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Volumn 99, Issue 1, 2013, Pages 6-11

Development of a multiplex phenotypic cell-based high throughput screening assay to identify novel hepatitis C virus antivirals

Author keywords

HCV; High throughput Screening assay; Multiplex; Phenotypic

Indexed keywords

2' METHYLCYTIDINE; A 837093; ANTIVIRUS AGENT; GREEN FLUORESCENT PROTEIN; N2 [2 (3,5 DIFLUOROPHENYL) 2 HYDROXYACETYL] N1 (6,7 DIHYDRO 5 METHYL 6 OXO 5H DIBENZ[B,D]AZEPIN 7 YL)ALANINAMIDE; NONSTRUCTURAL PROTEIN 5B; PROTEINASE INHIBITOR; RED FLUORESCENT PROTEIN; SOFOSBUVIR; TELAPREVIR; UNCLASSIFIED DRUG;

EID: 84878007520     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2013.04.020     Document Type: Article
Times cited : (14)

References (29)
  • 1
    • 47049112231 scopus 로고    scopus 로고
    • Combinations of 2'-Cmethylcytidine analogues with interferon-alpha2b and triple combination with ribavirin in the hepatitis C virus replicon system
    • Bassit, L., Grier, J., Bennett, M., Schinazi, R.F., 2008. Combinations of 20-Cmethylcytidine analogues with interferon-alpha2b and triple combination with ribavirin in the hepatitis C virus replicon system. Antivir. Chem. Chemother. 19, 25-31.
    • (2008) Antivir. Chem. Chemother. , vol.19 , pp. 25-31
    • Bassit, L.1    Grier, J.2    Bennett, M.3    Schinazi, R.F.4
  • 2
    • 35649014170 scopus 로고    scopus 로고
    • Interferon-based therapy of hepatitis C
    • Chevaliez, S., Pawlotsky, J.M., 2007. Interferon-based therapy of hepatitis C. Adv. Drug Deliv. Rev. 59, 1222-1241.
    • (2007) Adv. Drug Deliv. Rev. , vol.59 , pp. 1222-1241
    • Chevaliez, S.1    Pawlotsky, J.M.2
  • 3
    • 77649247824 scopus 로고    scopus 로고
    • A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle
    • Chockalingam, K., Simeon, R.L., Rice, C.M., Chen, Z., 2010. A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle. Proc. Natl. Acad. Sci. USA 107, 3764-3769.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 3764-3769
    • Chockalingam, K.1    Simeon, R.L.2    Rice, C.M.3    Chen, Z.4
  • 4
    • 76249126162 scopus 로고    scopus 로고
    • Unbiased probing of the entire hepatitis C virus life cycle identifies clinical compounds that target multiple aspects of the infection
    • Gastaminza, P., Whitten-Bauer, C., Chisari, F.V., 2010. Unbiased probing of the entire hepatitis C virus life cycle identifies clinical compounds that target multiple aspects of the infection. Proc. Natl. Acad. Sci. USA 107, 291-296.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 291-296
    • Gastaminza, P.1    Whitten-Bauer, C.2    Chisari, F.V.3
  • 5
    • 78751634447 scopus 로고    scopus 로고
    • Hepatitis C virus complete life cycle screen for identification of small molecules with pro- or antiviral activity
    • Gentzsch, J., Hinkelmann, B., Kaderali, L., Irschik, H., Jansen, R., Sasse, F., Frank, R., Pietschmann, T., 2011. Hepatitis C virus complete life cycle screen for identification of small molecules with pro- or antiviral activity. Antiviral Res. 89, 136-148.
    • (2011) Antiviral Res. , vol.89 , pp. 136-148
    • Gentzsch, J.1    Hinkelmann, B.2    Kaderali, L.3    Irschik, H.4    Jansen, R.5    Sasse, F.6    Frank, R.7    Pietschmann, T.8
  • 6
    • 80053339008 scopus 로고    scopus 로고
    • An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver Diseases
    • American Association for Study of Liver, D
    • Ghany, M.G., Nelson, D.R., Strader, D.B., Thomas, D.L., Seeff, L.B., American Association for Study of Liver, D., 2011. An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver Diseases. Hepatology 54, 1433-1444.
    • (2011) Hepatology , vol.54 , pp. 1433-1444
    • Ghany, M.G.1    Nelson, D.R.2    Strader, D.B.3    Thomas, D.L.4    Seeff, L.B.5
  • 7
    • 33644547392 scopus 로고    scopus 로고
    • Antiviral therapy for chronic hepatitis C: past, present, and future
    • Hayashi, N., Takehara, T., 2006. Antiviral therapy for chronic hepatitis C: past, present, and future. J. Gastroenterol. 41, 17-27.
    • (2006) J. Gastroenterol. , vol.41 , pp. 17-27
    • Hayashi, N.1    Takehara, T.2
  • 10
    • 84870372937 scopus 로고    scopus 로고
    • Highly efficient full-length hepatitis C virus genotype 1 (strain TN) infectious culture system
    • Li, Y.P., Ramirez, S., Jensen, S.B., Purcell, R.H., Gottwein, J.M., Bukh, J., 2012. Highly efficient full-length hepatitis C virus genotype 1 (strain TN) infectious culture system. Proc. Natl. Acad. Sci. USA 109, 19757-19762.
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 19757-19762
    • Li, Y.P.1    Ramirez, S.2    Jensen, S.B.3    Purcell, R.H.4    Gottwein, J.M.5    Bukh, J.6
  • 11
    • 33646446894 scopus 로고    scopus 로고
    • VX-950, a novel hepatitis C virus (HCV) NS3-4A protease inhibitor, exhibits potent antiviral activities in HCv replicon cells
    • Lin, K., Perni, R.B., Kwong, A.D., Lin, C., 2006. VX-950, a novel hepatitis C virus (HCV) NS3-4A protease inhibitor, exhibits potent antiviral activities in HCv replicon cells. Antimicrob. Agents Chemother. 50, 1813-1822.
    • (2006) Antimicrob. Agents Chemother. , vol.50 , pp. 1813-1822
    • Lin, K.1    Perni, R.B.2    Kwong, A.D.3    Lin, C.4
  • 17
    • 33747797031 scopus 로고    scopus 로고
    • Treating viral hepatitis C: efficacy, side effects, and complications
    • Manns, M.P., Wedemeyer, H., Cornberg, M., 2006. Treating viral hepatitis C: efficacy, side effects, and complications. Gut 55, 1350-1359.
    • (2006) Gut , vol.55 , pp. 1350-1359
    • Manns, M.P.1    Wedemeyer, H.2    Cornberg, M.3
  • 18
    • 62049083697 scopus 로고    scopus 로고
    • Development of a cell-based assay for high-throughput screening of inhibitors against HCV genotypes 1a and 1b in a single well
    • Mondal, R., Koev, G., Pilot-Matias, T., He, Y., Ng, T., Kati, W., Molla, A., 2009. Development of a cell-based assay for high-throughput screening of inhibitors against HCV genotypes 1a and 1b in a single well. Antiviral Res. 82, 82-88.
    • (2009) Antiviral Res. , vol.82 , pp. 82-88
    • Mondal, R.1    Koev, G.2    Pilot-Matias, T.3    He, Y.4    Ng, T.5    Kati, W.6    Molla, A.7
  • 19
    • 3142764760 scopus 로고    scopus 로고
    • Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes
    • Moradpour, D., Evans, M.J., Gosert, R., Yuan, Z., Blum, H.E., Goff, S.P., Lindenbach, B.D., Rice, C.M., 2004. Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes. J. Virol. 78, 7400-7409.
    • (2004) J. Virol. , vol.78 , pp. 7400-7409
    • Moradpour, D.1    Evans, M.J.2    Gosert, R.3    Yuan, Z.4    Blum, H.E.5    Goff, S.P.6    Lindenbach, B.D.7    Rice, C.M.8
  • 22
    • 34547697754 scopus 로고    scopus 로고
    • Interferon alpha (pegylated and non-pegylated) and ribavirin for the treatment of mild chronic hepatitis C: a systematic review and economic evaluation
    • Shepherd, J., Jones, J., Hartwell, D., Davidson, P., Price, A., Waugh, N., 2007. Interferon alpha (pegylated and non-pegylated) and ribavirin for the treatment of mild chronic hepatitis C: a systematic review and economic evaluation. Health Technol. Assess. 11, 1-205, iii.
    • (2007) Health Technol. Assess. , vol.11 , pp. 1-205
    • Shepherd, J.1    Jones, J.2    Hartwell, D.3    Davidson, P.4    Price, A.5    Waugh, N.6
  • 26
    • 85030415632 scopus 로고    scopus 로고
    • WHO, 2012. http://www.who.int/csr/disease/hepatitis/whocdscsrlyo2003/en/ index4.html.
    • (2012) WHO
  • 28
    • 33144471074 scopus 로고    scopus 로고
    • Production of infectious genotype 1a hepatitis C virus (Hutchinson strain) in cultured human hepatoma cells
    • Yi, M., Villanueva, R.A., Thomas, D.L., Wakita, T., Lemon, S.M., 2006. Production of infectious genotype 1a hepatitis C virus (Hutchinson strain) in cultured human hepatoma cells. Proc. Natl. Acad. Sci. USA 103, 2310-2315.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 2310-2315
    • Yi, M.1    Villanueva, R.A.2    Thomas, D.L.3    Wakita, T.4    Lemon, S.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.