Developing rods transplanted into the degenerating retina of Crx-knockout mice exhibit neural activity similar to native photoreceptors

Stem Cells

Volumn 31, Issue 6, 2013, Pages 1149-1159

  Homma, Kohei ^a,b   Okamoto, Satoshi ^a   Mandai, Michiko ^a   Gotoh, Norimoto ^b   Rajasimha, Harsha K ^b   Chang, Yi Sheng ^b,c   Chen, Shan ^b   Li, Wei ^b   Cogliati, Tiziana ^b   Swaroop, Anand ^b   Takahashi, Masayo ^a  

^a RIKEN   (Japan)

^b NATIONAL EYE INSTITUTE   (United States)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Calcium flux; Cell transplantation; Induced pluripotent stem cells; Retinal photoreceptors

Indexed keywords

CALCIUM ION; GREEN FLUORESCENT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CELL TRANSPLANTATION; CONTROLLED STUDY; HYPERPOLARIZATION; MEMBRANE CURRENT; MEMBRANE DEPOLARIZATION; MOUSE; NONHUMAN; PHOTORECEPTOR; PHOTOTRANSDUCTION; RETINA CELL; RETINA DEGENERATION; RETINA GANGLION CELL; RETINA NERVE CELL; RETINA ROD; RETINAL CELL TRANSPLANTATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CALCIUM; CELL DIFFERENTIATION; CELLS, CULTURED; EYE PROTEINS; GREEN FLUORESCENT PROTEINS; HOMEODOMAIN PROTEINS; HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNELS; INDUCED PLURIPOTENT STEM CELLS; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOTORECEPTOR CELLS, VERTEBRATE; PROMOTER REGIONS, GENETIC; RETINA; RETINAL DEGENERATION; RETINAL ROD PHOTORECEPTOR CELLS; STEM CELL TRANSPLANTATION; TRANS-ACTIVATORS;

EID: 84877935484     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1372     Document Type: Article

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