Towards an understanding of channelrhodopsin function: Simulations lead to novel insights of the channel mechanism

Journal of Molecular Biology

Volumn 425, Issue 10, 2013, Pages 1795-1814

  Watanabe, Hiroshi C ^a   Welke, Kai ^a   Sindhikara, Daniel J ^b   Hegemann, Peter ^c   Elstner, Marcus ^a  

^a KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

^b RITSUMEIKAN UNIVERSITY   (Japan)

^c HUMBOLDT UNIVERSITY   (Germany)

Author keywords

channelrhodopsin; microbial rhodopsin; molecular dynamics; optogenetics; QM MM simulation

Indexed keywords

CATION; CATION CHANNEL; CHANNELRHODOPSIN; CYSTINE; THREONINE; UNCLASSIFIED DRUG; WATER;

ARTICLE; BINDING SITE; CHANNEL GATING; COMPUTER ANALYSIS; HYDROGEN BOND; ION TRANSPORT; MOLECULAR MECHANICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTON TRANSPORT; SIMULATION; WATER TRANSPORT; X RAY CRYSTALLOGRAPHY;

ANIMALIA;

EID: 84877578341     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2013.01.033     Document Type: Article

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