Pulmonary and systemic nitric oxide metabolites in a baboon model of neonatal chronic lung disease

American Journal of Respiratory Cell and Molecular Biology

Volumn 33, Issue 6, 2005, Pages 582-588

  Munson, David A ^b   Grubb, Peter H ^b   Kerecman, Jay D ^b   McCurnin, Donald C ^b   Yoder, Bradley A ^b   Hazen, Stanley L ^b   Shaul, Philip W ^b   Ischiropoulos, Harry ^a  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b NONE

Author keywords

3 nitrotyrosine; Baboon; Chronic lung disease; Nitric oxide; Prematurity; S nitrosocysteine; S nitrosothiols

Indexed keywords

3 NITROTYROSINE; NITRATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRITE; S NITROSOCYSTEINE; S NITROSOTHIOL;

AIRWAY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; BABOON; BLOOD LEVEL; CHRONIC LUNG DISEASE; CONTROLLED STUDY; DELIVERY; DISEASE MARKER; ENZYME ACTIVITY; FEMALE; FETUS; GESTATIONAL AGE; LUNG DEVELOPMENT; METABOLITE; NEWBORN; NEWBORN DISEASE; NONHUMAN; PREMATURITY; PRENATAL DEVELOPMENT; PRENATAL EXPOSURE; PROTEIN EXPRESSION;

ADMINISTRATION, INHALATION; ANIMALS; ANIMALS, NEWBORN; CHRONIC DISEASE; CYSTEINE; DISEASE MODELS, ANIMAL; FEMALE; FETUS; FREE RADICAL SCAVENGERS; LUNG; LUNG DISEASES; NITRATES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE III; NITRITES; PAPIO; PREGNANCY; S-NITROSOTHIOLS; TYROSINE;

ANIMALIA; PAPIO HAMADRYAS;

EID: 28644447579     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2005-0182OC     Document Type: Article

References (34)

1. Cummings JJ. Nitric oxide decreases lung liquid production in fetal lambs. J Appl Physiol 1997;83:1538-1544.
2. Jakupaj M, Martin RJ, Dreshaj IA, Potter CF, Haxhiu MA, Ernsberger P. Role of endogenous NO in modulating airway contraction mediated by muscarinic receptors during development. Am J Physiol 1997;273: L531-L536.
3. Cummings JJ. Pulmonary vasodilator drugs decrease lung liquid production in fetal sheep. J Appl Physiol 1995;79:1212-1218.
4. Cummings JJ, Wang H. Nitric oxide decreases lung liquid production via guanosine 3′,5′-cyclic monophosphate. Am J Physiol Lung Cell Mol Physiol 2001;280:L923-L929.
5. Potter CF, Dreshaj IA, Haxhiu MA, Stork EK, Chatburn RL, Martin RJ. Effect of exogenous and endogenous nitric oxide on the airway and tissue components of lung resistance in the newborn piglet. Pediatr Res 1997;41:886-891.
6. Schreiber MD, Gin-Mestan K, Marks JD, Huo D, Lee G, Srisuparp P. Inhaled nitric oxide in premature infants with the respiratory distress syndrome. N Engl J Med 2003;349:2099-2107.
7. Parker TA, le Cras TD, Kinsella JP, Abman SH. Developmental changes in endothelial nitric oxide synthase expression and activity in ovine fetal lung. Am J Physiol Lung Cell Mol Physiol 2000;278:L202-L208.
8. Sherman TS, Chen Z, Yuhanna IS, Lau KS, Margraf LR, Shaul PW. Nitric oxide synthase isoform expression in the developing lung epithelium. Am J Physiol 1999;276:L383-L390.
9. Shaul PW, Afshar S, Gibson LL, Sherman TS, Kerecman JD, Grubb PH, Yoder BA, McCurnin DC. Developmental changes in nitric oxide synthase isoform expression and nitric oxide production in fetal baboon lung. Am J Physiol Lung Cell Mol Physiol 2002;283:L1192-L1199.
10. Afshar S, Gibson LL, Yuhanna IS, Sherman TS, Kerecman JD, Grubb PH, Yoder BA, McCurnin DC, Shaul PW. Pulmonary NO synthase expression is attenuated in a fetal baboon model of chronic lung disease. Am J Physiol Lung Cell Mol Physiol 2003;284:L749-L758.
11. McCurnin DC, Pierce RA, Chang LY, Gibson LL, Osborne-Lawrence S, Yoder BA, Kerecman JD, Albertine KH, Winter VT, Coalson JJ, et al. Inhaled NO improves early pulmonary function and modifies lung growth and elastin deposition in a baboon model of neonatal chronic lung disease. Am J Physiol Lung Cell Mol Physiol 2005;288:L450-L459.
12. Coalson JJ, Winter VT, Siler-Khodr T, Yoder BA. Neonatal chronic lung disease in extremely immature baboons. Am J Respir Crit Care Med 1999;160:1333-1346.
13. Shishehbor MH, Aviles RJ, Brennan ML, Fu X, Goormastic M, Pearce GL, Gokce N, Keaney JF Jr, Penn MS, Sprecher DL, et al. Association of nitrotyrosine levels with cardiovascular disease and modulation by statin therapy. JAMA 2003;289:1675-1680.
14. Brennan ML, Wu W, Fu X, Shen Z, Song W, Frost H, Vadseth C, Narine L, Lenkiewicz E, Borchers MT, et al. A tale of two controversies: defining both the role of peroxidases in nitrotyrosine formation in vivo using eosinophil peroxidase and myeloperoxidase-deficient mice, and the nature of peroxidase-generated reactive nitrogen species. J Biol Chem 2002;277:17415- 17427.
15. Fries DM, Paxinou E, Themistocleous M, Swanberg E, Griendling KK, Salvemini D, Slot JW, Heijnen HF, Hazen SL, Ischiropoulos H. Expression of inducible nitric oxide synthase and intracellular protein tyrosine nitration in vascular smooth muscle cells: role of reactive oxygen species. J Biol Chem 2003;278:22901-22907.
16. McCurnin DC, Pierce RA, Chang LY, Gibson LL, Osborne-Lawrence S, Yoder BA, Kerecman JD, Albertine KH, Winter VT, Coalson JJ, et al. Inhaled NO improves early pulmonary function and modifies lung growth and elastin deposition in a baboon model of neonatal chronic lung disease. Am J Physiol Lung Cell Mol Physiol 2005;288: L450-L459.
17. Furfine ES, Harmon MF, Paith JE, Knowles RG, Salter M, Kiff RJ, Duffy C, Hazelwood R, Oplinger JA, Garvey EP. Potent and selective inhibition of human nitric oxide synthases: selective inhibition of neuronal nitric oxide synthase by S-methyl-L-thiocitrulline and S-ethyl-L-thiocitrulline. J Biol Chem 1994;269:26677-26683.
18. Hess DT, Matsumoto A, Kim SO, Marshall HE, Stamler JS. Protein S-nitrosylation: purview and parameters. Nat Rev Mol Cell Biol 2005; 6:150-166.
19. Parks NJ, Krohn KA, Mathis CA, Chasko JH, Geiger KR, Grecor MA, Peek NF. Nitrogen-13-labeled nitrite and nitrate: distribution an metabolism after intratracheal administration. Science 1981;212:58-61.
20. Abman SH, Chatfield BA, Hall SL, McMurtry IF. Role of endothelium-derived relaxing factor during transition of pulmonary circulation at birth. Am J Physiol 1990;259:H1921-H1927.
21. Cornfield DN, Chatfield BA, McQueston JA, McMurtry IF, Abman SH. Effects of birth-related stimuli on L-arginine-dependent pulmonary vasodilation in ovine fetus. Am J Physiol 1992;262:H1474-H1481.
22. Jobe AH, Bancalari E. Bronchopulmonary dysplasia. Am J Respir Crit Care Med 2001;163:1723-1729.
23. Lorch SA, Banks BA, Christie J, Merrill JD, Althaus J, Schmidt K, Ballard PL, Ischiropoulos H, Ballard RA. Plasma 3-nitrotyrosine and outcome in neonates with severe bronchopulmonary dysplasia after inhaled nitric oxide. Free Radic Biol Med 2003;34:1146-1152.
24. Baier RJ, Majid A, Parupia H, Loggins J, Kruger TE. CC chemokine concentrations increase in respiratory distress syndrome and correlate with development of bronchopulmonary dysplasia. Pediatr Pulmonol 2004;37:137-148.
25. Wagenaar GT, ter Horst SA, van Gastelen MA, Leijser LM, Mauad T, van der Velden PA, de Heer E, Hiemstra PS, Poorthuis BJ, Walther FJ. Gene expression profile and histopathology of experimental bronchopulmonary dysplasia induced by prolonged oxidative stress. Free Radic Biol Med 2004;36:782-801.
26. Banks BA, Ischiropoulos H, McClelland M, Ballard PL, Ballard RA. Plasma 3-nitrotyrosine is elevated in premature infants who develop bronchopulmonary dysplasia. Pediatrics 1998;101:870-874.
27. Lorch SA, Foust R III, Gow A, Arkovitz M, Salzman AL, Szabo C, Vayert B, Geffard M, Ischiropoulos H. Immunohistochemical localization of protein 3-nitrotyrosine and S-nitrosocysteine in a murine model of inhaled nitric oxide therapy. Pediatr Res 2000;47:798-805.
28. Lorch SA, Munson D, Lightfoot RT, Ischiropoulos H. Oxygen tension and inhaled nitric oxide modulate pulmonary levels of S-nitrosocysteine and 3-nitrotyrosine in rats. Pediatr Res 2004;56:345-352.
29. Jankov RP, Johnstone L, Luo X, Robinson BH, Tanswell AK. Macrophages as a major source of oxygen radicals in the hyperoxic newborn rat lung. Free Radic Biol Med 2003;35:200-209.
30. Koeck T, Fu X, Hazen SL, Crabb JW, Stuehr DJ, Aulak KS. Rapid and selective oxygen-regulated protein tyrosine denitration and nitration in mitochondria. J Biol Chem 2004;279:27257-27262.
31. Kamisaki Y, Wada K, Bian K, Balabanli B, Davis K, Martin E, Behbod F, Lee YC, Murad F. An activity in rat tissues that modifies nitrotyrosine-containing proteins. Proc Natl Acad Sci USA 1998;95:11584-11589.
32. Stamler JS, Lamas S, Fang FC. Nitrosylation: the prototypic redox-based signaling mechanism. Cell 2001;106:675-683.
33. Black SM, Heidersbach RS, McMullan DM, Bekker JM, Johengen MJ, Fineman JR. Inhaled nitric oxide inhibits NOS activity in lambs: potential mechanism for rebound pulmonary hypertension. Am J Physiol 1999;277:H1849-H1856.
34. McMullan DM, Bekker JM, Johengen MJ, Hendricks-Munoz K, Gerrets R, Black SM, Fineman JR. Inhaled nitric oxide-induced rebound pulmonary hypertension: role for endothelin-1. Am J Physiol Heart Circ Physiol 2001;280:H777-H785.