Triptolide suppresses IL-1β-induced chemokine and stromelysin-1 gene expression in human colonic subepithelial myofibroblasts

Acta Pharmacologica Sinica

Volumn 28, Issue 1, 2007, Pages 81-88

  Tao, Qing Song ^a   Ren, Jian An ^a   Li, Jie Shou ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Chemokine; Matrix metallopro teinase; Myofibroblast; Triptolide

Indexed keywords

CHEMOKINE; DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; STROMELYSIN; TRIPTOLIDE;

ARTICLE; CELL CULTURE; CELL STIMULATION; COLON MUCOSA; COLORECTAL CARCINOMA; CONTROLLED STUDY; DNA BINDING; DOSE RESPONSE; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; GASTRECTOMY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; MYOFIBROBLAST; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BLOTTING, WESTERN; CELLS, CULTURED; CHEMOKINE CCL2; CHEMOKINES; COLON; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPOXY COMPOUNDS; FIBROBLASTS; GENE EXPRESSION; HUMANS; I-KAPPA B PROTEINS; INTERLEUKIN-1BETA; INTERLEUKIN-8; MATRIX METALLOPROTEINASE 3; NF-KAPPA B; PHENANTHRENES; PHOSPHORYLATION; PLANTS, MEDICINAL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRIPTERYGIUM;

EID: 33846003478     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2006.00482.x     Document Type: Article

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