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Volumn 6, Issue 3, 2013, Pages 223-225

A call to ARMs: The promise of immunomodulatory small molecules

Author keywords

antibody; antibody recruiting molecules; immunomodulator; immunotherapy; small molecule; synthetic immunology

Indexed keywords

ANTIBODY RECRUITING MOLECULE; BISPECIFIC ANTIBODY; MONOCLONAL ANTIBODY; SMALL MOLECULE TRANSPORT AGENT; TRASTUZUMAB; UNCLASSIFIED DRUG;

EID: 84877615286     PISSN: 17512433     EISSN: 17512441     Source Type: Journal    
DOI: 10.1586/ecp.13.10     Document Type: Review
Times cited : (5)

References (20)
  • 1
    • 77956690413 scopus 로고    scopus 로고
    • Biopharmaceutical benchmarks 2010
    • Walsh G. Biopharmaceutical benchmarks 2010. Nat. Biotechnol. 28(9), 917-924 (2010).
    • (2010) Nat. Biotechnol. , vol.28 , Issue.9 , pp. 917-924
    • Walsh, G.1
  • 2
    • 70449726880 scopus 로고    scopus 로고
    • Market watch: Sales of biologics to show robust growth through to 2013
    • Goodman M. Market watch: sales of biologics to show robust growth through to 2013. Nat. Rev. Drug Discov. 8(11), 837 (2009).
    • (2009) Nat. Rev. Drug Discov. , vol.8 , Issue.11 , pp. 837
    • Goodman, M.1
  • 3
    • 84860896956 scopus 로고    scopus 로고
    • Marketed therapeutic antibodies compendium
    • Reichert JM. Marketed therapeutic antibodies compendium. MAbs 4(3), 413-415 (2012).
    • (2012) MAbs , vol.4 , Issue.3 , pp. 413-415
    • Reichert, J.M.1
  • 4
    • 84872858296 scopus 로고    scopus 로고
    • Which are the antibodies to watch in 2013?
    • Reichert JMWhich are the antibodies to watch in 2013? MAbs 5(1), 1-4 (2013).
    • (2013) MAbs , vol.5 , Issue.1 , pp. 1-4
    • Reichert, J.M.1
  • 5
    • 84957942752 scopus 로고    scopus 로고
    • Current and experimental antibodybased therapeutics: Insights, breakthroughs, setbacks and future directions
    • Murad JP, Lin OA, Espinosa EV, Khasawneh FT. Current and experimental antibodybased therapeutics: insights, breakthroughs, setbacks and future directions. Curr. Mol. Med. 13(1), 165-178 (2013).
    • (2013) Curr. Mol. Med. , vol.13 , Issue.1 , pp. 165-178
    • Murad, J.P.1    Lin, O.A.2    Espinosa, E.V.3    Khasawneh, F.T.4
  • 6
    • 0036781811 scopus 로고    scopus 로고
    • Ligand-targeted therapeutics in anticancer therapy
    • Allen TM. Ligand-targeted therapeutics in anticancer therapy. Nat. Rev. Cancer 2(10), 750-763 (2002).
    • (2002) Nat. Rev. Cancer , vol.2 , Issue.10 , pp. 750-763
    • Allen, T.M.1
  • 7
    • 0028322369 scopus 로고
    • New approaches for the development and application of monoclonal antibodies for the diagnosis and therapy of human cancer
    • Leon JA, Goldstein NI, Fisher PB. New approaches for the development and application of monoclonal antibodies for the diagnosis and therapy of human cancer. Pharmacol. Ther. 61(1-2), 237-278 (1994).
    • (1994) Pharmacol. Ther. , vol.61 , Issue.1-2 , pp. 237-278
    • Leon, J.A.1    Goldstein, N.I.2    Fisher, P.B.3
  • 8
    • 33747616656 scopus 로고    scopus 로고
    • Engineering of therapeutic antibodies to minimize immunogenicity and optimize function
    • Presta LG. Engineering of therapeutic antibodies to minimize immunogenicity and optimize function. Adv. Drug Deliv. Rev. 58(5-6), 640-656 (2006).
    • (2006) Adv. Drug Deliv. Rev. , vol.58 , Issue.5-6 , pp. 640-656
    • Presta, L.G.1
  • 9
    • 33747855481 scopus 로고    scopus 로고
    • Comparing antibody and small-molecule therapies for cancer
    • Imai K, Takaoka A. Comparing antibody and small-molecule therapies for cancer. Nat. Rev. Cancer 6(9), 714-727 (2006).
    • (2006) Nat. Rev. Cancer , vol.6 , Issue.9 , pp. 714-727
    • Imai, K.1    Takaoka, A.2
  • 10
  • 11
    • 9444260479 scopus 로고    scopus 로고
    • Biological impediments to monoclonal antibody-based cancer immunotherapy
    • Christiansen J, Rajasekaran AK. Biological impediments to monoclonal antibody-based cancer immunotherapy. Mol. Cancer Ther. 3(11), 1493-1501 (2004).
    • (2004) Mol. Cancer Ther. , vol.3 , Issue.11 , pp. 1493-1501
    • Christiansen, J.1    Rajasekaran, A.K.2
  • 12
    • 33644845334 scopus 로고    scopus 로고
    • GlaxoSmithKline cancer drug threatens Herceptin market
    • Waltz E. GlaxoSmithKline cancer drug threatens Herceptin market. Nat. Biotechnol. 23(12), 1453-1454 (2005).
    • (2005) Nat. Biotechnol. , vol.23 , Issue.12 , pp. 1453-1454
    • Waltz, E.1
  • 13
    • 84867702136 scopus 로고    scopus 로고
    • Novel protein scaffolds as emerging therapeutic proteins: From discovery to clinical proof-of-concept
    • Wurch T, Pierré A, Depil S. Novel protein scaffolds as emerging therapeutic proteins: from discovery to clinical proof-of-concept. Trends Biotechnol. 30(11), 575-582 (2012).
    • (2012) Trends Biotechnol. , vol.30 , Issue.11 , pp. 575-582
    • Wurch, T.1    Pierré, A.2    Depil, S.3
  • 14
    • 84864133677 scopus 로고    scopus 로고
    • Antibody-recruiting molecules: An emerging paradigm for engaging immune function in treating human disease
    • McEnaney PJ, Parker CG, Zhang AX, Spiegel DA. Antibody-recruiting molecules: an emerging paradigm for engaging immune function in treating human disease. ACS Chem. Biol. 7(7), 1139-1151 (2012).
    • (2012) ACS Chem. Biol. , vol.7 , Issue.7 , pp. 1139-1151
    • McEnaney, P.J.1    Parker, C.G.2    Zhang, A.X.3    Spiegel, D.A.4
  • 15
    • 27144550160 scopus 로고    scopus 로고
    • Arming antibodies: Prospects and challenges for immunoconjugates
    • Wu AM, Senter PD. Arming antibodies: prospects and challenges for immunoconjugates. Nat. Biotechnol. 23(9), 1137-1146 (2005).
    • (2005) Nat. Biotechnol. , vol.23 , Issue.9 , pp. 1137-1146
    • Wu, A.M.1    Senter, P.D.2
  • 16
    • 33747855481 scopus 로고    scopus 로고
    • Comparing antibody and small-molecule therapies for cancer
    • Imai K, Takaoka A. Comparing antibody and small-molecule therapies for cancer. Nat. Rev. Cancer 6(9), 714-727 (2006).
    • (2006) Nat. Rev. Cancer , vol.6 , Issue.9 , pp. 714-727
    • Imai, K.1    Takaoka, A.2
  • 18
    • 79952271693 scopus 로고    scopus 로고
    • Specifically targeting angiopoietin-2 inhibits angiogenesis. Tie2-expressing monocyte infiltration, and tumor growth
    • Huang H, Lai JY, Do J et al. Specifically targeting angiopoietin-2 inhibits angiogenesis, Tie2-expressing monocyte infiltration, and tumor growth. Clin. Cancer Res. 17(5), 1001-1011 (2011).
    • (2011) Clin. Cancer Res. , vol.17 , Issue.5 , pp. 1001-1011
    • Huang, H.1    Lai, J.Y.2    Do, J.3
  • 19
    • 67849084593 scopus 로고    scopus 로고
    • Protein binding: Antibody surrogates click into place
    • Kodadek T. Protein binding: antibody surrogates click into place. Nat. Chem. 1(3), 183-185 (2009).
    • (2009) Nat. Chem. , vol.1 , Issue.3 , pp. 183-185
    • Kodadek, T.1
  • 20
    • 70349286700 scopus 로고    scopus 로고
    • Profiling human serum antibodies with a carbohydrate antigen microarray
    • Oyelaran O, McShane LM, Dodd L, Gildersleeve JC. Profiling human serum antibodies with a carbohydrate antigen microarray. J. Proteome Res. 8(9), 4301-4310 (2009).
    • (2009) J. Proteome Res. , vol.8 , Issue.9 , pp. 4301-4310
    • Oyelaran, O.1    McShane, L.M.2    Dodd, L.3    Gildersleeve, J.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.