Graft and diblock copolymer multifunctional micelles for cancer chemotherapy and imaging

Biomaterials

Volumn 31, Issue 8, 2010, Pages 2293-2301

  Tsai, Hsieh Chih ^a   Chang, Wei Hsiang ^a   Lo, Chun Liang ^c   Tsai, Cheng Hung ^a   Chang, Che Hau ^a   Ou, Ta Wei ^d   Yen, Tzu Chen ^e   Hsiue, Ging Ho ^a,b  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b CHUNG YUAN CHRISTIAN UNIVERSITY   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d NATIONAL CENTRAL UNIVERSITY   (Taiwan)

^e CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

AVERAGE DIAMETER; BINDING EFFECTS; BIODISTRIBUTIONS; CANCER CHEMOTHERAPY; CANCER-TARGETING; CELLULAR UPTAKE; CORE SHELL STRUCTURE; CYTOTOXIC EFFECTS; DIBLOCK COPOLYMER; DOXORUBICIN; FUNCTIONAL MOIETIES; HELA CELL LINE; IN-VIVO; INNER CORE; INTRACELLULAR DRUG DELIVERY; MIXED MICELLES; OUTER SHELLS; POLYMER CHAINS; SELF-ASSEMBLED; TEM; TUMOR GROWTH;

BLOCK COPOLYMERS; CELL CULTURE; CELL MEMBRANES; CHEMOTHERAPY; COPOLYMERIZATION; DRUG DELIVERY; FUNCTIONAL POLYMERS; GRAFTING (CHEMICAL); MICELLES; PHOSPHATASES; POLYETHYLENE OXIDES;

POLYETHYLENE GLYCOLS;

2 HYDROXYETHYL METHACRYLATE; COPOLYMER; DOXORUBICIN; FOLIC ACID; HISTIDINE; MACROGOL; NANOSPHERE; POLYLACTIC ACID; POLYMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CHEMOTHERAPY; CANCER GROWTH; CELL MEMBRANE; CONTROLLED STUDY; DIAGNOSTIC TEST; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG MECHANISM; DRUG RELEASE; DRUG TARGETING; DRUG UPTAKE; FEMALE; HELA CELL; HUMAN; HUMAN CELL; IMAGING SYSTEM; MALIGNANT NEOPLASTIC DISEASE; MEMBRANE BINDING; MICELLE; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BIOCOMPATIBLE MATERIALS; DOXORUBICIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FOLIC ACID; HELA CELLS; HUMANS; MICE; MICELLES; MOLECULAR STRUCTURE; NEOPLASM TRANSPLANTATION; NEOPLASMS; POLYMERS; TISSUE DISTRIBUTION;

EID: 74449084896     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.11.059     Document Type: Article

References (30)

1. Low P.S., and Antony A.C. Folate receptor-targeted drugs for cancer and inflammatory diseases. Adv Drug Deliv Rev 56 (2002) 1055-1058
2. Allen T.M. Ligand-targeted therapeutics in anticancer therapy. Nat Rev Drug Discov 2 (2002) 750-763
3. Nasongkla N., Shuai X., Ai H., Weinberg B.D., Pink J., Boothman D.A., et al. cRGDfunctionalized polymer micelles for targeted doxorubicin delivery. Angew Chem Int Ed 43 (2004) 6323-6327
4. Bertin P.A., Gibbs J.M., Shen C.K.F., Thaxton C.S., Russin W.A., Mirkin C.A., et al. Multifunctional polymeric nanoparticles from diverse bioactive agents. J Am Chem Soc 128 (2006) 4168-4169
5. Torchilin V.P., Lukyanov A.N., Gao Z.G., and Papahadjopoulos-Sternberg B. Immunomicelles: targeted pharmaceutical carriers for poorly soluble drugs. Proc Natl Acad Sci U S A 100 (2003) 6039-6044
6. Sethurame V.A., and Bae Y.H. TAT peptide-based micelle system for potential active targeting anti-cancer agents to acidic solid tumors. J Control Release 118 (2007) 216-224
7. Ross J.F., Chaudhuri P.K., and Ratnam M. Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell linesphysiologicand clinical implications. Cancer 73 (1994) 2432-2443
8. Russell-Jones G., McTavish K., McEwan J., Rice J., and Nowotnik D. Vitamin-mediated targeting as a potential mechanism to increase drug uptake by tumours. J Inorg Biochem 98 (2004) 1625-1633
9. Bae Y., Jang W.D., Nishiyama N., Fukushima S., and Kataoka K. Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery. Mol Biosystems 1 (2005) 242-250
10. Prabaharan M., Grailer J.J., Pilla S., Steeber D.A., and Gong S. Folate-conjugated amphiphilic hyperbranched block copolymers basedon Boltorn (R) H40, poly(l-lactide) and poly(ethylene glycol) for tumor targeted drug delivery. Biomaterials 30 (2009) 3009-3019
11. Sega E.I., and Low P.S. Tumor detection using folate receptor targeted imaging agent. Cancer Metastasis Rev 27 (2008) 655-664
12. Hong G., Yuan R., Liang B., Shen J., Yamg X., and Shuai X. Foltae-Functionalized polymeric micelles as hepatic carcinoma-targeted, MRI-ultrasensitive delivery system of anticancer drugs. Biomed Microdevices 10 (2008) 693-700
13. Zhang Z.P., Lee S.H., and Feng S.S. Folate-decorated poly(lactide-co-glycolide)-vitamin E TPGS nanoparticles for targeted drug delivery. Biomaterials 28 (2007) 1889-1899
14. Bae Y., Nishiyama N., and Kataoka K. In vivo antitumor activity of the folate-conjugated pH-sensitive polymeric micelle selectively releasing adriamycin in the intracellular acidic compartments. Bioconjug Chem 18 (2007) 1131-1139
15. Lo C.L., Huang C.K., Lin K.M., and Hsiue G.H. Self-Assembly of a micelle structure from graft and diblock copolymers: an example of overcoming the limitations of polyions in drug delivery. Adv Funct Mat 16 (2006) 2309-2316
16. Huang C.K., Lo C.L., Chen H.H., and Hsiue G.H. Multifunctional micelles for cancer cell targeting, distribution imaging, and anticancer drug delivery. Adv Funct Mat 17 (2007) 2291-2297
17. Lo C.L., Huang C.K., Lin K.M., and Hsiue G.H. Mixed micelles formed from graft and diblock copolymers for application in intracellular drug delivery. Biomaterials 28 (2007) 1225-1235
18. Lee E.S., Shin H.J., Na K., and Bae Y.H. Poly(l-histidine)-PEG block copolymer micelles and pH-induced destabilization. J Control Release 90 (2003) 363-374
19. Lee E.S., Na K., and Bae Y.H. Polymeric micelle for tumor pH and folate-mediated targeting. J Control Release 91 (2003) 103-113
20. Tsuruta T. Contemporary topic in polymeric materials for biomedical application. Adv Polym Sci 126 (1996) 1-51
21. Antonsen K.P., Bohnert J.L., Nabeshima Y., Sheu M., Wu X.S., and Hoffman A.S. Controlled release of protein from 2-hydroxyethyl methacrylate copolymer gels. Biomater Artif Cells Immobilization Biotechnol 21 (1993) 1-22
22. Dube D., Francis M., Leroux J.C., and Winnik F.M. Preparation and tumor cell uptake of poly(N-isopropylacrylamide) folate conjugates. Bioconjug Chem 13 (2002) 685-692
23. Kohori F., Yokoyama M., Sakai K., and Okano T. Process design for efficient and controlled drug incorporation into polymeric micelles carrier system. J Control Release 78 (2002) 155-163
24. Hobbs S.K., Monsky W.L., Yuan F., Roberts W.G., Griffith L., Torchilin V.P., et al. Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment. Proc Natl Acad Sci U S A 95 (1998) 4607-4612
25. Ogura H., Yoshinouchi M., Kudo T., Imura M., Fujiwara T., and Yabe Y. Human parillomavirus type-18 DNA in so-called HEP-2-cells, KB-cells and FL-cells further evidence that these cells are HeLa-cell derivative. Cell Mol Biol 39 (1993) 463-467
26. Elwood P.C. Molecular-cloning and characterization of the human folate-binding protein CDNA from placenta and malignant tissue culture(KB) cells. J Biol Chem 264 (1989) 14893-14901
27. Moghimi S.M., Hunter A.C., and Murray J.C. Long-circulating and target-specific nanoparticles: theory to practice. Pharmacol Rev 53 (2001) 283-318
28. Zeidán Q., Strauss M., Porras N., and Anselmi G. Differential long-term subcellular responses in heart and liver to adriamycin stress. Exogenous l-carnitine cardiac and hepatic protection. J Submicrosc Cytol Pathol 34 (2002) 315-321
29. Di D.A., Ghiggeri G.M., Di D.M., Jivotenko E., Acinni R., Campolo J., et al. Lysyl oxidase expression and collagen cross-linking during chronic adriamycin nephropathy. Nephron 76 (1997) 192-200
30. Singal P.K., Deally C.M., and Weinberg L.E. Subcellular effects of adriamycin in the heart: a concise review. J Mol Cell Cardiol 19 (1987) 817-828