메뉴 건너뛰기




Volumn 8, Issue 5, 2013, Pages

Protection against Myocardial Ischemia-Reperfusion Injury at Onset of Type 2 Diabetes in Zucker Diabetic Fatty Rats Is Associated with Altered Glucose Oxidation

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLYCOGEN;

EID: 84877961256     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0064093     Document Type: Article
Times cited : (42)

References (60)
  • 1
    • 37549038706 scopus 로고    scopus 로고
    • Interaction of cardiovascular risk factors with myocardial ischemia/reperfusion injury, preconditioning, and postconditioning
    • doi:10.1124/pr.107.06002
    • Ferdinandy P, Schulz R, Baxter GF, (2007) Interaction of cardiovascular risk factors with myocardial ischemia/reperfusion injury, preconditioning, and postconditioning. Pharmacol Rev 59: 418-458 doi:10.1124/pr.107.06002.
    • (2007) Pharmacol Rev , vol.59 , pp. 418-458
    • Ferdinandy, P.1    Schulz, R.2    Baxter, G.F.3
  • 2
    • 77249107745 scopus 로고    scopus 로고
    • Remote ischaemic conditioning before hospital admission, as a complement to angioplasty, and effect on myocardial salvage in patients with acute myocardial infarction: a randomised trial
    • doi:10.1016/S0140-6736(09)62001-8
    • Bøtker HE, Kharbanda R, Schmidt MR, Bøttcher M, Kaltoft AK, et al. (2010) Remote ischaemic conditioning before hospital admission, as a complement to angioplasty, and effect on myocardial salvage in patients with acute myocardial infarction: a randomised trial. Lancet 375: 727-734 doi:10.1016/S0140-6736(09)62001-8.
    • (2010) Lancet , vol.375 , pp. 727-734
    • Bøtker, H.E.1    Kharbanda, R.2    Schmidt, M.R.3    Bøttcher, M.4    Kaltoft, A.K.5
  • 3
    • 84863911341 scopus 로고    scopus 로고
    • Release of a humoral circulating cardioprotective factor by remote ischemic preconditioning is dependent on preserved neural pathways in diabetic patients
    • doi:10.1007/s00395-012-0285-1
    • Jensen RV, Støttrup NB, Kristiansen SB, Bøtker HE, (2012) Release of a humoral circulating cardioprotective factor by remote ischemic preconditioning is dependent on preserved neural pathways in diabetic patients. Basic Res Cardiol 107: 285 doi:10.1007/s00395-012-0285-1.
    • (2012) Basic Res Cardiol , vol.107 , pp. 285
    • Jensen, R.V.1    Støttrup, N.B.2    Kristiansen, S.B.3    Bøtker, H.E.4
  • 4
    • 29244441132 scopus 로고    scopus 로고
    • Blockade of electron transport before cardiac ischemia with the reversible inhibitor amobarbital protects rat heart mitochondria
    • doi:10.1124/jpet.105.091702
    • Chen Q, Hoppel CL, Lesnefsky EJ, (2006) Blockade of electron transport before cardiac ischemia with the reversible inhibitor amobarbital protects rat heart mitochondria. J Pharmacol Exp Ther 316: 200-207 doi:10.1124/jpet.105.091702.
    • (2006) J Pharmacol Exp Ther , vol.316 , pp. 200-207
    • Chen, Q.1    Hoppel, C.L.2    Lesnefsky, E.J.3
  • 5
    • 67349236041 scopus 로고    scopus 로고
    • Cardioprotection by metabolic shut-down and gradual wake-up
    • doi:10.1016/j.yjmcc.2009.02.026
    • Burwell LS, Nadtochiy SM, Brookes PS, (2009) Cardioprotection by metabolic shut-down and gradual wake-up. J Mol Cell Cardiol 46: 804-810 doi:10.1016/j.yjmcc.2009.02.026.
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 804-810
    • Burwell, L.S.1    Nadtochiy, S.M.2    Brookes, P.S.3
  • 6
    • 34548746306 scopus 로고    scopus 로고
    • Myocardial reperfusion injury
    • doi:10.1056/NEJMra071667
    • Yellon DM, Hausenloy DJ, (2007) Myocardial reperfusion injury. N Engl J Med 357: 1121-1135 doi:10.1056/NEJMra071667.
    • (2007) N Engl J Med , vol.357 , pp. 1121-1135
    • Yellon, D.M.1    Hausenloy, D.J.2
  • 7
    • 0037025393 scopus 로고    scopus 로고
    • Regulation of glycolytic flux in ischemic preconditioning. A study employing metabolic control analysis
    • doi:10.1074/jbc.M201138200
    • Vogt AM, Poolman M, Ackermann C, Yildiz M, Schoels W, et al. (2002) Regulation of glycolytic flux in ischemic preconditioning. A study employing metabolic control analysis. J Biol Chem 277: 24411-24419 doi:10.1074/jbc.M201138200.
    • (2002) J Biol Chem , vol.277 , pp. 24411-24419
    • Vogt, A.M.1    Poolman, M.2    Ackermann, C.3    Yildiz, M.4    Schoels, W.5
  • 8
    • 12344305124 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and type 2 diabetes
    • doi:10.1126/science.1104343
    • Lowell BB, Shulman GI, (2005) Mitochondrial dysfunction and type 2 diabetes. Science 307: 384-387 doi:10.1126/science.1104343.
    • (2005) Science , vol.307 , pp. 384-387
    • Lowell, B.B.1    Shulman, G.I.2
  • 9
    • 77958096415 scopus 로고    scopus 로고
    • Inhibition of the malate-aspartate shuttle by pre-ischaemic aminooxyacetate loading of the heart induces cardioprotection
    • doi:10.1093/cvr/cvq205
    • Støttrup NB, Løfgren B, Birkler RD, Nielsen JM, Wang L, et al. (2010) Inhibition of the malate-aspartate shuttle by pre-ischaemic aminooxyacetate loading of the heart induces cardioprotection. Cardiovasc Res 88: 257-266 doi:10.1093/cvr/cvq205.
    • (2010) Cardiovasc Res , vol.88 , pp. 257-266
    • Støttrup, N.B.1    Løfgren, B.2    Birkler, R.D.3    Nielsen, J.M.4    Wang, L.5
  • 10
    • 79960808907 scopus 로고    scopus 로고
    • Metabolic fingerprint of ischaemic cardioprotection: importance of the malate-aspartate shuttle
    • doi:10.1093/cvr/cvr051
    • Nielsen TT, Støttrup NB, Løfgren B, Bøtker HE, (2011) Metabolic fingerprint of ischaemic cardioprotection: importance of the malate-aspartate shuttle. Cardiovasc Res 91: 382-391 doi:10.1093/cvr/cvr051.
    • (2011) Cardiovasc Res , vol.91 , pp. 382-391
    • Nielsen, T.T.1    Støttrup, N.B.2    Løfgren, B.3    Bøtker, H.E.4
  • 11
    • 84866788712 scopus 로고    scopus 로고
    • Effects of fatty acids on cardioprotection by pre-ischaemic inhibition of the malate-aspartate shuttle
    • doi:10.1111/j.1440-1681.2012.05749.x
    • Dalgas C, Povlsen JA, Løfgren B, Erichsen SB, Bøtker HE, (2012) Effects of fatty acids on cardioprotection by pre-ischaemic inhibition of the malate-aspartate shuttle. Clin Exp Pharmacol Physiol 39: 878-885 doi:10.1111/j.1440-1681.2012.05749.x.
    • (2012) Clin Exp Pharmacol Physiol , vol.39 , pp. 878-885
    • Dalgas, C.1    Povlsen, J.A.2    Løfgren, B.3    Erichsen, S.B.4    Bøtker, H.E.5
  • 12
    • 34147167011 scopus 로고    scopus 로고
    • Ca2+ Activation kinetics of the two aspartate-glutamate mitochondrial carriers, aralar and citrin: role in the heart malate-aspartate NADH shuttle
    • doi:10.1074/jbc.M610491200
    • Contreras L, Gomez-Puertas P, Iijima M, Kobayashi K, Saheki T, et al. (2007) Ca2+ Activation kinetics of the two aspartate-glutamate mitochondrial carriers, aralar and citrin: role in the heart malate-aspartate NADH shuttle. J Biol Chem 282: 7098-7106 doi:10.1074/jbc.M610491200.
    • (2007) J Biol Chem , vol.282 , pp. 7098-7106
    • Contreras, L.1    Gomez-Puertas, P.2    Iijima, M.3    Kobayashi, K.4    Saheki, T.5
  • 13
    • 17944378173 scopus 로고    scopus 로고
    • Citrin and aralar1 are Ca(2+)-stimulated aspartate/glutamate transporters in mitochondria
    • doi:10.1093/emboj/20.18.5060
    • Palmieri L, Pardo B, Lasorsa FM, del Arco A, Kobayashi K, et al. (2001) Citrin and aralar1 are Ca(2+)-stimulated aspartate/glutamate transporters in mitochondria. EMBO J 20: 5060-5069 doi:10.1093/emboj/20.18.5060.
    • (2001) EMBO J , vol.20 , pp. 5060-5069
    • Palmieri, L.1    Pardo, B.2    Lasorsa, F.M.3    del Arco, A.4    Kobayashi, K.5
  • 14
    • 11244318158 scopus 로고    scopus 로고
    • The malate-aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cells
    • doi:10.1074/jbc.M409303200
    • Rubi B, Del Arco A, Bartley C, Satrústegui J, Maechler P, (2004) The malate-aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cells. J Biol Chem 279: 55659-55666 doi:10.1074/jbc.M409303200.
    • (2004) J Biol Chem , vol.279 , pp. 55659-55666
    • Rubi, B.1    Del Arco, A.2    Bartley, C.3    Satrústegui, J.4    Maechler, P.5
  • 15
    • 18044364838 scopus 로고    scopus 로고
    • Correlation between myocardial malate/aspartate shuttle activity and EAAT1 protein expression in hyper- and hypothyroidism
    • doi:10.1152/ajpheart.00991.2004
    • Ralphe JC, Bedell K, Segar JL, Scholz TD, (2005) Correlation between myocardial malate/aspartate shuttle activity and EAAT1 protein expression in hyper- and hypothyroidism. Am J Physiol Heart Circ Physiol 288: H2521-H2526 doi:10.1152/ajpheart.00991.2004.
    • (2005) Am J Physiol Heart Circ Physiol , vol.288
    • Ralphe, J.C.1    Bedell, K.2    Segar, J.L.3    Scholz, T.D.4
  • 16
    • 69949086741 scopus 로고    scopus 로고
    • Cardioprotective effect of L-glutamate in obese type 2 diabetic Zucker fatty rats
    • doi:10.1111/j.1440-1681.2009.05166.x
    • Povlsen JA, Løfgren B, Rasmussen LE, Nielsen JM, Nørregaard R, et al. (2009) Cardioprotective effect of L-glutamate in obese type 2 diabetic Zucker fatty rats. Clin Exp Pharmacol Physiol 36: 892-898 doi:10.1111/j.1440-1681.2009.05166.x.
    • (2009) Clin Exp Pharmacol Physiol , vol.36 , pp. 892-898
    • Povlsen, J.A.1    Løfgren, B.2    Rasmussen, L.E.3    Nielsen, J.M.4    Nørregaard, R.5
  • 17
    • 74049159056 scopus 로고    scopus 로고
    • Amino acid transamination is crucial for ischaemic cardioprotection in normal and preconditioned isolated rat hearts-focus on L-glutamate
    • doi:10.1113/expphysiol.2009.049452
    • Løfgren B, Povlsen JA, Rasmussen LE, Støttrup NB, Solskov L, et al. (2010) Amino acid transamination is crucial for ischaemic cardioprotection in normal and preconditioned isolated rat hearts-focus on L-glutamate. Exp Physiol 95: 140-152 doi:10.1113/expphysiol.2009.049452.
    • (2010) Exp Physiol , vol.95 , pp. 140-152
    • Løfgren, B.1    Povlsen, J.A.2    Rasmussen, L.E.3    Støttrup, N.B.4    Solskov, L.5
  • 18
    • 77955583916 scopus 로고    scopus 로고
    • A UPLC-MS/MS application for profiling of intermediary energy metabolites in microdialysis samples-a method for high-throughput
    • doi:10.1016/j.jpba.2010.06.005
    • Birkler RID, Støttrup NB, Hermannson S, Nielsen TT, Gregersen N, et al. (2010) A UPLC-MS/MS application for profiling of intermediary energy metabolites in microdialysis samples-a method for high-throughput. J Pharm Biomed Anal 53: 983-990 doi:10.1016/j.jpba.2010.06.005.
    • (2010) J Pharm Biomed Anal , vol.53 , pp. 983-990
    • Birkler, R.I.D.1    Støttrup, N.B.2    Hermannson, S.3    Nielsen, T.T.4    Gregersen, N.5
  • 19
    • 0029913165 scopus 로고    scopus 로고
    • Metabolic fate of glucose in reversible low-flow ischemia of the isolated working rat heart
    • Bolukoglu H, Goodwin GW, Guthrie PH, Carmical SG, Chen TM, et al. (1996) Metabolic fate of glucose in reversible low-flow ischemia of the isolated working rat heart. Am J Physiol 270: H817-H826.
    • (1996) Am J Physiol , vol.270
    • Bolukoglu, H.1    Goodwin, G.W.2    Guthrie, P.H.3    Carmical, S.G.4    Chen, T.M.5
  • 20
    • 0014045293 scopus 로고
    • Glucose-2-t as a tracer for glucose metabolism
    • Katz J, Dunn A, (1967) Glucose-2-t as a tracer for glucose metabolism. Biochemistry 6: 1-5.
    • (1967) Biochemistry , vol.6 , pp. 1-5
    • Katz, J.1    Dunn, A.2
  • 21
    • 0034053077 scopus 로고    scopus 로고
    • Kinetic differences and similarities among 3 tracers of myocardial glucose uptake
    • Doenst T, Taegtmeyer H, (2000) Kinetic differences and similarities among 3 tracers of myocardial glucose uptake. J Nucl Med 41: 488-492.
    • (2000) J Nucl Med , vol.41 , pp. 488-492
    • Doenst, T.1    Taegtmeyer, H.2
  • 22
    • 0015349584 scopus 로고
    • The effects of increased heart work on the tricarboxylate cycle and its interactions with glycolysis in the perfused rat heart
    • Neely JR, Denton RM, England PJ, Randle PJ, (1972) The effects of increased heart work on the tricarboxylate cycle and its interactions with glycolysis in the perfused rat heart. Biochem J 128: 147-159.
    • (1972) Biochem J , vol.128 , pp. 147-159
    • Neely, J.R.1    Denton, R.M.2    England, P.J.3    Randle, P.J.4
  • 23
    • 0029002549 scopus 로고
    • Superiority of acid extractable glycogen for detection of metabolic changes during myocardial ischaemia
    • Bøtker HE, Randsbaek F, Hansen SB, Thomassen A, Nielsen TT, (1995) Superiority of acid extractable glycogen for detection of metabolic changes during myocardial ischaemia. J Mol Cell Cardiol 27: 1325-1332.
    • (1995) J Mol Cell Cardiol , vol.27 , pp. 1325-1332
    • Bøtker, H.E.1    Randsbaek, F.2    Hansen, S.B.3    Thomassen, A.4    Nielsen, T.T.5
  • 24
    • 0347931796 scopus 로고    scopus 로고
    • Contradictory effects of short- and long-term hyperglycemias on ischemic injury of myocardium via intracellular signaling pathway
    • Xu G, Takashi E, Kudo M, Ishiwata T, Naito Z, (2004) Contradictory effects of short- and long-term hyperglycemias on ischemic injury of myocardium via intracellular signaling pathway. Exp Mol Pathol 76: 57-65.
    • (2004) Exp Mol Pathol , vol.76 , pp. 57-65
    • Xu, G.1    Takashi, E.2    Kudo, M.3    Ishiwata, T.4    Naito, Z.5
  • 25
    • 1942422613 scopus 로고    scopus 로고
    • Onset of diabetes in Zucker diabetic fatty (ZDF) rats leads to improved recovery of function after ischemia in the isolated perfused heart
    • doi:10.1152/ajpendo.00295.2003
    • Wang P, Chatham JC, (2004) Onset of diabetes in Zucker diabetic fatty (ZDF) rats leads to improved recovery of function after ischemia in the isolated perfused heart. Am J Physiol Endocrinol Metab 286: E725-E736 doi:10.1152/ajpendo.00295.2003.
    • (2004) Am J Physiol Endocrinol Metab , vol.286
    • Wang, P.1    Chatham, J.C.2
  • 26
    • 0029892187 scopus 로고    scopus 로고
    • The evolution of diabetic response to ischemia/reperfusion and preconditioning in isolated working rat hearts
    • Tosaki A, Engelman DT, Engelman RM, Das DK, (1996) The evolution of diabetic response to ischemia/reperfusion and preconditioning in isolated working rat hearts. Cardiovasc Res 31: 526-536.
    • (1996) Cardiovasc Res , vol.31 , pp. 526-536
    • Tosaki, A.1    Engelman, D.T.2    Engelman, R.M.3    Das, D.K.4
  • 27
    • 0042976384 scopus 로고    scopus 로고
    • Ischemic tolerance of rat hearts in acute and chronic phases of experimental diabetes
    • Ravingerová T, Neckár J, Kolár F, (2003) Ischemic tolerance of rat hearts in acute and chronic phases of experimental diabetes. Mol Cell Biochem 249: 167-174.
    • (2003) Mol Cell Biochem , vol.249 , pp. 167-174
    • Ravingerová, T.1    Neckár, J.2    Kolár, F.3
  • 28
    • 80755153640 scopus 로고    scopus 로고
    • Healing the diabetic heart: does myocardial preconditioning work?
    • doi:10.1016/j.cellsig.2011.09.007
    • Balakumar P, Sharma NK, (2012) Healing the diabetic heart: does myocardial preconditioning work? Cell Signal 24: 53-59 doi:10.1016/j.cellsig.2011.09.007.
    • (2012) Cell Signal , vol.24 , pp. 53-59
    • Balakumar, P.1    Sharma, N.K.2
  • 29
    • 77953435480 scopus 로고    scopus 로고
    • Cardiac and renal function are progressively impaired with aging in Zucker diabetic fatty type II diabetic rats
    • doi:10.4161/oxim.2.5.9831
    • Baynes J, Murray DB, (2009) Cardiac and renal function are progressively impaired with aging in Zucker diabetic fatty type II diabetic rats. Oxid Med Cell Longev 2: 328-334 doi:10.4161/oxim.2.5.9831.
    • (2009) Oxid Med Cell Longev , vol.2 , pp. 328-334
    • Baynes, J.1    Murray, D.B.2
  • 30
    • 0842283309 scopus 로고    scopus 로고
    • Myocardial hypertrophy and enhanced left ventricular contractility in Zucker diabetic fatty rats
    • doi:10.1016/S1054-8807(03)00109-1
    • Fredersdorf S, Thumann C, Ulucan C, Griese DP, Luchner A, et al. (2004) Myocardial hypertrophy and enhanced left ventricular contractility in Zucker diabetic fatty rats. Cardiovasc Pathol 13: 11-19 doi:10.1016/S1054-8807(03)00109-1.
    • (2004) Cardiovasc Pathol , vol.13 , pp. 11-19
    • Fredersdorf, S.1    Thumann, C.2    Ulucan, C.3    Griese, D.P.4    Luchner, A.5
  • 31
    • 70350450977 scopus 로고    scopus 로고
    • Cholesterol diet-induced hyperlipidemia impairs the cardioprotective effect of postconditioning: role of peroxynitrite
    • doi:10.1152/ajpheart.00484.2009
    • Kupai K, Csonka C, Fekete V, Odendaal L, van Rooyen J, et al. (2009) Cholesterol diet-induced hyperlipidemia impairs the cardioprotective effect of postconditioning: role of peroxynitrite. Am J Physiol Heart Circ Physiol 297: H1729-H1735 doi:10.1152/ajpheart.00484.2009.
    • (2009) Am J Physiol Heart Circ Physiol , vol.297
    • Kupai, K.1    Csonka, C.2    Fekete, V.3    Odendaal, L.4    van Rooyen, J.5
  • 32
    • 24944544711 scopus 로고    scopus 로고
    • Hypercholesterolemia attenuates the anti-ischemic effect of preconditioning during coronary angioplasty
    • doi:10.1378/chest.128.3.1623
    • Ungi I, Ungi T, Ruzsa Z, Nagy E, Zimmermann Z, et al. (2005) Hypercholesterolemia attenuates the anti-ischemic effect of preconditioning during coronary angioplasty. Chest 128: 1623-1628 doi:10.1378/chest.128.3.1623.
    • (2005) Chest , vol.128 , pp. 1623-1628
    • Ungi, I.1    Ungi, T.2    Ruzsa, Z.3    Nagy, E.4    Zimmermann, Z.5
  • 33
    • 0028168212 scopus 로고
    • Ischaemic preconditioning protects hypertrophied myocardium
    • Speechly-Dick ME, Baxter GF, Yellon DM, (1994) Ischaemic preconditioning protects hypertrophied myocardium. Cardiovasc Res 28: 1025-1029.
    • (1994) Cardiovasc Res , vol.28 , pp. 1025-1029
    • Speechly-Dick, M.E.1    Baxter, G.F.2    Yellon, D.M.3
  • 34
    • 33846240944 scopus 로고    scopus 로고
    • Attenuated cardioprotective response to bradykinin, but not classical ischaemic preconditioning, in DOCA-salt hypertensive left ventricular hypertrophy
    • doi:10.1016/j.phrs.2006.10.004
    • Ebrahim Z, Yellon DM, Baxter GF, (2007) Attenuated cardioprotective response to bradykinin, but not classical ischaemic preconditioning, in DOCA-salt hypertensive left ventricular hypertrophy. Pharmacol Res 55: 42-48 doi:10.1016/j.phrs.2006.10.004.
    • (2007) Pharmacol Res , vol.55 , pp. 42-48
    • Ebrahim, Z.1    Yellon, D.M.2    Baxter, G.F.3
  • 35
    • 84858446857 scopus 로고    scopus 로고
    • Ischemic conditioning protects the uremic heart in a rodent model of myocardial infarction
    • doi:10.1161/CIRCULATIONAHA.111.055392
    • Byrne CJ, McCafferty K, Kieswich J, Harwood S, Andrikopoulos P, et al. (2012) Ischemic conditioning protects the uremic heart in a rodent model of myocardial infarction. Circulation 125: 1256-1265 doi:10.1161/CIRCULATIONAHA.111.055392.
    • (2012) Circulation , vol.125 , pp. 1256-1265
    • Byrne, C.J.1    McCafferty, K.2    Kieswich, J.3    Harwood, S.4    Andrikopoulos, P.5
  • 36
  • 37
    • 77949340941 scopus 로고    scopus 로고
    • The role of protein O-linked beta-N-acetylglucosamine in mediating cardiac stress responses
    • doi:10.1016/j.bbagen.2009.07.004
    • Chatham JC, Marchase RB, (2010) The role of protein O-linked beta-N-acetylglucosamine in mediating cardiac stress responses. Biochim Biophys Acta 1800: 57-66 doi:10.1016/j.bbagen.2009.07.004.
    • (2010) Biochim Biophys Acta , vol.1800 , pp. 57-66
    • Chatham, J.C.1    Marchase, R.B.2
  • 38
    • 33748907540 scopus 로고    scopus 로고
    • Paradoxically enhanced heart tolerance to ischaemia in type 1 diabetes and role of increased osmolarity
    • doi:10.1111/j.1440-1681.2006.04463.x
    • Chen H, Shen W-L, Wang X-H, Chen H-Z, Gu J-Z, et al. (2006) Paradoxically enhanced heart tolerance to ischaemia in type 1 diabetes and role of increased osmolarity. Clin Exp Pharmacol Physiol 33: 910-916 doi:10.1111/j.1440-1681.2006.04463.x.
    • (2006) Clin Exp Pharmacol Physiol , vol.33 , pp. 910-916
    • Chen, H.1    Shen, W.-L.2    Wang, X.-H.3    Chen, H.-Z.4    Gu, J.-Z.5
  • 39
    • 0037312615 scopus 로고    scopus 로고
    • Different influences of hyperglycemic duration on phosphorylated extracellular signal-regulated kinase 1/2 in rat heart
    • Naito Z, Takashi E, Xu G, Ishiwata T, Teduka K, et al. (2003) Different influences of hyperglycemic duration on phosphorylated extracellular signal-regulated kinase 1/2 in rat heart. Exp Mol Pathol 74: 23-32.
    • (2003) Exp Mol Pathol , vol.74 , pp. 23-32
    • Naito, Z.1    Takashi, E.2    Xu, G.3    Ishiwata, T.4    Teduka, K.5
  • 40
    • 50049129261 scopus 로고    scopus 로고
    • Cardiac mitochondrial alterations observed in hyperglycaemic rats-what can we learn from cell biology?
    • Oliveira PJ, (2005) Cardiac mitochondrial alterations observed in hyperglycaemic rats-what can we learn from cell biology? Curr Diabetes Rev 1: 11-21.
    • (2005) Curr Diabetes Rev , vol.1 , pp. 11-21
    • Oliveira, P.J.1
  • 41
    • 0028791770 scopus 로고
    • Ischemic preconditioning inhibits glycolysis and proton production in isolated working rat hearts
    • Finegan BA, Lopaschuk GD, Gandhi M, Clanachan AS, (1995) Ischemic preconditioning inhibits glycolysis and proton production in isolated working rat hearts. Am J Physiol 269: H1767-H1775.
    • (1995) Am J Physiol , vol.269
    • Finegan, B.A.1    Lopaschuk, G.D.2    Gandhi, M.3    Clanachan, A.S.4
  • 42
    • 34547130863 scopus 로고    scopus 로고
    • The role of mitochondria in protection of the heart by preconditioning
    • doi:10.1016/j.bbabio.2007.05.008
    • Halestrap AP, Clarke SJ, Khaliulin I, (2007) The role of mitochondria in protection of the heart by preconditioning. Biochim Biophys Acta 1767: 1007-1031 doi:10.1016/j.bbabio.2007.05.008.
    • (2007) Biochim Biophys Acta , vol.1767 , pp. 1007-1031
    • Halestrap, A.P.1    Clarke, S.J.2    Khaliulin, I.3
  • 43
    • 0038025371 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in the elderly: possible role in insulin resistance
    • doi:10.1126/science.1082889
    • Petersen KF, Befroy D, Dufour S, Dziura J, Ariyan C, et al. (2003) Mitochondrial dysfunction in the elderly: possible role in insulin resistance. Science 300: 1140-1142 doi:10.1126/science.1082889.
    • (2003) Science , vol.300 , pp. 1140-1142
    • Petersen, K.F.1    Befroy, D.2    Dufour, S.3    Dziura, J.4    Ariyan, C.5
  • 44
    • 0023904443 scopus 로고
    • An assessment of anaerobic metabolism during ischemia and reperfusion in isolated guinea pig heart
    • Pisarenko O, Studneva I, Khlopkov V, Solomatina E, Ruuge E, (1988) An assessment of anaerobic metabolism during ischemia and reperfusion in isolated guinea pig heart. Biochim Biophys Acta 934: 55-63.
    • (1988) Biochim Biophys Acta , vol.934 , pp. 55-63
    • Pisarenko, O.1    Studneva, I.2    Khlopkov, V.3    Solomatina, E.4    Ruuge, E.5
  • 45
    • 68849099655 scopus 로고    scopus 로고
    • Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy
    • doi:10.1096/fj.09-129171
    • Schroeder MA, Atherton HJ, Ball DR, Cole MA, Heather LC, et al. (2009) Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy. FASEB J 23: 2529-2538 doi:10.1096/fj.09-129171.
    • (2009) FASEB J , vol.23 , pp. 2529-2538
    • Schroeder, M.A.1    Atherton, H.J.2    Ball, D.R.3    Cole, M.A.4    Heather, L.C.5
  • 46
    • 0018117909 scopus 로고
    • Metabolic responses to cardiac hypoxia. Increased production of succinate by rabbit papillary muscles
    • Taegtmeyer H, (1978) Metabolic responses to cardiac hypoxia. Increased production of succinate by rabbit papillary muscles. Circ Res 43: 808-815.
    • (1978) Circ Res , vol.43 , pp. 808-815
    • Taegtmeyer, H.1
  • 47
    • 84863244462 scopus 로고    scopus 로고
    • Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway
    • doi:10.1016/j.cmet.2012.01.017
    • Ashrafian H, Czibik G, Bellahcene M, Aksentijević D, Smith AC, et al. (2012) Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway. Cell Metab 15: 361-371 doi:10.1016/j.cmet.2012.01.017.
    • (2012) Cell Metab , vol.15 , pp. 361-371
    • Ashrafian, H.1    Czibik, G.2    Bellahcene, M.3    Aksentijević, D.4    Smith, A.C.5
  • 48
    • 0014787834 scopus 로고
    • Control of the tricarboxylate cycle and its interactions with glycolysis during acetate utilization in rat heart
    • Randle PJ, England PJ, Denton RM, (1970) Control of the tricarboxylate cycle and its interactions with glycolysis during acetate utilization in rat heart. Biochem J 117: 677-695.
    • (1970) Biochem J , vol.117 , pp. 677-695
    • Randle, P.J.1    England, P.J.2    Denton, R.M.3
  • 49
    • 9144227549 scopus 로고    scopus 로고
    • Blockade of electron transport during ischemia protects cardiac mitochondria
    • doi:10.1074/jbc.M409720200
    • Lesnefsky EJ, Chen Q, Moghaddas S, Hassan MO, Tandler B, et al. (2004) Blockade of electron transport during ischemia protects cardiac mitochondria. J Biol Chem 279: 47961-47967 doi:10.1074/jbc.M409720200.
    • (2004) J Biol Chem , vol.279 , pp. 47961-47967
    • Lesnefsky, E.J.1    Chen, Q.2    Moghaddas, S.3    Hassan, M.O.4    Tandler, B.5
  • 50
    • 68549136467 scopus 로고    scopus 로고
    • Reduced TCA flux in diabetic myotubes: A governing influence on the diabetic phenotype?
    • doi:10.1016/j.bbrc.2009.07.064
    • Gaster M, (2009) Reduced TCA flux in diabetic myotubes: A governing influence on the diabetic phenotype? Biochem Biophys Res Commun 387: 651-655 doi:10.1016/j.bbrc.2009.07.064.
    • (2009) Biochem Biophys Res Commun , vol.387 , pp. 651-655
    • Gaster, M.1
  • 52
    • 67349144436 scopus 로고    scopus 로고
    • Decreased levels of metabolic enzymes in pancreatic islets of patients with type 2 diabetes
    • doi:10.1007/s00125-009-1319-6
    • MacDonald MJ, Longacre MJ, Langberg E-C, Tibell A, Kendrick MA, et al. (2009) Decreased levels of metabolic enzymes in pancreatic islets of patients with type 2 diabetes. Diabetologia 52: 1087-1091 doi:10.1007/s00125-009-1319-6.
    • (2009) Diabetologia , vol.52 , pp. 1087-1091
    • MacDonald, M.J.1    Longacre, M.J.2    Langberg, E.-C.3    Tibell, A.4    Kendrick, M.A.5
  • 53
    • 84860134902 scopus 로고    scopus 로고
    • Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury
    • doi:10.1093/cvr/cvs129
    • Ussher JR, Wang W, Gandhi M, Keung W, Samokhvalov V, et al. (2012) Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury. Cardiovasc Res 94: 359-369 doi:10.1093/cvr/cvs129.
    • (2012) Cardiovasc Res , vol.94 , pp. 359-369
    • Ussher, J.R.1    Wang, W.2    Gandhi, M.3    Keung, W.4    Samokhvalov, V.5
  • 54
    • 0037424245 scopus 로고    scopus 로고
    • Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production
    • doi:10.1074/jbc.M210432200
    • Li N, Ragheb K, Lawler G, Sturgis J, Rajwa B, et al. (2003) Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. J Biol Chem 278: 8516-8525 doi:10.1074/jbc.M210432200.
    • (2003) J Biol Chem , vol.278 , pp. 8516-8525
    • Li, N.1    Ragheb, K.2    Lawler, G.3    Sturgis, J.4    Rajwa, B.5
  • 55
    • 84872142020 scopus 로고    scopus 로고
    • Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats
    • doi:10.1186/1475-2840-12-16
    • Sárközy M, Zvara A, Gyémánt N, Fekete V, Kocsis GF, et al. (2013) Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats. Cardiovasc Diabetol 12: 16 doi:10.1186/1475-2840-12-16.
    • (2013) Cardiovasc Diabetol , vol.12 , pp. 16
    • Sárközy, M.1    Zvara, A.2    Gyémánt, N.3    Fekete, V.4    Kocsis, G.F.5
  • 56
    • 0027372106 scopus 로고
    • An imbalance between glycolysis and glucose oxidation is a possible explanation for the detrimental effects of high levels of fatty acids during aerobic reperfusion of ischemic hearts
    • Lopaschuk GD, Wambolt RB, Barr RL, (1993) An imbalance between glycolysis and glucose oxidation is a possible explanation for the detrimental effects of high levels of fatty acids during aerobic reperfusion of ischemic hearts. J Pharmacol Exp Ther 264: 135-144.
    • (1993) J Pharmacol Exp Ther , vol.264 , pp. 135-144
    • Lopaschuk, G.D.1    Wambolt, R.B.2    Barr, R.L.3
  • 57
    • 34548008730 scopus 로고    scopus 로고
    • Reperfusion injury salvage kinase signalling: taking a RISK for cardioprotection
    • doi:10.1007/s10741-007-9026-1
    • Hausenloy DJ, Yellon DM, (2007) Reperfusion injury salvage kinase signalling: taking a RISK for cardioprotection. Heart Fail Rev 12: 217-234 doi:10.1007/s10741-007-9026-1.
    • (2007) Heart Fail Rev , vol.12 , pp. 217-234
    • Hausenloy, D.J.1    Yellon, D.M.2
  • 58
    • 29744456063 scopus 로고    scopus 로고
    • Insulin resistance in the Zucker diabetic fatty rat: a metabolic characterisation of obese and lean phenotypes
    • doi:10.1007/s00592-005-0197-8
    • Leonard BL, Watson RN, Loomes KM, Phillips ARJ, Cooper GJ, (2005) Insulin resistance in the Zucker diabetic fatty rat: a metabolic characterisation of obese and lean phenotypes. Acta Diabetol 42: 162-170 doi:10.1007/s00592-005-0197-8.
    • (2005) Acta Diabetol , vol.42 , pp. 162-170
    • Leonard, B.L.1    Watson, R.N.2    Loomes, K.M.3    Phillips, A.R.J.4    Cooper, G.J.5
  • 59
    • 0032954960 scopus 로고    scopus 로고
    • Metabolic and hemodynamic effects of moxonidine in the Zucker diabetic fatty rat model of type 2 diabetes
    • Yakubu-Madus FE, Johnson WT, Zimmerman KM, Dananberg J, Steinberg MI, (1999) Metabolic and hemodynamic effects of moxonidine in the Zucker diabetic fatty rat model of type 2 diabetes. Diabetes 48: 1093-1100.
    • (1999) Diabetes , vol.48 , pp. 1093-1100
    • Yakubu-Madus, F.E.1    Johnson, W.T.2    Zimmerman, K.M.3    Dananberg, J.4    Steinberg, M.I.5
  • 60
    • 70349617679 scopus 로고    scopus 로고
    • Cardiac and skeletal muscle fatty acid transport and transporters and triacylglycerol and fatty acid oxidation in lean and Zucker diabetic fatty rats
    • doi:10.1152/ajpregu.90820.2008
    • Bonen A, Holloway GP, Tandon NN, Han X-X, McFarlan J, et al. (2009) Cardiac and skeletal muscle fatty acid transport and transporters and triacylglycerol and fatty acid oxidation in lean and Zucker diabetic fatty rats. Am J Physiol Regul Integr Comp Physiol 297: R1202-R1212 doi:10.1152/ajpregu.90820.2008.
    • (2009) Am J Physiol Regul Integr Comp Physiol , vol.297
    • Bonen, A.1    Holloway, G.P.2    Tandon, N.N.3    Han, X.-X.4    McFarlan, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.