Levels of von Willebrand factor, insulin resistance syndrome, and a common vWF gene polymorphism in noninsulin-dependent (Type 2) diabetes mellitus

Diabetic Medicine

Volumn 13, Issue 8, 1996, Pages 720-725

  Heywood, D M ^a,b   Mansfield, M W ^a   Grant, P J ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b LEEDS GENERAL INFIRMARY   (United Kingdom)

Author keywords

Aat II; Genotype; Insulin resistance syndrome; Non insulin dependent diabetes; von Willebrand factor

Indexed keywords

VON WILLEBRAND FACTOR;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; FEMALE; GENOTYPE; HUMAN; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

AGED; BASE SEQUENCE; DIABETES MELLITUS, TYPE 2; DNA PRIMERS; FEMALE; GENOTYPE; HUMANS; INSULIN RESISTANCE; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; SYNDROME; VON WILLEBRAND FACTOR;

EID: 0029908555     PISSN: 07423071     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9136(199608)13:8<720::AID-DIA176>3.0.CO;2-0     Document Type: Article

References (30)

1. Kannel WB. Lipids, diabetes, and coronary heart disease: insights from the Framingham study. Am Heart J 1985; 110: 1100-1106.
2. Ganda OP. Pathogenesis of macrovascular disease in the human diabetic. Diabetes 1980; 29: 931-940.
3. Pyorala K. Relationship of glucose tolerance and plasma insulin to the incidence of coronary heart disease. Results from two population studies in Finland. Diabetes Care 1979; 2: 131-141.
4. Reaven GM. Role of IR in human disease. Diabetes 1988; 37: 1595-1607.
5. Landin K, Stigendal L, Eriksson E, Krotkiewski M, Risberg B, Tengborn L, Smith U. Abdominal obesity is associated with an impaired fibrinolytic activity and elevated plasminogen activator inhibitor-1. Metabolism 1990; 39: 1044-1048.
6. Landin K, Tengborn L, Smith U. Elevated fibrinogen and plasminogen activator inhibitors (PAI-1) in hypertension are related to metabolic risk factors for cardiovascular disease. J Intern Med 1990; 227: 273-278.
7. Nilsson TK, Boman K, Bjerle P, Hallmans G, Hellsten G. von Willebrand factor and fibrinolytic variables are differently affected in the IR syndrome. J Intern Med 1994; 235: 419-423.
8. Harkness J. The viscosity of human blood plasma: its measurement in health and disease. Biorheology 1971; 8: 171-193.
9. Stehouwer CDA. Is the increase in plasma von Willebrand factor concentrations in diabetes mellitus related to insulin levels? (Letter). Thromb Haemost 1994; 71: 398.
10. Morise T, Koni I, Takeuchi Y, Takeda R, Kawano M. Increased plasma levels of immunoreactive endothelin and von Willebrand Factor in NIDDM patients. Diabetes Care 1995; 18: 87-89.
11. Jansson J, Nilsson TK, Johnson O. von Willebrand factor in plasma: a novel risk factor for recurrent myocardial infarction and death. Br Heart J 1991; 66: 351-355.
12. Margullis T, David M, Maor N, Soff GA, Grenadier E, Palant A, Aghai E. The von Willebrand factor in myocardial infarction and unstable angina: A kinetic study. Thromb Haemost 1986; 55: 366-368.
13. Thompson SG, Kienast J, Pyke SDM, Haverkate F, van de Loo JCW. Hemostatic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris. N Engl J Med 1995; 332: 635-641.
14. Bowen DJ, Webb CE, Peake IR, Bloom AL. Aat II polymorphism in von Willebrand factor gene at codon 471. Nucl Acids Res 1991; 19: 3159.
15. Conlan MG, Folson AR, Finch A, Davis CE, Solie P, Marcucci G, Wu KK. Associations of factor VIII and von Willebrand factor with age, race, sex, and risk factors for atherosclerosis. The Atherosclerosis Risk in Communities (ARIC) study. Thromb Haemost 1993; 70: 380-385.
16. Stehouwer CDA, Nauta JJP, Zelderhurst GC, Hackeng WHL, Mulder PGH, den Oltolander GJH. Urinary albumin excretion, cardiovascular disease, and endothelial dysfunction in non-insulin-dependent diabetes mellitus. Lancet 1992; 70: 319-323.
17. Blann AD, Naqvi T, Waite MA, McCollum CN. von Willebrand factor and endothelial damage in essential hypertension. J Hum Hypertens 1993; 7: 107.
18. Blann AD. Increased levels of von Willebrand factor antigen in smokers may be due to lipid peroxidases. Med Sci Res 1991; 19: 535-536.
19. Duffy A, Blann AD, Anderson J, Miller JP, Gowland E, McCollum CN. Increased von Willebrand factor antigen in familial hypercholesterolaemia with or without vascular disease (Abstract). Atherosclerosis 1991; 90: 226.
20. Mansfield MW, Stickland MH, Grant PJ. Environmental and genetic factors in relation to elevated circulating levels of plasminogen activator inhibitor-1 in Caucasian patients with non-insulin-dependent diabetes mellitus. Thromb Haemost 1995; 74: 842-847.
21. Marbet GA, Duckert F. Fibrinogen. In: Jespersen J, Bertina RM, Haverkate F, eds. ECAT assay procedures. A Manual of Laboratory Techniques. Dordrecht: Kluwer, 1992: 47-55.
22. Mansfield MW, Stickland MH, Carter AM, Grant PJ. Polymorphisms of the plasminogen activator inhibitor-1 gene in type 1 and NIDDM and in patients with diabetic retinopathy. Thromb Haemost 1994; 71: 731-736.
23. Kannal WB, Wolf PA, Castelli WP, D'Agostino RB. Fibrinogen and risk of cardiovascular disease. The Framingham Study. J Am Med Assoc 1987; 258: 1183-1186.
24. Meade TW, Mellows S, Brozovic M, Miller GJ, Chakrabarti RR, Haines AP, et al. Haemostatic function and ischaemic heart disease: principal results of the Northwick Park Heart Study. Lancet 1986; 2: 533-537.
25. ECAT Angina Pectoris Study Group. ECAT angina pectoris study: baseline associations of haemostatic factors with extent of coronary arteriosclerosis and other coronary risk factors in 3000 patients with angina pectoris undergoing coronary angiography. Eur Heart J 1993; 14: 8-17.
26. Heywood DM, Mansfield MW, Grant PJ. Factor VII gene polymorphisms, Factor VII C levels and features of insulin resistance in non-insulin-dependent diabetes mellitus. Thromb Haemost 1996; 75: 401-406.
27. Jeremic M, Weisert O, Gedde-Dahl TW. Factor VIII (AHG) levels in 1016 regular blood donors. The effects of age, sex, and ABO blood groups. Scand J Clin Lab Invest 1976; 36: 461-466.
28. Balleisen L, Bailey J, Epping P-H, Sculte H, van de Loo J. Epidemiological study on factor VII, factor VIII and fibrinogen in an industrial population: I. Baseline data on the relation to age, gender, body-weight, smoking, alcohol, pill-using, and menopause. Thromb Haemost 1985; 54: 475-479.
29. Meade TW, North WRS, Chakrabarti R, Haines AP, Stirling Y. Population-based distributions of haemostatic variables. Br Med Bull 1977; 33: 283-288.
30. Wahlberg TB, Blomback M, Magnusson D. Influence of sex, blood group, secretor character, smoking habits, acetylsalicylic acid, oral contraceptives, fasting and general health state on blood coagulation variables in randomly selected young adults. Haemostasis 1984; 14: 312-319.