Triptolide induces suppressor of cytokine signaling-3 expression and promotes lamina propria mononuclear cells apoptosis in Crohn's colitis

International Immunopharmacology

Volumn 16, Issue 2, 2013, Pages 268-274

  Li, Yi ^a   Tian, Yun ^b   Zhu, Weiming ^a   Gong, Jianfeng ^a   Zhang, Wei ^a   Yu, Chao ^c   Gu, Lili ^a   Li, Ning ^a   Li, Jieshou ^a  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^c Department of Plastic Surgery   (China)

Author keywords

Apoptosis; Crohn's disease; SOCS3; Triptolide

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 6; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRIPTOLIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CROHN DISEASE; DRUG EFFECT; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; LAMINA PROPRIA; MONONUCLEAR CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; BCL-X PROTEIN; CELLS, CULTURED; COLON; CROHN DISEASE; DITERPENES; EPOXY COMPOUNDS; FEMALE; HUMANS; INTERLEUKIN-10; LEUKOCYTES, MONONUCLEAR; MALE; MICE; MICE, INBRED C3H; MICE, TRANSGENIC; MUCOUS MEMBRANE; PHENANTHRENES; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA POLYMERASE II; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 84877839906     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2013.04.018     Document Type: Article

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