Multiple adaptive mechanisms affect asparagine synthetase substrate availability in asparaginase-resistant MOLT-4 human leukaemia cells

Biochemical Journal

Volumn 358, Issue 1, 2001, Pages 59-67

  Aslanian, A M ^a   Kilberg, M S ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Acute lymphoblastic leukaemia; Glutamine; Membrane transport

Indexed keywords

AMINO ACIDS; CELLS; CHEMOTHERAPY; DRUG PRODUCTS; TUMORS;

ENZYMATIC ACTIVITIES;

ENZYMES;

AMINO ACID; ASPARAGINASE; ASPARAGINE; ASPARTATE AMMONIA LIGASE; ASPARTIC ACID; GLUTAMINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADAPTATION; AMINO ACID TRANSPORT; ARTICLE; CANCER RECURRENCE; CANCER REGRESSION; CELL POPULATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LEUKEMIA CELL; METABOLISM; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINO ACIDS; ASPARAGINASE; ASPARTATE-AMMONIA LIGASE; ASPARTIC ACID; BIOLOGICAL TRANSPORT; CELL DIVISION; CELL MEMBRANE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE; FLOW CYTOMETRY; GLUTAMATE-AMMONIA LIGASE; GLUTAMINE; HUMANS; LEUKEMIA, LYMPHOCYTIC, ACUTE; RNA; RNA, MESSENGER; SUBSTRATE SPECIFICITY; TUMOR CELLS, CULTURED;

EID: 0035881515     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3580059     Document Type: Article

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