메뉴 건너뛰기




Volumn 26, Issue 3, 2013, Pages 282-288

Update on bacterial meningitis: Epidemiology, trials and genetic association studies

Author keywords

adjuvant therapy; antibiotics; bacterial meningitis; genetics; randomized controlled trials; vaccination

Indexed keywords

CEFOTAXIME; CEFTRIAXONE; DEXAMETHASONE; GENTAMICIN; GLYCEROL; PARACETAMOL; PENICILLIN DERIVATIVE;

EID: 84877715908     PISSN: 13507540     EISSN: 14736551     Source Type: Journal    
DOI: 10.1097/WCO.0b013e328360415c     Document Type: Review
Times cited : (29)

References (72)
  • 3
    • 6944235930 scopus 로고    scopus 로고
    • Clinical features and prognostic factors in adults with bacterial meningitis
    • van de Beek D, de Gans J, Spanjaard L, et al. Clinical features and prognostic factors in adults with bacterial meningitis. N Engl J Med 2004; 351:1849-1859.
    • (2004) N Engl J Med , vol.351 , pp. 1849-1859
    • Van De Beek, D.1    De Gans, J.2    Spanjaard, L.3
  • 4
    • 77954618806 scopus 로고    scopus 로고
    • Epidemiology, diagnosis, and antimicrobial treatment of acute bacterial meningitis
    • Brouwer MC, Tunkel AR, van de Beek D. Epidemiology, diagnosis, and antimicrobial treatment of acute bacterial meningitis. Clin Microbiol Rev 2010; 23:467-492.
    • (2010) Clin Microbiol Rev , vol.23 , pp. 467-492
    • Brouwer, M.C.1    Tunkel, A.R.2    Van De Beek, D.3
  • 6
    • 79957445348 scopus 로고    scopus 로고
    • Bacterial meningitis in the United States 1998-2007
    • Thigpen MC, Whitney CG, Messonnier NE, et al. Bacterial meningitis in the United States, 1998-2007. N Engl J Med 2011; 364:2016-2025.
    • (2011) N Engl J Med , vol.364 , pp. 2016-2025
    • Thigpen, M.C.1    Whitney, C.G.2    Messonnier, N.E.3
  • 8
    • 49849086286 scopus 로고    scopus 로고
    • The diagnosis and management of acute bacterial meningitis in resource-poor settings
    • Scarborough M, Thwaites GE. The diagnosis and management of acute bacterial meningitis in resource-poor settings. Lancet Neurol 2008; 7:637-648.
    • (2008) Lancet Neurol , vol.7 , pp. 637-648
    • Scarborough, M.1    Thwaites, G.E.2
  • 10
    • 79953048814 scopus 로고    scopus 로고
    • Glycerol adjuvant therapy in adults with bacterial meningitis in a high HIV seroprevalence setting in Malawi: A double-blind, randomised controlled trial
    • Ajdukiewicz KM, Cartwright KE, Scarborough M, et al. Glycerol adjuvant therapy in adults with bacterial meningitis in a high HIV seroprevalence setting in Malawi: a double-blind, randomised controlled trial. Lancet Infect Dis 2011; 11:293-300.
    • (2011) Lancet Infect Dis , vol.11 , pp. 293-300
    • Ajdukiewicz, K.M.1    Cartwright, K.E.2    Scarborough, M.3
  • 11
    • 80053419939 scopus 로고    scopus 로고
    • Complement component 5 contributes to poor disease outcome in humans and mice with pneumococcal meningitis
    • Woehrl B, Brouwer MC, Murr C, et al. Complement component 5 contributes to poor disease outcome in humans and mice with pneumococcal meningitis. J Clin Invest 2011; 121:3943-3953.
    • (2011) J Clin Invest , vol.121 , pp. 3943-3953
    • Woehrl, B.1    Brouwer, M.C.2    Murr, C.3
  • 12
    • 84873267646 scopus 로고    scopus 로고
    • Common polymorphisms in the complement system and susceptibility to bacterial meningitis
    • Adriani KS, Brouwer MC, Geldhoff M, et al. Common polymorphisms in the complement system and susceptibility to bacterial meningitis. J Infect 2013; 66:255-262.
    • (2013) J Infect , vol.66 , pp. 255-262
    • Adriani, K.S.1    Brouwer, M.C.2    Geldhoff, M.3
  • 13
    • 84862078531 scopus 로고    scopus 로고
    • Genetic variation in the beta2-adrenocepter gene is associated with susceptibility to bacterial meningitis in adults
    • Adriani KS, Brouwer MC, Baas F, et al. Genetic variation in the beta2-adrenocepter gene is associated with susceptibility to bacterial meningitis in adults. PLoS One 2012; 7:e37618.
    • (2012) PLoS One , vol.7
    • Adriani, K.S.1    Brouwer, M.C.2    Baas, F.3
  • 14
    • 84867329224 scopus 로고    scopus 로고
    • Genetic variation in GLCCI1 and dexamethasone in bacterial meningitis
    • Brouwer MC, van der Ende A, Baas F, van de Beek D. Genetic variation in GLCCI1 and dexamethasone in bacterial meningitis. J Infect 2012; 65:465-467.
    • (2012) J Infect , vol.65 , pp. 465-467
    • Brouwer, M.C.1    Van Der Ende, A.2    Baas, F.3    Van De Beek, D.4
  • 15
    • 84861477874 scopus 로고    scopus 로고
    • Polymorphisms in Toll-like receptors 2, 4, and 9 are highly associated with hearing loss in survivors of bacterial meningitis
    • van Well GT, Sanders MS, Ouburg S, et al. Polymorphisms in Toll-like receptors 2, 4, and 9 are highly associated with hearing loss in survivors of bacterial meningitis. PLoS One 2012; 7:e35837.
    • (2012) PLoS One , vol.7
    • Van Well, G.T.1    Sanders, M.S.2    Ouburg, S.3
  • 18
    • 0034076466 scopus 로고    scopus 로고
    • Worldwide Haemophilus influenzae type b disease at the beginning of the 21st century: Global analysis of the disease burden 25 years after the use of the polysaccharide vaccine and a decade after the advent of conjugates
    • DOI 10.1128/CMR.13.2.302-317.2000
    • Peltola H. Worldwide Haemophilus influenzae type b disease at the beginning of the 21st century: global analysis of the disease burden 25 years after the use of the polysaccharide vaccine and a decade after the advent of conjugates. Clin Microbiol Rev 2000; 13:302-317. (Pubitemid 30205428)
    • (2000) Clinical Microbiology Reviews , vol.13 , Issue.2 , pp. 302-317
    • Peltola, H.1
  • 19
    • 61849099863 scopus 로고    scopus 로고
    • Surveillance for Streptococcus pneumoniae meningitis in children aged 5 years: Implications for immunization in Uganda
    • Kisakye A, Makumbi I, Nansera D, et al. Surveillance for Streptococcus pneumoniae meningitis in children aged
    • (2009) Clin Infect Dis , vol.48 , Issue.SUPPL. 2
    • Kisakye, A.1    Makumbi, I.2    Nansera, D.3
  • 20
    • 61849096604 scopus 로고    scopus 로고
    • Incidence, seasonality, age distribution, and mortality of pneumococcal meningitis in Burkina Faso and Togo
    • Traore Y, Tameklo TA, Njanpop-Lafourcade BM, et al. Incidence, seasonality, age distribution, and mortality of pneumococcal meningitis in Burkina Faso and Togo. Clin Infect Dis 2009; 48 (Suppl 2):S181-S189.
    • (2009) Clin Infect Dis , vol.48 , Issue.SUPPL. 2
    • Traore, Y.1    Tameklo, T.A.2    Njanpop-Lafourcade, B.M.3
  • 21
    • 78149387943 scopus 로고    scopus 로고
    • Systematic evaluation of serotypes causing invasive pneumococcal disease among children under five: The pneumococcal global serotype project
    • Johnson HL, Deloria-Knoll M, Levine OS, et al. Systematic evaluation of serotypes causing invasive pneumococcal disease among children under five: the pneumococcal global serotype project. PLoS Med 2010; 7.
    • (2010) PLoS Med , pp. 7
    • Johnson, H.L.1    Deloria-Knoll, M.2    Levine, O.S.3
  • 22
    • 84861975144 scopus 로고    scopus 로고
    • Critical episodes in the understanding and control of epidemic meningococcal meningitis
    • Artenstein AW, Laforce FM. Critical episodes in the understanding and control of epidemic meningococcal meningitis. Vaccine 2012; 30:4701-4707.
    • (2012) Vaccine , vol.30 , pp. 4701-4707
    • Artenstein, A.W.1    Laforce, F.M.2
  • 23
    • 0036898985 scopus 로고    scopus 로고
    • Chronicle of an outbreak foretold: Meningococcal meningitis W135 in Burkina Faso
    • DOI 10.1016/S1473-3099(02)00455-3
    • Decosas J, Koama JB. Chronicle of an outbreak foretold: meningococcal meningitis W135 in Burkina Faso. Lancet Infect Dis 2002; 2:763-765. (Pubitemid 35434562)
    • (2002) Lancet Infectious Diseases , vol.2 , Issue.12 , pp. 763-765
    • Decosas, J.1    Koama, J.-B.T.2
  • 24
    • 84861117523 scopus 로고    scopus 로고
    • The changing and dynamic epidemiology of meningococcal disease
    • Halperin SA, Bettinger JA, Greenwood B, et al. The changing and dynamic epidemiology of meningococcal disease. Vaccine 2012; 30S:B26-B36.
    • (2012) Vaccine , vol.30
    • Halperin, S.A.1    Bettinger, J.A.2    Greenwood, B.3
  • 25
    • 77951429827 scopus 로고    scopus 로고
    • Advances in the development of vaccines against Neisseria meningitidis
    • Tan LK, Carlone GM, Borrow R. Advances in the development of vaccines against Neisseria meningitidis. N Engl J Med 2010; 362:1511-1520.
    • (2010) N Engl J Med , vol.362 , pp. 1511-1520
    • Tan, L.K.1    Carlone, G.M.2    Borrow, R.3
  • 27
    • 84866614844 scopus 로고    scopus 로고
    • Serogroup A meningococcal conjugate vaccination in Burkina Faso: Analysis of national surveillance data
    • Novak RT, Kambou JL, Diomande FV, et al. Serogroup A meningococcal conjugate vaccination in Burkina Faso: analysis of national surveillance data. Lancet Infect Dis 2012; 12:757-764.
    • (2012) Lancet Infect Dis , vol.12 , pp. 757-764
    • Novak, R.T.1    Kambou, J.L.2    Diomande, F.V.3
  • 28
    • 84872282456 scopus 로고    scopus 로고
    • Impact of the serogroup A meningococcal conjugate vaccine, MenAfriVac, on carriage and herd immunity
    • Kristiansen PA, Diomande F, Ba AK, et al. Impact of the serogroup A meningococcal conjugate vaccine, MenAfriVac, on carriage and herd immunity. Clin Infect Dis 2013; 56:354-363.
    • (2013) Clin Infect Dis , vol.56 , pp. 354-363
    • Kristiansen, P.A.1    Diomande, F.2    Ba, A.K.3
  • 29
    • 84857238470 scopus 로고    scopus 로고
    • Immunogenicity and tolerability of a multicomponent meningococcal serogroup B (4CMenB) vaccine in healthy adolescents in Chile: A phase 2b/3 randomised, observer-blind, placebo-controlled study
    • Santolaya ME, O'Ryan ML, Valenzuela MT, et al. Immunogenicity and tolerability of a multicomponent meningococcal serogroup B (4CMenB) vaccine in healthy adolescents in Chile: a phase 2b/3 randomised, observer-blind, placebo-controlled study. Lancet 2012; 379:617-624.
    • (2012) Lancet , vol.379 , pp. 617-624
    • Santolaya, M.E.1    O'Ryan, M.L.2    Valenzuela, M.T.3
  • 30
    • 84856773073 scopus 로고    scopus 로고
    • Immunogenicity and tolerability of recombinant serogroup B meningococcal vaccine administered with or without routine infant vaccinations according to different immunization schedules: A randomized controlled trial
    • Gossger N, Snape MD, Yu LM, et al. Immunogenicity and tolerability of recombinant serogroup B meningococcal vaccine administered with or without routine infant vaccinations according to different immunization schedules: a randomized controlled trial. J Am Med Assoc 2012; 307:573-582.
    • (2012) J Am Med Assoc , vol.307 , pp. 573-582
    • Gossger, N.1    Snape, M.D.2    Yu, L.M.3
  • 31
    • 84865131962 scopus 로고    scopus 로고
    • The burden of serogroup B meningococcal disease
    • van de Beek D. The burden of serogroup B meningococcal disease. Lancet Neurol 2012; 11:743-745.
    • (2012) Lancet Neurol , vol.11 , pp. 743-745
    • Van De Beek, D.1
  • 32
    • 84868578639 scopus 로고    scopus 로고
    • Progress and challenges in bacterial meningitis
    • van de Beek D. Progress and challenges in bacterial meningitis. Lancet 2012; 380:1623-1624.
    • (2012) Lancet , vol.380 , pp. 1623-1624
    • Van De Beek, D.1
  • 33
    • 84868596712 scopus 로고    scopus 로고
    • Dilemmas in the diagnosis of acute community-acquired bacterial meningitis
    • Brouwer MC, Thwaites GE, Tunkel AR, van de Beek D. Dilemmas in the diagnosis of acute community-acquired bacterial meningitis. Lancet 2012; 380:1684-1692.
    • (2012) Lancet , vol.380 , pp. 1684-1692
    • Brouwer, M.C.1    Thwaites, G.E.2    Tunkel, A.R.3    Van De Beek, D.4
  • 34
    • 66449092115 scopus 로고    scopus 로고
    • A systematic review on clinical benefits of continuous administration of beta-lactam antibiotics
    • Roberts JA, Webb S, Paterson D, et al. A systematic review on clinical benefits of continuous administration of beta-lactam antibiotics. Crit Care Med 2009; 37:2071-2078.
    • (2009) Crit Care Med , vol.37 , pp. 2071-2078
    • Roberts, J.A.1    Webb, S.2    Paterson, D.3
  • 35
    • 84871758823 scopus 로고    scopus 로고
    • Continuous infusion of beta-lactam antibiotics in severe sepsis: A multicenter double-blind, randomized controlled trial
    • Dulhunty JM, Roberts JA, Davis JS, et al. Continuous infusion of beta-lactam antibiotics in severe sepsis: a multicenter double-blind, randomized controlled trial. Clin Infect Dis 2013; 56:236-244.
    • (2013) Clin Infect Dis , vol.56 , pp. 236-244
    • Dulhunty, J.M.1    Roberts, J.A.2    Davis, J.S.3
  • 36
    • 79960697738 scopus 로고    scopus 로고
    • Slow initial beta-lactam infusion and oral paracetamol to treat childhood bacterial meningitis: A randomised, controlled trial
    • Pelkonen T, Roine I, Cruzeiro ML, et al. Slow initial beta-lactam infusion and oral paracetamol to treat childhood bacterial meningitis: a randomised, controlled trial. Lancet Infect Dis 2011; 11:613-621.
    • (2011) Lancet Infect Dis , vol.11 , pp. 613-621
    • Pelkonen, T.1    Roine, I.2    Cruzeiro, M.L.3
  • 37
    • 79957799324 scopus 로고    scopus 로고
    • 5 versus 10 days of treatment with ceftriaxone for bacterial meningitis in children: A double-blind randomised equivalence study
    • Molyneux E, Nizami SQ, Saha S, et al. 5 versus 10 days of treatment with ceftriaxone for bacterial meningitis in children: a double-blind randomised equivalence study. Lancet 2011; 377:1837-1845.
    • (2011) Lancet , vol.377 , pp. 1837-1845
    • Molyneux, E.1    Nizami, S.Q.2    Saha, S.3
  • 38
    • 84877701853 scopus 로고    scopus 로고
    • U.S. National Institutes of Health, trial register
    • U.S. National Institutes of Health, trial register. http://www. clinicaltrials.gov.
  • 40
    • 77954616695 scopus 로고    scopus 로고
    • Management of bacterial meningitis and meningococcal septicaemia in children and young people: Summary of NICE guidance
    • Visintin C, Mugglestone MA, Fields EJ, et al. Management of bacterial meningitis and meningococcal septicaemia in children and young people: summary of NICE guidance. Br Med J 2010; 340:c3209.
    • (2010) Br Med J , vol.340
    • Visintin, C.1    Mugglestone, M.A.2    Fields, E.J.3
  • 41
    • 79957850645 scopus 로고    scopus 로고
    • Fine with five? Shorter antibiotic courses for childhood meningitis
    • Snape MD, Kelly DF. Fine with five? Shorter antibiotic courses for childhood meningitis. Lancet 2011; 377:1809-1810.
    • (2011) Lancet , vol.377 , pp. 1809-1810
    • Snape, M.D.1    Kelly, D.F.2
  • 42
    • 0037079004 scopus 로고    scopus 로고
    • Dexamethasone in adults with bacterial meningitis
    • DOI 10.1056/NEJMoa021334
    • de Gans J, van de Beek D. Dexamethasone in adults with bacterial meningitis. N Engl J Med 2002; 347:1549-1556. (Pubitemid 35315835)
    • (2002) New England Journal of Medicine , vol.347 , Issue.20 , pp. 1549-1556
    • De Gans, J.1    Van Beek, D.2
  • 43
    • 84871298475 scopus 로고    scopus 로고
    • Dexamethasone and long-term survival in bacterial meningitis
    • Fritz D, Brouwer MC, van de Beek D. Dexamethasone and long-term survival in bacterial meningitis. Neurology 2012; 79:2177-2179.
    • (2012) Neurology , vol.79 , pp. 2177-2179
    • Fritz, D.1    Brouwer, M.C.2    Van De Beek, D.3
  • 48
    • 76449121189 scopus 로고    scopus 로고
    • Adjunctive dexamethasone in bacterial meningitis: A meta-analysis of individual patient data
    • van de Beek D, Farrar JJ, de Gans J, et al. Adjunctive dexamethasone in bacterial meningitis: a meta-analysis of individual patient data. Lancet Neurol 2010; 9:254-263.
    • (2010) Lancet Neurol , vol.9 , pp. 254-263
    • Van De Beek, D.1    Farrar, J.J.2    De Gans, J.3
  • 50
    • 39049156422 scopus 로고    scopus 로고
    • Drug Insight: Steroids in CNS infectious diseases - New indications for an old therapy
    • DOI 10.1038/ncpneuro0713, PII NCPNEURO0713
    • Fitch MT, van de Beek D. Drug insight: steroids in CNS infectious diseases: new indications for an old therapy. Nat Clin Pract Neurol 2008; 4:97-104. (Pubitemid 351248067)
    • (2008) Nature Clinical Practice Neurology , vol.4 , Issue.2 , pp. 97-104
    • Fitch, M.T.1    Van De Beek, D.2
  • 51
    • 78149254805 scopus 로고    scopus 로고
    • Nationwide implementation of adjunctive dexamethasone therapy for pneumococcal meningitis
    • Brouwer MC, Heckenberg SG, de Gans J, et al. Nationwide implementation of adjunctive dexamethasone therapy for pneumococcal meningitis. Neurology 2010; 75:1533-1539.
    • (2010) Neurology , vol.75 , pp. 1533-1539
    • Brouwer, M.C.1    Heckenberg, S.G.2    De Gans, J.3
  • 52
    • 77950439307 scopus 로고    scopus 로고
    • Adjuvant glycerol is not beneficial in experimental pneumococcal meningitis
    • Blaser C, Klein M, Grandgirard D, et al. Adjuvant glycerol is not beneficial in experimental pneumococcal meningitis. BMC Infect Dis 2010; 10:84.
    • (2010) BMC Infect Dis , vol.10 , pp. 84
    • Blaser, C.1    Klein, M.2    Grandgirard, D.3
  • 55
    • 0032436388 scopus 로고    scopus 로고
    • Factors associated with improved outcome of Pseudomonas aeruginosa bacteremia in a Finnish university hospital
    • DOI 10.1007/s100960050164
    • Kuikka A, Valtonen VV. Factors associated with improved outcome of Pseudomonas aeruginosa bacteremia in a Finnish university hospital. Eur J Clin Microbiol Infect Dis 1998; 17:701-708. (Pubitemid 29218992)
    • (1998) European Journal of Clinical Microbiology and Infectious Diseases , vol.17 , Issue.10 , pp. 701-708
    • Kuikka, A.1    Valtonen, V.V.2
  • 58
    • 77956521265 scopus 로고    scopus 로고
    • Genetic influences on incidence and case-fatality of infectious disease
    • Petersen L, Andersen PK, Sorensen TI. Genetic influences on incidence and case-fatality of infectious disease. PLoS One 2010; 5:e10603.
    • (2010) PLoS One , vol.5
    • Petersen, L.1    Andersen, P.K.2    Sorensen, T.I.3
  • 60
    • 57449083382 scopus 로고    scopus 로고
    • Host genetic susceptibility to pneumococcal and meningococcal disease: A systematic review and metaanalysis
    • Brouwer MC, de Gans J, Heckenberg SG, et al. Host genetic susceptibility to pneumococcal and meningococcal disease: a systematic review and metaanalysis. Lancet Infect Dis 2009; 9:31-44.
    • (2009) Lancet Infect Dis , vol.9 , pp. 31-44
    • Brouwer, M.C.1    De Gans, J.2    Heckenberg, S.G.3
  • 61
    • 77949545788 scopus 로고    scopus 로고
    • Host genetics and outcome in meningococcal disease: A systematic review and meta-analysis
    • Brouwer MC, Read RC, van de Beek D. Host genetics and outcome in meningococcal disease: a systematic review and meta-analysis. Lancet Infect Dis 2010; 10:262-274.
    • (2010) Lancet Infect Dis , vol.10 , pp. 262-274
    • Brouwer, M.C.1    Read, R.C.2    Van De Beek, D.3
  • 62
    • 84857190262 scopus 로고    scopus 로고
    • Human genetic susceptibility to infectious disease
    • Chapman SJ, Hill AV. Human genetic susceptibility to infectious disease. Nat Rev Genet 2012; 13:175-188.
    • (2012) Nat Rev Genet , vol.13 , pp. 175-188
    • Chapman, S.J.1    Hill, A.V.2
  • 63
    • 79951828121 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in TLR9 are highly associated with susceptibility to bacterial meningitis in children
    • Sanders MS, van Well GT, Ouburg S, et al. Single nucleotide polymorphisms in TLR9 are highly associated with susceptibility to bacterial meningitis in children. Clin Infect Dis 2011; 52:475-480.
    • (2011) Clin Infect Dis , vol.52 , pp. 475-480
    • Sanders, M.S.1    Van Well, G.T.2    Ouburg, S.3
  • 65
    • 79251604801 scopus 로고    scopus 로고
    • Association of macrophage migration inhibitory factor (MIF) polymorphisms with risk of meningitis from Streptococcus pneumoniae
    • Doernberg S, Schaaf B, Dalhoff K, et al. Association of macrophage migration inhibitory factor (MIF) polymorphisms with risk of meningitis from Streptococcus pneumoniae. Cytokine 2011; 53:292-294.
    • (2011) Cytokine , vol.53 , pp. 292-294
    • Doernberg, S.1    Schaaf, B.2    Dalhoff, K.3
  • 66
    • 84872314640 scopus 로고    scopus 로고
    • Genetic variation in inflammasome genes is associated with outcome in bacterial meningitis
    • Geldhoff M, Mook-Kanamori BB, Brouwer MC, et al. Genetic variation in inflammasome genes is associated with outcome in bacterial meningitis. Immunogenetics 2013; 65:9-16.
    • (2013) Immunogenetics , vol.65 , pp. 9-16
    • Geldhoff, M.1    Mook-Kanamori, B.B.2    Brouwer, M.C.3
  • 67
    • 34748819371 scopus 로고    scopus 로고
    • Variation in complement factor 3 is associated with risk of age-related macular degeneration
    • DOI 10.1038/ng2131, PII NG2131
    • Maller JB, Fagerness JA, Reynolds RC, et al. Variation in complement factor 3 is associated with risk of age-related macular degeneration. Nat Genet 2007; 39:1200-1201. (Pubitemid 47482689)
    • (2007) Nature Genetics , vol.39 , Issue.10 , pp. 1200-1201
    • Maller, J.B.1    Fagerness, J.A.2    Reynolds, R.C.3    Neale, B.M.4    Daly, M.J.5    Seddon, J.M.6
  • 68
    • 79957691055 scopus 로고    scopus 로고
    • Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk
    • Heurich M, Martinez-Barricarte R, Francis NJ, et al. Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk. Proc Natl Acad Sci USA 2011; 108:8761-8766.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 8761-8766
    • Heurich, M.1    Martinez-Barricarte, R.2    Francis, N.J.3
  • 69
    • 78650476918 scopus 로고    scopus 로고
    • Meningococcus hijacks a beta2-adrenoceptor/beta-Arrestin pathway to cross brain microvasculature endothelium
    • Coureuil M, Lecuyer H, Scott MG, et al. Meningococcus hijacks a beta2-adrenoceptor/beta-Arrestin pathway to cross brain microvasculature endothelium. Cell 2010; 143:1149-1160.
    • (2010) Cell , vol.143 , pp. 1149-1160
    • Coureuil, M.1    Lecuyer, H.2    Scott, M.G.3
  • 70
    • 80053370268 scopus 로고    scopus 로고
    • Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma
    • Tantisira KG, Lasky-Su J, Harada M, et al. Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma. N Engl J Med 2011; 365:1173-1183.
    • (2011) N Engl J Med , vol.365 , pp. 1173-1183
    • Tantisira, K.G.1    Lasky-Su, J.2    Harada, M.3
  • 72
    • 81455154929 scopus 로고    scopus 로고
    • The NLRP3 inflammasome contributes to brain injury in pneumococcal meningitis and is activated through ATP-dependent lysosomal cathepsin B release
    • Hoegen T, Tremel N, Klein M, et al. The NLRP3 inflammasome contributes to brain injury in pneumococcal meningitis and is activated through ATP-dependent lysosomal cathepsin B release. J Immunol 2011; 187:5440-5451.
    • (2011) J Immunol , vol.187 , pp. 5440-5451
    • Hoegen, T.1    Tremel, N.2    Klein, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.