Lysophosphatidic acid impairs glucose homeostasis and inhibits insulin secretion in high-fat diet obese mice

Diabetologia

Volumn 56, Issue 6, 2013, Pages 1394-1402

  Rancoule, C ^a   Attane C ^b   Gres S ^a   Fournel, A ^a   Dusaulcy, R ^a   Bertrand, C ^a   Vinel, C ^a   Treguer K ^a   Prentki, M ^b,c   Valet, P ^a   Saulnier Blache, J S ^a  

^a University Hospital of Toulouse   (France)

^b CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Antagonist; Glucose homeostasis; Insulin; Lysophosphatidic acid; Obesity; Receptors

Indexed keywords

AGENTS AFFECTING CARBOHYDRATE METABOLISM; ANTIOBESITY AGENT; GLYCOGEN; INSULIN; KI 16425; LYSOPHOSPHATIDIC ACID; LYSOPHOSPHATIDIC ACID RECEPTOR; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CELL SIZE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DIET RESTRICTION; DRUG MECHANISM; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; GLUCOSE OXIDATION; GLUCOSE TOLERANCE; GLUCOSE TRANSPORT; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; INSULIN RELEASE; LIPID DIET; MALE; MORPHOLOGY; MOUSE; MUSCLE METABOLISM; NONHUMAN; OBESITY; PANCREAS; PANCREAS ISLET CELL; PRIORITY JOURNAL; SKELETAL MUSCLE;

ADIPOCYTES; ANIMALS; BODY WEIGHT; DIET, HIGH-FAT; GENE EXPRESSION REGULATION; GLUCOSE; GLYCOGEN; HOMEOSTASIS; INSULIN; ISOXAZOLES; LIPIDS; LYSOPHOSPHOLIPIDS; MALE; MICE; MICE, INBRED C57BL; MICE, OBESE; MUSCLE, SKELETAL; OXYGEN; PROPIONATES; TIME FACTORS;

EID: 84877739633     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-013-2891-3     Document Type: Article

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