells. J Histochem Cytochem 1993,41, 499-506.
40. Radinsky R, Bucana CD, Ellis LM, et al. A rapid colorimetric in situ messenger RNA hybridization technique for analysis of epidermal growth factor receptor in paraffin-embedded surgical specimens of human colon carcinomas. Cancer Res 1993, 53, 937-943.
41. Kitadai Y, Bucana CD, Ellis LM, Anzai H, Tahara E, Fidler IJ. In situ mRNA hybridization technique for analysis of metastasisrelated genes in human colon carcinoma cells. Am J Pathol 1995, 147, 1238-1247.
42. Kitadai Y, Ellis LM, Takahashi Y, et al. Multiparametric in situ mRNA hybridization analysis to detect metastasis-related genes in surgical specimens of human colon carcinomas. Clin Cancer Res 1995, 1, 1095-1102.
43. Kitadai Y, Ellis LM, Tucker SL, et al. Multiparametric in situ mRNA hybridization analysis to predict disease recurrence in patients with colon carcinoma. Am J Pathol 1996,149, 1541-1551.
44. Ullrich A, Coussens L, Hayflick JS, et al. Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature 1984,309,418-428.
45. Rogelj S, Weinberg RA, Fanning P, Klagsbrun M. Basic fibroblast growth factor fused to a signal peptide transforms cells. Nature 1988,331, 173-175.
46. Collier IE, Wilhelm SM, Eisen AZ, et al. H-ras oncogene-transformed human bronchial epithelial cells (TBE-1 ) secrete a single metalloprotease capable of degrading basement membrane collagen. J Biol Chem 1988, 263, 6579-6587.
47. Bussemakers MJG, Bokhoven A van, Mees SGM, Kemler R, Schalken JA. Molecular cloning and characterization of the human E-cadherin cDNA. Mol Biol Reports 1993, 17, 123-128.
48. Galski H, Sullivan M, Willingham MC, et al. Expression of a human multidrug resistance cDNA (mdr-1 ) in the bone marrow of transgenic mice: resistance to daunomycin-induced leukopenia. Mol Cell Biol 1989, 9, 4357-4363.
49. Pearson WR, Lipman DJ. Improved tools for biological sequence comparison. Proc Natl Acad Sei USA 1988, 85, 2444-2448.
50. Canadiers MH, Beaucage SL, Efcavitch JW, et al. Chemical synthesis and biological studies on mutated gene-control regions. Cold Spring Harbor Symp Quant Biol 1982, 47, 411-418.
51. Reed JA, Manahan LJ, Park CS, Brigati DJ. Complete one-hour immunocytochemistry based on capillary action. Biotechniques 1992, 13,434-443.
52. Park CS, Brigati DJ, Manahan LJ. Automated molecular pathology: one hour in situ DNA hybridization. J Histotechnol 1991, 14, 219-229.
53. Sollberg HE. Discrimiant analysis. Crit Rev Clin Lab Sei 1978, 9, 212-213.
54. Statistical Analysis Systems. SAS/STAT User's Guide. Gary, NC, SAS Institute, 1990, 677-771.
55. Anzai H, Kitadai Y, Bucana CD, Sanchez R, Omoto R, Fidler IJ. Intratumoral heterogeneity and inverse correlation between expression of E-cadherin and collagenase type IV in human gastric carcinomas. Differentiation 1996,60, 119-127.
56. Price JE, Aukerman SL, Fidler IJ. Evidence that the process of murine melanoma metastasis is sequential and selective and contains stochastic elements. Cancer Res 1986, 46, 5172-5178.
57. Morikawa K, Walker SM, Jessup JM, Fidler IJ. In vivo selection of highly metastatic cells from surgical specimens of different human colon carcinomas implanted into nude mice. Cancer Res 1988,48, 1943-1948.
58. Fidler IJ, Kripke ML. Metastasis results from preexisting variant cells within a malignant tumor. Science 1977, 197, 893-895.
59. Xie B, Bucana CD, Fidler IJ. Density-dependent induction of 92-kD type IV collagenase activity in cultures of A431 human epidermoid carcinoma cells. Am}Pathol 1994, 144, 1058-1067.
60. Takeichi M. Cadherins: a molecular family important in selective cell-cell adhesion. Annu Rev Biochem 1990, 59, 237-252.
61. Takeichi M. Cadherin cell adhesion receptors as a morphogenetic regulator. Science 1991, 251, 1451-1455.
62. Brabant G, Hoang-Yu C, Cetin Y, et al. E-cadherin: a differentiation marker in thyroid malignancies. Cancer Res 1993, 53, 4987-4993.
63. Kadowaki T, Shiozaki H, Inoue M, et al. E-cadherin and acatenin expression in human esophageal cancer. Cancer Res 1994,54,291-296.
64. Schipper JH, Frixen UH, Behrens J, Unger A, Jahnke K, Birchmeier W. E-cadherin expression in squamous carcinomas of the head and neck: inverse correlation with tumor dedifferentiation and lymph node metastasis. Cancer Res 1991, 51, 6328-6337.
65. Shimoyama Y, Hirohashi S. Expression of E- and P-cadherin in gastric carcinomas. Cancer Res 1991, 51, 2185-2192.
66. Umbas R, Schalken JA, Alders TW, et al. Expression of the cellular adhesion molecule E-cadherin is reduced or absent in highgrade prostate cancer. Cancer Res 1992, 52, 5104-5109.
67. Vleminckx K, Vakaet L Jr, Mareel M, Fiers W, Van Roy F. Genetic manipulation of E-cadherin expression by epithelial tumor cell reveals an invasion suppressor role. Cell 1991, 66, 107-119.
68. Birchmeier W. E-cadherin as a tumor (invasion) suppressor gene. BioEssays 1995, 17, 97-99.
69. D'Errico A, Garbisa S, Liotta LA, Castronovo V, Stetler-Stevenson WG, Grigioni WF. Augmentation of type IV collagenase, laminin receptor, and Ki67 proliferation antigen associated with human colon, gastric, and breast carcinoma progression. Modern Pathol 1991,4, 239-246.
70. Matrisian LM, Bowden GT. Stromelysin/transin and tumor progression. Semin Cancer Biol 1990, 1, 107-115.
71. Murphy G, Docherty AJP. The matrix metalloproteinases and their inhibitors. Am J Respir Cell Mol Biol 1992,7, 120-125.
72. Albini A, Melchiori A, Santi L, Liotta LA, Brown PD, StetlerStevenson WG. Tumour cell invasion inhibited by TIMP-2. J Nad Cancer Inst 1991, 83, 775-779.
73. DeClerck YA, Yean T-D, Chan D, Shimada H, Langley KE. Inhibition of tumor invasion of smooth muscle cell layers by recombinant human metalloproteinase inhibitor. Cancer Res 1991,51,2151-2157.