Maximal adjuvant activity of nasally delivered IL-1α requires adjuvant-responsive CD11c + cells and does not correlate with adjuvant-induced in vivo cytokine production

Journal of Immunology

Volumn 188, Issue 6, 2012, Pages 2834-2846

  Thompson, Afton L ^a   Johnson, Brandi T ^a   Sempowski, Gregory D ^a,b   Gunn, Michael D ^a,b   Hou, Baidong ^c   DeFranco, Anthony L ^d   Staats, Herman F ^a,b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c INSTITUTE OF BIOPHYSICS   (China)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOATTRACTANT; CHEMOKINE; CYTOKINE; GLYCOPROTEIN P 15095; GRANULOCYTE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G2C; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 13; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTRALIZING ANTIBODY; RECOMBINANT INTERLEUKIN 1ALPHA; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; ADJUVANT THERAPY; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL COMPARTMENTALIZATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DRUG MECHANISM; ENZYME ACTIVATION; FEMALE; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN PRODUCTION; IN VIVO STUDY; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; STROMA CELL; VACCINATION; WILD TYPE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGENS, BACTERIAL; ANTIGENS, CD11C; BACTERIAL TOXINS; CELL SEPARATION; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; IMMUNITY, MUCOSAL; INTERLEUKIN-1ALPHA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; RADIATION CHIMERA; VACCINATION;

EID: 84857823725     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1100254     Document Type: Article

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