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Volumn 6, Issue 4, 2013, Pages 239-251

The effect of vascular endothelial growth factor in the progression of bladder cancer and diabetic retinopathy

Author keywords

Bladder cancer; Diabetic retinopathy; Progression; Vascular endothelial growth factor (VEGF)

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; BEVACIZUMAB; HYPOXIA INDUCIBLE FACTOR 1; NICOTINE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; POLYCYCLIC AROMATIC HYDROCARBON; PROTEIN KINASE B; PROTEIN KINASE C; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; VASCULOTROPIN; VASCULOTROPIN A; VASCULOTROPIN B; VASCULOTROPIN C; VASCULOTROPIN D; VASCULOTROPIN RECEPTOR; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; VASCULOTROPIN RECEPTOR 3;

EID: 84877613151     PISSN: None     EISSN: 19405901     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (50)

References (144)
  • 1
    • 1842786020 scopus 로고    scopus 로고
    • Gender, racial and age differences in bladder cancer incidence and mortality
    • Madeb R and Meesing EM. Gender, racial and age differences in bladder cancer incidence and mortality. Urol Oncol 2004; 22: 86-92.
    • (2004) Urol Oncol , vol.22 , pp. 86-92
    • Madeb, R.1    Meesing, E.M.2
  • 3
    • 84873452824 scopus 로고    scopus 로고
    • Oncogenic Activation of Pak1-Dependent Pathway of Macropinocytosis Determines BCG Entry into Bladder Cancer Cells
    • Redelman S, Gil I, Gopa S, David BG and Michael S. Oncogenic Activation of Pak1-Dependent Pathway of Macropinocytosis Determines BCG Entry into Bladder Cancer Cells. Cancer Res 2013; 73: 1156-67.
    • (2013) Cancer Res , vol.73 , pp. 1156-1167
    • Redelman, S.1    Gil, I.2    Gopa, S.3    David, B.G.4    Michael, S.5
  • 4
    • 78649754716 scopus 로고    scopus 로고
    • Genetic aberrations of the K-RAS proto-oncogene in bladder cancer in Kashmiri population
    • Nanda MS, Sameer AS, Syeed N, Shah ZA, Murtaza I, Siddiqi MA, Ali A. Genetic aberrations of the K-RAS proto-oncogene in bladder cancer in Kashmiri population. Urol J 2010; 7: 168-173.
    • (2010) Urol J , vol.7 , pp. 168-173
    • Nanda, M.S.1    Sameer, A.S.2    Syeed, N.3    Shah, Z.A.4    Murtaza, I.5    Siddiqi, M.A.6    Ali, A.7
  • 7
    • 84861205345 scopus 로고    scopus 로고
    • Expressional evaluation of Vascular Endothelial Growth Factor (VEGF) protein in urinary bladder carcinoma patients exposed to cigarette smoke
    • Rahmani A, Alzohairy M, Khadri H, Mandal AK, Rizvi MA. Expressional evaluation of Vascular Endothelial Growth Factor (VEGF) protein in urinary bladder carcinoma patients exposed to cigarette smoke. Int J Clin Exp Pathol 2012; 5: 195-202.
    • (2012) Int J Clin Exp Pathol , vol.5 , pp. 195-202
    • Rahmani, A.1    Alzohairy, M.2    Khadri, H.3    Mandal, A.K.4    Rizvi, M.A.5
  • 8
    • 79961008990 scopus 로고
    • Aplin 2 Paracrine Regulation Of Angiogenesis By Different Cell Types In The Aorta Ring Model
    • Nicosia RF, Zorzi P, Ligresti G, Morishita A and Alfred C. Aplin 2 Paracrine Regulation Of Angiogenesis By Different Cell Types In The Aorta Ring Model. Int J Dev Biol 1994; 55: 447-453.
    • (1994) Int J Dev Biol , vol.55 , pp. 447-453
    • Nicosia, R.F.1    Zorzi, P.2    Ligresti, G.3    Morishita, A.4    Alfred, C.5
  • 9
    • 33747195353 scopus 로고    scopus 로고
    • Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
    • Takahashi K and Yamanaka S. Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors. Cell 2006; 126: 663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 10
    • 0028010940 scopus 로고
    • A minority 01 carcinoma cells producing acidic fibroblast growth factor induces a community effect for tumor progression
    • Jouanneau J, Moens G, Bourgeois Y, Poupon MF and Thiery JP. A minority 01 carcinoma cells producing acidic fibroblast growth factor induces a community effect for tumor progression. Proc Nat Acad Sci 1994; 91: 286-290.
    • (1994) Proc Nat Acad Sci , vol.91 , pp. 286-290
    • Jouanneau, J.1    Moens, G.2    Bourgeois, Y.3    Poupon, M.F.4    Thiery, J.P.5
  • 12
    • 4243735706 scopus 로고    scopus 로고
    • Angiogenesis in embryonic development-a review
    • Breier G. Angiogenesis in embryonic development-a review. Placenta 2000; 21: 11-15.
    • (2000) Placenta , vol.21 , pp. 11-15
    • Breier, G.1
  • 13
    • 0033855011 scopus 로고    scopus 로고
    • Endothelial signal integration in vascular assembly
    • Daniel TO and Abrahamson D. Endothelial signal integration in vascular assembly. Ann Rev Physiol 2000; 62: 649-671.
    • (2000) Ann Rev Physiol , vol.62 , pp. 649-671
    • Daniel, T.O.1    Abrahamson, D.2
  • 15
    • 0028865183 scopus 로고
    • The pathophysiology of angiogenesis
    • Polverini PJ. The pathophysiology of angiogenesis. Crit Rev Oral Biol Med 1995; 6: 230-247.
    • (1995) Crit Rev Oral Biol Med , vol.6 , pp. 230-247
    • Polverini, P.J.1
  • 17
    • 0028961523 scopus 로고
    • Different Angiogenic Pathways Characterize Superficial and Invasive Bladder Cancer
    • O'Brien T, Cranston D, Fuggle S, Bicknell R and Harris AL. Different Angiogenic Pathways Characterize Superficial and Invasive Bladder Cancer. Cancer Res 1995; 55: 510-513.
    • (1995) Cancer Res , vol.55 , pp. 510-513
    • O'Brien, T.1    Cranston, D.2    Fuggle, S.3    Bicknell, R.4    Harris, A.L.5
  • 18
    • 0032557564 scopus 로고    scopus 로고
    • Vascular Endothelial Growth Factor Induces Expression of the Antiapoptotic Proteins Bcl-2 and A1 in Vascular Endothelial Cells
    • Gerber HP, Dixit V and Ferrara N. Vascular Endothelial Growth Factor Induces Expression of the Antiapoptotic Proteins Bcl-2 and A1 in Vascular Endothelial Cells. J Biol Chem1998; 273: 13313-13316.
    • J Biol Chem1998 , vol.273 , pp. 13313-13316
    • Gerber, H.P.1    Dixit, V.2    Ferrara, N.3
  • 19
    • 0032907687 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) and its receptors
    • Neufeld G, Cohen T, Gengrinovitch S and Poltorak Z. Vascular endothelial growth factor (VEGF) and its receptors. FASEB J 1999; 1: 9-22.
    • (1999) FASEB J , vol.1 , pp. 9-22
    • Neufeld, G.1    Cohen, T.2    Gengrinovitch, S.3    Poltorak, Z.4
  • 20
    • 0025999033 scopus 로고
    • The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing
    • Tischer E, Mitchell R, Hartman T, Silva M, Gospodarowicz D, Fiddes JC and Abraham JA. The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing. J Biol Chem 1991; 18: 11947-54.
    • (1991) J Biol Chem , vol.18 , pp. 11947-11954
    • Tischer, E.1    Mitchell, R.2    Hartman, T.3    Silva, M.4    Gospodarowicz, D.5    Fiddes, J.C.6    Abraham, J.A.7
  • 21
    • 0028833699 scopus 로고
    • Structural requirements for dimerization, glycosylation, secretion, and biological function of VPF/VEGF
    • Claffey KP, Senger DR and Spiegelman BM. Structural requirements for dimerization, glycosylation, secretion, and biological function of VPF/VEGF. Biochim Biophys Acta 1995; 1246: 1-9.
    • (1995) Biochim Biophys Acta , vol.1246 , pp. 1-9
    • Claffey, K.P.1    Senger, D.R.2    Spiegelman, B.M.3
  • 23
    • 0029782928 scopus 로고    scopus 로고
    • Genomic organization of the mouse and human genomes for vascular endothelial growth factor B (VEGF-B) and characterization of a second splice form
    • Olofsson B, Pajusola K, von-Euler G, Chilov D, Alitalo K and Eriksson U. Genomic organization of the mouse and human genomes for vascular endothelial growth factor B (VEGF-B) and characterization of a second splice form. J Biol Chem 1996; 271: 19310-19317.
    • (1996) J Biol Chem , vol.271 , pp. 19310-19317
    • Olofsson, B.1    Pajusola, K.2    Von-Euler, G.3    Chilov, D.4    Alitalo, K.5    Eriksson, U.6
  • 24
    • 0034702905 scopus 로고    scopus 로고
    • VEGF gene delivery to myocardium: Deleterious effects of unregulated expression
    • Lee RJ, Springer ML, Blanco-Bose WE and Shaw R. VEGF gene delivery to myocardium: deleterious effects of unregulated expression. Circulation 2000; 102: 898-901.
    • (2000) Circulation , vol.102 , pp. 898-901
    • Lee, R.J.1    Springer, M.L.2    Blanco-Bose, W.E.3    Shaw, R.4
  • 25
    • 33947370773 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) signaling in tumor progression
    • Roskoski R. Vascular endothelial growth factor (VEGF) signaling in tumor progression. Crit Reviews in Oncol/Hematol 2007; 62: 179-213.
    • (2007) Crit Reviews In Oncol/Hematol , vol.62 , pp. 179-213
    • Roskoski, R.1
  • 26
    • 80255124778 scopus 로고    scopus 로고
    • Roles of VEGF-C and Smad4 in the lymphangiogenesis, lymphatic metastasis, and prognosis in colon cancer
    • Li X, Liu B, Xiao J, Yuan Y, Ma J, Zhang Y. Roles of VEGF-C and Smad4 in the lymphangiogenesis, lymphatic metastasis, and prognosis in colon cancer. J Gastrointest Surg 2011; 15: 2001-2010.
    • (2011) J Gastrointest Surg , vol.15 , pp. 2001-2010
    • Li, X.1    Liu, B.2    Xiao, J.3    Yuan, Y.4    Ma, J.5    Zhang, Y.6
  • 28
    • 33644790059 scopus 로고    scopus 로고
    • Increased expressions of vascular endothelial growth factor (VEGF), VEGF-C and VEGF receptor-3 in prostate cancer tissue are associated with tumor progression
    • Yang J, Wu HF, Qian LX, Zhang W, Hua LX, Yu ML, Wang Z, Xu ZQ, Sui YG, Wang XR. Increased expressions of vascular endothelial growth factor (VEGF), VEGF-C and VEGF receptor-3 in prostate cancer tissue are associated with tumor progression. Asian J Androl 2006; 8: 169-175.
    • (2006) Asian J Androl , vol.8 , pp. 169-175
    • Yang, J.1    Wu, H.F.2    Qian, L.X.3    Zhang, W.4    Hua, L.X.5    Yu, M.L.6    Wang, Z.7    Xu, Z.Q.8    Sui, Y.G.9    Wang, X.R.10
  • 29
    • 79251584963 scopus 로고    scopus 로고
    • Expressions of COX-2 and VEGF-C in gastric cancer: Correlations with lymphangiogenesis and prognostic implications
    • Gou HF, Chen XC, Zhu J, Jiang M, Yang Y, Cao D, ou M. Expressions of COX-2 and VEGF-C in gastric cancer: correlations with lymphangiogenesis and prognostic implications. J Exp Clin Cancer Res 2011; 30: 14.
    • (2011) J Exp Clin Cancer Res , vol.30 , pp. 14
    • Gou, H.F.1    Chen, X.C.2    Zhu, J.3    Jiang, M.4    Yang, Y.5    Cao, D.6    Ou, M.7
  • 30
    • 65249113902 scopus 로고    scopus 로고
    • Prognostic significance of VEGF-C expression in correlation with COX-2, lymphatic microvessel density, and clinicopathologic characteristics in human non-small cell lung cancer
    • Guo X, Chen Y, Xu Z, Qian Y and Yu X. Prognostic significance of VEGF-C expression in correlation with COX-2, lymphatic microvessel density, and clinicopathologic characteristics in human non-small cell lung cancer. Acta Biochim Biophys Sin (Shanghai) 2009; 41: 217-222.
    • (2009) Acta Biochim Biophys Sin (Shanghai) , vol.41 , pp. 217-222
    • Guo, X.1    Chen, Y.2    Xu, Z.3    Qian, Y.4    Yu, X.5
  • 31
    • 0031905861 scopus 로고    scopus 로고
    • Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)
    • Achen MG, Jeltsch M, Kukk E, Makinen T, Vitali A, Wilks AF, Alitalo K and Stacker SA. Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4). Proc Natl Acad Sci 1998; 2: 548-553.
    • (1998) Proc Natl Acad Sci , vol.2 , pp. 548-553
    • Achen, M.G.1    Jeltsch, M.2    Kukk, E.3    Makinen, T.4    Vitali, A.5    Wilks, A.F.6    Alitalo, K.7    Stacker, S.A.8
  • 34
    • 0031570672 scopus 로고    scopus 로고
    • Molecular cloning of a novel vascular endothelial growth factor, VEGF-D
    • Yamada Y, Jo N, Shimane M and Hirata Y. Molecular cloning of a novel vascular endothelial growth factor, VEGF-D. Genomics 1997; 42: 483-488.
    • (1997) Genomics , vol.42 , pp. 483-488
    • Yamada, Y.1    Jo, N.2    Shimane, M.3    Hirata, Y.4
  • 36
    • 0035052854 scopus 로고    scopus 로고
    • Novel VEGF family members: VEGF-B, VEGF-C and VEGF-D
    • Li X and Eriksson U. Novel VEGF family members: VEGF-B, VEGF-C and VEGF-D. Int J Biochem Cell Biol 2001; 33: 421-426
    • (2001) Int J Biochem Cell Biol , vol.33 , pp. 421-426
    • Li, X.1    Eriksson, U.2
  • 37
    • 70350780365 scopus 로고    scopus 로고
    • Structure and function of VEGF receptors
    • Stuttfeld E and Ballmer-Hofer K. Structure and function of VEGF receptors. IUBMB Life 2009; 61: 915-22.
    • (2009) IUBMB Life , vol.61 , pp. 915-922
    • Stuttfeld, E.1    Ballmer-Hofer, K.2
  • 38
    • 34047141776 scopus 로고    scopus 로고
    • Vascular endothelial growth factor family of ligands and receptors: Review
    • Otrock ZK, Makarem JA, Shamseddine AI. Vascular endothelial growth factor family of ligands and receptors: review. Blood Cells Mol Dis 2007; 38: 258-268.
    • (2007) Blood Cells Mol Dis , vol.38 , pp. 258-268
    • Otrock, Z.K.1    Makarem, J.A.2    Shamseddine, A.I.3
  • 40
    • 0036306121 scopus 로고    scopus 로고
    • Vascular growth factors and lymphangiogenesis (Review)
    • Jusila L and Alitalo K. Vascular growth factors and lymphangiogenesis (Review). Physiol Rev 2000; 82: 673-700.
    • (2000) Physiol Rev , vol.82 , pp. 673-700
    • Jusila, L.1    Alitalo, K.2
  • 41
    • 0025259592 scopus 로고
    • Nucleotide sequence and expression of a novel human receptor type tyrosine kinase gene (flt) closely related to the fms family
    • Shibuya M, Yamaguchi S, Yamane A, Ikeda T, Tojo A, Matsushime H, Sato M. Nucleotide sequence and expression of a novel human receptor type tyrosine kinase gene (flt) closely related to the fms family. Oncogene 1990; 5: 519-524.
    • (1990) Oncogene , vol.5 , pp. 519-524
    • Shibuya, M.1    Yamaguchi, S.2    Yamane, A.3    Ikeda, T.4    Tojo, A.5    Matsushime, H.6    Sato, M.7
  • 42
    • 56749174211 scopus 로고    scopus 로고
    • FLT1 and its ligands VEGFB and PlGF: Drug targets for anti-angiogenic therapy?
    • Fischer C, Mazzone M, Jonckx B and Carmeliet P. FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy? Nat Rev Cancer 2008; 8: 942-956.
    • (2008) Nat Rev Cancer , vol.8 , pp. 942-956
    • Fischer, C.1    Mazzone, M.2    Jonckx, B.3    Carmeliet, P.4
  • 43
    • 74549133965 scopus 로고    scopus 로고
    • Autocrine VEGF signaling synergizes with EGFR in tumor cells to promote epithelial cancer development
    • Lichtenberger BM, Tan PK, Niederleithner H, Ferrara N, Petzelbauer P, Sibilia M. Autocrine VEGF signaling synergizes with EGFR in tumor cells to promote epithelial cancer development. Cell 2010; 140: 268-279.
    • (2010) Cell , vol.140 , pp. 268-279
    • Lichtenberger, B.M.1    Tan, P.K.2    Niederleithner, H.3    Ferrara, N.4    Petzelbauer, P.5    Sibilia, M.6
  • 44
    • 33747498714 scopus 로고    scopus 로고
    • The vascular endothelial growth factor receptor (VEGFR-1) supports growth and survival of human breast carcinoma
    • Wu Y, Hooper AT, Zhong Z, Witte L, Bohlen P, Rafii S, Hicklin DJ. The vascular endothelial growth factor receptor (VEGFR-1) supports growth and survival of human breast carcinoma. Int J Cancer 2006; 119: 1519-1529.
    • (2006) Int J Cancer , vol.119 , pp. 1519-1529
    • Wu, Y.1    Hooper, A.T.2    Zhong, Z.3    Witte, L.4    Bohlen, P.5    Rafii, S.6    Hicklin, D.J.7
  • 46
    • 1842293350 scopus 로고    scopus 로고
    • Flk-1 expression defines a population of early embryonic hematopoietic precursors
    • Kabrun N, Buhring HJ, Choi K, Ullrich A, Risau W and Keller G. Flk-1 expression defines a population of early embryonic hematopoietic precursors. Development 1997; 124: 2039-2048.
    • (1997) Development , vol.124 , pp. 2039-2048
    • Kabrun, N.1    Buhring, H.J.2    Choi, K.3    Ullrich, A.4    Risau, W.5    Keller, G.6
  • 48
    • 0035793623 scopus 로고    scopus 로고
    • Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2): A reassessment using novel receptor-specific vascular endothelial growth factor mutants
    • Gille H, Kowalski J, Li B, LeCouter J, Moffat B, Zioncheck TF, Pelletier N, Ferrara N. Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2): a reassessment using novel receptor-specific vascular endothelial growth factor mutants. J Biol Chem 2001; 276: 3222-3230.
    • (2001) J Biol Chem , vol.276 , pp. 3222-3230
    • Gille, H.1    Kowalski, J.2    Li, B.3    Lecouter, J.4    Moffat, B.5    Zioncheck, T.F.6    Pelletier, N.7    Ferrara, N.8
  • 49
    • 0000481740 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Direct neuroprotective effect in in vitro ischemia
    • Jin KL, Mao XO and Greenberg DA. Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia. Proc Natl Acad Sci 2000; 97: 10242-10247.
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 10242-10247
    • Jin, K.L.1    Mao, X.O.2    Greenberg, D.A.3
  • 51
    • 15044350330 scopus 로고    scopus 로고
    • Reduction of a vascular endothelial growth factor receptor, fetal liver kinase-1, by antisense oligonucleotides induces motor neuron death in rat spinal cord exposed to hypoxia
    • Shiote M, Nagano I, Ilieva H, Murakami T, Narai H, Ohta Y, Nagata T, Shoji M, Abe K. Reduction of a vascular endothelial growth factor receptor, fetal liver kinase-1, by antisense oligonucleotides induces motor neuron death in rat spinal cord exposed to hypoxia. Neuroscience 2005; 132: 175-182.
    • (2005) Neuroscience , vol.132 , pp. 175-182
    • Shiote, M.1    Nagano, I.2    Ilieva, H.3    Murakami, T.4    Narai, H.5    Ohta, Y.6    Nagata, T.7    Shoji, M.8    Abe, K.9
  • 52
    • 0029839804 scopus 로고    scopus 로고
    • Flk-1, a receptor for vascular endothelial growth factor (VEGF), is expressed by retinal progenitor cells
    • Yang K and Cepko CL. Flk-1, a receptor for vascular endothelial growth factor (VEGF), is expressed by retinal progenitor cells. J Neurosci 1996; 16: 6089-6099.
    • (1996) J Neurosci , vol.16 , pp. 6089-6099
    • Yang, K.1    Cepko, C.L.2
  • 53
    • 0041561201 scopus 로고    scopus 로고
    • Lymphangiogenic growth factors, receptors and therapies
    • Lohela M, Saaristo A, Veikkola T and Alitalo K. Lymphangiogenic growth factors, receptors and therapies. Thromb Haemost 2003; 90: 167-84.
    • (2003) Thromb Haemost , vol.90 , pp. 167-184
    • Lohela, M.1    Saaristo, A.2    Veikkola, T.3    Alitalo, K.4
  • 54
    • 0028091775 scopus 로고
    • Signalling properties of FLT4, a proteolytically processedreceptor tyrosine kinase related to two VEGF receptors
    • Pajusola K, Aprelikova O, Pelicci G, Weich H, Claesson-Welsh L, Alitalo K. Signalling properties of FLT4, a proteolytically processedreceptor tyrosine kinase related to two VEGF receptors. Oncogene 1994; 9: 3545-55.
    • (1994) Oncogene , vol.9 , pp. 3545-3555
    • Pajusola, K.1    Aprelikova, O.2    Pelicci, G.3    Weich, H.4    Claesson-Welsh, L.5    Alitalo, K.6
  • 55
    • 25144511910 scopus 로고    scopus 로고
    • The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions
    • Takahashi H and Shibuya M. The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions. Clinical Science 2005; 109: 227-241.
    • (2005) Clinical Science , vol.109 , pp. 227-241
    • Takahashi, H.1    Shibuya, M.2
  • 56
    • 12344274486 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factors
    • Tammela T, Enholm B, Alitalo K and Paavone K. The biology of vascular endothelial growth factors. Cardiovas Res 2005; 65: 550-563.
    • (2005) Cardiovas Res , vol.65 , pp. 550-563
    • Tammela, T.1    Enholm, B.2    Alitalo, K.3    Paavone, K.4
  • 58
    • 0033814892 scopus 로고    scopus 로고
    • VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues
    • Partanen TA, Arola J, Saaristo A, Jussila L, Ora A, Miettinen M, Stacker SA, Achen MG, Alitalo K. VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues. FASEB J 2000; 14: 2087-2096.
    • (2000) FASEB J , vol.14 , pp. 2087-2096
    • Partanen, T.A.1    Arola, J.2    Saaristo, A.3    Jussila, L.4    Ora, A.5    Miettinen, M.6    Stacker, S.A.7    Achen, M.G.8    Alitalo, K.9
  • 59
    • 34548443831 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-2: Structure, function, intracellular signalling and therapeutic inhibition
    • Holmes K, Roberts OL, Thomas AM and Cross MJ. Vascular endothelial growth factor receptor-2: Structure, function, intracellular signalling and therapeutic inhibition. Cell Signal 2007 Oct; 19: 2003-12.
    • (2007) Cell Signal , vol.19 , pp. 2003-2012
    • Holmes, K.1    Roberts, O.L.2    Thomas, A.M.3    Cross, M.J.4
  • 60
    • 0037451069 scopus 로고    scopus 로고
    • VEGF-induced activation of the PI3-K/Akt pathway reduces mutant SOD1-mediated motor neuron cell death
    • Li B, Xu W, Luo C, Gozal D, Liu R. VEGF-induced activation of the PI3-K/Akt pathway reduces mutant SOD1-mediated motor neuron cell death. Brain Res Mol Brain Res 2003; 111: 155-64.
    • (2003) Brain Res Mol Brain Res , vol.111 , pp. 155-164
    • Li, B.1    Xu, W.2    Luo, C.3    Gozal, D.4    Liu, R.5
  • 61
    • 0037004171 scopus 로고    scopus 로고
    • Role of phosphatidylinositol 3-kinase/Akt pathway in angiotensin II and insulin-like growth factor-1 modulation of nitric oxide synthase in vascular smooth muscle cells
    • Isenovic ER, Meng Y, Divald A, Milivojevic N and Sowers JR. Role of phosphatidylinositol 3-kinase/Akt pathway in angiotensin II and insulin-like growth factor-1 modulation of nitric oxide synthase in vascular smooth muscle cells. Endocrine 2002; 19: 287-292.
    • (2002) Endocrine , vol.19 , pp. 287-292
    • Isenovic, E.R.1    Meng, Y.2    Divald, A.3    Milivojevic, N.4    Sowers, J.R.5
  • 63
    • 0029047382 scopus 로고
    • Interaction of the Flt-1 tyrosine kinase receptor with the p85 subunit of phosphatidylinositol 3-kinase. Mapping of a novel site involved in binding
    • Cunningham SA, Waxham MN, Arrate PM and Brock TA. Interaction of the Flt-1 tyrosine kinase receptor with the p85 subunit of phosphatidylinositol 3-kinase. Mapping of a novel site involved in binding. J Biol Chem 1995; 270: 20254-20257.
    • (1995) J Biol Chem , vol.270 , pp. 20254-20257
    • Cunningham, S.A.1    Waxham, M.N.2    Arrate, P.M.3    Brock, T.A.4
  • 64
    • 0035947584 scopus 로고    scopus 로고
    • Identification of tyrosine residues in vascular endothelial growth factor receptor-2/FLK-1 involved in activation of phosphatidylinositol 3-kinase and cell proliferation
    • Dayanir V, Meyer RD, Lashkari K, Rahimi N. Identification of tyrosine residues in vascular endothelial growth factor receptor-2/FLK-1 involved in activation of phosphatidylinositol 3-kinase and cell proliferation. J Biol Chem 2001; 276: 17686-17692.
    • (2001) J Biol Chem , vol.276 , pp. 17686-17692
    • Dayanir, V.1    Meyer, R.D.2    Lashkari, K.3    Rahimi, N.4
  • 65
    • 0032189381 scopus 로고    scopus 로고
    • Protein kinase B (c-Akt): A multifunctional mediator of phosphatidylinositol 3-kinase activation
    • Coffer PJ, Jin J and Woodgett JR. Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation. Biochem J 1998; 335: 1-13.
    • (1998) Biochem J , vol.335 , pp. 1-13
    • Coffer, P.J.1    Jin, J.2    Woodgett, J.R.3
  • 66
    • 0033551070 scopus 로고    scopus 로고
    • New insights into tumor suppression: PTEN suppression tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
    • Cantley LC and Neel BG. New insights into tumor suppression: PTEN suppression tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proc Natl Acad Sci 1999; 96: 4240-4245.
    • (1999) Proc Natl Acad Sci , vol.96 , pp. 4240-4245
    • Cantley, L.C.1    Neel, B.G.2
  • 67
    • 0034681264 scopus 로고    scopus 로고
    • The multiple roles of PTEN in tumor suppression
    • Di Cristofano A and Pandolfi PP. The multiple roles of PTEN in tumor suppression. Cell 2000; 100: 387-390.
    • (2000) Cell , vol.100 , pp. 387-390
    • Di, C.A.1    Pandolfi, P.P.2
  • 68
    • 31344479312 scopus 로고    scopus 로고
    • Phosphorylated Akt overexpression and loss of PTEN expression in non-small cell lung cancer confers poor prognosis
    • Tang JM, He QY, Guo RX and Chang XJ. Phosphorylated Akt overexpression and loss of PTEN expression in non-small cell lung cancer confers poor prognosis. Lung Cancer 2006; 51: 181-191.
    • (2006) Lung Cancer , vol.51 , pp. 181-191
    • Tang, J.M.1    He, Q.Y.2    Guo, R.X.3    Chang, X.J.4
  • 69
    • 0032577699 scopus 로고    scopus 로고
    • The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
    • Maehama T and Dixon JE. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 1998; 273: 13375-13378.
    • (1998) J Biol Chem , vol.273 , pp. 13375-13378
    • Maehama, T.1    Dixon, J.E.2
  • 70
    • 0035254648 scopus 로고    scopus 로고
    • Angiogenesis: Regulators and clinical applications
    • Liekens S, Clercq ED and Neyts J. Angiogenesis: regulators and clinical applications. Biochem Pharmacol 2001; 61: 253-270.
    • (2001) Biochem Pharmacol , vol.61 , pp. 253-270
    • Liekens, S.1    Clercq, E.D.2    Neyts, J.3
  • 71
    • 0029943568 scopus 로고    scopus 로고
    • Plasminogen activators and matrix metalloproteinases in angiogenesis
    • Mignatti P and Rifkin DB. Plasminogen activators and matrix metalloproteinases in angiogenesis. Enzyme Protein 1996; 49: 117-137.
    • (1996) Enzyme Protei , vol.49 , pp. 117-137
    • Mignatti, P.1    Rifkin, D.B.2
  • 72
    • 79952116210 scopus 로고    scopus 로고
    • Regulation of endothelial cell functions by basement membraneand arachidonic acid-derived products
    • Pozzi A and Zent R. Regulation of endothelial cell functions by basement membraneand arachidonic acid-derived products. Wiley Interdiscip Rev Syst Biol Med 2009; 1: 254-272.
    • (2009) Wiley Interdiscip Rev Syst Biol Med , vol.1 , pp. 254-272
    • Pozzi, A.1    Zent, R.2
  • 73
    • 34147171490 scopus 로고    scopus 로고
    • Endothelial cell migration during angiogenesis
    • Lamalice L, Boeuf FL and Huot J. Endothelial cell migration during angiogenesis. Circulation Res 2007; 100: 782-794.
    • (2007) Circulation Res , vol.100 , pp. 782-794
    • Lamalice, L.1    Boeuf, F.L.2    Huot, J.3
  • 74
    • 2942670657 scopus 로고    scopus 로고
    • Blockage of VEGF-induced angiogenesis by preventing VEGF secretion
    • Bjorndahl M, Cao R, Eriksson A and Cao Y, Blockage of VEGF-induced angiogenesis by preventing VEGF secretion. Circulation res 2004; 94: 1443-1450.
    • (2004) Circulation Res , vol.94 , pp. 1443-1450
    • Bjorndahl, M.1    Cao, R.2    Eriksson, A.3    Cao, Y.4
  • 75
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted antiogenic mitogen
    • Leung DW, Cachianes G, Kuang WJ, Goeddel DV and Ferrara N. Vascular endothelial growth factor is a secreted antiogenic mitogen. Science 1989; 246: 1306-1309.
    • (1989) Science , vol.246 , pp. 1306-1309
    • Leung, D.W.1    Cachianes, G.2    Kuang, W.J.3    Goeddel, D.V.4    Ferrara, N.5
  • 76
    • 33745738260 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer: From the biology to the clinic
    • Ranieri G, Patruno R, Ruggieri E, Montemurro S, Valerio P and Ribatti D. Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer: from the biology to the clinic. Curr Med Chem 2006; 13: 1845-1857.
    • (2006) Curr Med Chem , vol.13 , pp. 1845-1857
    • Ranieri, G.1    Patruno, R.2    Ruggieri, E.3    Montemurro, S.4    Valerio, P.5    Ribatti, D.6
  • 77
    • 0033205573 scopus 로고    scopus 로고
    • The role of the vascular phase in solid tumor growth: A historical review
    • Ribatti D, Vacca A and Dammacco F. The role of the vascular phase in solid tumor growth: A historical review. Neoplasia 1999; 1: 293-302.
    • (1999) Neoplasia , vol.1 , pp. 293-302
    • Ribatti, D.1    Vacca, A.2    Dammacco, F.3
  • 78
    • 38849187846 scopus 로고    scopus 로고
    • A theoretical study of the response of vascular tumours to different types of chemotherapy
    • Panovska J, Byrne HM, Maini PK. A theoretical study of the response of vascular tumours to different types of chemotherapy. Math Comp Mod 2008; 47: 560-579.
    • (2008) Math Comp Mod , vol.47 , pp. 560-579
    • Panovska, J.1    Byrne, H.M.2    Maini, P.K.3
  • 79
    • 0002964937 scopus 로고    scopus 로고
    • Avascular growth, angiogenesis and vascular growth in solid tumours: The mathematical modelling of the stages of tumour development
    • Chaplain MAJ. Avascular growth, angiogenesis and vascular growth in solid tumours: The mathematical modelling of the stages of tumour development. Mathematical and Computer Modelling 1996; 23: 47-87.
    • (1996) Mathematical and Computer Modelling , vol.23 , pp. 47-87
    • Chaplain, M.A.J.1
  • 80
    • 0030265393 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and its receptors
    • Klagsbrun M and D'Amore P. Vascular endothelial growth factor and its receptors. Cytokine Growth Factor Rev 1996; 7: 259-270.
    • (1996) Cytokine Growth Factor Rev , vol.7 , pp. 259-270
    • Klagsbrun, M.1    D'Amore, P.2
  • 81
    • 0031974158 scopus 로고    scopus 로고
    • Vascular endothelial growth factor/vascular permeability factor enhances vascular permeability via nitric oxide and prostacyclin
    • Murohara T, Horowitz JR, Silver M, Tsurumi Y, Chen D, Sullivan A, Isner JM. Vascular endothelial growth factor/vascular permeability factor enhances vascular permeability via nitric oxide and prostacyclin. Circulation 1998; 97: 99-107.
    • (1998) Circulation , vol.97 , pp. 99-107
    • Murohara, T.1    Horowitz, J.R.2    Silver, M.3    Tsurumi, Y.4    Chen, D.5    Sullivan, A.6    Isner, J.M.7
  • 82
    • 57349200481 scopus 로고    scopus 로고
    • VEGF and endothelial guidance in angiogenic sprouting
    • Gerhardt H. VEGF and endothelial guidance in angiogenic sprouting. Organogenesis 2008; 4: 241-246.
    • (2008) Organogenesis , vol.4 , pp. 241-246
    • Gerhardt, H.1
  • 83
    • 0029121235 scopus 로고
    • Angiogenesis: Mechanistic insights, neovascular diseases, and therapeutic prospects
    • Battegay EJ. Angiogenesis: mechanistic insights, neovascular diseases, and therapeutic prospects. J Mol Med 1995; 73: 333-346.
    • (1995) J Mol Med , vol.73 , pp. 333-346
    • Battegay, E.J.1
  • 86
    • 44449125132 scopus 로고    scopus 로고
    • Reactive Oxygen Species and Angiogenesis: NADPH Oxidase as Target for Cancer Therapy
    • Ushio-Fukai M and Nakamura Y. Reactive Oxygen Species and Angiogenesis: NADPH Oxidase as Target for Cancer Therapy. Cancer Lett 2008; 266: 37-52.
    • (2008) Cancer Lett , vol.266 , pp. 37-52
    • Ushio-Fukai, M.1    Nakamura, Y.2
  • 87
    • 0032545526 scopus 로고    scopus 로고
    • Stimulation of in vitro angiogenesis by hydrogen peroxide and the relation with ETS-1 in endothelial cells
    • Yasuda M, Ohzeki Y, Shimizu S, Naito S, Ohtsuru A, Yamamoto T and Kuroiwa Y. Stimulation of in vitro angiogenesis by hydrogen peroxide and the relation with ETS-1 in endothelial cells. Life Sci 1999; 64: 249-258.
    • (1999) Life Sci , vol.64 , pp. 249-258
    • Yasuda, M.1    Ohzeki, Y.2    Shimizu, S.3    Naito, S.4    Ohtsuru, A.5    Yamamoto, T.6    Kuroiwa, Y.7
  • 88
    • 2942670657 scopus 로고    scopus 로고
    • Blockage of VEGF-Induced Angiogenesis by Preventing VEGF Secretion
    • Bjorndahl M, Cao R, Eriksson A and Cao Y. Blockage of VEGF-Induced Angiogenesis by Preventing VEGF Secretion. Circulation Res 2004; 94: 1443-1450.
    • (2004) Circulation Res , vol.94 , pp. 1443-1450
    • Bjorndahl, M.1    Cao, R.2    Eriksson, A.3    Cao, Y.4
  • 89
    • 0031974158 scopus 로고    scopus 로고
    • Vascular Endothelial Growth Factor/Vascular Permeability Factor Enhances Vascular Permeability Via Nitric Oxide and Prostacyclin
    • Murohara T, Horowitz JR, Silver M, Tsurumi Y, Chen D, Sullivan A, Isner JM. Vascular Endothelial Growth Factor/Vascular Permeability Factor Enhances Vascular Permeability Via Nitric Oxide and Prostacyclin. Circulation 1998; 97: 99-107.
    • (1998) Circulation , vol.97 , pp. 99-107
    • Murohara, T.1    Horowitz, J.R.2    Silver, M.3    Tsurumi, Y.4    Chen, D.5    Sullivan, A.6    Isner, J.M.7
  • 90
    • 33745738260 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer: From the biology to the clinic
    • Ranieri G, Patruno R, Ruggieri E, Montemurro S, Valerio P, Ribatti D. Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer: from the biology to the clinic. Curr Med Chem 2006; 13: 1845-1857.
    • (2006) Curr Med Chem , vol.13 , pp. 1845-1857
    • Ranieri, G.1    Patruno, R.2    Ruggieri, E.3    Montemurro, S.4    Valerio, P.5    Ribatti, D.6
  • 91
    • 3042771836 scopus 로고    scopus 로고
    • Antisense-mediated VEGF suppression in bladder and breast cancer cells
    • Forster Y, Meye A, Krause S and Schwenzer B. Antisense-mediated VEGF suppression in bladder and breast cancer cells. Cancer Lett 2004; 20: 95-103.
    • (2004) Cancer Lett , vol.20 , pp. 95-103
    • Forster, Y.1    Meye, A.2    Krause, S.3    Schwenzer, B.4
  • 93
    • 17444374974 scopus 로고    scopus 로고
    • Angiogenesis: A curse or cure?
    • Gupta K and Zhang J. Angiogenesis: a curse or cure? Postgrad Med J 2005; 81: 236-242.
    • (2005) Postgrad Med J , vol.81 , pp. 236-242
    • Gupta, K.1    Zhang, J.2
  • 94
    • 34247849335 scopus 로고    scopus 로고
    • Target Practice: Lessons from Phase III Trials with Bevacizumab and Vatalanib in the Treatment of Advanced Colorectal Cancer
    • Los M, Roodhart JLM and Voest EE. Target Practice: Lessons from Phase III Trials with Bevacizumab and Vatalanib in the Treatment of Advanced Colorectal Cancer. The Oncologist 2007; 12: 443-450.
    • (2007) The Oncologist , vol.12 , pp. 443-450
    • Los, M.1    Roodhart, J.L.M.2    Voest, E.E.3
  • 96
    • 4444339437 scopus 로고    scopus 로고
    • Current approaches and perspectives in the medical treatment of diabetic retinopathy
    • Porta M and Allione A. Current approaches and perspectives in the medical treatment of diabetic retinopathy. Pharmacol Ther 2004; 103: 167-77.
    • (2004) Pharmacol Ther , vol.103 , pp. 167-177
    • Porta, M.1    Allione, A.2
  • 97
    • 0036157485 scopus 로고    scopus 로고
    • Many actions of cyclooxygenase-2 in cellular dynamics and in cancer
    • Cao Y and Prescott SM. Many actions of cyclooxygenase-2 in cellular dynamics and in cancer. J Cell Physiol 2002; 190: 279-286.
    • (2002) J Cell Physiol , vol.190 , pp. 279-286
    • Cao, Y.1    Prescott, S.M.2
  • 98
    • 33846531356 scopus 로고    scopus 로고
    • The tumour microenvironment as a target for chemoprevention
    • Albini A and Sporn MB. The tumour microenvironment as a target for chemoprevention. Nat Rev Cancer 2007; 7: 139-47.
    • (2007) Nat Rev Cancer , vol.7 , pp. 139-147
    • Albini, A.1    Sporn, M.B.2
  • 99
    • 34047132303 scopus 로고    scopus 로고
    • Apigenin inhibits tumor angiogenesis through decreasing HIF-1α and VEGF expression
    • Fang J, Zhou Q, Liu LZ, Xia C, Hu X, Shi X and Jiang BH. Apigenin inhibits tumor angiogenesis through decreasing HIF-1α and VEGF expression. Carcinogenesis 2006; 28: 858-864.
    • (2006) Carcinogenesis , vol.28 , pp. 858-864
    • Fang, J.1    Zhou, Q.2    Liu, L.Z.3    Xia, C.4    Hu, X.5    Shi, X.6    Jiang, B.H.7
  • 100
    • 39149110961 scopus 로고    scopus 로고
    • Tumor angiogenesisa potential target in cancer chemoprevention
    • Bhat TA and Singh RP. Tumor angiogenesisa potential target in cancer chemoprevention. Food Chem Toxicol 2008; 46: 1334-1345.
    • (2008) Food Chem Toxicol , vol.46 , pp. 1334-1345
    • Bhat, T.A.1    Singh, R.P.2
  • 101
    • 77950915623 scopus 로고    scopus 로고
    • Novel angiogenesis inhibitory activity in cinnamon extract blocks VEGFR2 kinase and downstream signaling
    • Lu J, Zhang K, Nam S, Anderson RA, Jove R and Wen W. Novel angiogenesis inhibitory activity in cinnamon extract blocks VEGFR2 kinase and downstream signaling. Carcinogenesis 2010; 31: 481-488.
    • (2010) Carcinogenesis , vol.31 , pp. 481-488
    • Lu, J.1    Zhang, K.2    Nam, S.3    Anderson, R.A.4    Jove, R.5    Wen, W.6
  • 103
    • 0032889698 scopus 로고    scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor and the significance of microvascular hyperpermeability in angiogenesis
    • Dvorak HF, Nagy JA, Feng D, Brown LF, Dvorak AM. Vascular permeability factor/vascular endothelial growth factor and the significance of microvascular hyperpermeability in angiogenesis. Curr Top Microbiol Immunol 1999; 237: 97-132.
    • (1999) Curr Top Microbiol Immunol , vol.237 , pp. 97-132
    • Dvorak, H.F.1    Nagy, J.A.2    Feng, D.3    Brown, L.F.4    Dvorak, A.M.5
  • 104
    • 33749028188 scopus 로고    scopus 로고
    • Vascular endothelial growth factor signaling pathways: Therapeutic perspective
    • Kowanetz M and Ferrara N. Vascular endothelial growth factor signaling pathways: therapeutic perspective. Clin Cancer Res 2006; 12; 5018.
    • (2006) Clin Cancer Res , vol.12 , pp. 5018
    • Kowanetz, M.1    Ferrara, N.2
  • 106
    • 0031779927 scopus 로고    scopus 로고
    • Vascular endothelial growth factor mediates angiogenic activity during the proliferative phase of wound healing
    • Nissen NN, Polverini PJ, Koch AE, Volin MV, Gamelli RL, DiPietro LA. Vascular endothelial growth factor mediates angiogenic activity during the proliferative phase of wound healing. Am J Pathol 1998; 152: 1445-1452.
    • (1998) Am J Pathol , vol.152 , pp. 1445-1452
    • Nissen, N.N.1    Polverini, P.J.2    Koch, A.E.3    Volin, M.V.4    Gamelli, R.L.5    Dipietro, L.A.6
  • 107
    • 0026756163 scopus 로고
    • Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocytes during wound healing
    • Brown LF, Yeo KT, Berse B, Yeo TK, Senger DR, Dvorak HF, van de Water L. Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocytes during wound healing. J Exp Med 1992; 176: 1375-1379.
    • (1992) J Exp Med , vol.176 , pp. 1375-1379
    • Brown, L.F.1    Yeo, K.T.2    Berse, B.3    Yeo, T.K.4    Senger, D.R.5    Dvorak, H.F.6    van de Water, L.7
  • 109
    • 0041842763 scopus 로고    scopus 로고
    • Regulation of vascular permeability by vascular endothelial growth factors
    • Bates DO and Harper SJ. Regulation of vascular permeability by vascular endothelial growth factors. Vascul Pharmacol 2002; 39: 225-37.
    • (2002) Vascul Pharmacol , vol.39 , pp. 225-237
    • Bates, D.O.1    Harper, S.J.2
  • 113
    • 0029153544 scopus 로고
    • Hypoxia-induced expression of vascular endothelial growth factor by retinal glial cells promotes in vitro angiogenesis
    • Hata Y, Nakagawa K, Ishibashi T, Inomata H, Ueno H and Sueishi K. Hypoxia-induced expression of vascular endothelial growth factor by retinal glial cells promotes in vitro angiogenesis. Virchows Arch 1995; 426: 479-486.
    • (1995) Virchows Arch , vol.426 , pp. 479-486
    • Hata, Y.1    Nakagawa, K.2    Ishibashi, T.3    Inomata, H.4    Ueno, H.5    Sueishi, K.6
  • 115
    • 0035086875 scopus 로고    scopus 로고
    • Regulation of retinal capillary cells by basic fibroblast growth factor, vascular endothelial growth factor, and hypoxia
    • Yan Q, Li Y, Hendrickson A and Sage EH. Regulation of retinal capillary cells by basic fibroblast growth factor, vascular endothelial growth factor, and hypoxia. In Vitro Cell Dev Biol Anim 2001; 37: 45-49.
    • (2001) In Vitro Cell Dev Biol Anim , vol.37 , pp. 45-49
    • Yan, Q.1    Li, Y.2    Hendrickson, A.3    Sage, E.H.4
  • 116
    • 0031126380 scopus 로고    scopus 로고
    • Intravitreal sustained release of VEGF causes retinal neovascularization in rabbits and breakdown of the blood-retinal barrier in rabbits and primates
    • Ozaki H, Hayashi H, Vinores SA, Moromizato Y, Campochiaro PA, Oshima K. Intravitreal sustained release of VEGF causes retinal neovascularization in rabbits and breakdown of the blood-retinal barrier in rabbits and primates. Exp Eye Res 1997; 64: 505-517.
    • (1997) Exp Eye Res , vol.64 , pp. 505-517
    • Ozaki, H.1    Hayashi, H.2    Vinores, S.A.3    Moromizato, Y.4    Campochiaro, P.A.5    Oshima, K.6
  • 117
    • 0346494560 scopus 로고    scopus 로고
    • Protein kinase C inhibition and diabetic retinopathy: A shot in the dark at translational research
    • Donnelly R, Idris I and Forrester JV. Protein kinase C inhibition and diabetic retinopathy: a shot in the dark at translational research. Br J Ophthalmol 2004; 88: 145-151.
    • (2004) Br J Ophthalmol , vol.88 , pp. 145-151
    • Donnelly, R.1    Idris, I.2    Forrester, J.V.3
  • 118
    • 0027454103 scopus 로고
    • Correlation of diacylglycerol and protein kinase C activity in rat retina to retinal circulation
    • Shiba T, Inoguchi T, Sportsman JR, Heath WF, Bursell S, King GL. Correlation of diacylglycerol and protein kinase C activity in rat retina to retinal circulation. Am J Physiol 1993; 265: 783-793.
    • (1993) Am J Physiol , vol.265 , pp. 783-793
    • Shiba, T.1    Inoguchi, T.2    Sportsman, J.R.3    Heath, W.F.4    Bursell, S.5    King, G.L.6
  • 119
    • 18044374094 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression and secretion by retinal pigment epithelial cells in high glucose and hypoxia is protein kinase Cdependent
    • Young TA, Wang H, Munk S, Hammoudi DS, Young DS, Mandelcorn MS, Whiteside CI. Vascular endothelial growth factor expression and secretion by retinal pigment epithelial cells in high glucose and hypoxia is protein kinase Cdependent. Exp Eye Res 2005; 80: 651-662.
    • (2005) Exp Eye Res , vol.80 , pp. 651-662
    • Young, T.A.1    Wang, H.2    Munk, S.3    Hammoudi, D.S.4    Young, D.S.5    Mandelcorn, M.S.6    Whiteside, C.I.7
  • 120
    • 0035711473 scopus 로고    scopus 로고
    • Diabetes-induced elevations in retinal oxidative estress, protein kinase C and nitric oxide are interrelated
    • Kowluru RA. Diabetes-induced elevations in retinal oxidative estress, protein kinase C and nitric oxide are interrelated. Acta Diabetol 2001; 38: 179-185.
    • (2001) Acta Diabetol , vol.38 , pp. 179-185
    • Kowluru, R.A.1
  • 121
  • 122
    • 0025610836 scopus 로고
    • Adenylate cyclase and protein kinase C mediate opposite actions on endothelial junctions
    • Oliver JA. Adenylate cyclase and protein kinase C mediate opposite actions on endothelial junctions. J Cell Physiol 1990; 145: 536-542.
    • (1990) J Cell Physiol , vol.145 , pp. 536-542
    • Oliver, J.A.1
  • 124
    • 0026035977 scopus 로고
    • Diacylglycerol accumulation and microvascular abnormalities induced by elevated glucose levels
    • Wolf BA, Williamson JR, Easom RA, Chang K, Sherman WR and Turk J. Diacylglycerol accumulation and microvascular abnormalities induced by elevated glucose levels. J Clin Invest 1991; 87: 31-38.
    • (1991) J Clin Invest , vol.87 , pp. 31-38
    • Wolf, B.A.1    Williamson, J.R.2    Easom, R.A.3    Chang, K.4    Sherman, W.R.5    Turk, J.6
  • 125
    • 0021100170 scopus 로고
    • A cytoskeletal substrate of protein kinase C
    • Werth DK, Niedel JE and Vinculin IP. A cytoskeletal substrate of protein kinase C. J Biol Chem 1983; 258: 11423-11426.
    • (1983) J Biol Chem , vol.258 , pp. 11423-11426
    • Werth, D.K.1    Niedel, J.E.2    Vinculin, I.P.3
  • 126
    • 0026781107 scopus 로고
    • Protein kinase C phosphorylates caldesmon and vimentin and enhances albumin permeability across cultured bovine pulmonary artery endothelial cell monolayers
    • Stasek JE, Patterson CE and Garcia JGN. Protein kinase C phosphorylates caldesmon and vimentin and enhances albumin permeability across cultured bovine pulmonary artery endothelial cell monolayers. J Cell Physiol 1992; 153: 62-75.
    • (1992) J Cell Physiol , vol.153 , pp. 62-75
    • Stasek, J.E.1    Patterson, C.E.2    Garcia, J.G.N.3
  • 127
    • 0000324360 scopus 로고
    • Elevated glucose level regulates epidermal growth factor receptor (EGF-R) in aortic smooth muscle cells overexpressing protein kinase C
    • Xia P, Feener EP and King GL. Elevated glucose level regulates epidermal growth factor receptor (EGF-R) in aortic smooth muscle cells overexpressing protein kinase C. Diabetes 1994.
    • (1994) Diabetes
    • Xia, P.1    Feener, E.P.2    King, G.L.3
  • 128
    • 0028911330 scopus 로고
    • Diabetic microvascular complications and growth factors
    • Pfeiffer A and Schatz H. Diabetic microvascular complications and growth factors. Exp Clin Endocrinol Diabetes 1995; 103: 7-14.
    • (1995) Exp Clin Endocrinol Diabetes , vol.103 , pp. 7-14
    • Pfeiffer, A.1    Schatz, H.2
  • 129
    • 0031685823 scopus 로고    scopus 로고
    • Hepatocyte growth factor in vitreous fluid of patients with proliferative diabetic retinopathy and other retinal disorders
    • Katsura Y, Okano T, Noritake M, Kosano H, Nishigori H, Kado S, Matsuoka T. Hepatocyte growth factor in vitreous fluid of patients with proliferative diabetic retinopathy and other retinal disorders. Diabetes Care 1998; 21: 1759-1763.
    • (1998) Diabetes Care , vol.21 , pp. 1759-1763
    • Katsura, Y.1    Okano, T.2    Noritake, M.3    Kosano, H.4    Nishigori, H.5    Kado, S.6    Matsuoka, T.7
  • 130
    • 34250702110 scopus 로고    scopus 로고
    • The role of protein kinase C activation and the vascular complications of diabetes
    • Evcimen ND and King GL. The role of protein kinase C activation and the vascular complications of diabetes. Pharmacol Res 2007; 55: 498-510.
    • (2007) Pharmacol Res , vol.55 , pp. 498-510
    • Evcimen, N.D.1    King, G.L.2
  • 131
    • 46149092748 scopus 로고    scopus 로고
    • Role of mTOR in anticancer drug resistance
    • Jiang BH and Liu LZ. Role of mTOR in anticancer drug resistance. Drug Resist Updat 2008; 11: 63-76.
    • (2008) Drug Resist Updat , vol.11 , pp. 63-76
    • Jiang, B.H.1    Liu, L.Z.2
  • 132
    • 0033551070 scopus 로고    scopus 로고
    • New insights into tumor suppression: PTEN Suppresses tumor formation by restraining academy the phosphoinositide 3-kinase/AKT pathway
    • Cantley LC and Neel BG. New insights into tumor suppression: PTEN Suppresses tumor formation by restraining academy the phosphoinositide 3-kinase/AKT pathway. Proc Nat Sci USA 1999; 96: 4240-4245.
    • (1999) Proc Nat Sci USA , vol.96 , pp. 4240-4245
    • Cantley, L.C.1    Neel, B.G.2
  • 133
    • 0032486198 scopus 로고    scopus 로고
    • Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
    • Tamura M, Gu J, Matsumoto K, Aota SI, Parsons R and Yamada KM. Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science 1998; 280: 1614-1617.
    • (1998) Science , vol.280 , pp. 1614-1617
    • Tamura, M.1    Gu, J.2    Matsumoto, K.3    Aota, S.I.4    Parsons, R.5    Yamada, K.M.6
  • 134
    • 81555220913 scopus 로고    scopus 로고
    • The Role of PTEN in Tumor Angiogenesis
    • Rodriguez S, Huynh-Do U. The Role of PTEN in Tumor Angiogenesis. J Oncol 2012; 2012: 141236.
    • (2012) J Oncol 2012 , pp. 141236
    • Rodriguez, S.1    Huynh-Do, U.2
  • 135
    • 34249825478 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and its relationship to inflammatory mediators
    • Angelo LS and Kurzrock R. Vascular endothelial growth factor and its relationship to inflammatory mediators. Clin Cancer Res 2007; 15: 2825.
    • (2825) Clin Cancer Res , vol.2007 , pp. 15
    • Angelo, L.S.1    Kurzrock, R.2
  • 136
    • 0027425753 scopus 로고
    • Mitotic activity, apoptosis and TRPM-2 mRNA expression in DMBA induced rat mammary carcinoma treated with anti-estrogen toremifene
    • Huovinen R, Warri A and Collan Y. Mitotic activity, apoptosis and TRPM-2 mRNA expression in DMBA induced rat mammary carcinoma treated with anti-estrogen toremifene. Int J Cancer 1993; 55: 685-691.
    • (1993) Int J Cancer , vol.55 , pp. 685-691
    • Huovinen, R.1    Warri, A.2    Collan, Y.3
  • 138
    • 0033988498 scopus 로고    scopus 로고
    • Eukaryotic initiation factor-4E in superficial and muscle invasive bladder cancer and its correlation with vascular endothelial growth factor expression and tumour progression
    • Crew JP, Fuggle S, Bicknell R, Cranston DW, de Benedetti A and Harris AL. Eukaryotic initiation factor-4E in superficial and muscle invasive bladder cancer and its correlation with vascular endothelial growth factor expression and tumour progression. Br J Cancer 2000; 82: 161-166.
    • (2000) Br J Cancer , vol.82 , pp. 161-166
    • Crew, J.P.1    Fuggle, S.2    Bicknell, R.3    Cranston, D.W.4    de Benedetti, A.5    Harris, A.L.6
  • 140
    • 0024436264 scopus 로고
    • Studies on the ability of smoke from different types of cigarettes to induce DNA single-strand breaks in cultured human cells
    • Fielding S, Short C, Davies K, Wald N, Bridges BA and Waters R. Studies on the ability of smoke from different types of cigarettes to induce DNA single-strand breaks in cultured human cells. Mutat Res 1989; 214: 147-151.
    • (1989) Mutat Res , vol.214 , pp. 147-151
    • Fielding, S.1    Short, C.2    Davies, K.3    Wald, N.4    Bridges, B.A.5    Waters, R.6
  • 141
    • 0028075560 scopus 로고
    • Quantification of angiogenesis as an independent predictor of prognosis in invasive bladder carcinomas
    • Dickinson AJ, Fox SB, Persad RA, Hollyer J, Sibley GN, Harris AL. Quantification of angiogenesis as an independent predictor of prognosis in invasive bladder carcinomas. Br J Urol 1994 Dec; 74: 762-6.
    • (1994) Br J Urol , vol.74 , pp. 762-766
    • Dickinson, A.J.1    Fox, S.B.2    Persad, R.A.3    Hollyer, J.4    Sibley, G.N.5    Harris, A.L.6
  • 143
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • Ferrara N and Davis-Smyth TD. The biology of vascular endothelial growth factor. Endocr Rev 1997; 10: 4-25.
    • (1997) Endocr Rev , vol.10 , pp. 4-25
    • Ferrara, N.1    Davis-Smyth, T.D.2


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