메뉴 건너뛰기




Volumn 19, Issue 1, 2013, Pages 65-71

Effect of recombinant αspi_sub1spii_sub -antitrypsin Fc-fused (aat-fc) protein on the inhibition of inflammatory cytokine production and streptozotocin-induced diabetes

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; CYTOKINE; ELASTASE; HYBRID PROTEIN; IMMUNOGLOBULIN G1; INTERLEUKIN 6; PROTEIN A; PROTEIN FC; STREPTOZOCIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84877764142     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.2119/molmed.2012.00308     Document Type: Article
Times cited : (29)

References (38)
  • 2
    • 10744224092 scopus 로고    scopus 로고
    • Recombinant adeno-associated virus-mediated alpha-1 antitrypsin gene therapy prevents type I diabetes in NOD mice
    • Song S, et al. (2004) Recombinant adeno-associated virus-mediated alpha-1 antitrypsin gene therapy prevents type I diabetes in NOD mice. Gene Ther. 11:181-6.
    • (2004) Gene Ther , vol.11 , pp. 181-186
    • Song, S.1
  • 3
    • 33745662827 scopus 로고    scopus 로고
    • Alpha1-antitrypsin gene therapy modulates cellular immunity and efficiently prevents type 1 diabetes in nonobese diabetic mice
    • Lu Y, et al. (2006) Alpha1-antitrypsin gene therapy modulates cellular immunity and efficiently prevents type 1 diabetes in nonobese diabetic mice. Hum. Gene Ther. 17:625-34.
    • (2006) Hum. Gene Ther , vol.17 , pp. 625-634
    • Lu, Y.1
  • 4
    • 84858776868 scopus 로고    scopus 로고
    • Alpha-1-antitrypsin gene delivery reduces inflammation, increases T-regulatory cell population size and prevents islet allograft rejection
    • Shahaf G, et al. (2011) Alpha-1-antitrypsin gene delivery reduces inflammation, increases T-regulatory cell population size and prevents islet allograft rejection. Mol. Med. 17:1000-11.
    • (2011) Mol. Med , vol.17 , pp. 1000-1011
    • Shahaf, G.1
  • 5
    • 34248178516 scopus 로고    scopus 로고
    • Alpha1-antitrypsin protects beta-cells from apoptosis
    • Zhang B, et al. (2007) Alpha1-antitrypsin protects beta-cells from apoptosis. Diabetes. 56:1316-23.
    • (2007) Diabetes , vol.56 , pp. 1316-1323
    • Zhang, B.1
  • 6
    • 55849101706 scopus 로고    scopus 로고
    • Alpha1-antitrypsin monotherapy induces immune tolerance during islet allograft transplantation in mice
    • Lewis EC, et al. (2008) Alpha1-antitrypsin monotherapy induces immune tolerance during islet allograft transplantation in mice. Proc. Natl. Acad. Sci. U. S. A. 105:16236-41.
    • (2008) Proc. Natl. Acad. Sci. U. S. A , vol.105 , pp. 16236-16241
    • Lewis, E.C.1
  • 7
    • 55849136929 scopus 로고    scopus 로고
    • Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice
    • Koulmanda M, et al. (2008) Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice. Proc. Natl. Acad. Sci. U. S. A. 105:16242-7.
    • (2008) Proc. Natl. Acad. Sci. U. S. A , vol.105 , pp. 16242-16247
    • Koulmanda, M.1
  • 8
    • 41049098117 scopus 로고    scopus 로고
    • Alpha-1 antitrypsin treatment of spontaneously diabetic nonobese diabetic mice receiving islet allografts
    • Pileggi A, et al. (2008) Alpha-1 antitrypsin treatment of spontaneously diabetic nonobese diabetic mice receiving islet allografts. Transplant. Proc. 40:457-8.
    • (2008) Transplant. Proc , vol.40 , pp. 457-458
    • Pileggi, A.1
  • 9
    • 0029385305 scopus 로고
    • Alpha-1-antitrypsin, albumin and whole protein in meconium and stools during the first days of life in the neonate
    • in Polish
    • Lisowska-Myjak B, Pachecka J, Antoniewicz B, Krawczyk A, Jozwik A. (1995) Alpha-1-antitrypsin, albumin and whole protein in meconium and stools during the first days of life in the neonate [in Polish]. Pediatr. Pol. 70:819-26.
    • (1995) Pediatr. Pol , vol.70 , pp. 819-826
    • Lisowska-Myjak, B.1    Pachecka, J.2    Antoniewicz, B.3    Krawczyk, A.4    Jozwik, A.5
  • 10
    • 22044440445 scopus 로고    scopus 로고
    • Two-dimensional fluorescence difference gel electrophoresis analysis of the urine proteome in human diabetic nephropathy
    • Sharma K, et al. (2005) Two-dimensional fluorescence difference gel electrophoresis analysis of the urine proteome in human diabetic nephropathy. Proteomics. 5:2648-55.
    • (2005) Proteomics , vol.5 , pp. 2648-2655
    • Sharma, K.1
  • 11
    • 0037427618 scopus 로고    scopus 로고
    • Antigenic and functional levels of alpha-1-antitrypsin in serum during normal and diabetic pregnancy
    • Lisowska-Myjak B, Pachecka J. (2003) Antigenic and functional levels of alpha-1-antitrypsin in serum during normal and diabetic pregnancy. Eur. J. Obstet. Gynecol. Reprod. Biol. 106:31-5.
    • (2003) Eur. J. Obstet. Gynecol. Reprod. Biol , vol.106 , pp. 31-35
    • Lisowska-Myjak, B.1    Pachecka, J.2
  • 12
    • 33846036369 scopus 로고    scopus 로고
    • Serum protease inhibitor concentrations and total antitrypsin activity in diabetic and non-diabetic children during adolescence
    • Lisowska-Myjak B, Pachecka J, Kaczynska B, Miszkurka G, Kadziela K. (2006) Serum protease inhibitor concentrations and total antitrypsin activity in diabetic and non-diabetic children during adolescence. Acta Diabetol. 43:88-92.
    • (2006) Acta Diabetol , vol.43 , pp. 88-92
    • Lisowska-Myjak, B.1    Pachecka, J.2    Kaczynska, B.3    Miszkurka, G.4    Kadziela, K.5
  • 14
    • 67349122300 scopus 로고    scopus 로고
    • Serum trypsin inhibitory capacity in normal pregnancy and gestational diabetes mellitus
    • Yaghmaei M, et al. (2009) Serum trypsin inhibitory capacity in normal pregnancy and gestational diabetes mellitus. Diabetes Res. Clin. Pract. 84:201-4.
    • (2009) Diabetes Res. Clin. Pract , vol.84 , pp. 201-204
    • Yaghmaei, M.1
  • 15
    • 0001402344 scopus 로고
    • Hereditary deficiency of serum alpha-Lantitrypsin
    • Kueppers F, Briscoe WA, Bearn AG. (1964) Hereditary deficiency of serum alpha-Lantitrypsin. Science. 146:1678-9.
    • (1964) Science , vol.146 , pp. 1678-1679
    • Kueppers, F.1    Briscoe, W.A.2    Bearn, A.G.3
  • 16
    • 0000461577 scopus 로고
    • Pulmonary emphysema and alpha1-antitrypsin deficiency
    • Eriksson S. (1964) Pulmonary emphysema and alpha1-antitrypsin deficiency. Acta. Med. Scand. 175:197-205.
    • (1964) Acta. Med. Scand , vol.175 , pp. 197-205
    • Eriksson, S.1
  • 17
    • 79953858686 scopus 로고    scopus 로고
    • Efficacy of alpha1-antitrypsin augmentation therapy in conditions other than pulmonary emphysema
    • Blanco I, Lara B, de Serres F,(2011) Efficacy of alpha1-antitrypsin augmentation therapy in conditions other than pulmonary emphysema. Orphanet. J. Rare Dis. 6:14.
    • (2011) Orphanet. J. Rare Dis , vol.6 , pp. 14
    • Blanco, I.1    Lara, B.2    de Serres, F.3
  • 18
    • 0022257475 scopus 로고
    • DNA restriction fragments associated with alpha 1-antitrypsin indicate a single origin for deficiency allele PI Z
    • Cox DW, Woo SL, Mansfield T. (1985) DNA restriction fragments associated with alpha 1-antitrypsin indicate a single origin for deficiency allele PI Z. Nature. 316:79-81.
    • (1985) Nature , vol.316 , pp. 79-81
    • Cox, D.W.1    Woo, S.L.2    Mansfield, T.3
  • 19
    • 77952770299 scopus 로고    scopus 로고
    • Evidence for unfolded protein response activation in monocytes from individuals with alpha-1 antitrypsin deficiency
    • Carroll TP, et al. (2010) Evidence for unfolded protein response activation in monocytes from individuals with alpha-1 antitrypsin deficiency. J. Immunol. 184:4538-46.
    • (2010) J. Immunol , vol.184 , pp. 4538-4546
    • Carroll, T.P.1
  • 20
    • 84991202826 scopus 로고    scopus 로고
    • Prolastin, a pharmaceutical preparation of purified human alpha1-antitrypsin, blocks endotoxin-mediated cytokine release
    • Nita I, Hollander C, Westin U, Janciauskiene SM. (2005) Prolastin, a pharmaceutical preparation of purified human alpha1-antitrypsin, blocks endotoxin-mediated cytokine release. Respir. Res. 6:12.
    • (2005) Respir. Res , vol.6 , pp. 12
    • Nita, I.1    Hollander, C.2    Westin, U.3    Janciauskiene, S.M.4
  • 21
    • 84858699084 scopus 로고    scopus 로고
    • Acute-phase protein alpha1-antitrypsin inhibits neutrophil calpain I and induces random migration
    • Al-Omari M, et al. (2011) Acute-phase protein alpha1-antitrypsin inhibits neutrophil calpain I and induces random migration. Mol. Med. 17:865-74.
    • (2011) Mol. Med , vol.17 , pp. 865-874
    • Al-Omari, M.1
  • 22
    • 36248935622 scopus 로고    scopus 로고
    • TNF-alpha-induced self expression in human lung endothelial cells is inhibited by native and oxidized alpha1-antitrypsin
    • Subramaniyam D, et al. (2008) TNF-alpha-induced self expression in human lung endothelial cells is inhibited by native and oxidized alpha1-antitrypsin. Int. J. Biochem. Cell Biol. 40:258-71.
    • (2008) Int. J. Biochem. Cell Biol , vol.40 , pp. 258-271
    • Subramaniyam, D.1
  • 23
    • 57349149443 scopus 로고    scopus 로고
    • Alpha1-antitrypsin inhibits the activity of the matriptase catalytic domain in vitro
    • Janciauskiene S, et al. (2008) Alpha1-antitrypsin inhibits the activity of the matriptase catalytic domain in vitro. Am. J. Respir. Cell Mol. Biol. 39:631-7.
    • (2008) Am. J. Respir. Cell Mol. Biol , vol.39 , pp. 631-637
    • Janciauskiene, S.1
  • 25
    • 0030873292 scopus 로고    scopus 로고
    • Atopy, asthma, and emphysema in patients with severe alpha-1-antitrypysin deficiency
    • Eden E, et al. (1997) Atopy, asthma, and emphysema in patients with severe alpha-1-antitrypysin deficiency. Am. J. Respir. Crit. Care Med. 156:68-74.
    • (1997) Am. J. Respir. Crit. Care Med , vol.156 , pp. 68-74
    • Eden, E.1
  • 26
    • 0029925466 scopus 로고    scopus 로고
    • C-antineutrophil cytoplasmic antibody positivity in vasculitis patients is associated with the Z allele of alpha-1-antitrypsin, and P-antineutrophil cytoplasmic antibody positivity with the S allele
    • Griffith ME, Lovegrove JU, Gaskin G, Whitehouse DB, Pusey CD. (1996) C-antineutrophil cytoplasmic antibody positivity in vasculitis patients is associated with the Z allele of alpha-1-antitrypsin, and P-antineutrophil cytoplasmic antibody positivity with the S allele. Nephrol. Dial. Transplant. 11:438-43.
    • (1996) Nephrol. Dial. Transplant , vol.11 , pp. 438-443
    • Griffith, M.E.1    Lovegrove, J.U.2    Gaskin, G.3    Whitehouse, D.B.4    Pusey, C.D.5
  • 27
    • 0029963017 scopus 로고    scopus 로고
    • Alpha 1-antitrypsin deficiency: Evaluation of bronchiectasis with CT
    • King MA, et al. (1996) Alpha 1-antitrypsin deficiency: evaluation of bronchiectasis with CT. Radiology. 199:137-41.
    • (1996) Radiology , vol.199 , pp. 137-141
    • King, M.A.1
  • 28
    • 77958066901 scopus 로고    scopus 로고
    • Intradermal alpha1-antitrypsin therapy avoids fatal anaphylaxis, prevents type 1 diabetes and reverses hyperglycaemia in the NOD mouse model of the disease
    • Ma H, et al. (2010) Intradermal alpha1-antitrypsin therapy avoids fatal anaphylaxis, prevents type 1 diabetes and reverses hyperglycaemia in the NOD mouse model of the disease. Diabetologia. 53:2198-204.
    • (2010) Diabetologia , vol.53 , pp. 2198-2204
    • Ma, H.1
  • 29
    • 79959516887 scopus 로고    scopus 로고
    • Alpha-1 antitrypsin inhibits caspase-1 and protects from acute myocardial ischemia-reperfusion injury
    • Toldo S, et al. (2011) Alpha-1 antitrypsin inhibits caspase-1 and protects from acute myocardial ischemia-reperfusion injury. J. Mol. Cell. Cardiol. 51:244-51.
    • (2011) J. Mol. Cell. Cardiol , vol.51 , pp. 244-251
    • Toldo, S.1
  • 30
    • 80855128776 scopus 로고    scopus 로고
    • Inhibition of IL-32 activation by alpha-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model
    • Marcondes AM, et al. (2011) Inhibition of IL-32 activation by alpha-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model. Blood. 118:5031-9.
    • (2011) Blood , vol.118 , pp. 5031-5039
    • Marcondes, A.M.1
  • 31
    • 84862908801 scopus 로고    scopus 로고
    • Alpha-1-antitrypsin monotherapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantation
    • Tawara I, et al. (2012) Alpha-1-antitrypsin monotherapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantation. Proc. Natl. Acad. Sci. U. S. A. 109:564-9.
    • (2012) Proc. Natl. Acad. Sci. U. S. A , vol.109 , pp. 564-569
    • Tawara, I.1
  • 32
    • 79953250407 scopus 로고    scopus 로고
    • Alpha 1-antitrypsin enhances insulin secretion and prevents cytokine-mediated apoptosis in pancreatic beta-cells
    • Kalis M, Kumar R, Janciauskiene S, Salehi A, Cilio CM. (2010) Alpha 1-antitrypsin enhances insulin secretion and prevents cytokine-mediated apoptosis in pancreatic beta-cells. Islets. 2:185-9.
    • (2010) Islets , vol.2 , pp. 185-189
    • Kalis, M.1    Kumar, R.2    Janciauskiene, S.3    Salehi, A.4    Cilio, C.M.5
  • 33
    • 34548156165 scopus 로고    scopus 로고
    • Ex vivo gene transfer of viral interleukin-10 to BB rat islets: No protection after transplantation to diabetic BB rats
    • Kuttler B, et al. (2007) Ex vivo gene transfer of viral interleukin-10 to BB rat islets: no protection after transplantation to diabetic BB rats. J. Cell Mol. Med. 11:868-80.
    • (2007) J. Cell Mol. Med , vol.11 , pp. 868-880
    • Kuttler, B.1
  • 34
    • 0029908555 scopus 로고    scopus 로고
    • Levels of von Willebrand factor, insulin resistance syndrome, and a common vWF gene polymorphism in non-insulin-dependent (type 2) diabetes mellitus
    • Heywood DM, Mansfield MW, Grant PJ. (1996) Levels of von Willebrand factor, insulin resistance syndrome, and a common vWF gene polymorphism in non-insulin-dependent (type 2) diabetes mellitus. Diabet. Med. 13:720-5.
    • (1996) Diabet. Med , vol.13 , pp. 720-725
    • Heywood, D.M.1    Mansfield, M.W.2    Grant, P.J.3
  • 35
    • 0028898329 scopus 로고
    • Polymorphisms of the human hexokinase II gene: Lack of association with NIDDM and insulin resistance
    • Laakso M, Malkki M, Kekalainen P, Kuusisto J, Deeb SS. (1995) Polymorphisms of the human hexokinase II gene: lack of association with NIDDM and insulin resistance. Diabetologia. 38:617-22.
    • (1995) Diabetologia , vol.38 , pp. 617-622
    • Laakso, M.1    Malkki, M.2    Kekalainen, P.3    Kuusisto, J.4    Deeb, S.S.5
  • 37
    • 55149115148 scopus 로고    scopus 로고
    • An association between type 2 diabetes and alpha-antitrypsin deficiency
    • Sandstrom CS, et al. (2008) An association between type 2 diabetes and alpha-antitrypsin deficiency. Diabet. Med. 25:1370-3.
    • (2008) Diabet. Med , vol.25 , pp. 1370-1373
    • Sandstrom, C.S.1
  • 38
    • 0037387603 scopus 로고    scopus 로고
    • Progression of atherosclerosis is associated with variation in the alpha1-antitrypsin gene
    • Talmud PJ, et al. (2003) Progression of atherosclerosis is associated with variation in the alpha1-antitrypsin gene. Arterioscler. Thromb. Vasc. Biol. 23:644-9.
    • (2003) Arterioscler. Thromb. Vasc. Biol , vol.23 , pp. 644-649
    • Talmud, P.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.