Daily methylphenidate and atomoxetine treatment impacts on clock gene protein expression in the mouse brain

Brain Research

Volumn 1513, Issue , 2013, Pages 61-71

  Baird, Alison L ^a,f   Coogan, Andrew N ^b   Kaufling, Jennifer ^c,d   Barrot, Michel ^c,d   Thome, Johannes ^a,e  

^a SWANSEA UNIVERSITY   (United Kingdom)

^b NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^c CNRS   (France)

^d UNIVERSITÉ DE STRASBOURG   (France)

^e UNIVERSITY OF ROSTOCK   (Germany)

^f KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

ADHD; Atomoxetine; Circadian; Methylphenidate; Suprachiasmatic

Indexed keywords

ATOMOXETINE; METHYLPHENIDATE; TRANSCRIPTION FACTOR CLOCK; CENTRAL STIMULANT AGENT; PROPYLAMINE; PROTEIN C FOS;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATTENTION DEFICIT DISORDER; BASOLATERAL AMYGDALA; BRAIN; BRAIN CORTEX; CENTRAL NUCLEUS (AMYGDALA); CINGULATE GYRUS; CIRCADIAN RHYTHM; CONTROLLED STUDY; CORPUS STRIATUM; DENTATE GYRUS; FOREBRAIN; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA3 REGION; HYPOTHALAMUS; MALE; MOUSE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUPRACHIASMATIC NUCLEUS; VENTRAL TEGMENTUM; ANALYSIS OF VARIANCE; ANATOMY AND HISTOLOGY; ANIMAL; C57BL MOUSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM; NEUROIMAGING;

ANALYSIS OF VARIANCE; ANIMALS; BRAIN; CENTRAL NERVOUS SYSTEM STIMULANTS; CIRCADIAN RHYTHM; CLOCK PROTEINS; GENE EXPRESSION REGULATION; MALE; METHYLPHENIDATE; MICE; MICE, INBRED C57BL; NEUROIMAGING; PROPYLAMINES; PROTO-ONCOGENE PROTEINS C-FOS;

EID: 84877581567     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2013.03.038     Document Type: Article

References (52)

1. M.F. Algahim, P.B. Yang, V.T. Wilcox, K.D. Burau, A.C. Swann, and N. Dafny Prolonged methylphenidate treatment alters the behavioral diurnal activity pattern of adult male Sprague-Dawley rats Pharmacol. Biochem. Behav. 92 2009 93 99
2. M.F. Algahim, P.B. Yang, K.D. Burau, A.C. Swann, and N. Dafny Repetitive ritalin treatment modulates the diurnal activity pattern of young SD male rats Cent. Nerv. Syst. Agents Med. Chem. 10 2010 247 257
3. S. Amir, E.W. Lamont, B. Robinson, and J. Stewart A circadian rhythm in the expression of PERIOD2 protein reveals a novel SCN-controlled oscillator in the oval nucleus of the bed nucleus of the stria terminalis J. Neurosci. 24 2004 781 790
4. M.C. Antle, H.C. van Diepen, T. Deboer, P. Pedram, R. Rodrigues Pereira, and J.H. Meijer Methylphenidate modifies the motion of the circadian clock Neuropsychopharmacology 37 2012 2446 2465
5. J. Biederman, and S.V. Faraone Attention-deficit hyperactivity disorder Lancet 366 2005 237 248
6. A.M. Boonstra, J.J. Kooij, J. Oosterlaan, J.A. Sergeant, J.K. Buitelaar, and E.J. Van Someren Hyperactive night and day? Actigraphy studies in adult ADHD: a baseline comparison and the effect of methylphenidate Sleep 30 2007 433 442
7. A.L. Baird, A.N. Coogan, A. Siddiqui, R.M. Donev, and J. Thome Adult attention-deficit hyperactivity disorder is associated with alterations in circadian rhythms at the behavioural, endocrine and molecular levels Mol. Psychiatry 2011 2011 E-pub Nov
8. Z. Bendova, and A. Sumova Photoperiodic regulation of PER1 and PER2 protein expression in rat peripheral tissues Physiol. Res. 55 2006 623 632
9. A.L. Beynon, J. Thome, and A.N. Coogan Age and time of day influences on the expression of transforming growth factor-beta and phosphorylated SMAD3 in the mouse suprachiasmatic and paraventricular nuclei Neuroimmunomodulation 16 2009 392 399
10. FP Bymaster, JS Katner, DL Nelson, SK Hemrick-Luecke, PG Threlkeld, JH Heiligenstein, and SM Morin Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder Neuropsychopharmacology 27 2002 699 711
11. Y.M. Cui, C.H. Teng, A.X. Pan, E. Yuen, K.P. Yeo, Y. Zhou, X. Zhao, A.J. Long, M.E. Bangs, and S.D. Wise Atomoxetine pharmacokinetics in healthy Chinese subjects and effect of the CYP2D6*10 allele Br. J. Clin. Pharmacol. 6 2007 445 449
12. D. Coghill, and S. Seth Osmotic, controlled-release methylphenidate for the treatment of ADHD Expert Opin. Pharmacother 7 2006 2119 2138
13. A.N. Coogan, A. Dobrean, R.M. Donev, L. Mattescu, U. Muller, J. Thome, and B.I. Voinescu Adult Attention Deficit Hyperactivity Disorder - Translating Research into Clinical Practice Attent. Def. Hyperact. Disord 2012 2012 E-pub Feb
14. A.N. Coogan, M.M. Papachatzaki, C. Clemens, A. Baird, R.M. Donev, J. Joosten, V Zacchariou, and J. Thome Haloperidol alters circadian clock gene product expression in the mouse brain World J. Biol. Psychiatry 12 2011 638 644
15. F.R. Cagampang, H. Okamura, and S. Inouye Circadian rhythms of norepinephrine in the rat suprachiasmatic nucleus Neurosci. Lett 173 1994 185 188
16. E. Challet, S. Dumont, M.K. Mehdi, C. Allemann, T. Bousser, S. Gourmelen, D. Sage-Ciocca, D. Hicks, P. Pévet, and B. Claustrat Aging-like circadian disturbances in folate-deficient mice Neurobiol. Aging E pub Dec 2012 2012
17. J.P. Debruyne, E. Noton, C.M. Lambert, E.S. Maywood, D.R. Weaver, and S.M. Reppert A clock shock: mouse CLOCK is not required for circadian oscillator function 50 2006 465 477 Neuron 50 2006 465 477
18. C. Dibner, U. Schibler, and U. Albrecht The mammalian circadian timing system: organization and coordination of central and peripheral clocks Annu. Rev. Physiol 72 2010 517 549
19. C.A. Feillet, J. Mendoza, U. Albrecht, P. Pevet, and E. Challet Forebrain oscillators ticking with different clock hands Mol. Cell Neurosci. 37 2008 209 221
20. O. Gaytan, P. Yang, A. Swann, and N. Dafny Diurnal differences in sensitization to methylphenidate Brain Res. 864 2000 24 39
21. J.R. Gerstner, and J.C. Yin Circadian rhythms and memory formation Nat. Rev. Neurosci 11 2010 577 588
22. C. Guilding, and H.D. Piggins Challenging the omnipotence of the suprachiasmatic timekeeper: are circadian oscillators present throughout the mammalian brain? Eur. J. Neurosci. 25 2007 3195 3216
23. S. Honma, and K. Honma Locomotor rhythms induced by methylphenidate in suprachiasmatic nuclei-lesioned rats Neurosci. Lett 137 1992 24 28
24. T.M. Keck, K.L. Suchland, C.C. Jimenez, and D.K. Grandy Dopamine D4 receptor deficiency in mice alters behavioral responses to anxiogenic stimuli and the psychostimulant methylphenidate Pharmacol. Biochem. Behav. 103 2012 831 841
25. C. Kissling, W. Retz, S. Wiemann, A.N. Coogan, R.M. Clement, R. Hunnerkopf, and J. Thome A polymorphism at the 3'-untranslated region of the CLOCK gene is associated with adult attention-deficit hyperactivity disorder Am. J. Med. Genet. B Neuropsychiatr. Genet. 147 2008 333 338
26. K. Koda, Y. Ago, Y. Cong, Y. Kita, K. Takuma, and T. Matsuda Effects of acute and chronic administration of atomoxetine and methylphenidate on extracellular levels of noradrenaline, dopamine and serotonin in the prefrontal cortex and striatum of mice J. Neurochem. 114 2010 259 270
27. E.W. Lamont, B. Robinson, J. Stewart, and S. Amir The central and basolateral nuclei of the amygdala exhibit opposite diurnal rhythms of expression of the clock protein Period2 Proc. Natl. Acad. Sci. USA 102 2005 4180 4184
28. J. LeSauter, L. Yan, B. Vishnubhotla, J.E. Quintero, S.J. Kuhlman, D.G. McMahon, and R. Silver A short half-life GFP mouse model for analysis of suprachiasmatic nucleus organization Brain Res. 962 2003 279 287
29. S.X. Li, L.J. Liu, W.G. Jiang, and L. Lu Morphine withdrawal produces circadian rhythm alterations of clock genes in mesolimbic brain areas and peripheral blood mononuclear cells in rats J. Neurochem. 109 2009 1668 1679
30. B.K. Madras, G.M. Miller, and A.J. Fischman The dopamine transporter and attention-deficit/hyperactivity disorder Biol. Psychiatry 57 2005 1397 1409
31. G. Paxinos, and K.J. Franklin The Mouse Brain in Stereotaxic Coordinates 2004 Elsevier Academic Press USA
32. C.A. McClung, K. Sidiropoulou, M. Vitaterna, J.S. Takahashi, F.J. White, D.C. Cooper, and E.J. Nestler Regulation of dopaminergic transmission and cocaine reward by the Clock gene Proc. Natl. Acad. Sci. USA 102 2005 9377 9381
33. H. Manev, and T. Uz Clock genes: influencing and being influenced by psychoactive drugs Trends Pharmacol. Sci. 27 2006 186 189
34. E.L. Mattiuz, G.D. Ponsler, R.J. Barbuch, P.G. Wood, J.H. Mullen, R.L. Shugert, Q. Li, W.J. Wheeler, F. Kuo, P.C. Conrad, and J.M. Sauer Disposition and metabolic fate of atomoxetine hydrochloride: pharmacokinetics, metabolism, and excretion in the Fischer 344 rat and beagle dog Drug Metab. Dispos 31 2003 88 97
35. C.A. McClung Circadian genes, rhythms and the biology of mood disorders Pharmacol. Ther. 114 2007 222 232
36. E.J. Nestler, and W.A. Carlezon Jr. The mesolimbic dopamine reward circuit in depression Biol. Psychiatry 59 2006 1151 1159
37. S.M. O'Keeffe, J. Thome, and A.N. Coogan The noradrenaline reuptake inhibitor atomoxetine phase-shifts the circadian clock in mice Neuroscience 201 2012 219 230
38. H. Pantazopoulos, H. Dolatshad, and F.C. Davis A fear-inducing odor alters PER2 and c-Fos expression in brain regions involved in fear memory PLoS One 6 2011 e20658
39. C. Ramanathan, A. Stowie, L. Smale, and A.A. Nunez Phase preference for the display of activity is associated with the phase of extra-suprachiasmatic nucleus oscillators within and between species Neuroscience 170 2010 758 772
40. S.M. Reppert, and D.R. Weaver Coordination of circadian timing in mammals Nature 418 2002 935 941
41. C. Rieux, R. Carney, D. Lupi, O. Dkhissi-Benyahya, K. Jansen, N. Chounlamountri, R.G. Foster, and HM. Cooper Analysis of immunohistochemical label of Fos protein in the suprachiasmatic nucleus: comparison of different methods of quantification J. Biol. Rhythms 17 2002 121 136
42. C.B. Saper, J. Lu, T.C. Chou, and J Gooley The hypothalamic integrator for circadian rhythms Trends Neurosci. 28 2005 152 157
43. J. Schaap, and J. Meijer Opposing effects of behavioural activity and light on neurons of the suprachiasmatic nucleus Eur. J. Neurosci. 13 2001 1955 1962
44. S. Schroeter, S. Apparsundaram, R.G. Wiley, L.H. Miner, S.R. Sesack, and R.D. Blakely Immunolocalization of the cocaine- and antidepressant-sensitive l- norepinephrine transporter J. Comp. Neurol. 420 2000 211 232
45. E. Sobanski, M. Schredl, N. Kettler, and B. Alm Sleep in adults with attention deficit hyperactivity disorder (ADHD) before and during treatment with methylphenidate: a controlled polysomnographic study Sleep 31 2008 375 381
46. M. Sofuoglu, J. Poling, K. Hill, and T. Kosten Atomoxetine attenuates dextroamphetamine effects in humans Am. J. Drug Alcohol Abuse 35 2009 412 416
47. H. Steiner, V. Van Waes, and M. Marinelli Fluoxetine potentiates methylphenidate-induced gene regulation in addiction-related brain regions: concerns for use of cognitive enhancers? Biol. Psychiatry 67 2010 592 594
48. D.L. Thai, L.N. Yurasits, G.R. Rudolph, and J.M. Perel Comparative pharmacokinetics and tissue distribution of the d-enantiomers of para-substituted methylphenidate analogs Drug Metab. Dispos 2 1999 645 650
49. T. Uz, R. Ahmed, M. Akhisaroglu, M. Kurtuncu, M. Imbesi, A. Dirim Arsan, and H. Manev Effect of fluoxetine and cocaine on the expression of clock genes in the mouse hippocampus and striatum Neuroscience 134 2005 1309 1316
50. P. Witkovsky Dopamine and retinal function Doc. Ophthalmol. 108 2004 17 40
51. P. Wongchitrat, M.P. Felder-Schmittbuhl, P. Phansuwan-Pujito, P. Pevet, and V. Simonneaux Endogenous rhythmicity of Bmal1 and Rev-erb alpha in the hamster pineal gland is not driven by norepinephrine Eur. J. Neurosci. 29 2009 2009 2016
52. C.A. Wyse, and A.N. Coogan Impact of aging on diurnal expression patterns of CLOCK and BMAL1 in the mouse brain Brain Res. 1337 2010 21 31