Urinary trypsin inhibitor protects against liver injury and coagulation pathway dysregulation induced by lipopolysaccharide/D-galactosamine in mice

Laboratory Investigation

Volumn 89, Issue 7, 2009, Pages 833-839

  Takano, Hirohisa ^a,b   Inoue, Ken Ichiro ^a   Shimada, Akinori ^c   Sato, Hiroyuki ^d   Yanagisawa, Rie ^a   Yoshikawa, Toshikazu ^b  

^a NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^c TOTTORI UNIVERSITY   (Japan)

^d MOCHIDA PHARMACEUTICAL CO   (Japan)

Author keywords

D Galactosamine; Disseminated intravascular coagulation; Lipopolysaccharide; Liver injury; Urinary trypsin inhibitor

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; FIBRINOGEN; GALACTOSAMINE; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; PROTHROMBIN; THROMBOPLASTIN; TUMOR NECROSIS FACTOR ALPHA; ULINASTATIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD CELL COUNT; BLOOD CLOTTING DISORDER; CONTROLLED STUDY; DRUG ACTIVITY; FIBRINOLYSIS; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LIVER HEMORRHAGE; LIVER INJURY; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; PROTHROMBIN TIME; THROMBOCYTE COUNT;

ALANINE TRANSAMINASE; ANIMALS; APOPTOSIS; ASPARTATE AMINOTRANSFERASES; DISSEMINATED INTRAVASCULAR COAGULATION; FIBRINOLYSIS; GALACTOSAMINE; GLYCOPROTEINS; HUMANS; INTERFERON-GAMMA; LIPOPOLYSACCHARIDES; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; TUMOR NECROSIS FACTOR-ALPHA;

EID: 67649875342     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2009.35     Document Type: Article

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