The contribution of N2O3to the cytotoxicity of the nitric oxide donor DETA/NO: An emerging role for S-nitrosylation

Bioscience Reports

Volumn 33, Issue 2, 2013, Pages 333-349

  Ali, Ahlam A ^a   Coulter, Jonathan A ^a   Ogle, Claire H ^a   Migaud, Marie M ^a   Hirst, David G ^a   Robson, Tracy ^a   McCarthy, Helen O ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Cytotoxicity; Hypoxia; Nitric oxide; S nitrosylation

Indexed keywords

2,2' (HYDROXYNITROSOHYDRAZONO) BIS ETHANIMINE; DINITROGEN TRIOXIDE; FAS ANTIGEN; GLUTATHIONE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NITRIC OXIDE DONOR; PEROXYNITRITE; PROTEIN P53; REACTIVE NITROGEN SPECIES; SCAVENGER; UNCLASSIFIED DRUG; 1-HYDROXY-2-OXO-3,3-BIS(2-AMINOETHYL)-1-TRIAZENE; 3,3 BIS(2 AMINOETHYL) 1 HYDROXY 2 OXOTRIAZENE; HIF1A PROTEIN, HUMAN; NITRIC OXIDE; NITROGEN OXIDE; NITROGEN TRIOXIDE; OXYGEN; TRIAZENE DERIVATIVE;

APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL HYPOXIA; CYTOTOXICITY; FLUOROMETRY; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; NITROSYLATION; OXYGEN TENSION; PROTEIN DEPLETION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; BIOSYNTHESIS; CHEMISTRY; DRUG EFFECT; METABOLISM; TUMOR CELL LINE;

APOPTOSIS; CELL HYPOXIA; CELL LINE, TUMOR; GLUTATHIONE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; NITRIC OXIDE; NITRIC OXIDE DONORS; NITROGEN OXIDES; OXYGEN; REACTIVE NITROGEN SPECIES; SIGNAL TRANSDUCTION; TRIAZENES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84877734382     PISSN: 01448463     EISSN: 15734935     Source Type: Journal    
DOI: 10.1042/BSR20120120     Document Type: Article

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