High mobility group box-1 expression correlates with poor outcome in lung injury patients

Pharmacological Research

Volumn 61, Issue 2, 2010, Pages 116-120

  Bitto, Alessandra ^a,b   Barone, Mario ^a   David, Antonio ^a   Polito, Francesca ^a   Familiari, Dario ^a   Monaco, Francesco ^a   Giardina, Massimiliano ^a   David, Teresa ^a   Messina, Roberto ^a   Noto, Alberto ^a   Di Stefano, Vincenzo ^a   Altavilla, Domenica ^a   Bonaiuto, Antonio ^a   Minutoli, Letteria ^a   Guarini, Salvatore ^b   Ottani, Alessandra ^b   Squadrito, Francesco ^a   Venuti, Francesco Saverio ^a  

^a UNIVERSITY OF MESSINA   (Italy)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

BALF; HMGB 1; Lung injury; Real Time PCR

Indexed keywords

ANTIBIOTIC AGENT; BIOLOGICAL MARKER; GLUCOCORTICOID; HIGH MOBILITY GROUP B1 PROTEIN; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1;

ADULT; ARTICLE; BACTERIAL INFECTION; CELL LEVEL; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE ASSOCIATION; GENE EXPRESSION REGULATION; GLASGOW COMA SCALE; HUMAN; HUMAN CELL; INJURY SEVERITY; INTENSIVE CARE UNIT; ITALY; LUNG ALVEOLUS MACROPHAGE; LUNG CONTUSION; LUNG INJURY; LUNG LAVAGE; OUTCOMES RESEARCH; PATIENT REFERRAL; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SURVIVAL; THORAX INJURY; THORAX RADIOGRAPHY;

ADOLESCENT; ADULT; BLOTTING, WESTERN; BRONCHOALVEOLAR LAVAGE FLUID; CASE-CONTROL STUDIES; GLASGOW COMA SCALE; HMGB1 PROTEIN; HUMANS; INJURY SEVERITY SCORE; LINEAR MODELS; LUNG INJURY; MIDDLE AGED; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION; YOUNG ADULT;

EID: 73949153396     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2009.07.014     Document Type: Article

References (21)

1. Miller D.L., and Mansour K.A. Blunt traumatic lung injuries. Thorac Surg Clin 17 (2007) 57-61
2. Wang H., Bloom O., Zhang M., Vishnubhakat J.M., Ombrellino M., Che J., et al. HMG-1 as a late mediator of endotoxin lethality in mice. Science 285 (1999) 248-251
3. Heyde C.E., Tschoeke S.K., Hellmuth M., Hostmann A., Ertel W., and Oberholzer A. Trauma induces apoptosis in human thoracolumbar intervertebral discs. BMC Clin Pathol 6 (2006) 5
4. Andersson U., Erlandsson-Harris H., Yang H., and Tracey K.J. HMGB1 as a DNA-binding cytokine. J Leukoc Biol 72 (2002) 1084-1091
5. Tang D., Shi Y., Kang R., Li T., Xiao W., Wang H., et al. Hydrogen peroxide stimulates macrophages and monocytes to actively release HMGB1. J Leukoc Biol 81 (2007) 741-747
6. Yang R., Harada T., Mollen K.P., Prince J.M., Levy R.M., Englert J.A., et al. Anti-HMGB1 neutralizing antibody ameliorates gut barrier dysfunction and improves survival after hemorrhagic shock. Mol Med 12 (2006) 105-114
7. Champion H.R., Sacco W.J., Carnazzo A.J., Copes W., and Fouty W.J. Trauma score. Crit Care Med 9 (1981) 672-676
8. Champion H.R., Sacco W.J., Copes W.S., Gann D.S., Gennarelli T.A., and Flanagan M.E. A revision of the Trauma Score. J Trauma 29 (1989) 623-629
9. Bitto A., Minutoli L., Altavilla D., Polito F., Fiumara T., Marini H., et al. Simvastatin enhances VEGF production and ameliorates impaired wound healing in experimental diabetes. Pharmacol Res 57 (2008) 159-169
10. van Zoelen M.A., Ishizaka A., Wolthuls E.K., Choi G., van der Poll T., and Schultz M.J. Pulmonary levels of high-mobility group box 1 during mechanical ventilation and ventilator-associated pneumonia. Shock 29 (2008) 441-445
11. Abraham E., Arcaroli J., Carmody A., Wang H., and Tracey K.J. HMG-1 as a mediator of acute lung inflammation. J Immunol 165 (2000) 2950-2954
12. van Zoelen M.A., Yang H., Florquin S., Meijers J.C., Akira S., Arnold B., et al. Role of toll-like receptors 2 and 4, and the receptor for advanced glycation end products in high-mobility group box 1-induced inflammation in vivo. Shock 31 (2009) 280-284
13. Agnello D., Wang H., Yang H., Tracey K.J., and Ghezzi P. HMGB-1, a DNA-binding protein with cytokine activity, induces brain TNF and IL-6 production, and mediates anorexia and taste aversion. Cytokine 18 (2002) 231-236
14. Goldstein R.S., Gallowitsch-Puerta M., Yang L., Rosas-Ballina M., Huston J.M., Czura C.J., et al. Elevated high-mobility group box 1 levels in patients with cerebral and myocardial ischemia. Shock 25 (2006) 571-574
15. Hamada T., Torikai M., Kuwazuru A., Tanaka M., Horai N., Fukuda T., et al. Extracellular high mobility group box chromosomal protein 1 is a coupling factor for hypoxia and inflammation in arthritis. Arthritis Rheum 58 (2008) 2675-2685
16. Bruchfeld A., Qureshi A.R., Lindholm B., Barany P., Yang L., Stenvinkel P., et al. High mobility group box protein-1 correlates with renal function in chronic kidney disease (CKD). Mol Med 14 (2008) 109-115
17. Mantell L.L., Parrish W.R., and Ulloa L. Hmgb-1 as a therapeutic target for infectious and inflammatory disorders. Shock 25 (2006) 4-11
18. Sakamoto Y., Mashiko K., Matsumoto H., Hara Y., Kutsukata N., Takei K., et al. Effect of direct hemoperfusion with a polymyxin B immobilized fiber column on high mobility group box-1 (HMGB-1) in severe septic shock: report of a case. ASAIO J 52 (2006) 37-39
19. Su X., Looney M.R., Gupta N., and Matthay M.A. Receptor for advanced glycation end-products (RAGE) is an indicator of direct lung injury in models of experimental lung injury. Am J Physiol Lung Cell Mol Physiol 297 (2009) L1-L5
20. Calfee C.S., Ware L.B., Eisner M.D., Parsons P.E., Thompson B.T., Wickersham N., et al. Plasma receptor for advanced glycation end products and clinical outcomes in acute lung injury. Thorax 63 (2008) 1083-1089
21. He M., Kubo H., Ishizawa K., Hegab A.E., Yamamoto Y., Yamamoto H., et al. The role of the receptor for advanced glycation end-products in lung fibrosis. Am J Physiol Lung Cell Mol Physiol 293 (2007) L1427-L1436