AMPK inhibition enhances apoptosis in MLL-rearranged pediatric B-acute lymphoblastic leukemia cells

Leukemia

Volumn 27, Issue 5, 2013, Pages 1019-1027

  Accordi, B ^a   Galla, L ^a   Milani, G ^a   Curtarello, M ^b   Serafin, V ^a   Lissandron, V ^a   Viola, G ^a   Te Kronnie, G ^a   De Maria, R ^c   Petricoin, E F ^d   Liotta, L A ^d   Indraccolo, S ^b   Basso, G ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b VENETO INSTITUTE OF ONCOLOGY IOV IRCCS   (Italy)

^c ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^d GEORGE MASON UNIVERSITY   (United States)

Author keywords

acute lymphoblastic leukemia; AMPK; apoptosis; MLL rearrangements

Indexed keywords

AMP ACTIVATED PROTEIN KINASE INHIBITOR; ARACTYN; ASPARAGINASE; CASPASE; CYTARABINE; CYTOCHROME C; DAUNORUBICIN; DEXAMETHASONE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MIXED LINEAGE LEUKEMIA PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN KINASE INHIBITOR; REACTIVE OXYGEN METABOLITE; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; VINCRISTINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CELL SURVIVAL; CHILDHOOD LEUKEMIA; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; DRUG TARGETING; ENZYME INHIBITION; ENZYME RELEASE; GENE; GENE REARRANGEMENT; GROWTH INHIBITION; HUMAN; HUMAN CELL; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; MLL GENE; PRIORITY JOURNAL;

AMP-ACTIVATED PROTEIN KINASES; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; GENE REARRANGEMENT; HUMANS; MITOCHONDRIA; MYELOID-LYMPHOID LEUKEMIA PROTEIN; PRECURSOR B-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PYRAZOLES; PYRIMIDINES;

EID: 84877614687     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2012.338     Document Type: Article

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