-
1
-
-
0034284267
-
Weekly polyethylene glycol conjugated L-asparaginase compared with biweekly dosing produces superior induction remission rates in childhood relapsed acute lymphoblastic leukemia: A Pediatric Oncology Group Study
-
Abshire TC, Pollock BH, Billett AL, et al. 2000. Weekly polyethylene glycol conjugated L-asparaginase compared with biweekly dosing produces superior induction remission rates in childhood relapsed acute lymphoblastic leukemia: a Pediatric Oncology Group Study. Blood, 96:1709-15.
-
(2000)
Blood
, vol.96
, pp. 1709-1715
-
-
Abshire, T.C.1
Pollock, B.H.2
Billett, A.L.3
-
2
-
-
0035672697
-
Comparison of intramuscular therapy with Erwinia asparaginase and asparaginase Medac: Pharmacokinetics, pharmacodynamics, formation of antibodies and influence on the coagulation system
-
Albertsen BK, Schroder H, Ingerslev J, et al. 2001. Comparison of intramuscular therapy with Erwinia asparaginase and asparaginase Medac: pharmacokinetics, pharmacodynamics, formation of antibodies and influence on the coagulation system. Br J Haematol, 115:983-90.
-
(2001)
Br J Haematol
, vol.115
, pp. 983-990
-
-
Albertsen, B.K.1
Schroder, H.2
Ingerslev, J.3
-
3
-
-
0036255941
-
Antibody formation during intravenous and intramuscular therapy with Erwinia asparaginase
-
Albertsen BK, Schroder H, Jakobsen P, et al. 2002. Antibody formation during intravenous and intramuscular therapy with Erwinia asparaginase. Med Pediatr Oncol, 38:310-16.
-
(2002)
Med Pediatr Oncol
, vol.38
, pp. 310-316
-
-
Albertsen, B.K.1
Schroder, H.2
Jakobsen, P.3
-
4
-
-
0242475199
-
Lack of asparagine depletion in the cerebrospinal fluid after one intravenous dose of PEG-asparaginase: A window study at initial diagnosis of childhood ALL
-
Appel IM, Pinheiro JP, den Boer ML, et al. 2003. Lack of asparagine depletion in the cerebrospinal fluid after one intravenous dose of PEG-asparaginase: a window study at initial diagnosis of childhood ALL. Leukemia, 17:2254-6.
-
(2003)
Leukemia
, vol.17
, pp. 2254-2256
-
-
Appel, I.M.1
Pinheiro, J.P.2
den Boer, M.L.3
-
5
-
-
0027197614
-
Comparative pharmacokinetic studies of three asparaginase preparations
-
Asselin BL, Whitin JC, Coppola DJ, et al. 1993. Comparative pharmacokinetic studies of three asparaginase preparations. J Clin Oncol, 11:1780-6.
-
(1993)
J Clin Oncol
, vol.11
, pp. 1780-1786
-
-
Asselin, B.L.1
Whitin, J.C.2
Coppola, D.J.3
-
6
-
-
0024355064
-
Pharmacodynamics, DNA Methylation studies and clinical response of high-dose 1-ß-D-arabinofuranosylcytosine before and after in vivo 5-azacytidine treatment in pediatric patients with refractory acute leukemia
-
Avramis VI, Mecum RA, Nyce J, et al. 1989. Pharmacodynamics, DNA Methylation studies and clinical response of high-dose 1-ß-D-arabinofuranosylcytosine before and after in vivo 5-azacytidine treatment in pediatric patients with refractory acute leukemia. Cancer Chemother Pharmacol, 24:203-10.
-
(1989)
Cancer Chemother Pharmacol
, vol.24
, pp. 203-210
-
-
Avramis, V.I.1
Mecum, R.A.2
Nyce, J.3
-
7
-
-
18644364984
-
Pharmacokinetic-pharmacodynamic relationships of asparaginase formulations: The past, the present and recommendations for the future
-
Avramis VI, Panosyan EH. 2005. Pharmacokinetic-pharmacodynamic relationships of asparaginase formulations: the past, the present and recommendations for the future. J Clin Pharmacokinetics, 44:367-93.
-
(2005)
J Clin Pharmacokinetics
, vol.44
, pp. 367-393
-
-
Avramis, V.I.1
Panosyan, E.H.2
-
8
-
-
0037085747
-
A randomized comparison of native Escherichia coli asparaginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed standard-risk acute lymphoblastic leukemia: A Children's Cancer Group study
-
Avramis VI, Sencer S, Periclou AP, et al. 2002. A randomized comparison of native Escherichia coli asparaginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed standard-risk acute lymphoblastic leukemia: a Children's Cancer Group study. Blood, 99:1986-94.
-
(2002)
Blood
, vol.99
, pp. 1986-1994
-
-
Avramis, V.I.1
Sencer, S.2
Periclou, A.P.3
-
9
-
-
36949081498
-
Evidence that the L-asparaginase activity of guinea pig serum is responsible for its anti-lymphoma effects
-
Broome JD. 1961. Evidence that the L-asparaginase activity of guinea pig serum is responsible for its anti-lymphoma effects. Nature, 191:1114-1115.
-
(1961)
Nature
, vol.191
, pp. 1114-1115
-
-
Broome, J.D.1
-
10
-
-
75449142384
-
Evidence that the L-asparaginase activity of guinea pig serum is responsible for its anti-lymphoma effects. I. Properties of the L-asparaginase of guinea pig serum in relation to those of the anti-lymphoma substance
-
Broome JD. 1963. Evidence that the L-asparaginase activity of guinea pig serum is responsible for its anti-lymphoma effects. I. Properties of the L-asparaginase of guinea pig serum in relation to those of the anti-lymphoma substance. J Exptl Med, 118:99-120.
-
(1963)
J Exptl Med
, vol.118
, pp. 99-120
-
-
Broome, J.D.1
-
11
-
-
0013837631
-
Antilymphoma activity of L-asparaginase in vivo: Clearance rate of enzyme preparations from guinea pig serum and yeast in relation to their effects on tumor growth
-
Broome JD. 1965. Antilymphoma activity of L-asparaginase in vivo: clearance rate of enzyme preparations from guinea pig serum and yeast in relation to their effects on tumor growth. J Natl Cancer Inst, 35:967-74.
-
(1965)
J Natl Cancer Inst
, vol.35
, pp. 967-974
-
-
Broome, J.D.1
-
12
-
-
0019737171
-
L-asparaginase: Discovery and development as a tumor-inhibitory agent
-
Broome JD. 1981. L-asparaginase: Discovery and development as a tumor-inhibitory agent. Cancer Treat Rep, 65:111-14.
-
(1981)
Cancer Treat Rep
, vol.65
, pp. 111-114
-
-
Broome, J.D.1
-
13
-
-
0014736182
-
Clinical evaluation of L-asparaginase
-
Burchenal JH, Karnofsky DA. 1970. Clinical evaluation of L-asparaginase. Cancer. 25:241-3.
-
(1970)
Cancer
, vol.25
, pp. 241-243
-
-
Burchenal, J.H.1
Karnofsky, D.A.2
-
14
-
-
0027414441
-
Asparaginase revisited
-
Capizzi RL. 1993. Asparaginase revisited. Leuk Lymphoma, 10(Suppl):147-50.
-
(1993)
Leuk Lymphoma
, vol.10
, Issue.SUPPL.
, pp. 147-150
-
-
Capizzi, R.L.1
-
15
-
-
0002528220
-
Asparaginases
-
In Holland JF (ed), Philadelphia, PA: Lea, Febiger
-
Capizzi RL, Holcenberg JS. 1993. Asparaginases. In Holland JF (ed). Cancer Medicine. Philadelphia, PA: Lea, Febiger. p 796-805.
-
(1993)
Cancer Medicine
, pp. 796-805
-
-
Capizzi, R.L.1
Holcenberg, J.S.2
-
16
-
-
0013504958
-
Enzyme therapy: L-asparaginase
-
In Chabner BA, Longo DL (eds), 2nd ed. Philadelphia, PA: Lippincott-Raven Publishers. Chapter 20
-
Chabner BA, Loo TL. 1996. Enzyme therapy: L-asparaginase. In Chabner BA, Longo DL (eds). Cancer chemotherapy and biotherapy, principles and practice. 2nd ed. Philadelphia, PA: Lippincott-Raven Publishers. Chapter 20, p 485-92.
-
(1996)
Cancer Chemotherapy and Biotherapy, Principles and Practice
, pp. 485-492
-
-
Chabner, B.A.1
Loo, T.L.2
-
17
-
-
0018704340
-
Effective dose of L-asparaginase for induction of remission in previously treated children with acute lymphocytic leukemia: A report from Childrens Cancer Study Group
-
Ertel IJ, Nesbit ME, Hammond D, et al. 1979. Effective dose of L-asparaginase for induction of remission in previously treated children with acute lymphocytic leukemia: a report from Childrens Cancer Study Group. Cancer Res, 39:3893-6.
-
(1979)
Cancer Res
, vol.39
, pp. 3893-3896
-
-
Ertel, I.J.1
Nesbit, M.E.2
Hammond, D.3
-
18
-
-
33644798329
-
Childhood acute lymphoblastic leukaemia and relapse
-
Gaynon PS. 2005. Childhood acute lymphoblastic leukaemia and relapse. Br J Haematol, 131:579-87.
-
(2005)
Br J Haematol
, vol.131
, pp. 579-587
-
-
Gaynon, P.S.1
-
19
-
-
0016425747
-
Nutritional effects on precursor uptake and compartmentalization of intracellular pools in relation to RNA synthesis
-
Goody HE, Ellem KA.1975. Nutritional effects on precursor uptake and compartmentalization of intracellular pools in relation to RNA synthesis. Biochim Biophys Acta, 383:30-9.
-
(1975)
Biochim Biophys Acta
, vol.383
, pp. 30-39
-
-
Goody, H.E.1
Ellem, K.A.2
-
20
-
-
4143063669
-
Asparaginase Pharmacokinetics following intensive polyethylene glycol conjugated L-asparaginase (PEG-ASNase) therapy for children with relapsed acute lymphoblastic leukemia
-
Hawkins DS, Park JR, Thomson BG, et al. 2004. Asparaginase Pharmacokinetics following intensive polyethylene glycol conjugated L-asparaginase (PEG-ASNase) therapy for children with relapsed acute lymphoblastic leukemia. Clin Cancer Res, 10:5335-41.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5335-5341
-
-
Hawkins, D.S.1
Park, J.R.2
Thomson, B.G.3
-
21
-
-
0017090511
-
Physical properties of antitumor glutaminase-asparaginase from Pseudomonas 7A
-
Holcenberg JS, Teller DC. 1976. Physical properties of antitumor glutaminase-asparaginase from Pseudomonas 7A. J Biol Chem, 251:5375-80.
-
(1976)
J Biol Chem
, vol.251
, pp. 5375-5380
-
-
Holcenberg, J.S.1
Teller, D.C.2
-
22
-
-
3943088431
-
Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML
-
Jamieson CH, Ailles LE, Dylla SJ, et al. 2004. Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML. N Engl J Med, 351:657-67.
-
(2004)
N Engl J Med
, vol.351
, pp. 657-667
-
-
Jamieson, C.H.1
Ailles, L.E.2
Dylla, S.J.3
-
23
-
-
33745765204
-
Asparagine depletion after pegylated E. Coli asparaginase treatment and induction outcome in children with acute lymphoblastic leukemia in first bone marrow relapse: A Children's Cancer Group study (CCG-1941)
-
Jarrar M, Gaynon PS, Periclou AP, et al. 2006. Asparagine depletion after pegylated E. Coli asparaginase treatment and induction outcome in children with acute lymphoblastic leukemia in first bone marrow relapse: A Children's Cancer Group study (CCG-1941). Pediatr Blood Cancer, 47:141-6.
-
(2006)
Pediatr Blood Cancer
, vol.47
, pp. 141-146
-
-
Jarrar, M.1
Gaynon, P.S.2
Periclou, A.P.3
-
24
-
-
0014986202
-
Atopic hypersensitivity to L-asparaginase. Resistance to immunosuppression
-
Khan A, Hill JM. 1971. Atopic hypersensitivity to L-asparaginase. Resistance to immunosuppression. Int Arch Allergy Appl Immunol, 40:463-9.
-
(1971)
Int Arch Allergy Appl Immunol
, vol.40
, pp. 463-469
-
-
Khan, A.1
Hill, J.M.2
-
25
-
-
84965111634
-
Regression of transplanted lymphomas induced in vivo by means of normal guinea pig serum. I. Course of transplanted cancers of various kinds in mice and rats given guinea pig serum, horse serum or rabbit serum
-
Kidd JG. 1953. Regression of transplanted lymphomas induced in vivo by means of normal guinea pig serum. I. Course of transplanted cancers of various kinds in mice and rats given guinea pig serum, horse serum or rabbit serum. J Exptl Med, 98:565-82.
-
(1953)
J Exptl Med
, vol.98
, pp. 565-582
-
-
Kidd, J.G.1
-
26
-
-
0036351278
-
Anti-Erwinia asparaginase antibodies during treatment of childhood acute lymphoblastic leukemia and their relationship to outcome: A case-control study
-
Klug-Albertsen B, Schmiegelow K, Schroder H, et al. 2002. Anti-Erwinia asparaginase antibodies during treatment of childhood acute lymphoblastic leukemia and their relationship to outcome: a case-control study. Cancer Chemother Pharmacol, 50:117-20.
-
(2002)
Cancer Chemother Pharmacol
, vol.50
, pp. 117-120
-
-
Klug-Albertsen, B.1
Schmiegelow, K.2
Schroder, H.3
-
28
-
-
0029833162
-
Crystal structure and amino acid sequence of Wolinella succinogenes L-asparaginase
-
Lubkowski J, Palm GJ, Gilliland GL, et al. 1996. Crystal structure and amino acid sequence of Wolinella succinogenes L-asparaginase. Eur J Biochem, 241:201-7.
-
(1996)
Eur J Biochem
, vol.241
, pp. 201-207
-
-
Lubkowski, J.1
Palm, G.J.2
Gilliland, G.L.3
-
29
-
-
30344481113
-
Imatinib binding and cKIT inhibition is abrogated by the cKIT kinase domain I missense mutation Val654Ala
-
McLean SR, Gana-Weisz M, Hartzoulakis B, et al. 2005. Imatinib binding and cKIT inhibition is abrogated by the cKIT kinase domain I missense mutation Val654Ala. Mol Cancer Ther, 4:2008-15.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 2008-2015
-
-
McLean, S.R.1
Gana-Weisz, M.2
Hartzoulakis, B.3
-
30
-
-
50549191387
-
Tumor inhibitory effect of L-asparaginase from Escherichia coli
-
Mashburn LT, Wriston JC. 1964. Tumor inhibitory effect of L-asparaginase from Escherichia coli. Arch Biocem, 105:451-2.
-
(1964)
Arch Biocem
, vol.105
, pp. 451-452
-
-
Mashburn, L.T.1
Wriston, J.C.2
-
31
-
-
0015954850
-
L-Glutamine as a substrate for L-asparaginase from Serratia marcescens
-
Novak EK, Philips AW. 1974. L-Glutamine as a substrate for L-asparaginase from Serratia marcescens. J Bacteriol, 117:593-600.
-
(1974)
J Bacteriol
, vol.117
, pp. 593-600
-
-
Novak, E.K.1
Philips, A.W.2
-
32
-
-
0014169820
-
Inhibition of leukemias in man by L-asparaginase
-
Oettgen HF, Old LJ, Boyse HA, et al. 1967. Inhibition of leukemias in man by L-asparaginase. Cancer Res, 27:2619-31.
-
(1967)
Cancer Res
, vol.27
, pp. 2619-2631
-
-
Oettgen, H.F.1
Old, L.J.2
Boyse, H.A.3
-
33
-
-
2442528894
-
Deamination of glutamine is a prerequisite for optimal asparagine deamination by asparaginases in vivo (CCG-1961)
-
Panosyan EH, Grigorian RS, Avramis IA, et al. 2004. Deamination of glutamine is a prerequisite for optimal asparagine deamination by asparaginases in vivo (CCG-1961). Anticancer Res, 24:1121-6.
-
(2004)
Anticancer Res
, vol.24
, pp. 1121-1126
-
-
Panosyan, E.H.1
Grigorian, R.S.2
Avramis, I.A.3
-
34
-
-
18644382427
-
Glutamine (Gln) deamination by asparaginases (ASNases) in children with higher risk acute lymphoblastic leukemia (HR ALL), (CCG-1961 study) [abstract]
-
Panosyan E, Avramis IA, Seibel NL, et al. 2002. Glutamine (Gln) deamination by asparaginases (ASNases) in children with higher risk acute lymphoblastic leukemia (HR ALL), (CCG-1961 study) [abstract]. Blood, 100:759a, nr 3006.
-
(2002)
Blood
, vol.100
, Issue.3006
-
-
Panosyan, E.1
Avramis, I.A.2
Seibel, N.L.3
-
35
-
-
32944481786
-
Risk of adverse events after completion of therapy for childhood acute lymphoblastic leukemia
-
Pui CH, Pei D, Sandlund JT, et al. 2005. Risk of adverse events after completion of therapy for childhood acute lymphoblastic leukemia. J Clin Oncol, 23:7936-41.
-
(2005)
J Clin Oncol
, vol.23
, pp. 7936-7941
-
-
Pui, C.H.1
Pei, D.2
Sandlund, J.T.3
-
36
-
-
29244492252
-
Therapy of chronic lymphocytic leukaemia with purine nucleoside analogues: Facts and controversies
-
Robak T. 2005. Therapy of chronic lymphocytic leukaemia with purine nucleoside analogues: facts and controversies. Drugs Aging, 22:983-1012.
-
(2005)
Drugs Aging
, vol.22
, pp. 983-1012
-
-
Robak, T.1
-
38
-
-
26944473293
-
Isolated testicular relapse in acute lymphoblastic leukemia-effective treatment with the modified CCG-112 protocol
-
Shama G, Bhagwat R, Pai SK, et al. 2005. Isolated testicular relapse in acute lymphoblastic leukemia-effective treatment with the modified CCG-112 protocol. Indian J Cancer, 42:65-9.
-
(2005)
Indian J Cancer
, vol.42
, pp. 65-69
-
-
Shama, G.1
Bhagwat, R.2
Pai, S.K.3
-
39
-
-
0035283163
-
Improved outcome for children with acute lymphoblastic leukemia: Results of Dana-Farber Consortium Protocol 91-01
-
Silverman LB, Gelber RD, Dalton VK, et al. 2001. Improved outcome for children with acute lymphoblastic leukemia: results of Dana-Farber Consortium Protocol 91-01. Blood, 97:1211-18.
-
(2001)
Blood
, vol.97
, pp. 1211-1218
-
-
Silverman, L.B.1
Gelber, R.D.2
Dalton, V.K.3
-
40
-
-
0000594688
-
A metabolic difference between two lines of lymphoma 6C3HED cells in relation to asparagine
-
Sobin LH, Kidd JG. 1965. A metabolic difference between two lines of lymphoma 6C3HED cells in relation to asparagine. Proc Soc Exp Biol Med, 119:325-7.
-
(1965)
Proc Soc Exp Biol Med
, vol.119
, pp. 325-327
-
-
Sobin, L.H.1
Kidd, J.G.2
-
41
-
-
0013881529
-
The incorporation of l-asparagine-14C by lymphoma 6C3HED cells: Its inhibition by guinea pig serum
-
Sobin LH, Kidd JG. 1966a. The incorporation of l-asparagine-14C by lymphoma 6C3HED cells: its inhibition by guinea pig serum. Cancer Res, 26:208-11.
-
(1966)
Cancer Res
, vol.26
, pp. 208-211
-
-
Sobin, L.H.1
Kidd, J.G.2
-
42
-
-
0013860751
-
Alterations in protein and nucleic acid metabolism of lymphoma 6C3HED-og cells in mice given guinea pig serum
-
Sobin LH, Kidd JG. 1966b. Alterations in protein and nucleic acid metabolism of lymphoma 6C3HED-og cells in mice given guinea pig serum. J Exp Med, 123:55-74.
-
(1966)
J Exp Med
, vol.123
, pp. 55-74
-
-
Sobin, L.H.1
Kidd, J.G.2
-
43
-
-
0017255588
-
Physical properties of L-asparaginase from Serratia marcescens
-
Stern ML, Phillips AW, Gottlieb AJ. 1976. Physical properties of L-asparaginase from Serratia marcescens. J Bacteriol, 125:719-27).
-
(1976)
J Bacteriol
, vol.125
, pp. 719-727
-
-
Stern, M.L.1
Phillips, A.W.2
Gottlieb, A.J.3
-
44
-
-
0014403969
-
A new L-asparaginase with anti-tumor activity
-
Wade HE, Elsworth R, Herbert D, et al. 1968. A new L-asparaginase with anti-tumor activity. Lancet, 2:776-7.
-
(1968)
Lancet
, vol.2
, pp. 776-777
-
-
Wade, H.E.1
Elsworth, R.2
Herbert, D.3
-
45
-
-
0020336534
-
Hypersensitivity reactions to cancer chemotherapy
-
Weiss RB. 1982. Hypersensitivity reactions to cancer chemotherapy. Semin Oncol, 9:5-12.
-
(1982)
Semin Oncol
, vol.9
, pp. 5-12
-
-
Weiss, R.B.1
|