메뉴 건너뛰기




Volumn 29, Issue 2, 2013, Pages 155-164

Regulation of the timing of oligodendrocyte differentiation: Mechanisms and perspectives

Author keywords

differentiation; oligodendrocytes; remyelination; timing

Indexed keywords

BETA CATENIN; CYCLIN DEPENDENT KINASE INHIBITOR; NOTCH RECEPTOR; PLATELET DERIVED GROWTH FACTOR; REGULATOR PROTEIN; THYROID HORMONE; TRANSCRIPTION FACTOR; WNT PROTEIN;

EID: 84877876303     PISSN: 16737067     EISSN: 19958218     Source Type: Journal    
DOI: 10.1007/s12264-013-1314-2     Document Type: Review
Times cited : (45)

References (78)
  • 1
    • 0033957316 scopus 로고    scopus 로고
    • A cell-intrinsic timer that operates during oligodendrocyte development
    • 10649292 10.1002/(SICI)1521-1878(200001)22:1<64: AID-BIES11>3.0. CO;2-Q 1:CAS:528:DC%2BD3MXmslGrsLo%3D
    • Durand B, Raff M. A cell-intrinsic timer that operates during oligodendrocyte development. Bioessays 2000, 22: 64-71.
    • (2000) Bioessays , vol.22 , pp. 64-71
    • Durand, B.1    Raff, M.2
  • 2
    • 0022468128 scopus 로고
    • Clonal analysis of oligodendrocyte development in culture: Evidence for a developmental clock that counts cell divisions
    • 3948247 10.1016/0092-8674(86)90843-3 1:STN:280:DyaL287jtlGksg%3D%3D
    • Temple S, Raff MC. Clonal analysis of oligodendrocyte development in culture: evidence for a developmental clock that counts cell divisions. Cell 1986, 44(5): 773-779.
    • (1986) Cell , vol.44 , Issue.5 , pp. 773-779
    • Temple, S.1    Raff, M.C.2
  • 3
    • 0031080329 scopus 로고    scopus 로고
    • Oligodendrocyte precursor cells count time but not cell divisions before differentiation
    • 9016704 10.1016/S0960-9822(06)00060-1 1:CAS:528:DyaK2sXhtlOju70%3D
    • Gao FB, Durand B, Raff M. Oligodendrocyte precursor cells count time but not cell divisions before differentiation. Curr Biol 1997, 7: 152-155.
    • (1997) Curr Biol , vol.7 , pp. 152-155
    • Gao, F.B.1    Durand, B.2    Raff, M.3
  • 4
    • 0031057796 scopus 로고    scopus 로고
    • Origins of spinal cord oligodendrocytes: Possible developmental and evolutionary relationships with motor neurons
    • 9078434 10.1159/000111186 1:CAS:528:DyaK2sXhvVaksbY%3D
    • Richardson WD, Pringle NP, Yu WP, Hall AC. Origins of spinal cord oligodendrocytes: possible developmental and evolutionary relationships with motor neurons. Dev Neurosci 1997, 19: 58-68.
    • (1997) Dev Neurosci , vol.19 , pp. 58-68
    • Richardson, W.D.1    Pringle, N.P.2    Yu, W.P.3    Hall, A.C.4
  • 5
    • 0037678463 scopus 로고    scopus 로고
    • Gli2 is required for normal Shh signaling and oligodendrocyte development in the spinal cord
    • 12837627 10.1016/S1044-7431(03)00067-8 1:CAS:528:DC%2BD3sXkvFGntrs%3D
    • Qi Y, Tan M, Hui CC, Qiu M. Gli2 is required for normal Shh signaling and oligodendrocyte development in the spinal cord. Mol Cell Neurosci 2003, 23: 440-450.
    • (2003) Mol Cell Neurosci , vol.23 , pp. 440-450
    • Qi, Y.1    Tan, M.2    Hui, C.C.3    Qiu, M.4
  • 6
    • 0347519179 scopus 로고    scopus 로고
    • Regionspecific and stage-dependent regulation of Olig gene expression and oligodendrogenesis by Nkx6.1 homeodomain transcription factor
    • 14602683 10.1242/dev.00868 1:CAS:528:DC%2BD2cXktF2r
    • Liu R, Cai J, Hu X, Tan M, Qi Y, German M, et al. Regionspecific and stage-dependent regulation of Olig gene expression and oligodendrogenesis by Nkx6.1 homeodomain transcription factor. Development 2003, 130: 6221-6231.
    • (2003) Development , vol.130 , pp. 6221-6231
    • Liu, R.1    Cai, J.2    Hu, X.3    Tan, M.4    Qi, Y.5    German, M.6
  • 7
    • 11344277387 scopus 로고    scopus 로고
    • Generation of oligodendrocyte precursor cells from mouse dorsal spinal cord independent of Nkx6 regulation and Shh signaling
    • 15629701 10.1016/j.neuron.2004.12.028 1:CAS:528:DC%2BD2MXmtl2ksQ%3D%3D
    • Cai J, Qi Y, Hu X, Tan M, Liu Z, Zhang J, et al. Generation of oligodendrocyte precursor cells from mouse dorsal spinal cord independent of Nkx6 regulation and Shh signaling. Neuron 2005, 45: 41-53.
    • (2005) Neuron , vol.45 , pp. 41-53
    • Cai, J.1    Qi, Y.2    Hu, X.3    Tan, M.4    Liu, Z.5    Zhang, J.6
  • 8
    • 77953796037 scopus 로고    scopus 로고
    • MicroRNAs are essential for the developmental switch from neurogenesis to gliogenesis in the developing spinal cord
    • 20554876 10.1523/JNEUROSCI.1169-10.2010 1:CAS:528:DC%2BC3cXot1Cqtb0%3D
    • Zheng K, Li H, Zhu Y, Zhu Q, Qiu M. MicroRNAs are essential for the developmental switch from neurogenesis to gliogenesis in the developing spinal cord. J Neurosci 2010, 30: 8245-8250.
    • (2010) J Neurosci , vol.30 , pp. 8245-8250
    • Zheng, K.1    Li, H.2    Zhu, Y.3    Zhu, Q.4    Qiu, M.5
  • 9
    • 0036569618 scopus 로고    scopus 로고
    • Posttranscriptional regulation of p18 and p27 Cdk inhibitor proteins and the timing of oligodendrocyte differentiation
    • 11969268 10.1006/dbio.2002.0626 1:CAS:528:DC%2BD38XjtVegu70%3D
    • Tokumoto YM, Apperly JA, Gao FB, Raff MC. Posttranscriptional regulation of p18 and p27 Cdk inhibitor proteins and the timing of oligodendrocyte differentiation. Dev Biol 2002, 245: 224-234.
    • (2002) Dev Biol , vol.245 , pp. 224-234
    • Tokumoto, Y.M.1    Apperly, J.A.2    Gao, F.B.3    Raff, M.C.4
  • 10
    • 0031026190 scopus 로고    scopus 로고
    • Accumulation of the cyclin-dependent kinase inhibitor p27/Kip1 and the timing of oligodendrocyte differentiation
    • 9029151 10.1093/emboj/16.2.306 1:CAS:528:DyaK2sXpvVOmtQ%3D%3D
    • Durand B, Gao FB, Raff M. Accumulation of the cyclin-dependent kinase inhibitor p27/Kip1 and the timing of oligodendrocyte differentiation. EMBO J 1997, 16: 306-317.
    • (1997) EMBO J , vol.16 , pp. 306-317
    • Durand, B.1    Gao, F.B.2    Raff, M.3
  • 11
    • 34250012532 scopus 로고    scopus 로고
    • A crucial role for p57(Kip2) in the intracellular timer that controls oligodendrocyte differentiation
    • 17553990 10.1523/JNEUROSCI.0628-07.2007 1:CAS:528:DC%2BD2sXmsl2isr0%3D
    • Dugas JC, Ibrahim A, Barres BA. A crucial role for p57(Kip2) in the intracellular timer that controls oligodendrocyte differentiation. J Neurosci 2007, 27: 6185-6196.
    • (2007) J Neurosci , vol.27 , pp. 6185-6196
    • Dugas, J.C.1    Ibrahim, A.2    Barres, B.A.3
  • 12
    • 0032857528 scopus 로고    scopus 로고
    • Loss of p27Kip1 function results in increased proliferative capacity of oligodendrocyte progenitors but unaltered timing of differentiation
    • 10457012 1:CAS:528:DyaK1MXmsleqsb4%3D
    • Casaccia-Bonnefil P, Hardy RJ, Teng KK, Levine JM, Koff A, Chao MV. Loss of p27Kip1 function results in increased proliferative capacity of oligodendrocyte progenitors but unaltered timing of differentiation. Development 1999, 126: 4027-4037.
    • (1999) Development , vol.126 , pp. 4027-4037
    • Casaccia-Bonnefil, P.1    Hardy, R.J.2    Teng, K.K.3    Levine, J.M.4    Koff, A.5    Chao, M.V.6
  • 13
    • 0033854551 scopus 로고    scopus 로고
    • Basic helix-loop-helix proteins and the timing of oligodendrocyte differentiation
    • 10862737 1:CAS:528:DC%2BD3cXlsFOrtbg%3D
    • Kondo T, Raff M. Basic helix-loop-helix proteins and the timing of oligodendrocyte differentiation. Development 2000, 127: 2989-2998.
    • (2000) Development , vol.127 , pp. 2989-2998
    • Kondo, T.1    Raff, M.2
  • 14
    • 0035052390 scopus 로고    scopus 로고
    • A role for the helix-loop-helix protein Id2 in the control of oligodendrocyte development
    • 11301021 10.1016/S0896-6273(01)00237-9 1:CAS:528:DC%2BD3MXis1Kjsbc%3D
    • Wang S, Sdrulla A, Johnson JE, Yokota Y, Barres BA. A role for the helix-loop-helix protein Id2 in the control of oligodendrocyte development. Neuron 2001, 29: 603-614.
    • (2001) Neuron , vol.29 , pp. 603-614
    • Wang, S.1    Sdrulla, A.2    Johnson, J.E.3    Yokota, Y.4    Barres, B.A.5
  • 15
    • 0034595233 scopus 로고    scopus 로고
    • The id4 HLH protein and the timing of oligodendrocyte differentiation
    • 10790366 10.1093/emboj/19.9.1998 1:CAS:528:DC%2BD3cXktFWiurk%3D
    • Kondo T, Raff M. The id4 HLH protein and the timing of oligodendrocyte differentiation. EMBO J 2000, 19: 1998-2007.
    • (2000) EMBO J , vol.19 , pp. 1998-2007
    • Kondo, T.1    Raff, M.2
  • 16
    • 33750447322 scopus 로고    scopus 로고
    • SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function
    • 17084361 10.1016/j.devcel.2006.08.011 1:CAS:528:DC%2BD28Xht1Smsr%2FE
    • Stolt CC, Schlierf A, Lommes P, Hillgartner S, Werner T, Kosian T, et al. SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Dev Cell 2006, 11: 697-709.
    • (2006) Dev Cell , vol.11 , pp. 697-709
    • Stolt, C.C.1    Schlierf, A.2    Lommes, P.3    Hillgartner, S.4    Werner, T.5    Kosian, T.6
  • 17
    • 0037080877 scopus 로고    scopus 로고
    • Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10
    • 11799060 10.1101/gad.215802 1:CAS:528:DC%2BD38Xos1ersQ%3D%3D
    • Stolt CC, Rehberg S, Ader M, Lommes P, Riethmacher D, Schachner M, et al. Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10. Genes Dev 2002, 16: 165-170.
    • (2002) Genes Dev , vol.16 , pp. 165-170
    • Stolt, C.C.1    Rehberg, S.2    Ader, M.3    Lommes, P.4    Riethmacher, D.5    Schachner, M.6
  • 18
    • 33749371515 scopus 로고    scopus 로고
    • An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation
    • 16908628 10.1242/dev.02522 1:CAS:528:DC%2BD28XhtV2hsLnK
    • Wang SZ, Dulin J, Wu H, Hurlock E, Lee SE, Jansson K, et al. An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation. Development 2006, 133: 3389-3398.
    • (2006) Development , vol.133 , pp. 3389-3398
    • Wang, S.Z.1    Dulin, J.2    Wu, H.3    Hurlock, E.4    Lee, S.E.5    Jansson, K.6
  • 19
    • 84863128025 scopus 로고    scopus 로고
    • Dualmode modulation of Smad signaling by Smad-interacting protein Sip1 is required for myelination in the central nervous system
    • 22365546 10.1016/j.neuron.2011.12.021 1:CAS:528:DC%2BC38XjtFSnu7o%3D
    • Weng Q, Chen Y, Wang H, Xu X, Yang B, He Q, et al. Dualmode modulation of Smad signaling by Smad-interacting protein Sip1 is required for myelination in the central nervous system. Neuron 2012, 73: 713-728.
    • (2012) Neuron , vol.73 , pp. 713-728
    • Weng, Q.1    Chen, Y.2    Wang, H.3    Xu, X.4    Yang, B.5    He, Q.6
  • 20
    • 67649667327 scopus 로고    scopus 로고
    • Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination
    • 19596243 10.1016/j.cell.2009.04.031 1:CAS:528:DC%2BD1MXps1ygu74%3D
    • Emery B, Agalliu D, Cahoy JD, Watkins TA, Dugas JC, Mulinyawe SB, et al. Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination. Cell 2009, 138: 172-185.
    • (2009) Cell , vol.138 , pp. 172-185
    • Emery, B.1    Agalliu, D.2    Cahoy, J.D.3    Watkins, T.A.4    Dugas, J.C.5    Mulinyawe, S.B.6
  • 21
    • 76149131010 scopus 로고    scopus 로고
    • ZFP191 is required by oligodendrocytes for CNS myelination
    • 20080941 10.1101/gad.1864510 1:CAS:528:DC%2BC3cXhsFeit70%3D
    • Howng SY, Avila RL, Emery B, Traka M, Lin W, Watkins T, et al. ZFP191 is required by oligodendrocytes for CNS myelination. Genes Dev 2010, 24: 301-311.
    • (2010) Genes Dev , vol.24 , pp. 301-311
    • Howng, S.Y.1    Avila, R.L.2    Emery, B.3    Traka, M.4    Lin, W.5    Watkins, T.6
  • 22
    • 0034914553 scopus 로고    scopus 로고
    • Control of oligodendrocyte differentiation by the Nkx2.2 homeodomain transcription factor
    • 11526078 1:CAS:528:DC%2BD3MXlslKqs7Y%3D
    • Qi Y, Cai J, Wu Y, Wu R, Lee J, Fu H, et al. Control of oligodendrocyte differentiation by the Nkx2.2 homeodomain transcription factor. Development 2001, 128: 2723-2733.
    • (2001) Development , vol.128 , pp. 2723-2733
    • Qi, Y.1    Cai, J.2    Wu, Y.3    Wu, R.4    Lee, J.5    Fu, H.6
  • 23
    • 33750213516 scopus 로고    scopus 로고
    • A molecular insight of Hes5-dependent inhibition of myelin gene expression: Old partners and new players
    • 17006542 10.1038/sj.emboj.7601352 1:CAS:528:DC%2BD28XhtVyktLfF
    • Liu A, Li J, Marin-Husstege M, Kageyama R, Fan Y, Gelinas C, et al. A molecular insight of Hes5-dependent inhibition of myelin gene expression: old partners and new players. EMBO J 2006, 25: 4833-4842.
    • (2006) EMBO J , vol.25 , pp. 4833-4842
    • Liu, A.1    Li, J.2    Marin-Husstege, M.3    Kageyama, R.4    Fan, Y.5    Gelinas, C.6
  • 24
    • 0037663384 scopus 로고    scopus 로고
    • The Sox9 transcription factor determines glial fate choice in the developing spinal cord
    • 12842915 10.1101/gad.259003 1:CAS:528:DC%2BD3sXlsV2ru7k%3D
    • Stolt CC, Lommes P, Sock E, Chaboissier MC, Schedl A, Wegner M. The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev 2003, 17: 1677-1689.
    • (2003) Genes Dev , vol.17 , pp. 1677-1689
    • Stolt, C.C.1    Lommes, P.2    Sock, E.3    Chaboissier, M.C.4    Schedl, A.5    Wegner, M.6
  • 25
    • 3042705838 scopus 로고    scopus 로고
    • Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy
    • 15102707 10.1242/dev.01114 1:CAS:528:DC%2BD2cXltlGrt7w%3D
    • Stolt CC, Lommes P, Friedrich RP, Wegner M. Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy. Development 2004, 131: 2349-2358.
    • (2004) Development , vol.131 , pp. 2349-2358
    • Stolt, C.C.1    Lommes, P.2    Friedrich, R.P.3    Wegner, M.4
  • 26
    • 40949084666 scopus 로고    scopus 로고
    • Sox9 and Sox10 influence survival and migration of oligodendrocyte precursors in the spinal cord by regulating PDGF receptor alpha expression
    • 18184726 10.1242/dev.010454 1:CAS:528:DC%2BD1cXjsFyhsLY%3D
    • Finzsch M, Stolt CC, Lommes P, Wegner M. Sox9 and Sox10 influence survival and migration of oligodendrocyte precursors in the spinal cord by regulating PDGF receptor alpha expression. Development 2008, 135: 637-646.
    • (2008) Development , vol.135 , pp. 637-646
    • Finzsch, M.1    Stolt, C.C.2    Lommes, P.3    Wegner, M.4
  • 27
    • 76549125423 scopus 로고    scopus 로고
    • Co-localization of Nkx6.2 and Nkx2.2 homeodomain proteins in differentiated myelinating oligodendrocytes
    • 19780200
    • Cai J, Zhu Q, Zheng K, Li H, Qi Y, Cao Q, et al. Co-localization of Nkx6.2 and Nkx2.2 homeodomain proteins in differentiated myelinating oligodendrocytes. Glia 2010, 58: 458-468.
    • (2010) Glia , vol.58 , pp. 458-468
    • Cai, J.1    Zhu, Q.2    Zheng, K.3    Li, H.4    Qi, Y.5    Cao, Q.6
  • 28
    • 80455173402 scopus 로고    scopus 로고
    • Nkx2.2 repressor complex regulates islet beta-cell specification and prevents beta-to-alpha-cell reprogramming
    • 22056672 10.1101/gad.173039.111 1:CAS:528:DC%2BC3MXhsFaktLzL
    • Papizan JB, Singer RA, Tschen SI, Dhawan S, Friel JM, Hipkens SB, et al. Nkx2.2 repressor complex regulates islet beta-cell specification and prevents beta-to-alpha-cell reprogramming. Genes Dev 2011, 25: 2291-2305.
    • (2011) Genes Dev , vol.25 , pp. 2291-2305
    • Papizan, J.B.1    Singer, R.A.2    Tschen, S.I.3    Dhawan, S.4    Friel, J.M.5    Hipkens, S.B.6
  • 29
    • 0035855787 scopus 로고    scopus 로고
    • The bHLH transcription factor olig2 promotes oligodendrocyte differentiation in collaboration with Nkx2.2
    • 11567617 10.1016/S0896-6273(01)00414-7 1:CAS:528:DC%2BD3MXnt1OqsLc%3D
    • Zhou Q, Choi G, Anderson DJ. The bHLH transcription factor olig2 promotes oligodendrocyte differentiation in collaboration with Nkx2.2. Neuron 2001, 31: 791-807.
    • (2001) Neuron , vol.31 , pp. 791-807
    • Zhou, Q.1    Choi, G.2    Anderson, D.J.3
  • 30
    • 0033764232 scopus 로고    scopus 로고
    • Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors
    • 10719889 10.1016/S0896-6273(00)80898-3 1:CAS:528:DC%2BD3cXhslOktrg%3D
    • Zhou Q, Wang S, Anderson DJ. Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors. Neuron 2000, 25: 331-343.
    • (2000) Neuron , vol.25 , pp. 331-343
    • Zhou, Q.1    Wang, S.2    Anderson, D.J.3
  • 31
    • 0037023492 scopus 로고    scopus 로고
    • The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification
    • 11955447 10.1016/S0092-8674(02)00677-3 1:CAS:528:DC%2BD38XjtVOntL8%3D
    • Zhou Q, Anderson DJ. The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification. Cell 2002, 109: 61-73.
    • (2002) Cell , vol.109 , pp. 61-73
    • Zhou, Q.1    Anderson, D.J.2
  • 32
    • 0037023529 scopus 로고    scopus 로고
    • Common developmental requirement for olig function indicates a motor neuron/oligodendrocyte connection
    • 11955448 10.1016/S0092-8674(02)00678-5 1:CAS:528:DC%2BD38XjtVOntLw%3D
    • Lu QR, Sun T, Zhu Z, Ma N, Garcia M, Stiles CD, et al. Common developmental requirement for olig function indicates a motor neuron/oligodendrocyte connection. Cell 2002, 109: 75-86.
    • (2002) Cell , vol.109 , pp. 75-86
    • Lu, Q.R.1    Sun, T.2    Zhu, Z.3    Ma, N.4    Garcia, M.5    Stiles, C.D.6
  • 33
    • 37549005215 scopus 로고    scopus 로고
    • Olig1 and Sox10 interact synergistically to drive myelin basic protein transcription in oligodendrocytes
    • 18160645 10.1523/JNEUROSCI.4456-07.2007 1:CAS:528:DC%2BD1cXktVGjuw%3D%3D
    • Li H, Lu Y, Smith HK, Richardson WD. Olig1 and Sox10 interact synergistically to drive myelin basic protein transcription in oligodendrocytes. J Neurosci 2007, 27: 14375-14382.
    • (2007) J Neurosci , vol.27 , pp. 14375-14382
    • Li, H.1    Lu, Y.2    Smith, H.K.3    Richardson, W.D.4
  • 34
    • 79955832426 scopus 로고    scopus 로고
    • Differential and cooperative actions of Olig1 and Olig2 transcription factors on immature proliferating cells after contusive spinal cord injury
    • 21538562 10.1002/glia.21182
    • Kim HM, Hwang DH, Choi JY, Park CH, Suh-Kim H, Kim SU, et al. Differential and cooperative actions of Olig1 and Olig2 transcription factors on immature proliferating cells after contusive spinal cord injury. Glia 2011, 59: 1094-1106.
    • (2011) Glia , vol.59 , pp. 1094-1106
    • Kim, H.M.1    Hwang, D.H.2    Choi, J.Y.3    Park, C.H.4    Suh-Kim, H.5    Kim, S.U.6
  • 35
    • 13844276513 scopus 로고    scopus 로고
    • Myelinogenesis and axonal recognition by oligodendrocytes in brain are uncoupled in Olig1-null mice
    • 15703389 10.1523/JNEUROSCI.3034-04.2005 1:CAS:528:DC%2BD2MXhs1Kmur0%3D
    • Xin M, Yue T, Ma Z, Wu FF, Gow A, Lu QR. Myelinogenesis and axonal recognition by oligodendrocytes in brain are uncoupled in Olig1-null mice. J Neurosci 2005, 25: 1354-1365.
    • (2005) J Neurosci , vol.25 , pp. 1354-1365
    • Xin, M.1    Yue, T.2    Ma, Z.3    Wu, F.F.4    Gow, A.5    Lu, Q.R.6
  • 36
    • 84864019723 scopus 로고    scopus 로고
    • Phosphorylated olig1 localizes to the cytosol of oligodendrocytes and promotes membrane expansion and maturation
    • 22639060 10.1002/glia.22364
    • Niu J, Mei F, Wang L, Liu S, Tian Y, Mo W, et al. Phosphorylated olig1 localizes to the cytosol of oligodendrocytes and promotes membrane expansion and maturation. Glia 2012, 60: 1427-1436.
    • (2012) Glia , vol.60 , pp. 1427-1436
    • Niu, J.1    Mei, F.2    Wang, L.3    Liu, S.4    Tian, Y.5    Mo, W.6
  • 37
    • 33745576853 scopus 로고    scopus 로고
    • Olig gene function in CNS development and disease
    • 16652341 10.1002/glia.20273
    • Ligon KL, Fancy SP, Franklin RJ, Rowitch DH. Olig gene function in CNS development and disease. Glia 2006, 54: 1-10.
    • (2006) Glia , vol.54 , pp. 1-10
    • Ligon, K.L.1    Fancy, S.P.2    Franklin, R.J.3    Rowitch, D.H.4
  • 38
    • 43049087027 scopus 로고    scopus 로고
    • Ascl1 is required for oligodendrocyte development in the spinal cord
    • 18287202 10.1242/dev.015370 1:CAS:528:DC%2BD1cXltlaitrs%3D
    • Sugimori M, Nagao M, Parras CM, Nakatani H, Lebel M, Guillemot F, et al. Ascl1 is required for oligodendrocyte development in the spinal cord. Development 2008, 135: 1271-1281.
    • (2008) Development , vol.135 , pp. 1271-1281
    • Sugimori, M.1    Nagao, M.2    Parras, C.M.3    Nakatani, H.4    Lebel, M.5    Guillemot, F.6
  • 39
    • 84865308707 scopus 로고    scopus 로고
    • The identification of transcriptional targets of Ascl1 in oligodendrocyte development
    • 22714260 10.1002/glia.22369
    • Ueno T, Ito J, Hoshikawa S, Ohori Y, Fujiwara S, Yamamoto S, et al. The identification of transcriptional targets of Ascl1 in oligodendrocyte development. Glia 2012, 60: 1495-1505.
    • (2012) Glia , vol.60 , pp. 1495-1505
    • Ueno, T.1    Ito, J.2    Hoshikawa, S.3    Ohori, Y.4    Fujiwara, S.5    Yamamoto, S.6
  • 40
    • 77958577154 scopus 로고    scopus 로고
    • Epigenetic modifiers are necessary but not sufficient for reprogramming non-myelinating cells into myelin gene-expressing cells
    • 20885955 10.1371/journal.pone.0013023
    • Liu J, Sandoval J, Doh ST, Cai L, Lopez-Rodas G, Casaccia P. Epigenetic modifiers are necessary but not sufficient for reprogramming non-myelinating cells into myelin gene-expressing cells. PLoS One 2010, 5(9): e13023.
    • (2010) PLoS One , vol.5 , Issue.9 , pp. 13023
    • Liu, J.1    Sandoval, J.2    Doh, S.T.3    Cai, L.4    Lopez-Rodas, G.5    Casaccia, P.6
  • 41
    • 67649797866 scopus 로고    scopus 로고
    • HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction
    • 19503085 10.1038/nn.2333 1:CAS:528:DC%2BD1MXntVWisbo%3D
    • Ye F, Chen Y, Hoang T, Montgomery RL, Zhao XH, Bu H, et al. HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat Neurosci 2009, 12: 829-838.
    • (2009) Nat Neurosci , vol.12 , pp. 829-838
    • Ye, F.1    Chen, Y.2    Hoang, T.3    Montgomery, R.L.4    Zhao, X.H.5    Bu, H.6
  • 42
    • 22344446199 scopus 로고    scopus 로고
    • Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain
    • 15897262 10.1083/jcb.200412101 1:CAS:528:DC%2BD2MXksFyqs7Y%3D
    • Shen S, Li J, Casaccia-Bonnefil P. Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain. J Cell Biol 2005, 169: 577-589.
    • (2005) J Cell Biol , vol.169 , pp. 577-589
    • Shen, S.1    Li, J.2    Casaccia-Bonnefil, P.3
  • 43
    • 84856748638 scopus 로고    scopus 로고
    • MicroRNAs and glial cell development
    • 21555783 10.1177/1073858411398322 1:CAS:528:DC%2BC38XmslCmtr4%3D
    • Zheng K, Li H, Huang H, Qiu M. MicroRNAs and glial cell development. Neuroscientist 2012, 18: 114-118.
    • (2012) Neuroscientist , vol.18 , pp. 114-118
    • Zheng, K.1    Li, H.2    Huang, H.3    Qiu, M.4
  • 44
    • 84862177776 scopus 로고    scopus 로고
    • Fine-tuning oligodendrocyte development by microRNAs
    • 22347159 10.3389/fnins.2012.00013 1:CAS:528:DC%2BC38XjsFyit74%3D
    • Barca-Mayo O, Lu QR. Fine-tuning oligodendrocyte development by microRNAs. Front Neurosci 2012, 6: 13.
    • (2012) Front Neurosci , vol.6 , pp. 13
    • Barca-Mayo, O.1    Lu, Q.R.2
  • 45
    • 77649175470 scopus 로고    scopus 로고
    • Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination
    • 20223197 10.1016/j.neuron.2010.01.027 1:CAS:528:DC%2BC3cXltlWku7c%3D
    • Dugas JC, Cuellar TL, Scholze A, Ason B, Ibrahim A, Emery B, et al. Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination. Neuron 2010, 65: 597-611.
    • (2010) Neuron , vol.65 , pp. 597-611
    • Dugas, J.C.1    Cuellar, T.L.2    Scholze, A.3    Ason, B.4    Ibrahim, A.5    Emery, B.6
  • 46
    • 77649166937 scopus 로고    scopus 로고
    • MicroRNA-mediated control of oligodendrocyte differentiation
    • 20223198 10.1016/j.neuron.2010.02.018 1:CAS:528:DC%2BC3cXltlWrsr4%3D
    • Zhao X, He X, Han X, Yu Y, Ye F, Chen Y, et al. MicroRNA-mediated control of oligodendrocyte differentiation. Neuron 2010, 65: 612-626.
    • (2010) Neuron , vol.65 , pp. 612-626
    • Zhao, X.1    He, X.2    Han, X.3    Yu, Y.4    Ye, F.5    Chen, Y.6
  • 47
    • 0024282594 scopus 로고
    • Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture
    • 3287177 10.1038/333562a0 1:CAS:528:DyaL1cXktlarsrw%3D
    • Raff MC, Lillien LE, Richardson WD, Burne JF, Noble MD. Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture. Nature 1988, 333: 562-565.
    • (1988) Nature , vol.333 , pp. 562-565
    • Raff, M.C.1    Lillien, L.E.2    Richardson, W.D.3    Burne, J.F.4    Noble, M.D.5
  • 48
    • 0024787406 scopus 로고
    • PDGF and intracellular signaling in the timing of oligodendrocyte differentiation
    • 2557355 10.1083/jcb.109.6.3411 1:CAS:528:DyaL1MXmt1GqsLY%3D
    • Hart IK, Richardson WD, Bolsover SR, Raff MC. PDGF and intracellular signaling in the timing of oligodendrocyte differentiation. J Cell Biol 1989, 109: 3411-3417.
    • (1989) J Cell Biol , vol.109 , pp. 3411-3417
    • Hart, I.K.1    Richardson, W.D.2    Bolsover, S.R.3    Raff, M.C.4
  • 49
    • 0032078122 scopus 로고    scopus 로고
    • Oligodendrocyte population dynamics and the role of PDGF in vivo
    • 9620692 10.1016/S0896-6273(00)80469-9 1:CAS:528:DyaK1cXjs1Sgt7s%3D
    • Calver AR, Hall AC, Yu WP, Walsh FS, Heath JK, Betsholtz C, et al. Oligodendrocyte population dynamics and the role of PDGF in vivo. Neuron 1998, 20: 869-882.
    • (1998) Neuron , vol.20 , pp. 869-882
    • Calver, A.R.1    Hall, A.C.2    Yu, W.P.3    Walsh, F.S.4    Heath, J.K.5    Betsholtz, C.6
  • 50
    • 0036333452 scopus 로고    scopus 로고
    • Dual origin of spinal oligodendrocyte progenitors and evidence for the cooperative role of Olig2 and Nkx2.2 in the control of oligodendrocyte differentiation
    • 11830569 1:CAS:528:DC%2BD38XitF2gu78%3D
    • Fu H, Qi Y, Tan M, Cai J, Takebayashi H, Nakafuku M, et al. Dual origin of spinal oligodendrocyte progenitors and evidence for the cooperative role of Olig2 and Nkx2.2 in the control of oligodendrocyte differentiation. Development 2002, 129: 681-693.
    • (2002) Development , vol.129 , pp. 681-693
    • Fu, H.1    Qi, Y.2    Tan, M.3    Cai, J.4    Takebayashi, H.5    Nakafuku, M.6
  • 51
    • 0028179013 scopus 로고
    • Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras
    • 8041791 10.1073/pnas.91.15.7335 1:CAS:528:DyaK2cXltVSltrc%3D
    • Bennett AM, Tang TL, Sugimoto S, Walsh CT, Neel BG. Protein-tyrosine- phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras. Proc Natl Acad Sci U S A 1994, 91: 7335-7339.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 7335-7339
    • Bennett, A.M.1    Tang, T.L.2    Sugimoto, S.3    Walsh, C.T.4    Neel, B.G.5
  • 52
    • 77956581492 scopus 로고    scopus 로고
    • Control of oligodendrocyte generation and proliferation by Shp2 protein tyrosine phosphatase
    • 20648636
    • Zhu Y, Park J, Hu X, Zheng K, Li H, Cao Q, et al. Control of oligodendrocyte generation and proliferation by Shp2 protein tyrosine phosphatase. Glia 2010, 58: 1407-1414.
    • (2010) Glia , vol.58 , pp. 1407-1414
    • Zhu, Y.1    Park, J.2    Hu, X.3    Zheng, K.4    Li, H.5    Cao, Q.6
  • 53
    • 78751509692 scopus 로고    scopus 로고
    • The ERK2 mitogen-activated protein kinase regulates the timing of oligodendrocyte differentiation
    • 21248107 10.1523/JNEUROSCI.3239-10.2011 1:CAS:528:DC%2BC3MXhsVemsbo%3D
    • Fyffe-Maricich SL, Karlo JC, Landreth GE, Miller RH. The ERK2 mitogen-activated protein kinase regulates the timing of oligodendrocyte differentiation. J Neurosci 2011, 31: 843-850.
    • (2011) J Neurosci , vol.31 , pp. 843-850
    • Fyffe-Maricich, S.L.1    Karlo, J.C.2    Landreth, G.E.3    Miller, R.H.4
  • 54
    • 0034963497 scopus 로고    scopus 로고
    • Role of thyroid hormone receptors in timing oligodendrocyte differentiation
    • 11412031 10.1006/dbio.2001.0293 1:CAS:528:DC%2BD3MXksVWqtrg%3D
    • Billon N, Tokumoto Y, Forrest D, Raff M. Role of thyroid hormone receptors in timing oligodendrocyte differentiation. Dev Biol 2001, 235: 110-120.
    • (2001) Dev Biol , vol.235 , pp. 110-120
    • Billon, N.1    Tokumoto, Y.2    Forrest, D.3    Raff, M.4
  • 55
    • 0030602033 scopus 로고    scopus 로고
    • Evidence for the existence of at least two timing mechanisms that contribute to oligodendrocyte generation in vitro
    • 8948570 10.1006/dbio.1996.0280 1:CAS:528:DyaK28XntlSqsr0%3D
    • Ibarrola N, Mayer-Proschel M, Rodriguez-Pena A, Noble M. Evidence for the existence of at least two timing mechanisms that contribute to oligodendrocyte generation in vitro. Dev Biol 1996, 180: 1-21.
    • (1996) Dev Biol , vol.180 , pp. 1-21
    • Ibarrola, N.1    Mayer-Proschel, M.2    Rodriguez-Pena, A.3    Noble, M.4
  • 56
    • 0037011105 scopus 로고    scopus 로고
    • Normal timing of oligodendrocyte development depends on thyroid hormone receptor alpha 1 (TRalpha1)
    • 12456652 10.1093/emboj/cdf662 1:CAS:528:DC%2BD38XpsFChurk%3D
    • Billon N, Jolicoeur C, Tokumoto Y, Vennstrom B, Raff M. Normal timing of oligodendrocyte development depends on thyroid hormone receptor alpha 1 (TRalpha1). EMBO J 2002, 21: 6452-6460.
    • (2002) EMBO J , vol.21 , pp. 6452-6460
    • Billon, N.1    Jolicoeur, C.2    Tokumoto, Y.3    Vennstrom, B.4    Raff, M.5
  • 57
    • 0037022565 scopus 로고    scopus 로고
    • Persistence of oligodendrocyte precursor cells and altered myelination in optic nerve associated to retina degeneration in mice devoid of all thyroid hormone receptors
    • 11867729 10.1073/pnas.052482299 1:CAS:528:DC%2BD38Xit1Crtbg%3D
    • Baas D, Legrand C, Samarut J, Flamant F. Persistence of oligodendrocyte precursor cells and altered myelination in optic nerve associated to retina degeneration in mice devoid of all thyroid hormone receptors. Proc Natl Acad Sci U S A 2002, 99: 2907-2911.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 2907-2911
    • Baas, D.1    Legrand, C.2    Samarut, J.3    Flamant, F.4
  • 58
    • 0032126751 scopus 로고    scopus 로고
    • Notch receptor activation inhibits oligodendrocyte differentiation
    • 9697852 10.1016/S0896-6273(00)80515-2
    • Wang S, Sdrulla AD, diSibio G, Bush G, Nofziger D, Hicks C, et al. Notch receptor activation inhibits oligodendrocyte differentiation. Neuron 1998, 21: 63-75.
    • (1998) Neuron , vol.21 , pp. 63-75
    • Wang, S.1    Sdrulla, A.D.2    Disibio, G.3    Bush, G.4    Nofziger, D.5    Hicks, C.6
  • 59
    • 0036469825 scopus 로고    scopus 로고
    • Central nervous system myelination in mice with deficient expression of Notch1 receptor
    • 11813235 10.1002/jnr.10128 1:CAS:528:DC%2BD38Xht1Oms7o%3D
    • Givogri MI, Costa RM, Schonmann V, Silva AJ, Campagnoni AT, Bongarzone ER. Central nervous system myelination in mice with deficient expression of Notch1 receptor. J Neurosci Res 2002, 67: 309-320.
    • (2002) J Neurosci Res , vol.67 , pp. 309-320
    • Givogri, M.I.1    Costa, R.M.2    Schonmann, V.3    Silva, A.J.4    Campagnoni, A.T.5    Bongarzone, E.R.6
  • 60
    • 0037135989 scopus 로고    scopus 로고
    • Notch1 control of oligodendrocyte differentiation in the spinal cord
    • 12186854 10.1083/jcb.200202002 1:CAS:528:DC%2BD38XmsVSnurw%3D
    • Genoud S, Lappe-Siefke C, Goebbels S, Radtke F, Aguet M, Scherer SS, et al. Notch1 control of oligodendrocyte differentiation in the spinal cord. J Cell Biol 2002, 158: 709-718.
    • (2002) J Cell Biol , vol.158 , pp. 709-718
    • Genoud, S.1    Lappe-Siefke, C.2    Goebbels, S.3    Radtke, F.4    Aguet, M.5    Scherer, S.S.6
  • 61
    • 73149124029 scopus 로고    scopus 로고
    • Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination
    • 19855010 10.1073/pnas.0902834106 1:CAS:528:DC%2BD1MXhsFGlsbfP
    • Zhang Y, Argaw AT, Gurfein BT, Zameer A, Snyder BJ, Ge C, et al. Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination. Proc Natl Acad Sci U S A 2009, 106: 19162-19167.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 19162-19167
    • Zhang, Y.1    Argaw, A.T.2    Gurfein, B.T.3    Zameer, A.4    Snyder, B.J.5    Ge, C.6
  • 62
    • 67649655942 scopus 로고    scopus 로고
    • Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS
    • 19515974 10.1101/gad.1806309 1:CAS:528:DC%2BD1MXos1GitLc%3D
    • Fancy SP, Baranzini SE, Zhao C, Yuk DI, Irvine KA, Kaing S, et al. Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS. Genes Dev 2009, 23: 1571-1585.
    • (2009) Genes Dev , vol.23 , pp. 1571-1585
    • Fancy, S.P.1    Baranzini, S.E.2    Zhao, C.3    Yuk, D.I.4    Irvine, K.A.5    Kaing, S.6
  • 63
    • 84859907605 scopus 로고    scopus 로고
    • Tcf7l2 is tightly controlled during myelin formation
    • 22160878 10.1007/s10571-011-9778-y 1:CAS:528:DC%2BC38XkvVCnsbY%3D
    • Fu H, Kesari S, Cai J. Tcf7l2 is tightly controlled during myelin formation. Cell Mol Neurobiol 2012, 32: 345-352.
    • (2012) Cell Mol Neurobiol , vol.32 , pp. 345-352
    • Fu, H.1    Kesari, S.2    Cai, J.3
  • 64
    • 69249203776 scopus 로고    scopus 로고
    • Wnt signaling is sufficient to perturb oligodendrocyte maturation
    • 19619658 10.1016/j.mcn.2009.07.010 1:CAS:528:DC%2BD1MXhtVKkt7nE
    • Feigenson K, Reid M, See J, Crenshaw EB 3rd, Grinspan JB. Wnt signaling is sufficient to perturb oligodendrocyte maturation. Mol Cell Neurosci 2009, 42: 255-265.
    • (2009) Mol Cell Neurosci , vol.42 , pp. 255-265
    • Feigenson, K.1    Reid, M.2    See, J.3    Crenshaw III, E.B.4    Grinspan, J.B.5
  • 65
    • 74449091354 scopus 로고    scopus 로고
    • The oligodendrocyte-specific G protein-coupled receptor GPR17 is a cell-intrinsic timer of myelination
    • 19838178 10.1038/nn.2410 1:CAS:528:DC%2BD1MXht1OgsrrI
    • Chen Y, Wu H, Wang S, Koito H, Li J, Ye F, et al. The oligodendrocyte-specific G protein-coupled receptor GPR17 is a cell-intrinsic timer of myelination. Nat Neurosci 2009, 12: 1398-1406.
    • (2009) Nat Neurosci , vol.12 , pp. 1398-1406
    • Chen, Y.1    Wu, H.2    Wang, S.3    Koito, H.4    Li, J.5    Ye, F.6
  • 66
    • 56349145808 scopus 로고    scopus 로고
    • The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair
    • 18974869 10.1371/journal.pone.0003579
    • Lecca D, Trincavelli ML, Gelosa P, Sironi L, Ciana P, Fumagalli M, et al. The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair. PLoS One 2008, 3: e3579.
    • (2008) PLoS One , vol.3 , pp. 3579
    • Lecca, D.1    Trincavelli, M.L.2    Gelosa, P.3    Sironi, L.4    Ciana, P.5    Fumagalli, M.6
  • 67
    • 84862667140 scopus 로고    scopus 로고
    • LINGO-1, a transmembrane signaling protein, inhibits oligodendrocyte differentiation and myelination through intercellular self-interactions
    • 22514275 10.1074/jbc.M112.366179 1:CAS:528:DC%2BC38XptVWrurk%3D
    • Jepson S, Vought B, Gross CH, Gan L, Austen D, Frantz JD, et al. LINGO-1, a transmembrane signaling protein, inhibits oligodendrocyte differentiation and myelination through intercellular self-interactions. J Biol Chem 2012, 287: 22184-22195.
    • (2012) J Biol Chem , vol.287 , pp. 22184-22195
    • Jepson, S.1    Vought, B.2    Gross, C.H.3    Gan, L.4    Austen, D.5    Frantz, J.D.6
  • 68
    • 22844453047 scopus 로고    scopus 로고
    • LINGO-1 negatively regulates myelination by oligodendrocytes
    • 15895088 10.1038/nn1460 1:CAS:528:DC%2BD2MXksVeitrg%3D
    • Mi S, Miller RH, Lee X, Scott ML, Shulag-Morskaya S, Shao Z, et al. LINGO-1 negatively regulates myelination by oligodendrocytes. Nat Neurosci 2005, 8: 745-751.
    • (2005) Nat Neurosci , vol.8 , pp. 745-751
    • Mi, S.1    Miller, R.H.2    Lee, X.3    Scott, M.L.4    Shulag-Morskaya, S.5    Shao, Z.6
  • 69
    • 34948888764 scopus 로고    scopus 로고
    • LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MoG-induced experimental autoimmune encephalomyelitis
    • 17906634 10.1038/nm1664 1:CAS:528:DC%2BD2sXhtFagsbzJ
    • Mi S, Hu B, Hahm K, Luo Y, Kam Hui ES, Yuan Q, et al. LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MoG-induced experimental autoimmune encephalomyelitis. Nat Med 2007, 13: 1228-1233.
    • (2007) Nat Med , vol.13 , pp. 1228-1233
    • Mi, S.1    Hu, B.2    Hahm, K.3    Luo, Y.4    Kam Hui, E.S.5    Yuan, Q.6
  • 70
    • 37349055151 scopus 로고    scopus 로고
    • Bone morphogenetic protein signaling and olig1/2 interact to regulate the differentiation and maturation of adult oligodendrocyte precursor cells
    • 17872503 10.1634/stemcells.2007-0284 1:CAS:528:DC%2BD1cXnvFCktA%3D%3D
    • Cheng X, Wang Y, He Q, Qiu M, Whittemore SR, Cao Q. Bone morphogenetic protein signaling and olig1/2 interact to regulate the differentiation and maturation of adult oligodendrocyte precursor cells. Stem Cells 2007, 25: 3204-3214.
    • (2007) Stem Cells , vol.25 , pp. 3204-3214
    • Cheng, X.1    Wang, Y.2    He, Q.3    Qiu, M.4    Whittemore, S.R.5    Cao, Q.6
  • 71
    • 4644223417 scopus 로고    scopus 로고
    • Interactions between ID and OLIG proteins mediate the inhibitory effects of BMP4 on oligodendroglial differentiation
    • 15280210 10.1242/dev.01273 1:CAS:528:DC%2BD2cXotVyjurY%3D
    • Samanta J, Kessler JA. Interactions between ID and OLIG proteins mediate the inhibitory effects of BMP4 on oligodendroglial differentiation. Development 2004, 131: 4131-4142.
    • (2004) Development , vol.131 , pp. 4131-4142
    • Samanta, J.1    Kessler, J.A.2
  • 72
    • 34447503745 scopus 로고    scopus 로고
    • BMPR1a signaling determines numbers of oligodendrocytes and calbindin-expressing interneurons in the cortex
    • 17626200 10.1523/JNEUROSCI.1434-07.2007 1:CAS:528:DC%2BD2sXnvFyhtbY%3D
    • Samanta J, Burke GM, McGuire T, Pisarek AJ, Mukhopadhyay A, Mishina Y, et al. BMPR1a signaling determines numbers of oligodendrocytes and calbindin-expressing interneurons in the cortex. J Neurosci 2007, 27: 7397-7407.
    • (2007) J Neurosci , vol.27 , pp. 7397-7407
    • Samanta, J.1    Burke, G.M.2    McGuire, T.3    Pisarek, A.J.4    Mukhopadhyay, A.5    Mishina, Y.6
  • 73
    • 34247360821 scopus 로고    scopus 로고
    • BMP signaling mutant mice exhibit glial cell maturation defects
    • 17391983 10.1016/j.mcn.2007.02.012 1:CAS:528:DC%2BD2sXkslCnsbw%3D
    • See J, Mamontov P, Ahn K, Wine-Lee L, Crenshaw EB, 3rd, Grinspan JB. BMP signaling mutant mice exhibit glial cell maturation defects. Mol Cell Neurosci 2007, 35: 171-182.
    • (2007) Mol Cell Neurosci , vol.35 , pp. 171-182
    • See, J.1    Mamontov, P.2    Ahn, K.3    Wine-Lee, L.4    Crenshaw III, E.B.5    Grinspan, J.B.6
  • 74
    • 38149129457 scopus 로고    scopus 로고
    • A transcriptome database for astrocytes, neurons, and oligodendrocytes: A new resource for understanding brain development and function
    • 18171944 10.1523/JNEUROSCI.4178-07.2008 1:CAS:528:DC%2BD1cXmtV2ltw%3D%3D
    • Cahoy JD, Emery B, Kaushal A, Foo LC, Zamanian JL, Christopherson KS, et al. A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function. J Neurosci 2008, 28: 264-278.
    • (2008) J Neurosci , vol.28 , pp. 264-278
    • Cahoy, J.D.1    Emery, B.2    Kaushal, A.3    Foo, L.C.4    Zamanian, J.L.5    Christopherson, K.S.6
  • 75
    • 0032763125 scopus 로고    scopus 로고
    • Activation and proliferation of endogenous oligodendrocyte precursor cells during ethidium bromide-induced demyelination
    • 10619551 10.1006/exnr.1999.7224 1:CAS:528:DC%2BD3cXjtVSgtA%3D%3D
    • Levine JM, Reynolds R. Activation and proliferation of endogenous oligodendrocyte precursor cells during ethidium bromide-induced demyelination. Exp Neurol 1999, 160: 333-347.
    • (1999) Exp Neurol , vol.160 , pp. 333-347
    • Levine, J.M.1    Reynolds, R.2
  • 76
    • 0034281366 scopus 로고    scopus 로고
    • NG2-positive oligodendrocyte progenitor cells in adult human brain and multiple sclerosis lesions
    • 10964946 1:CAS:528:DC%2BD3cXmsVyhurc%3D
    • Chang A, Nishiyama A, Peterson J, Prineas J, Trapp BD. NG2-positive oligodendrocyte progenitor cells in adult human brain and multiple sclerosis lesions. J Neurosci 2000, 20: 6404-6412.
    • (2000) J Neurosci , vol.20 , pp. 6404-6412
    • Chang, A.1    Nishiyama, A.2    Peterson, J.3    Prineas, J.4    Trapp, B.D.5
  • 77
    • 0031797815 scopus 로고    scopus 로고
    • Oligodendrocyte progenitors are present in the normal adult human CNS and in the lesions of multiple sclerosis
    • 9874475 10.1093/brain/121.12.2221
    • Scolding N, Franklin R, Stevens S, Heldin CH, Compston A, Newcombe J. Oligodendrocyte progenitors are present in the normal adult human CNS and in the lesions of multiple sclerosis. Brain 1998, 121 (Pt 12): 2221-2228.
    • (1998) Brain , vol.121 , Issue.PART 12 , pp. 2221-2228
    • Scolding, N.1    Franklin, R.2    Stevens, S.3    Heldin, C.H.4    Compston, A.5    Newcombe, J.6
  • 78
    • 0036720034 scopus 로고    scopus 로고
    • Why does remyelination fail in multiple sclerosis?
    • 12209119 10.1038/nrn917 1:CAS:528:DC%2BD38Xmslagsrk%3D
    • Franklin RJ. Why does remyelination fail in multiple sclerosis? Nat Rev Neurosci 2002, 3: 705-714.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 705-714
    • Franklin, R.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.