메뉴 건너뛰기




Volumn 319, Issue 10, 2013, Pages 1443-1450

BH3 mimetics reduce adhesion and migration of hepatoblastoma and hepatocellular carcinoma cells

Author keywords

Adhesion; BH3 mimetics; Cdc42; Hepatoblastoma; Migration; Rho GTPases

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; BH3 PROTEIN; CASPASE 3; CASPASE 7; F ACTIN; GUANOSINE TRIPHOSPHATASE; MATRIGEL; OBATOCLAX; PROTEIN CDC42; RHO GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 84877927371     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2013.01.024     Document Type: Article
Times cited : (6)

References (41)
  • 1
    • 0014060328 scopus 로고
    • Hepatoblastoma and hepatocarcinoma in infancy and childhood. Report of 47 cases
    • Ishak K.G., Gunz P.R. Hepatoblastoma and hepatocarcinoma in infancy and childhood. Report of 47 cases. Cancer 1967, 20.
    • (1967) Cancer , pp. 20
    • Ishak, K.G.1    Gunz, P.R.2
  • 2
    • 33645736957 scopus 로고    scopus 로고
    • Surgical treatment of hepatoblastoma in children
    • Czauderna P., et al. Surgical treatment of hepatoblastoma in children. Pediatr. Radiol. 2006, 36(3):187-191.
    • (2006) Pediatr. Radiol. , vol.36 , Issue.3 , pp. 187-191
    • Czauderna, P.1
  • 3
    • 70350333890 scopus 로고    scopus 로고
    • Cisplatin versus cisplatin plus doxorubicin for standard-risk hepatoblastoma
    • Perilongo G., et al. Cisplatin versus cisplatin plus doxorubicin for standard-risk hepatoblastoma. N. Engl. J. Med. 2009, 361(17):1662-1670.
    • (2009) N. Engl. J. Med. , vol.361 , Issue.17 , pp. 1662-1670
    • Perilongo, G.1
  • 4
    • 0034669523 scopus 로고    scopus 로고
    • Cisplatin, doxorubicin, and delayed surgery for childhood hepatoblastoma: a successful approach - results of the first prospective study of the International Society of Pediatric Oncology
    • Pritchard J., et al. Cisplatin, doxorubicin, and delayed surgery for childhood hepatoblastoma: a successful approach - results of the first prospective study of the International Society of Pediatric Oncology. J. Clin. Oncol. 2000, 18(22):3819-3828.
    • (2000) J. Clin. Oncol. , vol.18 , Issue.22 , pp. 3819-3828
    • Pritchard, J.1
  • 5
    • 0027414322 scopus 로고
    • Treatment of pulmonary metastases of initial stage I hepatoblastoma in childhood. Report from the Childrens Cancer Group
    • Feusner J.H., et al. Treatment of pulmonary metastases of initial stage I hepatoblastoma in childhood. Report from the Childrens Cancer Group. Cancer 1993, 71(3):859-864.
    • (1993) Cancer , vol.71 , Issue.3 , pp. 859-864
    • Feusner, J.H.1
  • 6
    • 0029063751 scopus 로고
    • Complete resection before development of drug resistance is essential for survival from advanced hepatoblastoma - a report from the German Cooperative Pediatric Liver Tumor Study HB-89
    • von Schweinitz D., et al. Complete resection before development of drug resistance is essential for survival from advanced hepatoblastoma - a report from the German Cooperative Pediatric Liver Tumor Study HB-89. J. Pediatr. Surg. 1995, 30(6):845-852.
    • (1995) J. Pediatr. Surg. , vol.30 , Issue.6 , pp. 845-852
    • von Schweinitz, D.1
  • 7
    • 0037169358 scopus 로고    scopus 로고
    • Apoptosis: a link between cancer genetics and chemotherapy
    • Johnstone R.W., Ruefli A.A., Lowe S.W. Apoptosis: a link between cancer genetics and chemotherapy. Cell 2002, 108(2):153-164.
    • (2002) Cell , vol.108 , Issue.2 , pp. 153-164
    • Johnstone, R.W.1    Ruefli, A.A.2    Lowe, S.W.3
  • 8
    • 67349252606 scopus 로고    scopus 로고
    • Gene expression profiling reveals signatures characterizing histologic subtypes of hepatoblastoma and global deregulation in cell growth and survival pathways
    • Adesina A.M., et al. Gene expression profiling reveals signatures characterizing histologic subtypes of hepatoblastoma and global deregulation in cell growth and survival pathways. Hum. Pathol. 2009, 40(6):843-853.
    • (2009) Hum. Pathol. , vol.40 , Issue.6 , pp. 843-853
    • Adesina, A.M.1
  • 9
    • 77958591155 scopus 로고    scopus 로고
    • Inhibition of Bcl-2 and Bcl-X enhances chemotherapy sensitivity in hepatoblastoma cells
    • Lieber J., et al. Inhibition of Bcl-2 and Bcl-X enhances chemotherapy sensitivity in hepatoblastoma cells. Pediatr. Blood Cancer 2010, 55(6):1089-1095.
    • (2010) Pediatr. Blood Cancer , vol.55 , Issue.6 , pp. 1089-1095
    • Lieber, J.1
  • 10
    • 63149129655 scopus 로고    scopus 로고
    • Bcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapy
    • Kang M.H., Reynolds C.P. Bcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapy. Clin. Cancer Res. 2009, 15(4):1126-1132.
    • (2009) Clin. Cancer Res. , vol.15 , Issue.4 , pp. 1126-1132
    • Kang, M.H.1    Reynolds, C.P.2
  • 11
    • 68149112387 scopus 로고    scopus 로고
    • Mimicking the BH3 domain to kill cancer cells. Oncogene
    • Chonghaile T.N., Letai A. Mimicking the BH3 domain to kill cancer cells. Oncogene. 27 2008, Suppl 1:S149-S157.
    • (2008) 27 , vol.SUPPL 1
    • Chonghaile, T.N.1    Letai, A.2
  • 12
    • 80051789725 scopus 로고    scopus 로고
    • The BH3 mimetic ABT-737 increases treatment efficiency of paclitaxel against hepatoblastoma
    • Lieber J., et al. The BH3 mimetic ABT-737 increases treatment efficiency of paclitaxel against hepatoblastoma. BMC Cancer 2011, 11(1):362.
    • (2011) BMC Cancer , vol.11 , Issue.1 , pp. 362
    • Lieber, J.1
  • 13
    • 20444486559 scopus 로고    scopus 로고
    • An inhibitor of Bcl-2 family proteins induces regression of solid tumours
    • Oltersdorf T., et al. An inhibitor of Bcl-2 family proteins induces regression of solid tumours. Nature 2005, 435(7042):677-681.
    • (2005) Nature , vol.435 , Issue.7042 , pp. 677-681
    • Oltersdorf, T.1
  • 14
    • 73249118883 scopus 로고    scopus 로고
    • Overview of the molecular bases of resistance to chemotherapy in liver and gastrointestinal tumours
    • Marin J.J., et al. Overview of the molecular bases of resistance to chemotherapy in liver and gastrointestinal tumours. Curr. Mol. Med. 2009, 9(9):1108-1129.
    • (2009) Curr. Mol. Med. , vol.9 , Issue.9 , pp. 1108-1129
    • Marin, J.J.1
  • 15
    • 77957560607 scopus 로고    scopus 로고
    • The BH3-only protein Bad confers breast cancer taxane sensitivity through a nonapoptotic mechanism
    • Craik A.C., et al. The BH3-only protein Bad confers breast cancer taxane sensitivity through a nonapoptotic mechanism. Oncogene 2010, 29(39):5381-5391.
    • (2010) Oncogene , vol.29 , Issue.39 , pp. 5381-5391
    • Craik, A.C.1
  • 16
    • 77950525326 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) induces apoptosis and blocks migration of human medulloblastoma cells
    • Bangaru M.L., et al. Curcumin (diferuloylmethane) induces apoptosis and blocks migration of human medulloblastoma cells. Anticancer Res. 2010, 30(2):499-504.
    • (2010) Anticancer Res. , vol.30 , Issue.2 , pp. 499-504
    • Bangaru, M.L.1
  • 17
    • 78249259696 scopus 로고    scopus 로고
    • Opposing effects of bim and bcl-2 on lung endothelial cell migration
    • Grutzmacher C., et al. Opposing effects of bim and bcl-2 on lung endothelial cell migration. Am. J. Physiol. Lung Cell Mol. Physiol. 2010, 299(5):L607-L620.
    • (2010) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.299 , Issue.5
    • Grutzmacher, C.1
  • 18
    • 78651358342 scopus 로고    scopus 로고
    • Expression of Bmi-1 gene in esophageal carcinoma cell EC9706 and its effect on cell cycle, apoptosis and migration
    • Wang J.F., et al. Expression of Bmi-1 gene in esophageal carcinoma cell EC9706 and its effect on cell cycle, apoptosis and migration. Chin. J. Cancer 2010, 29(7):689-696.
    • (2010) Chin. J. Cancer , vol.29 , Issue.7 , pp. 689-696
    • Wang, J.F.1
  • 19
    • 77249169359 scopus 로고    scopus 로고
    • Bcl-2 overexpression induces a partial epithelial to mesenchymal transition and promotes squamous carcinoma cell invasion and metastasis
    • Zuo J., et al. Bcl-2 overexpression induces a partial epithelial to mesenchymal transition and promotes squamous carcinoma cell invasion and metastasis. Mol. Cancer Res. 2010, 8(2):170-182.
    • (2010) Mol. Cancer Res. , vol.8 , Issue.2 , pp. 170-182
    • Zuo, J.1
  • 20
    • 0029876247 scopus 로고    scopus 로고
    • Cleavage of actin by interleukin 1 beta-converting enzyme to reverse DNase I inhibition
    • Kayalar C., et al. Cleavage of actin by interleukin 1 beta-converting enzyme to reverse DNase I inhibition. Proc. Natl. Acad. Sci. U. S. A. 1996, 93(5):2234-2238.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , Issue.5 , pp. 2234-2238
    • Kayalar, C.1
  • 21
    • 0029758833 scopus 로고    scopus 로고
    • Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis
    • Takahashi A., et al. Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis. Proc. Natl. Acad. Sci. U. S. A. 1996, 93(16):8395-8400.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , Issue.16 , pp. 8395-8400
    • Takahashi, A.1
  • 22
    • 0030820875 scopus 로고    scopus 로고
    • Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis
    • Kothakota S., et al. Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis. Science 1997, 278(5336):294-298.
    • (1997) Science , vol.278 , Issue.5336 , pp. 294-298
    • Kothakota, S.1
  • 23
    • 0036086547 scopus 로고    scopus 로고
    • Caspase 8-mediated cleavage of plectin precedes F-actin breakdown in acinar cells during pancreatitis
    • Beil M., et al. Caspase 8-mediated cleavage of plectin precedes F-actin breakdown in acinar cells during pancreatitis. Am J. Physiol. Gastrointest. Liver Physiol. 2002, 282(3):G450-G460.
    • (2002) Am J. Physiol. Gastrointest. Liver Physiol. , vol.282 , Issue.3
    • Beil, M.1
  • 24
    • 0033491725 scopus 로고    scopus 로고
    • Caspase-3 and caspase-7 but not caspase-6 cleave Gas2 in vitro: implications for microfilament reorganization during apoptosis
    • Sgorbissa A., et al. Caspase-3 and caspase-7 but not caspase-6 cleave Gas2 in vitro: implications for microfilament reorganization during apoptosis. J. Cell Sci. 1999, 112(Pt 23):4475-4482.
    • (1999) J. Cell Sci. , vol.112 , Issue.PART 23 , pp. 4475-4482
    • Sgorbissa, A.1
  • 25
    • 0035375053 scopus 로고    scopus 로고
    • Cdc42 is a substrate for caspases and influences Fas-induced apoptosis
    • Tu S., Cerione R.A. Cdc42 is a substrate for caspases and influences Fas-induced apoptosis. J. Biol. Chem. 2001, 276(22):19656-19663.
    • (2001) J. Biol. Chem. , vol.276 , Issue.22 , pp. 19656-19663
    • Tu, S.1    Cerione, R.A.2
  • 26
    • 0041631013 scopus 로고    scopus 로고
    • Caspase 3-mediated inactivation of rac GTPases promotes drug-induced apoptosis in human lymphoma cells
    • Zhang B., Zhang Y., Shacter E. Caspase 3-mediated inactivation of rac GTPases promotes drug-induced apoptosis in human lymphoma cells. Mol. Cell Biol. 2003, 23(16):5716-5725.
    • (2003) Mol. Cell Biol. , vol.23 , Issue.16 , pp. 5716-5725
    • Zhang, B.1    Zhang, Y.2    Shacter, E.3
  • 27
    • 34250894388 scopus 로고    scopus 로고
    • BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L)
    • Maiuri M.C., et al. BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L). Autophagy 2007, 3(4):374-376.
    • (2007) Autophagy , vol.3 , Issue.4 , pp. 374-376
    • Maiuri, M.C.1
  • 28
    • 79959774131 scopus 로고    scopus 로고
    • Obatoclax induces Atg7-dependent autophagy independent of beclin-1 and BAX/BAK
    • McCoy F., et al. Obatoclax induces Atg7-dependent autophagy independent of beclin-1 and BAX/BAK. Cell Death Dis. 2010, 1:e108.
    • (2010) Cell Death Dis. , vol.1
    • McCoy, F.1
  • 29
    • 84861636323 scopus 로고    scopus 로고
    • Characterisation of the cell line HC-AFW1 derived from a pediatric hepatocellular carcinoma
    • Armeanu-Ebinger S., et al. Characterisation of the cell line HC-AFW1 derived from a pediatric hepatocellular carcinoma. PLoS One 2012, 7(5):e38223.
    • (2012) PLoS One , vol.7 , Issue.5
    • Armeanu-Ebinger, S.1
  • 30
    • 84862250352 scopus 로고    scopus 로고
    • Apoptosis sensitizers enhance cytotoxicity in hepatoblastoma cells
    • Lieber J., et al. Apoptosis sensitizers enhance cytotoxicity in hepatoblastoma cells. Pediatr. Surg. Int. 2012, 28(2):149-159.
    • (2012) Pediatr. Surg. Int. , vol.28 , Issue.2 , pp. 149-159
    • Lieber, J.1
  • 31
    • 34547944751 scopus 로고    scopus 로고
    • Rho GTPases and their regulators in neuronal functions and development
    • Koh C.G. Rho GTPases and their regulators in neuronal functions and development. Neurosignals 2006, 15(5):228-237.
    • (2006) Neurosignals , vol.15 , Issue.5 , pp. 228-237
    • Koh, C.G.1
  • 32
    • 33846578710 scopus 로고    scopus 로고
    • Bcl-2 expression modulates cell adhesion and migration promoting branching of ureteric bud cells
    • Sheibani N., et al. Bcl-2 expression modulates cell adhesion and migration promoting branching of ureteric bud cells. J. Cell Physiol. 2007, 210(3):616-625.
    • (2007) J. Cell Physiol. , vol.210 , Issue.3 , pp. 616-625
    • Sheibani, N.1
  • 33
    • 57049182539 scopus 로고    scopus 로고
    • Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer
    • Cairo S., et al. Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer. Cancer Cell 2008, 14(6):471-484.
    • (2008) Cancer Cell , vol.14 , Issue.6 , pp. 471-484
    • Cairo, S.1
  • 34
    • 84877923881 scopus 로고    scopus 로고
    • Data repository at .
    • Data repository at . http://www.ebi.ac.uk/arrayexpress/experiments/E-MEXP-1851.
  • 35
    • 0027650575 scopus 로고
    • Adhesion molecules in tumor metastasis
    • Zetter B.R. Adhesion molecules in tumor metastasis. Semin. Cancer Biol. 1993, 4(4):219-229.
    • (1993) Semin. Cancer Biol. , vol.4 , Issue.4 , pp. 219-229
    • Zetter, B.R.1
  • 36
    • 0028961293 scopus 로고
    • Rho, rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
    • Nobes C.D., Hall A. Rho, rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 1995, 81(1):53-62.
    • (1995) Cell , vol.81 , Issue.1 , pp. 53-62
    • Nobes, C.D.1    Hall, A.2
  • 37
    • 79958772180 scopus 로고    scopus 로고
    • Cdc42 in oncogenic transformation, invasion, and tumorigenesis
    • Stengel K., Zheng Y. Cdc42 in oncogenic transformation, invasion, and tumorigenesis. Cell Signal 2011, 23(9):1415-1423.
    • (2011) Cell Signal , vol.23 , Issue.9 , pp. 1415-1423
    • Stengel, K.1    Zheng, Y.2
  • 38
    • 78751513758 scopus 로고    scopus 로고
    • The BH3 mimetic ABT-737 induces cancer cell senescence
    • Song J.H., et al. The BH3 mimetic ABT-737 induces cancer cell senescence. Cancer Res. 2011, 71(2):506-515.
    • (2011) Cancer Res. , vol.71 , Issue.2 , pp. 506-515
    • Song, J.H.1
  • 39
    • 0035715879 scopus 로고    scopus 로고
    • Rho family GTPases regulate mammary epithelium cell growth and metastasis through distinguishable pathways
    • Bouzahzah B., et al. Rho family GTPases regulate mammary epithelium cell growth and metastasis through distinguishable pathways. Mol. Med. 2001, 7(12):816-830.
    • (2001) Mol. Med. , vol.7 , Issue.12 , pp. 816-830
    • Bouzahzah, B.1
  • 40
    • 77956523988 scopus 로고    scopus 로고
    • HER2/ErbB2-induced breast cancer cell migration and invasion require p120 catenin activation of Rac1 and Cdc42
    • Johnson E., et al. HER2/ErbB2-induced breast cancer cell migration and invasion require p120 catenin activation of Rac1 and Cdc42. J. Biol. Chem. 2010, 285(38):29491-29501.
    • (2010) J. Biol. Chem. , vol.285 , Issue.38 , pp. 29491-29501
    • Johnson, E.1
  • 41
    • 53249143863 scopus 로고    scopus 로고
    • DOCK10-mediated Cdc42 activation is necessary for amoeboid invasion of melanoma cells
    • Gadea G., et al. DOCK10-mediated Cdc42 activation is necessary for amoeboid invasion of melanoma cells. Curr. Biol. 2008, 18(19):1456-1465.
    • (2008) Curr. Biol. , vol.18 , Issue.19 , pp. 1456-1465
    • Gadea, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.