Interleukin-1β augments in vitro alveolar epithelial repair

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 279, Issue 6 23-6, 2000, Pages

  Geiser, Thomas ^a,b   Jarreau, Pierre Henri ^a   Atabai, Kamran ^a   Matthay, Michael A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

Alveolar type II epithelial cells; Epidermal growth factor; Transforming growth factor ; Wound repair

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ANTIBODY; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GENISTEIN; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR ALPHA; TYRPHOSTIN; ENZYME INHIBITOR; FLAVONOID; INTERLEUKIN 1;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CELL REGENERATION; CELL SPREADING; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; IN VITRO STUDY; LUNG ALVEOLUS CELL TYPE 2; LUNG ALVEOLUS EPITHELIUM; LUNG INJURY; MALE; MONOLAYER CULTURE; NONHUMAN; PRIORITY JOURNAL; RAT; WOUND HEALING; ADULT RESPIRATORY DISTRESS SYNDROME; ANIMAL; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; EPITHELIUM CELL; GERMFREE ANIMAL; LUNG ALVEOLUS; METABOLISM; PATHOLOGY; PHYSIOLOGY; RESPIRATORY TRACT MUCOSA; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; ENZYME INHIBITORS; EPIDERMAL GROWTH FACTOR; EPITHELIAL CELLS; FLAVONOIDS; INTERLEUKIN-1; MALE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; PULMONARY ALVEOLI; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, EPIDERMAL GROWTH FACTOR; RESPIRATORY DISTRESS SYNDROME, ADULT; RESPIRATORY MUCOSA; SPECIFIC PATHOGEN-FREE ORGANISMS; TRANSFORMING GROWTH FACTOR ALPHA; WOUND HEALING;

EID: 0034533248     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2000.279.6.l1184     Document Type: Article

References (33)

1. The type 2 cell as progenitor of alveolar epithelial regeneration. A cytodynamic study in mice after exposure to oxygen
2. Alterations of the gas exchange apparatus in adult respiratory insufficiency associated with septicemia
3. Soluble transforming growth factor-alpha is present in the pulmonary edema fluid of patients with acute lung injury
4. Extracellular regulation of interleukin (IL)-1beta through lung epithelial cells and defective IL-1 type II receptor expression
5. Kinetics of cytokine expression during healing of acute colitis in mice
6. Biologic basis for interleukin-1 in disease
7. An improved method for isolating type II cells in high yield and purity
8. Turnover of fibronectin and laminin by alveolar epithelial cells
9. Soluble and insoluble fibronectin increases alveolar epithelial wound healing in vitro
10. Cytokine-stimulated alveolar macrophages modulate alveolar epithelial repair
11. Rapid mitogen-activated protein kinase activation by transforming growth factor alpha in wounded rat intestinal epithelial cells
12. Inflammatory cytokines in patients with persistence of the acute respiratory distress syndrome
13. Differential regulation of pro-inflammatory cytokines during wound healing in normal and glucocorticoid-treated mice
14. Elerated interleukin-1 release by human alveolar macrophages during the adult respiratory distress syndrome
15. Transforming growth factor-α enhances alveolar epithelial cell repair in a new in vitro model
16. Integrin mediation of alveolar epithelial cell migration on fibronectin and type I collagen
17. Expression of transforming growth factor-alpha and epidermal growth factor receptor is increased following bleomycin-induced tung injury in rats
18. Elevated transforming growth factor-alpha levels in bronchoalveolar lavage fluid of patients with acute respiratory distress syndrome
19. Function of the alveolar epithelial barrier under pathologic conditions
20. Persistent elevation of inflammatory cytokines predicts a poor outcome in ARDS. Plasma IL-1beta and IL-6 levels are consistent and efficient predictors of outcome over time
21. The epidermal growth factor receptor network in type 2 pneumocytes exposed to hyperoxia in vitro
22. Induction of mitogen-activated protein kinase signal transduction pathway during gastric ulcer healing in rats
23. Proinflammatory activity in bronchoalveolar lavage fluids from patients with ARDS, a prominent role for interleukin-1
24. The alveolar space is the site of intense inflammatory and profibrotic reactions in the early phase of acute respiratory distress syndrome
25. Wound macrophages express TGF-alpha and other growth factors in vivo: Analysis by RNA phenotyping
26. Macrophage involvement in wound repair, remodeling, and fibrosis
27. Interleukin-1 enhances epidermal wound healing
28. Cytokine expression in the alkali-burned cornea
29. High bronchoalveolar levels of tumor necrosis factor and its inhibitors, interleukin-1, interferon, and elastase, in patients with adult respiratory distress syndrome after trauma, shock, or sepsis
30. The role of epidermal growth factor (EGF) and its receptor in mucosal protection, adaptation to injury, and ulcer healing: Involvement of EGF-R signal transduction pathways
31. The cytokines NAP-1 (IL-8), MCP-1, IL-1 beta, and GRO in rabbit inflammatory skin lesions produced by the chemical irritant sulfur mustard
32. Distribution of epidermal growth factor receptor and ligands during bronchiolar epithelial repair from naphthalene-induced Clara cell injury in the mouse
33. Determination of endogenous growth factors in human wound fluid: Temporal presence and profiles of secretion