Lung fluid transport in aquaporin-5 knockout mice

Journal of Clinical Investigation

Volumn 105, Issue 1, 2000, Pages 93-100

  Ma, Tonghui ^a   Fukuda, Norimasa ^a   Song, Yuanlin ^a   Matthay, Michael A ^a   Verkman, Alan S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AQUAPORIN; KERATINOCYTE GROWTH FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CAPILLARY PERMEABILITY; CONTROLLED STUDY; GENE DELETION; KNOCKOUT MOUSE; LUNG ALVEOLUS CELL TYPE 1; LUNG ARTERY PRESSURE; LUNG EDEMA; LUNG FLUID; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RESPIRATORY EPITHELIUM; SALIVATION; VASCULAR ENDOTHELIUM;

EID: 0033987856     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI8258     Document Type: Article

References (42)

1. Verkman, A.S. 1998. Water transporting mechanisms in airways and lung. In Pulmonary edema. M.A. Matthay and D. Ingbar, editors. Marcel Dekker Inc. New York, NY. 525-547.
2. Folkesson, H.G., Matthay, M.A. Hasegawa, H., Kheradmand, F., and Verkman, A.S. 1994. Transcellular water transport in lung alveolar epithelium through mercury-sensitive water channels. Proc. Natl. Acad. Sci. USA. 91:4970-4974.
3. Carter, E.P., Matthay, M.A., Farinas, J., and Verkman, A.S. 1996. Transalveolar osmotic and diffusional water permeability in intact mouse lung measured by a novel surface fluorescence method. J. Gen. Physiol. 108:133-142.
4. Carter, E.P., Umenishi, F., Matthay, M.A. and Verkman, A.S. 1997. Developmental changes in alveolar water permeability in perinatal rabbit lung. J. Clin. Invest. 100:1071-1078.
5. Dobbs, L., et al. 1998. Highly water-permeable type I alveolar epithelial cells confer high water permeability between the airspace and vasculature in rat lung. Proc. Natl. Acad. Sci. USA. 95:2991-2996.
6. Carter, E.P., Ölveczky, B.P., Matthay, M.A., and Verkman, A.S. 1998. High microvascular endothelial water permeability in mouse lung measured by a pleural surface fluorescence method. Biophys. J. 74:2121-2128.
7. Folkesson, H., Matthay, M., Frigeri, A., and Verkman, A.S. 1996. High transepithelial water permeability in microperfused distal airways: evidence for channel-mediated water transport. J. Clin. Invest. 97:664-671.
8. Matthay, M.A., Folkesson, H., and Verkman, A.S. 1996. Salt and water transport across alveolar and distal airway epithelia in the adult lung. Am. J. Physiol. 270:L487-L503.
9. Olver, R.E. 1994. Fluid secretion and absorption in the fetus. In Fluid and solute transport in the airspaces af the lung. R.M. Effros and H.K. Chang, editors. Marcel Dekker Inc. New York, NY. 281-302.
10. Nielsen, S., King, L.S., Christensen, B.M., and Agre, P. 1997. Aquaporins in complex tissues. II. Subcellular distribution in respiratory and glandular tissues of rat. Am J. Physiol. 273:C1549-C1561.
11. Hasegawa, H., Zhang, R., Dohrman, A., and Verkman, A.S. 1993. Tissue-specific expression of mRNA encoding the rat kidney water channel CHIP28k by in situ hybridisation. Am. J. Physiol. 264:C237-C245.
12. Effros, R.M., et al. 1997. Water transport and distribution of aquaporin-1 in the pulmonary airspaces. J. Appl. Physiol. 83:1002-1016.
13. Frigeri, A., Gropper, M., Turck, C.W., and Verkman, A.S. 1995. Immunolocalization of the mercurial-insensitive water channel and glycerol intrinsic protein in epithelial cell plasma membranes. Proc. Natl. Acad. Sci. USA. 92:4328-4331.
14. King, L.S., Nielsen, S., and Agre, P. 1997. Aquaporins in complex tissues. I. Developmental patterns in respiratory and glandular tissues of rat. Am. J. Physiol. 273:C1541-C1548.
15. Funaki, H., et al. 1998. Localization and expression of AQP5 in cornea, serous salivary glands, and pulmonary epithelial cells. Am. J. Physiol. 275:C1151-C1157.
16. Umenishi, F., et al. 1996. Sharp increase in rat lung water channel expression in the perinatal period. Am. J. Respir. Cell Mol. Biol. 15:673-679.
17. Yasui, M., et al. 1997. Perinatal changes in expression of aquaporin-4 and other water and ion transporters in rat lung J. Physiol. 505:3-11.
18. Ruddy, M.K., Drazen, J.M., Pitkanan, O.M., Rafii, B., and Harris, H.W. 1998. Modulation of aquaporin-4 and the amiloride-inhibitable sodium channel in perinatal rat lung epithelial cells. Am J. Physiol. 274:L1066-L1072.
19. King, L.S., Nielsen, S., and Agre, P. 1996. Aquaporin-1 water channel protein in lung. Ontogeny, steroid-induced expression, and distribution in rat. J. Clin. Invest. 97:2183-2191.
20. Borok, Z., et al. 1998. Keratinocyte growth factor modulates alveolar epithelial cell phenotype in vitro: expression of aquaporin 5. Am. J. Respir. Cell Mol Biol. 18:554-561.
21. Ma, T., et al. 1998. Severely impaired urinary concentrating ability in transgenic mice lacking aquaporin-1 water channels. J. Biol. Chem. 273:4296-4299.
22. Schnermann, J., Chou, J., Ma, T., Knepper, M.A., and Verkman, A.S. 1998. Detective proximal tubule reabsorption in transgenic aquaporin-1 null mice. Proc. Natl. Acad Sci. USA. 95:9660-9664.
23. Chou, C.L., et al. 1999. Reduced water permeability and altered ultrastructure in thin descending limb of Henle in aquaporin-1 null mice. J. Clin. Invest. 103:491-496.
24. Bai, C., et al. 1999. Lung fluid transport in aquaponn-1 and aquaporin-4 knockout mice. J Clin. Invest. 103:555-561.
25. Ma, T., et al. 1997. Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4. J. Clin. Invest. 100:957-962.
26. Chou, C.L. Ma, T., Yang, B., Knepper, M.A., and Verkman, A.S. 1998. Four-fold reduction in water permeability in inner medullary collecting duct of aquaporin-4 knockout mice. Am. J. Physiol. 274:C549-C554.
27. Manley, G.T., et al. 2000. Aquaporin-4 deletion in mice reduces brain edema following acute water intoxication and ischemic stroke. Nat. Medicine. In press.
28. Marsuzaki, T., Suzuki, T., Koyama, H., Tanaka, S., and Takara, K. 1999. Aquaporin-5 (AQP5), a water channel protein, in the rat salivary and lacrimal glands: immunolocalization and effect of secretory stimulation. Cell Tissue Res. 295:513-521.
29. Ma, T., et al. 1999. Defective secretion of saliva in transgenic mice lacking aquaporin-5 water channels. J. Biol. Chem. 274:20071-20074.
30. Spring, K.R. 1998. Routes and mechanism of fluid transport by epithelia. Annu. Rev. Physiol. 60:105-119.
31. Rezaiguia, S., et al. 1997. Acute bacterial pneumonia in rats increases alveolar epithelial fluid clearance by tumor necrosis facror-alpha-dependent mechanism. J. Clin. Invest. 99:325-335.
32. Wang, Y., Folkesson, H.G., Jayr. C., Ware, L.B., and Matthay, MA. 1999. Alveolar epithelial fluid transport can be simultaneously upregulated by both KGF and beta-agonist therapy. J. Appl. Physiol. 87:1852-1860.
33. Ulich, T.R., et al. 1994. Keratinocyte growth factor is a growth factor for type II pneumocytes in vivo. J. Clin. Invest. 93:1298-1306.
34. Stone, K.C., Mercer, R.R., Gehr, P., Stockstill, B., and Crapo, J.D. 1992. Distribution of cell numbers and volumes between alveolar and non-alveolar tissue. Am. J. Respir. Cell Mol. Biol. 6:235-243.
35. Ma, T., et al. 1999. Targeted gene deletion of aquaporin-3 in mice. J. Am. Soc. Nephrol. 10:19A.
36. Ishibashi, K., et al. 1998. Cloning and functional expression of a new aquaporin (AQP9) abundantly expressed in the peripheral leukocytes permeable to water and urea, but not glycerol. Biochem. Biophys. Res. Comm. 244:268-274.
37. Ko, S.B., et al. 1999. Cloning and functional expression of rAQP9L, a new member of aquaporin family from rat liver. Biochem. Mol. Biol. Int. 47:309-318.
38. Factor, P., et al. 1998. Augmentation of lung liquid clearance via adenovirus-mediated transfer of Na,K-ATPase subunit gene. J. Clin. Invest. 102:1421-1430.
39. Garat, C., Carter, H., and Matthay, M.A. 1998. New in situ mouse model to quantify alveolar epithelial fluid clearance. J. Appl. Physiol. 84:1763-1767.
40. Wangensteen, O.D. 1994. Nonselective solute transport across the pulmonary epithelium. In Fluid and solute transport in the airspaces of the lung. Volume 70. R.M. Effros and H.K. Chang., editors. 374-397.
41. Yang, B., and Verkman, A.S. 1997. Water and glycerol permeability of aquaporins 1-5 and MIP determined quantitatively by expression of epitopetagged constructs in Xenopus oocytes. J. Biol. Chem. 272:16140-16146.
42. Meinild, A.K., Klaerke, D.A., and Zeuthen, T. 1998. Bidirectional water fluxes and specificity for small hydrophilic molecules in aquaporins 0-5. J. Biol. Chem. 273:32446-32451.