Alkane-modified low-molecular-weight polyethylenimine with enhanced gene silencing for siRNA delivery

International Journal of Pharmaceutics

Volumn 450, Issue 1-2, 2013, Pages 44-52

  Guo, Gaoyang ^a,d   Zhou, Li ^a,d   Chen, Zhifei ^a   Chi, Weilin ^a   Yang, Xiuqun ^b   Wang, Wei ^a,d   Zhang, Biliang ^a,c  

^a GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

^b Guangzhou Science Park   (China)

^c GUANGZHOU MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Hydrophobic modification; Nanoparticles; Polyethylenimine; siRNA delivery

Indexed keywords

ACRYLAMIDE DERIVATIVE; ALKANE DERIVATIVE; LIPOFECTAMINE; LUCIFERASE; NANOPARTICLE; OCTYLACRYLAMIDE; POLYCATION; POLYETHYLENEIMINE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG EFFICACY; DRUG UPTAKE; FLOW CYTOMETRY; GENE DELIVERY SYSTEM; GENE SILENCING; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VITRO STUDY; LIGHT SCATTERING; MOLECULAR WEIGHT; NUCLEAR MAGNETIC RESONANCE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; ZETA POTENTIAL;

ACRYLAMIDES; CELL LINE, TUMOR; CELL MEMBRANE PERMEABILITY; GENE SILENCING; HEMOLYSIS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MOLECULAR WEIGHT; POLYETHYLENEIMINE; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 84877600693     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.04.024     Document Type: Article

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