메뉴 건너뛰기




Volumn 25, Issue , 2013, Pages 25-40

Genetics of the ghrelin system

Author keywords

[No Author keywords available]

Indexed keywords

GHRELIN; GHRELIN RECEPTOR; GLUCOSE;

EID: 84877940165     PISSN: 14217082     EISSN: 16622979     Source Type: Book Series    
DOI: 10.1159/000348665     Document Type: Article
Times cited : (5)

References (56)
  • 3
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormonereleasing acylated peptide from stomach
    • Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K: Ghrelin is a growth-hormonereleasing acylated peptide from stomach. Nature 1999; 402: 656-660.
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 6
    • 0034880513 scopus 로고    scopus 로고
    • Rapid communications: Mutations in the ghrelin/preproghrelin gene associated with obesity in humans
    • Ukkola O, Ravussen E, Jacobson P, et al: Rapid communications: mutations in the ghrelin/preproghrelin gene associated with obesity in humans. J Clin Endocrinol Metab 2001; 86: 3996-3999.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3996-3999
    • Ukkola, O.1    Ravussen, E.2    Jacobson, P.3
  • 7
    • 4344690017 scopus 로고    scopus 로고
    • Ghrelin gene polymorphisms and ghrelin, insulin, IGF-1, leptin and anthropometric data in children and adolescents
    • Vivenza D, Rapa A, Castellino N, et al: Ghrelin gene polymorphisms and ghrelin, insulin, IGF-1, leptin and anthropometric data in children and adolescents. Eur J Endocrinol 2004; 151: 127-133.
    • (2004) Eur J Endocrinol , vol.151 , pp. 127-133
    • Vivenza, D.1    Rapa, A.2    Castellino, N.3
  • 8
    • 0036688882 scopus 로고    scopus 로고
    • Role of ghrelin polymorphisms in obesity based on three different studies
    • Ukkola O, Ravussen E, Jacobson P, et al: Role of ghrelin polymorphisms in obesity based on three different studies. Obes Res 2002; 10: 782-791.
    • (2002) Obes Res , vol.10 , pp. 782-791
    • Ukkola, O.1    Ravussen, E.2    Jacobson, P.3
  • 10
    • 1542300099 scopus 로고    scopus 로고
    • Molecular screening of the ghrelin gene in Italian obese children: The Leu72Met variant is associated with an earlier onset of obesity
    • Miraglia DG, Santoro N, Cirillo G, et al: Molecular screening of the ghrelin gene in Italian obese children: the Leu72Met variant is associated with an earlier onset of obesity. Int J Obes Relat Metab Disord 2002; 28: 447-450.
    • (2002) Int J Obes Relat Metab Disord , vol.28 , pp. 447-450
    • Miraglia, D.G.1    Santoro, N.2    Cirillo, G.3
  • 11
    • 0036079504 scopus 로고    scopus 로고
    • Ghrelin gene: Identification of missense variants and a frameshift mutation in extremely obese children and adolescents and healthy normal weight students
    • Hinney A, Hoch A, Geller F, et al: Ghrelin gene: identification of missense variants and a frameshift mutation in extremely obese children and adolescents and healthy normal weight students. J Clin Endocrinol Metab 2002; 87: 2716-2719.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 2716-2719
    • Hinney, A.1    Hoch, A.2    Geller, F.3
  • 12
    • 33750434312 scopus 로고    scopus 로고
    • Preproghrelin Leu72Met variant contributes to overweight in middle-aged men of a Japanese large cohort
    • Kuzuya M, Ando F, Iguchi A, Shimokata H: Preproghrelin Leu72Met variant contributes to overweight in middle-aged men of a Japanese large cohort. Int J Obes (Lond) 2006; 30: 1609-1614.
    • (2006) Int J Obes (Lond) , vol.30 , pp. 1609-1614
    • Kuzuya, M.1    Ando, F.2    Iguchi, A.3    Shimokata, H.4
  • 14
    • 35548969770 scopus 로고    scopus 로고
    • Genes, fat intake, and cardiovascular disease risk factors in the Quebec Family Study
    • Robitaille J, Prusse L, Bouchard C, Vohl MC: Genes, fat intake, and cardiovascular disease risk factors in the Quebec Family Study. Obesity (Silver Spring) 2007; 15: 2336-2347.
    • (2007) Obesity (Silver Spring) , vol.15 , pp. 2336-2347
    • Robitaille, J.1    Prusse, L.2    Bouchard, C.3    Vohl, M.C.4
  • 18
    • 34447263548 scopus 로고    scopus 로고
    • Variations in the preproghrelin gene correlate with higher body mass index, fat mass, and body dissatisfaction in young Japanese women
    • Ando T, Ichimaru Y, Konjiki F, Shoji M, Komaki G: Variations in the preproghrelin gene correlate with higher body mass index, fat mass, and body dissatisfaction in young Japanese women. Am J Clin Nutr 2007; 86: 25-32.
    • (2007) Am J Clin Nutr , vol.86 , pp. 25-32
    • Ando, T.1    Ichimaru, Y.2    Konjiki, F.3    Shoji, M.4    Komaki, G.5
  • 20
    • 33748464912 scopus 로고    scopus 로고
    • Sequencing analysis of ghrelin gene 5 ' flanking region: Relations between the sequence variants, fasting plasma total ghrelin concentrations, and body mass index
    • Vartiainen J, Kesaniemi YA, Ukkola O: Sequencing analysis of ghrelin gene 5 ' flanking region: relations between the sequence variants, fasting plasma total ghrelin concentrations, and body mass index. Metabolism 2006; 55: 1420-1425.
    • (2006) Metabolism , vol.55 , pp. 1420-1425
    • Vartiainen, J.1    Kesaniemi, Y.A.2    Ukkola, O.3
  • 22
    • 49349111720 scopus 로고    scopus 로고
    • Polymorphisms of genes coding for ghrelin and its receptor in relation to anthropometry, circulating levels of IGF-I and IGFBP-3, and breast cancer risk: A casecontrol study nested within the European Prospective Investigation into Cancer and Nutrition (EPIC)
    • Dossus L, McKay JD, Canzian F, et al: Polymorphisms of genes coding for ghrelin and its receptor in relation to anthropometry, circulating levels of IGF-I and IGFBP-3, and breast cancer risk: a casecontrol study nested within the European Prospective Investigation into Cancer and Nutrition (EPIC). Carcinogenesis 2008; 29: 1360-1366.
    • (2008) Carcinogenesis , vol.29 , pp. 1360-1366
    • Dossus, L.1    McKay, J.D.2    Canzian, F.3
  • 25
    • 84862646748 scopus 로고    scopus 로고
    • Association of ghrelin receptor promoter polymorphisms with weight loss following Roux-en-Y gastric bypass surgery
    • Matzko ME, Argyropoulos G, Wood GC, Chu X, McCarter RJ, Still CD, Gerhard GS: Association of ghrelin receptor promoter polymorphisms with weight loss following Roux-en-Y gastric bypass surgery. Obes Surg 2012; 22: 783-790.
    • (2012) Obes Surg , vol.22 , pp. 783-790
    • Matzko, M.E.1    Argyropoulos, G.2    Wood, G.C.3    Chu, X.4    McCarter, R.J.5    Still, C.D.6    Gerhard, G.S.7
  • 27
    • 84862732594 scopus 로고    scopus 로고
    • Growth hormone secretagogue receptor (GHSR) gene polymorphishms are associated with stature throughout pregnancy
    • Riedl S, Hughes I, Harris M, Leong GM, Beilby J, Sly P, Choong CS: Growth hormone secretagogue receptor (GHSR) gene polymorphishms are associated with stature throughout pregnancy. Eur J Endocrinol 2012; 166: 1079-1085.
    • (2012) Eur J Endocrinol , vol.166 , pp. 1079-1085
    • Riedl, S.1    Hughes, I.2    Harris, M.3    Leong, G.M.4    Beilby, J.5    Sly, P.6    Choong, C.S.7
  • 29
    • 33646834958 scopus 로고    scopus 로고
    • Case-control and combined family trios analysis of three polymorphisms in the ghrelin gene in European patients with anorexia and bulimia nervosa
    • Cellini E, Nacmias B, Brecelj-Anderluh M, et al: Case-control and combined family trios analysis of three polymorphisms in the ghrelin gene in European patients with anorexia and bulimia nervosa. Psychiatr Genet 2006; 16: 51-52.
    • (2006) Psychiatr Genet , vol.16 , pp. 51-52
    • Cellini, E.1    Nacmias, B.2    Brecelj-Anderluh, M.3
  • 30
    • 33646352977 scopus 로고    scopus 로고
    • No association of the Arg51Gln and Leu-72Met polymorphisms of the ghrelin gene with anorexia nervosa or bulimia nervosa
    • Monteleone P, Tortorella A, Castaldo E, Di Filippo C, Maj M: No association of the Arg51Gln and Leu-72Met polymorphisms of the ghrelin gene with anorexia nervosa or bulimia nervosa. Neurosci Lett 2006; 398: 325-327.
    • (2006) Neurosci Lett , vol.398 , pp. 325-327
    • Monteleone, P.1    Tortorella, A.2    Castaldo, E.3    Di Filippo, C.4    Maj, M.5
  • 33
    • 33845384878 scopus 로고    scopus 로고
    • Possible role of preproghrelin gene polymorphisms in susceptibility to bulimia nervosa
    • Ando T, Komaki G, Naruo T, et al: Possible role of preproghrelin gene polymorphisms in susceptibility to bulimia nervosa. Am J Med Genet B Neuropsychiatr Genet 2006; 141B:929-934.
    • (2006) Am J Med Genet B Neuropsychiatr Genet , vol.141 B , pp. 929-934
    • Ando, T.1    Komaki, G.2    Naruo, T.3
  • 38
    • 42149126035 scopus 로고    scopus 로고
    • A new variation in the promoter region, the -604C>T, and the Leu72Met polymorphism of the ghrelin gene are associated with protection to insulin resistance
    • Zavarella S, Petrone A, Zampetti S, Gueorguiev M, Spoletini M, Mein CA, Leto G, Korbonits M, Buzzetti R: A new variation in the promoter region, the -604C>T, and the Leu72Met polymorphism of the ghrelin gene are associated with protection to insulin resistance. Int J Obes 2008; 32: 663-668.
    • (2008) Int J Obes , vol.32 , pp. 663-668
    • Zavarella, S.1    Petrone, A.2    Zampetti, S.3    Gueorguiev, M.4    Spoletini, M.5    Mein, C.A.6    Leto, G.7    Korbonits, M.8    Buzzetti, R.9
  • 39
    • 57049117340 scopus 로고    scopus 로고
    • The Leu72Met polymorphism of the ghrelin gene is associated with decreased risk for type 2 diabetes
    • Berthold HK, Giannakidou E, Krone W, Mantzoros CS, Gouni-Berthold I: The Leu72Met polymorphism of the ghrelin gene is associated with decreased risk for type 2 diabetes. Clin Chim Acta 2009; 399: 112-116.
    • (2009) Clin Chim Acta , vol.399 , pp. 112-116
    • Berthold, H.K.1    Giannakidou, E.2    Krone, W.3    Mantzoros, C.S.4    Gouni-Berthold, I.5
  • 40
    • 84873750955 scopus 로고    scopus 로고
    • Association between the ghrelin Leu72Met polymorphism and type 2 diabetes risk: A meta-analysis
    • Liao N, Xie ZK, Huang J, Xie ZF: Association between the ghrelin Leu72Met polymorphism and type 2 diabetes risk: a meta-analysis. Gene 2013;pii: S0378-1119(12)01653-8.
    • (2013) Gene
    • Liao, N.1    Xie, Z.K.2    Huang, J.3    Xie, Z.F.4
  • 42
    • 0037955956 scopus 로고    scopus 로고
    • Ghrelin Arg51Gln mutation is a risk factor for Type 2 diabetes and hypertension in a random sample of middle-aged subjects
    • Poykko S, Ukkola O, Kauma H, Savolainen MJ, Kesaniemi YA: Ghrelin Arg51Gln mutation is a risk factor for Type 2 diabetes and hypertension in a random sample of middle-aged subjects. Diabetologia 2003; 46: 455-458.
    • (2003) Diabetologia , vol.46 , pp. 455-458
    • Poykko, S.1    Ukkola, O.2    Kauma, H.3    Savolainen, M.J.4    Kesaniemi, Y.A.5
  • 43
    • 33751522297 scopus 로고    scopus 로고
    • Polymorphisms in the ghrelin gene are associated with serum highdensity lipoprotein cholesterol level and not with type 2 diabetes mellitus in Koreans
    • Choi HJ, Cho YM, Moon MK, Choi HH, Shin HD, Jang HC, Kim SY, Lee HK, Park KS: Polymorphisms in the ghrelin gene are associated with serum highdensity lipoprotein cholesterol level and not with type 2 diabetes mellitus in Koreans. J Clin Endocrinol Metab 2006; 91: 4657-4663.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 4657-4663
    • Choi, H.J.1    Cho, Y.M.2    Moon, M.K.3    Choi, H.H.4    Shin, H.D.5    Jang, H.C.6    Kim, S.Y.7    Lee, H.K.8    Park, K.S.9
  • 44
    • 79951997699 scopus 로고    scopus 로고
    • The ghrelin gene allele 51Q (rs34911341) is a protective factor against the development of gestational diabetes
    • Dos Santos ICR, Frigeri HR, Daga DR: The ghrelin gene allele 51Q (rs34911341) is a protective factor against the development of gestational diabetes. Clin Chim Acta 2010; 411: 886-887.
    • (2010) Clin Chim Acta , vol.411 , pp. 886-887
    • Dos Santos, I.C.R.1    Frigeri, H.R.2    Daga, D.R.3
  • 45
    • 2342473272 scopus 로고    scopus 로고
    • Sequencing analysis of the ghrelin receptor (growth hormone secretagogue receptor type 1a) gene
    • Vartiainen J, Poykko SM, Raisanen T, Kesaniemi YA, Ukkola O: Sequencing analysis of the ghrelin receptor (growth hormone secretagogue receptor type 1a) gene. Eur J Endocrinol 2004; 150: 457-463.
    • (2004) Eur J Endocrinol , vol.150 , pp. 457-463
    • Vartiainen, J.1    Poykko, S.M.2    Raisanen, T.3    Kesaniemi, Y.A.4    Ukkola, O.5
  • 47
    • 45349085082 scopus 로고    scopus 로고
    • Polymorphisms of the ghrelin/obestatin gene and ghrelin levels in Chinese children with short stature
    • Zou CC, Huang K, Liang L, Zhao ZY: Polymorphisms of the ghrelin/obestatin gene and ghrelin levels in Chinese children with short stature. Clin Endocrinol (Oxf) 2008; 69: 99-104.
    • (2008) Clin Endocrinol (Oxf) , vol.69 , pp. 99-104
    • Zou, C.C.1    Huang, K.2    Liang, L.3    Zhao, Z.Y.4
  • 51
    • 77957947562 scopus 로고    scopus 로고
    • Hundreds of variants clustered in genomic loci and biological pathways affect human height
    • Lango Allen H, Estrada K, Lettre G, et al: Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 2010; 467: 832-838.
    • (2010) Nature , vol.467 , pp. 832-838
    • Lango Allen, H.1    Estrada, K.2    Lettre, G.3
  • 55
    • 79951684312 scopus 로고    scopus 로고
    • Identification and functional analysis of novel human growth hormone secretagogue receptor (GHSR) gene mutations in Japanese subjects with short stature
    • Inoue H, Kangawa N, Kinouchi A, Sakamoto Y, Kimura C, Horikawa R, Shigematsu Y, Itakura M, Ogata T, Fujieda K, Japan Growth Genome Consortium: Identification and functional analysis of novel human growth hormone secretagogue receptor (GHSR) gene mutations in Japanese subjects with short stature. J Clin Endocrinol Metab 2011; 96:E373-E378.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. E373-E378
    • Inoue, H.1    Kangawa, N.2    Kinouchi, A.3    Sakamoto, Y.4    Kimura, C.5    Horikawa, R.6    Shigematsu, Y.7    Itakura, M.8    Ogata, T.9    Fujieda, K.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.