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Volumn 13, Issue 6, 2013, Pages 817-829

Mesenchymal stem cells protect against neonatal rat hyperoxic lung injury

Author keywords

Apoptosis; Lung injury; Oxygen; Stem cells; Therapy

Indexed keywords

AQUAPORIN 5; GREEN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR; OXYGEN; PHOSPHATE BUFFERED SALINE; PROTEIN BAX; PROTEIN BCL 2; SURFACTANT PROTEIN C; VASCULOTROPIN; AQP5 PROTEIN, RAT; BAX PROTEIN, RAT; PEPTIDE; SFTPC PROTEIN, RAT; VASCULAR ENDOTHELIAL GROWTH FACTOR A, RAT; VASCULOTROPIN A;

EID: 84877899581     PISSN: 14712598     EISSN: None     Source Type: Journal    
DOI: 10.1517/14712598.2013.778969     Document Type: Article
Times cited : (30)

References (48)
  • 1
    • 0031843337 scopus 로고    scopus 로고
    • Functional and pathological effects of prolonged hyperoxia in neonatal mice
    • Warner BB, Stuart LA, Papes RA, et al. Functional and pathological effects of prolonged hyperoxia in neonatal mice. Am J Physiol 1998;275:110-17
    • (1998) Am J Physiol , vol.275 , pp. 110-117
    • Warner, B.B.1    Stuart, L.A.2    Papes, R.A.3
  • 2
    • 33751083331 scopus 로고    scopus 로고
    • Type II epithelial cells are critical target for hyperoxia-mediated impairment of postnatal lung development
    • Yee M, Vitiello PF, Roper JM, et al. Type II epithelial cells are critical target for hyperoxia-mediated impairment of postnatal lung development. Am J Physiol Lung Cell Mol Physiol 2006;291:1101-11
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.291 , pp. 1101-1111
    • Yee, M.1    Vitiello, P.F.2    Roper, J.M.3
  • 3
    • 0038041946 scopus 로고    scopus 로고
    • Alveolar type i cells: Molecular phenotype and development
    • Williams MC. Alveolar type I cells: Molecular phenotype and development. Annu Rev Physiol 2003;65:669-95
    • (2003) Annu Rev Physiol , vol.65 , pp. 669-695
    • Williams, M.C.1
  • 4
    • 0037789187 scopus 로고    scopus 로고
    • Identification of three genes of known function expressed by alveolar epithelial type i cells
    • Qiao R, Zhou B, Liebler JM, et al. Identification of three genes of known function expressed by alveolar epithelial type I cells. Am J Respir Cell Mol Biol 2003;29:98-105
    • (2003) Am J Respir Cell Mol Biol , vol.29 , pp. 98-105
    • Qiao, R.1    Zhou, B.2    Liebler, J.M.3
  • 5
    • 0037376154 scopus 로고    scopus 로고
    • T1alpha, a lung type i cell differentiation gene, is required for normal lung cell proliferation and alveolus formation at birth
    • Ramirez MI, Millien G, Hinds A, et al. T1alpha, a lung type I cell differentiation gene, is required for normal lung cell proliferation and alveolus formation at birth. Dev Biol 2003;256:61-72
    • (2003) Dev Biol , vol.256 , pp. 61-72
    • Ramirez, M.I.1    Millien, G.2    Hinds, A.3
  • 6
    • 0025231434 scopus 로고
    • Isolation and culture of alveolar type II cells
    • Dobbs LG. Isolation and culture of alveolar type II cells. Am J Physiol Lung Cell Mol Physiol 1990;258:134-47
    • (1990) Am J Physiol Lung Cell Mol Physiol , vol.258 , pp. 134-147
    • Dobbs, L.G.1
  • 7
    • 0034915677 scopus 로고    scopus 로고
    • Elevated expression of surfactant proteins in newborn rats during adaptation to hyperoxia
    • White CW, Greene KE, Allen CB, et al. Elevated expression of surfactant proteins in newborn rats during adaptation to hyperoxia. Am J Respir Cell Mol Biol 2001;25:51-9
    • (2001) Am J Respir Cell Mol Biol , vol.25 , pp. 51-59
    • White, C.W.1    Greene, K.E.2    Allen, C.B.3
  • 8
    • 0037662638 scopus 로고    scopus 로고
    • Effects of hyperoxia on VEGF, its receptors, and HIF-2alpha in the newborn rat lung
    • Hosford GE, Olson DM. Effects of hyperoxia on VEGF, its receptors, and HIF-2alpha in the newborn rat lung. Am J Respir Cell Mol Biol 2003;285:161-8
    • (2003) Am J Respir Cell Mol Biol , vol.285 , pp. 161-168
    • Hosford, G.E.1    Olson, D.M.2
  • 9
    • 11144287205 scopus 로고    scopus 로고
    • Role of oxygen and vascular development in epithelial branching morphogenesis of the developing mouse lung
    • Tuyl M, Liu J, Wang J, et al. Role of oxygen and vascular development in epithelial branching morphogenesis of the developing mouse lung. Am J Physiol Lung Cell Mol Physiol 2005;288:167-78
    • (2005) Am J Physiol Lung Cell Mol Physiol , vol.288 , pp. 167-178
    • Tuyl, M.1    Liu, J.2    Wang, J.3
  • 11
    • 27144509839 scopus 로고    scopus 로고
    • Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: Evidence that angiogenesis participates in alveolarization
    • Thebaud B, Ladha F, Michelakis ED, et al. Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: Evidence that angiogenesis participates in alveolarization. Circulation 2005;112:2477-86
    • (2005) Circulation , vol.112 , pp. 2477-2486
    • Thebaud, B.1    Ladha, F.2    Michelakis, E.D.3
  • 12
    • 34247572370 scopus 로고    scopus 로고
    • VEGF-induced heme oxygenase-1 confers cytoprotection from lethal hyperoxia in vivo
    • Siner JM, Jiang G, Cohen ZI, et al. VEGF-induced heme oxygenase-1 confers cytoprotection from lethal hyperoxia in vivo. FASEB J 2007;21:1422-32
    • (2007) FASEB J , vol.21 , pp. 1422-1432
    • Siner, J.M.1    Jiang, G.2    Cohen, Z.I.3
  • 13
    • 28644447579 scopus 로고    scopus 로고
    • Pulmonary and systemic nitric oxide metabolites in ababoon model of neonatal chronic lung disease
    • Munson DA, Grubb PH, Kerecman JD, et al. Pulmonary and systemic nitric oxide metabolites in ababoon model of neonatal chronic lung disease. Am J Respir Cell Mol Biol 2005;33:582-8
    • (2005) Am J Respir Cell Mol Biol , vol.33 , pp. 582-588
    • Munson, D.A.1    Grubb, P.H.2    Kerecman, J.D.3
  • 14
    • 33750842076 scopus 로고    scopus 로고
    • Differential roles of vascular endothelial growth factor receptor-1 and receptor-2 in angiogenesis
    • Shibuya M. Differential roles of vascular endothelial growth factor receptor-1 and receptor-2 in angiogenesis. J Biochem Mol Biol 2006;39:469-78
    • (2006) J Biochem Mol Biol , vol.39 , pp. 469-478
    • Shibuya, M.1
  • 15
    • 63649120377 scopus 로고    scopus 로고
    • Pulmonary expression of vascular endothelial growth factor (VEGF) and alveolar septation in a newborn rat model exposed to acute hypoxia and recovered under conditions of air or hyperoxia
    • Remesal A, Pedraz C, San Feliciano L, et al. Pulmonary expression of vascular endothelial growth factor (VEGF) and alveolar septation in a newborn rat model exposed to acute hypoxia and recovered under conditions of air or hyperoxia. Histol Histopathol 2009;24:325-30
    • (2009) Histol Histopathol , vol.24 , pp. 325-330
    • Remesal, A.1    Pedraz, C.2    San Feliciano, L.3
  • 16
    • 24344448730 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells in repair of the injured lung
    • Rojas M, Xu J, Woods CR, et al. Bone marrow-derived mesenchymal stem cells in repair of the injured lung. Am J Respir Cell Mol Biol 2005;33:145-52
    • (2005) Am J Respir Cell Mol Biol , vol.33 , pp. 145-152
    • Rojas, M.1    Xu, J.2    Woods, C.R.3
  • 17
    • 0037478581 scopus 로고    scopus 로고
    • Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects
    • Ortiz LA, Gambelli F, McBride C, et al. Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects. Proc Natl Acad Sci USA 2003;100:8407-11
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8407-8411
    • Ortiz, L.A.1    Gambelli, F.2    McBride, C.3
  • 18
    • 42049123439 scopus 로고    scopus 로고
    • Bone marrow progenitor cells contribute to repair and remodeling of the lung and heart in a rat model of progressive pulmonary hypertension
    • Spees JL, Whitney MJ, Sullivan DE, et al. Bone marrow progenitor cells contribute to repair and remodeling of the lung and heart in a rat model of progressive pulmonary hypertension. FASEB J 2008;22:1226-36
    • (2008) FASEB J , vol.22 , pp. 1226-1236
    • Spees, J.L.1    Whitney, M.J.2    Sullivan, D.E.3
  • 19
    • 34848853276 scopus 로고    scopus 로고
    • Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1
    • Mei SH, McCarter SD, Deng Y, et al. Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1. PLoS Med 2007;4:e269
    • (2007) PLoS Med , vol.4
    • Mei, S.H.1    McCarter, S.D.2    Deng, Y.3
  • 20
    • 34447511526 scopus 로고    scopus 로고
    • Prevention of endotoxin induced systemic response by bone marrow-derived mesenchymal stem cells in mice
    • Xu J, Woods CR, Mora AL, et al. Prevention of endotoxin induced systemic response by bone marrow-derived mesenchymal stem cells in mice. Am J Physiol Lung Cell Mol Physiol 2007;293:131-41
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.293 , pp. 131-141
    • Xu, J.1    Woods, C.R.2    Mora, A.L.3
  • 21
    • 34548610480 scopus 로고    scopus 로고
    • Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice
    • Gupta N, Su X, Popov B, et al. Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice. J Immunol 2007;179:1855-63
    • (2007) J Immunol , vol.179 , pp. 1855-1863
    • Gupta, N.1    Su, X.2    Popov, B.3
  • 22
    • 70349408786 scopus 로고    scopus 로고
    • Potential application of mesenchymal stem cells in acute lung injury
    • Lee JW, Gupta N, Serikov V, et al. Potential application of mesenchymal stem cells in acute lung injury. Expert Opin Biol Ther 2009;9:1259-70
    • (2009) Expert Opin Biol Ther , vol.9 , pp. 1259-1270
    • Lee, J.W.1    Gupta, N.2    Serikov, V.3
  • 23
    • 24944586369 scopus 로고    scopus 로고
    • Repopulation of human pulmonary epithelium by bone marrow cells: A potential means to promote repair
    • Albera C, Polak JM, Janes S, et al. Repopulation of human pulmonary epithelium by bone marrow cells: A potential means to promote repair. Tissue Eng 2005;11:1115-21
    • (2005) Tissue Eng , vol.11 , pp. 1115-1121
    • Albera, C.1    Polak, J.M.2    Janes, S.3
  • 24
    • 59749100262 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells: Isolation, expansion, characterization, viral transduction, and production of conditioned medium
    • Gnecchi M, Melo LG. Bone marrow-derived mesenchymal stem cells: Isolation, expansion, characterization, viral transduction, and production of conditioned medium. Methods Mol Biol 2009;482:281-94
    • (2009) Methods Mol Biol , vol.482 , pp. 281-294
    • Gnecchi, M.1    Melo, L.G.2
  • 25
    • 33747713246 scopus 로고    scopus 로고
    • Minimal criteria for defining multipotent mesenchymal stromal cells the International Society for Cellular Therapy position statement
    • Dominici M, Le Blanc K, Mueller I, et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 2006;8:315-17
    • (2006) Cytotherapy , vol.8 , pp. 315-317
    • Dominici, M.1    Le Blanc, K.2    Mueller, I.3
  • 26
    • 84864583293 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells attenuate lung inflammation of hyperoxic newborn rats
    • Zhang H, Fang J, Su H, et al. Bone marrow mesenchymal stem cells attenuate lung inflammation of hyperoxic newborn rats. Pediatr Transplant 2012;16:589-98
    • (2012) Pediatr Transplant , Issue.16 , pp. 589-598
    • Zhang, H.1    Fang, J.2    Su, H.3
  • 27
    • 57349114005 scopus 로고    scopus 로고
    • Glutathione reductase targeted to type II cells does not protect mice from hyperoxic lung injury
    • Heyob KM, Rogers LK, Welty SE. Glutathione reductase targeted to type II cells does not protect mice from hyperoxic lung injury. Am J Respir Cell Mol Biol 2008;39:683-8
    • (2008) Am J Respir Cell Mol Biol , vol.39 , pp. 683-688
    • Heyob, K.M.1    Rogers, L.K.2    Welty, S.E.3
  • 28
    • 0023094943 scopus 로고
    • Chronic vascular pulmonary dysplasia associated with neonatal hyperoxia exposure in the rat
    • Shaffer SG, O'Neill D, Bradt SK, et al. Chronic vascular pulmonary dysplasia associated with neonatal hyperoxia exposure in the rat. Pediatr Res 1987;21:14-20
    • (1987) Pediatr Res , vol.21 , pp. 14-20
    • Shaffer, S.G.1    O'Neill, D.2    Bradt, S.K.3
  • 29
    • 0034659494 scopus 로고    scopus 로고
    • Role of aquaporins in alveolar fluid clearance in neonatal and adult lung, and in oedema formation following acute lung injury: Studies in transgenic aquaporin null mice
    • Song Y, Fukuda N, Bai C, et al. Role of aquaporins in alveolar fluid clearance in neonatal and adult lung, and in oedema formation following acute lung injury: Studies in transgenic aquaporin null mice. J Physiol 2000;525:771-9
    • (2000) J Physiol , vol.525 , pp. 771-779
    • Song, Y.1    Fukuda, N.2    Bai, C.3
  • 30
    • 0033987856 scopus 로고    scopus 로고
    • Lung fluid transport in aquaporin5 knockout mice
    • Ma T, Fukuda N, Song Y, et al. Lung fluid transport in aquaporin5 knockout mice. J Clin Investig 2000;105:93-100
    • (2000) J Clin Investig , vol.105 , pp. 93-100
    • Ma, T.1    Fukuda, N.2    Song, Y.3
  • 31
    • 0036090002 scopus 로고    scopus 로고
    • Deficiency of SP-B reveals protective role of SP-C during oxygen lung injury
    • Ikegami M, Weaver TE, Conkright JJ, et al. Deficiency of SP-B reveals protective role of SP-C during oxygen lung injury. J Appl Physiol 2002;92:519-26
    • (2002) J Appl Physiol , vol.92 , pp. 519-526
    • Ikegami, M.1    Weaver, T.E.2    Conkright, J.J.3
  • 32
    • 0033142025 scopus 로고    scopus 로고
    • Brief 95% O2 exposure effects on surfactant protein and mRNA in rat alveolar and bronchiolar epithelium
    • Allred TF, Mercer RR, Thomas RF, et al. Brief 95% O2 exposure effects on surfactant protein and mRNA in rat alveolar and bronchiolar epithelium. Am J Physiol Lung Cell Mol Physiol 1999;276:999-1009
    • (1999) Am J Physiol Lung Cell Mol Physiol , vol.276 , pp. 999-1009
    • Allred, T.F.1    Mercer, R.R.2    Thomas, R.F.3
  • 33
    • 85047690540 scopus 로고    scopus 로고
    • Stat-3 is required for pulmonary homeostasis during hyperoxia
    • Hokuto I, Ikegami M, Yoshida M, et al. Stat-3 is required for pulmonary homeostasis during hyperoxia. J Clin Invest 2004;113:28-37
    • (2004) J Clin Invest , vol.113 , pp. 28-37
    • Hokuto, I.1    Ikegami, M.2    Yoshida, M.3
  • 34
    • 0033814135 scopus 로고    scopus 로고
    • Signal transduction pathways in hyperoxia induced lung cell death
    • Mantell LL, Lee PJ. Signal transduction pathways in hyperoxia induced lung cell death. Mol Genet Metab 2000;71:359-70
    • (2000) Mol Genet Metab , vol.71 , pp. 359-370
    • Mantell, L.L.1    Lee, P.J.2
  • 36
    • 34548851154 scopus 로고    scopus 로고
    • Thioredoxin-1 protects against hyperoxia-induced apoptosisin cells of the alveolar walls
    • Yamada T, Iwasaki Y, Nagata K, et al. Thioredoxin-1 protects against hyperoxia-induced apoptosisin cells of the alveolar walls. Pulm Pharmacol Ther 2007;20:650-9
    • (2007) Pulm Pharmacol Ther , vol.20 , pp. 650-659
    • Yamada, T.1    Iwasaki, Y.2    Nagata, K.3
  • 37
    • 1342347864 scopus 로고    scopus 로고
    • Alveolar cell death in hyperoxia induced lung injury
    • Pagano A, Barazzone-Argiroffo C. Alveolar cell death in hyperoxia induced lung injury. Ann NY Acad Sci 2003;1010:405-16
    • (2003) Ann NY Acad Sci , vol.1010 , pp. 405-416
    • Pagano, A.1    Barazzone-Argiroffo, C.2
  • 38
    • 70349117324 scopus 로고    scopus 로고
    • IL-6 Protects against hyperoxia-induced mitochondrial damage via Bcl-2-induced Bak interactions with mitofusions
    • Waxman AB, Kolliputi N. IL-6 Protects against hyperoxia-induced mitochondrial damage via Bcl-2-induced Bak interactions with mitofusions. Am J Respir Cell Mol Biol 2009;41:385-96
    • (2009) Am J Respir Cell Mol Biol , vol.41 , pp. 385-396
    • Waxman, A.B.1    Kolliputi, N.2
  • 39
    • 57349187606 scopus 로고    scopus 로고
    • The Fas system confers protection against alveolar disruption in hyperoxia-exposed newborn mice
    • Mao Q, Gundavarapu S, Patel C, et al. The Fas system confers protection against alveolar disruption in hyperoxia-exposed newborn mice. Am J Respir Cell Mol Biol 2008;39:717-29
    • (2008) Am J Respir Cell Mol Biol , vol.39 , pp. 717-729
    • Mao, Q.1    Gundavarapu, S.2    Patel, C.3
  • 40
    • 33847642071 scopus 로고    scopus 로고
    • Bcl-2 protects against hyperoxia-induced apoptosis through inhibition of the mitochondria-dependent pathway
    • Metrailler-Ruchonnet I, Pagano A, Carnesecchi S, et al. Bcl-2 protects against hyperoxia-induced apoptosis through inhibition of the mitochondria-dependent pathway. Free Radic Biol Med 2007;42:1062-74
    • (2007) Free Radic Biol Med , vol.42 , pp. 1062-1074
    • Metrailler-Ruchonnet, I.1    Pagano, A.2    Carnesecchi, S.3
  • 41
    • 0033660171 scopus 로고    scopus 로고
    • Inhibition of VEGF receptors causes lung cell apoptosis and emphysema
    • Kasahara Y, Tuder RM, Taraseviciene-Stewart L, et al. Inhibition of VEGF receptors causes lung cell apoptosis and emphysema. J Clin Invest 2000;106:1311-19
    • (2000) J Clin Invest , vol.106 , pp. 1311-1319
    • Kasahara, Y.1    Tuder, R.M.2    Taraseviciene-Stewart, L.3
  • 42
    • 0032993335 scopus 로고    scopus 로고
    • Exposure to hyperoxia decreases the expression of vascular endothelial growth factor and its receptors in adult rat lungs
    • Klekamp JG, Jarzecka K, Perkett EA. Exposure to hyperoxia decreases the expression of vascular endothelial growth factor and its receptors in adult rat lungs. Am J Pathol 1999;154:823-31
    • (1999) Am J Pathol , vol.154 , pp. 823-831
    • Klekamp, J.G.1    Jarzecka, K.2    Perkett, E.A.3
  • 43
    • 77249157301 scopus 로고    scopus 로고
    • Bone marrow-derived angiogenic cells restore lung alveolar and vascular structure after neonatal hyperoxia in infant mice
    • Balasubramaniam V, Ryan SL, Seedorf GJ, et al. Bone marrow-derived angiogenic cells restore lung alveolar and vascular structure after neonatal hyperoxia in infant mice. Am J Physiol Lung Cell Mol Physiol 2010;298:315-23
    • (2010) Am J Physiol Lung Cell Mol Physiol , Issue.298 , pp. 315-323
    • Balasubramaniam, V.1    Ryan, S.L.2    Seedorf, G.J.3
  • 44
    • 70449671455 scopus 로고    scopus 로고
    • Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats
    • van Haaften T, Bryne R, Bonnet S, et al. Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats. Am J Respir Crit Care Med 2009;180:1131-42
    • (2009) Am J Respir Crit Care Med , vol.180 , pp. 1131-1142
    • Van Haaften, T.1    Bryne, R.2    Bonnet, S.3
  • 45
    • 70449686885 scopus 로고    scopus 로고
    • Bone marrow stromal cells attenuate lung injury in a murine model of neonatal chronic lung disesase
    • Aslam M, Baveja R, Liang OD, et al. Bone marrow stromal cells attenuate lung injury in a murine model of neonatal chronic lung disesase. Am J Respir Crit Care Med 2009;180:1122-30
    • (2009) Am J Respir Crit Care Med , vol.180 , pp. 1122-1130
    • Aslam, M.1    Baveja, R.2    Liang, O.D.3
  • 46
    • 34547402979 scopus 로고    scopus 로고
    • Interleukin 1 receptor antagonist mediated the anti-inflammatory and antifibrotic effects of MSCs during acute lung injury
    • Ortiz LA, Dutreil M, Fattman C, et al. Interleukin 1 receptor antagonist mediated the anti-inflammatory and antifibrotic effects of MSCs during acute lung injury. Proc Natl Acad Sci USA 2007;104:11002-7
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 11002-11007
    • Ortiz, L.A.1    Dutreil, M.2    Fattman, C.3
  • 47
    • 67649171661 scopus 로고    scopus 로고
    • Intravenous hmscs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6
    • Lee RH, Pulin AA, Seo MJ, et al. Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6. Cell Stem Cell 2009;5:54-63
    • (2009) Cell Stem Cell , vol.5 , pp. 54-63
    • Lee, R.H.1    Pulin, A.A.2    Seo, M.J.3
  • 48
    • 70349392958 scopus 로고    scopus 로고
    • Allogeneic human mesenchymal stem cells for treatment of e coli endotoxin-induced acute lung injury in the perfused human lung
    • Lee JW, Fang X, Gupta N, et al. Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the perfused human lung. Proc Natl Acad Sci USA 2009;106:16357-62
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 16357-16362
    • Lee, J.W.1    Fang, X.2    Gupta, N.3


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