Intrathecal morphine in anesthesia for cesarean delivery: dose-response relationship for combinations of low-dose intrathecal morphine and spinal bupivacaine

Journal of Clinical Anesthesia

Volumn 20, Issue 3, 2008, Pages 180-185

  Girgin, Nermin K ^a   Gurbet, Alp ^a   Turker, Gurkan ^a   Aksu, Hale ^a   Gulhan, Nevra ^a  

^a ULUDAG UNIVERSITY   (Turkey)

Author keywords

Analgesia; Bupivacaine; Cesarean delivery; Intrathecal; Low dose; Morphine

Indexed keywords

BUPIVACAINE; MORPHINE;

ADULT; ARTICLE; CESAREAN SECTION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; LOW DRUG DOSE; MAJOR CLINICAL STUDY; NAUSEA; PAIN; PATIENT CONTROLLED ANALGESIA; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL; VISUAL ANALOG SCALE; VOMITING;

ADULT; ANALGESIA, PATIENT-CONTROLLED; ANALGESICS, OPIOID; ANESTHESIA, OBSTETRICAL; ANESTHESIA, SPINAL; ANESTHETICS, LOCAL; BUPIVACAINE; CESAREAN SECTION; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; INJECTIONS, SPINAL; MORPHINE; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; POSTOPERATIVE NAUSEA AND VOMITING; PREGNANCY; PRURITUS;

EID: 43849103004     PISSN: 09528180     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jclinane.2007.07.010     Document Type: Article

References (20)

1. Abouleish E., Rawal N., Fallon K., and Hernandez D. Combined intrathecal morphine and bupivacaine for cesarean section. Anesth Analg 67 (1988) 370-374
2. Abboud T.K., Dror A., Mosaad P., et al. Mini-dose intrathecal morphine for the relief of post-cesarean section pain: safety, efficacy, and ventilatory responses to carbon dioxide. Anesth Analg 67 (1988) 137-143
3. Dahl J.B., Jeppesen I.S., Jørgensen H., Wetterslev J., and Møiniche S. Intraoperative and postoperative analgesic efficacy and adverse effects of intrathecal opioids in patients undergoing cesarean section with spinal anesthesia: a qualitative and quantitative systematic review of randomized controlled trials. Anesthesiology 91 (1999) 1919-1927
4. Karaman S., Kocabas S., Uyar M., Hayzaran S., and Firat V. The effects of sufentanil or morphine added to hyperbaric bupivacaine in spinal anaesthesia for caesarean section. Eur J Anaesthesiol 23 (2006) 285-291
5. Choi D.M., Kliffer A.P., and Douglas M.J. Dextromethorphan and intrathecal morphine for analgesia after caesarean section under spinal anaesthesia. Br J Anaesth 90 (2003) 653-658
6. Swart M., Sewell J., and Thomas D. Intrathecal morphine for caesarean section: an assessment of pain relief, satisfaction and side-effects. Anaesthesia 52 (1997) 373-377
7. Milner A.R., Bogod D.G., and Harwood R.J. Intrathecal administration of morphine for elective caesarean section. A comparison between 0.1 mg and 0.2 mg. Anaesthesia 51 (1996) 871-873
8. Terajima K., Onodera H., Kobayashi M., et al. Efficacy of intrathecal morphine for analgesia following elective cesarean section: comparison with previous delivery. J Nippon Med Sch 70 (2003) 327-333
9. Palmer C.M., Emerson S., Volgoropolous D., and Alves D. Dose-response relationship of intrathecal morphine for postcesarean analgesia. Anesthesiology 90 (1999) 437-444
10. Wu Y.W., Seah Y.S., Chung K.T., and Liu M.D. Postoperative pain relief in primigravida caesarean section patients-combination of intrathecal morphine and epinephrine. Acta Anaesthesiol Sin 37 (1999) 111-114
11. Cardoso M.M., Carvalho J.C., Amaro A.R., Prado A.A., and Cappelli E.L. Small doses of intrathecal morphine combined with systemic diclofenac for postoperative pain control after cesarean delivery. Anesth Analg 86 (1998) 538-541
12. Uchiyama A., Nakano S., Ueyama H., Nishimura M., and Tashiro C. Low dose intrathecal morphine and pain relief following caesarean section. Int J Obstet Anesth 3 (1994) 87-91
13. Dahlgren G., Hultstrand C., Jakobsson J., Norman M., Eriksson E.W., and Martin H. Intrathecal sufentanil, fentanyl, or placebo added to bupivacaine for cesarean section. Anesth Analg 85 (1997) 1288-1293
14. Nortcliffe S.A., Shah J., and Buggy D.J. Prevention of postoperative nausea and vomiting after spinal morphine for caesarean section: comparison of cyclizine, dexamethasone and placebo. Br J Anaesth 90 (2003) 665-670
15. Dualé C., Frey C., Bolandard F., Barrière A., and Schoeffler P. Epidural versus intrathecal morphine for postoperative analgesia after caesarean section. Br J Anaesth 91 (2003) 690-694
16. Bailey P.L., Rhondeau S., Schafer P.G., et al. Dose-response pharmacology of intrathecal morphine in human volunteers. Anesthesiology 79 (1993) 49-59
17. Charuluxananan S., Kyokong O., Somboonviboon W., Lertmaharit S., Ngamprasertwong P., and Nimcharoendee K. Nalbuphine versus propofol for treatment of intrathecal morphine-induced pruritus after cesarean delivery. Anesth Analg 93 (2001) 162-165
18. Sarvela J., Halonen P., Soikkeli A., and Korttila K. A double-blinded, randomized comparison of intrathecal and epidural morphine for elective cesarean delivery. Anesth Analg 95 (2002) 436-440
19. Cousins M.J., and Mather L.E. Intrathecal and epidural administration of opioids. Anesthesiology 61 (1984) 276-310
20. Yaksh T.L. Spinal opiate analgesia: characteristics and principles of action. Pain 11 (1981) 293-346