Inhibition of histone deacetylation induces constitutive derepression of the beta interferon promoter and confers antiviral activity

Journal of Virology

Volumn 75, Issue 7, 2001, Pages 3444-3452

  Shestakova, E ^a   Bandu, M T ^a   Doly, J ^a   Bonnefoy, E ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; HISTONE DEACETYLASE;

ANTIVIRAL ACTIVITY; ARTICLE; CELL VIABILITY; DEACETYLATION; ENHANCER REGION; GENETIC REGULATION; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION REGULATION; VESICULAR STOMATITIS VIRUS; VIROGENESIS; VIRUS ACTIVATION; VIRUS INDUCTION;

ACETYLATION; ANIMALS; ANTIVIRAL AGENTS; CELL LINE; DNA METHYLATION; HISTONE DEACETYLASES; HISTONES; HYDROXAMIC ACIDS; INTERFERON-BETA; MICE; PROMOTER REGIONS (GENETICS);

EID: 0035107064     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.7.3444-3452.2001     Document Type: Article

References (64)

1. Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation
2. Role for N-Cor and histone deacetylase in Sin3-mediated transcriptional repression
3. Methylation meets acetylation
4. Specific binding of high-mobility-group I (HMGI) protein and histone H1 to the upstream AT-rich region of the murine beta interferon promoter: HMGI protein acts as a potential antirepressor of the promoter
5. Transcriptional silencing in yeast is associated with reduced nucleosome acetylation
6. Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern
7. Retinoblastome protein recruits histone deacetylase to repress transcription
8. Repression of the murine interferon alpha 11 gene: Identification of negative acting sequences
9. Control of histone modifications
10. Type I interferons: Expression and signalization
11. The human β-interferon gene enhancer is under negative control
12. Overlapping positive and negative regulatory domains of the human β-interferon gene
13. Fusion proteins of the retinoic acid receptor-α recruit histone deacetylase in promyelocytic leukaemia
14. Three proteins define a class of human histone deacetylases related to yeast Hdap1
15. Histone acetylation in chromatin structure and transcription
16. Nucleosomes and transcription: Recent lessons from genetics
17. A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression
18. Activation domain-specific and general transcription stimulation by native histone acetyltransferase complexes
19. Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
20. Identification and characterization of a novel repressor of β-interferon gene expression
21. Prolonged glucocorticoid exposure dephosphorylates histone HI and inactivates the MMTV promoter
22. Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation
23. Role of the histone deacetylase complex in acute promyelocytic leukaemia
24. Rb interacts with histone deacetylase to repress transcription
25. Retinoblastoma protein represses transcription by recruiting a histone deacetylase
26. Positive and negative control of human interferon-β gene expression
27. Structure and function of the interferon-beta enhanceosome
28. The histone acetylase PCAF is a phorbol-ester-inducible coactivator of the IRF family that confers enhanced interferon responsiveness
29. Recruitment of CBP/p300 by the IFNβ enhanceosome is required for synergistic activation of transcription
30. A histone deacetylase inhibitor potentiates retinoid receptor action in embryonal carcinoma cells
31. HDAC4 deacetylase associates with and represses the MEF2 transcription factor
32. Kinetic evidence for an activation step following binding of human interferon α2 to the membrane receptors of Daudi cells
33. Acetylation of HMGI(Y) by CBP turns off IFNβ expression by disrupting the enhanceosome
34. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
35. Histone deacetylase mRNA temporarly and spatially regulated in its expression in sea urchin embryos
36. Histone acetylation facilitates RNA polymerase II transcription of the Drosophila hsp26 gene in chromatin
37. Interferon-β promoters contain a DNA element that acts as a position-independent silencer on the NF-κB site
38. Constitutive silencing of IFN-β promoter is mediated by NRF (NF-κB-repressing factor), a nuclear inhibitor of NF-κB
39. The transcriptional coactivators p300 and CBP are histone acetyltransferases
40. A developmental switch in H4 acetylation upstream of Xist plays a role in X chromosome inactivation
41. Virus infection leads to localized hyperacetylation of histones H3 and H4 at the IFN-β promoter
42. Constitutive expression of an ISGF2/IRF1 transgene leads to interferon-independent activation of interferon-inducible genes and resistance to virus infection
43. CpG methylation, chromatin structure and gene silencing - A three-way connection
44. PRD1-BF1/Blimp-1 repression is mediated by corepressors of the Groucho family of proteins
45. Maternal histone deacetylase is accumulated in the nuclei of Xenopus oocytes as protein complexes with potential enzyme activity
46. Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects
47. A role for the architectural transcription factors HMGI(Y) in cytokine gene transcription in T cells
48. Transcriptional regulation of mammalian genes in vivo. A tale of two templates
49. Fundamentally different logic of gene regulation in eukaryotes and prokaryotes
50. Mouse embryos do not wait for the MBT:chromatin and RNA polymerase remodeling in genome activation at the onset of development
51. Histone acetylation: Influence on transcription, nucleosome mobility and positioning, and linker histone-dependent transcriptional repression
52. The nuclear factor-κB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter
53. The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation
54. Chromatin and chromosomal controls in development
55. Therapeutic targeting of transcriotion in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase
56. Virus infection induces the assembly of coordinately activated transcription factors on the IFN-β enhancer in vivo
57. Postinduction repression of the β-interferon gene is mediated through two positive regulatory domains
58. Sinful repression
59. Alteration of nucleosome structure as a mechanism of transcriptional regulation
60. Chromatin remodeling and the control of gene expression
61. Direct triggering of the type I interferon system by virus infection: Activation of a transcription factor complex containing IRF-3 and CBP/p300
62. Identification of two distinct regulatory regions adjacent to the human β-interferon gene
63. Detection of factors that interact with the human β-interferon regulatory region in vivo by DNAse I footprinting