HMGB1 Accelerates Alveolar Epithelial Repair via an IL-1β- and αvβ6 Integrin-dependent Activation of TGF-β1

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Pittet, Jean François ^a   Koh, Hidefumi ^b   Fang, Xiaohui ^e   Iles, Karen ^a   Christiaans, Sarah ^a   Anjun, Naseem ^a   Wagener, Brant M ^a   Park, Dae Won ^c,d   Zmijewski, Jaroslaw W ^c   Matthay, Michael A ^e   Roux, Jérémie ^f  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c University of Alabama at Birmingham   (United States)

^d Korea University College of Medicine   (South Korea)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHAVBETA6 INTEGRIN; CHEMOKINE RECEPTOR CXCR4; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; STROMAL CELL DERIVED FACTOR 1; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA1;

ACUTE LUNG INJURY; ANIMAL CELL; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIZATION; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; MONOLAYER CULTURE; NONHUMAN; PROTEIN FUNCTION; RAT; SUPERNATANT; WOUND CLOSURE;

ANIMALS; ANTIGENS, NEOPLASM; CELLS, CULTURED; EPITHELIAL CELLS; HMGB1 PROTEIN; HUMANS; INTEGRINS; INTERLEUKIN-1BETA; PULMONARY ALVEOLI; RATS; TRANSFORMING GROWTH FACTOR BETA1; WOUND HEALING;

EID: 84877793729     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0063907     Document Type: Article

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