Photocurrent attenuation by a single polar-to-nonpolar point mutation of channelrhodopsin-2

Photochemical and Photobiological Sciences

Volumn 8, Issue 3, 2009, Pages 328-336

  Sugiyama, Yuka ^a,b   Wang, Hongxia ^b   Hikima, Takuya ^b   Sato, Minami ^c   Kuroda, Jun ^c   Takahashi, Tetsuo ^c   Ishizuka, Toru ^b   Yawo, Hiromu ^a,b  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c TOHO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CHANNELRHODOPSIN 2; GLUTAMIC ACID; RHODOPSIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; CONTROLLED STUDY; FLUORESCENCE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; ION CURRENT; POINT MUTATION; PRIORITY JOURNAL; WILD TYPE;

ALGAE;

EID: 61649104837     PISSN: 1474905X     EISSN: 14749092     Source Type: Journal    
DOI: 10.1039/b815762f     Document Type: Article

References (43)

1. S. Kateriya G. Nagel E. Bamberg P. Hegemann "Vision" in single-celled algae News Physiol Sci 2004 19 133 137
2. M. Melkonian H. Robenek Eyespot membranes of Chlamydomonas reinhardii: a freeze-fracture study J Ultrastruct Res 1980 72 90 102
3. O. A. Sineshchekov K. H. Jung J. L. Spudich Two rhodopsins mediate phototaxis to low- and high-intensity light in Chlamydomonas reinhardtii Proc Natl Acad Sci U S A 2002 99 8689 8694
4. T. Suzuki K. Yamasaki S. Fujita K. Oda M. Iseki K. Yoshida M. Watanabe H. Daiyasu H. Toh E. Asamizu S. Tabata K. Miura H. Fukuzawa S. Nakamura T. Takahashi Archaeal-type rhodopsins in Chlamydomonas: model structure and intracellular localization Biochem Biophys Res Commun 2003 301 711 717
5. G. Nagel D. Ollig M. Fuhrmann S. Kateriya A. M. Musti E. Bamberg P. Hegemann Channelrhodopsin-1: a light-gated proton channel in green algae Science 2002 296 2395 2398
6. G. Nagel T. Szellas W. Huhn S. Kateriya N. Adeishvili P. Berthold D. Ollig P. Hegemann E. Bamberg Channelrhodopsin-2, a directly light-gated cation-selective membrane channel Proc Natl Acad Sci U S A 2003 100 13940 13945
7. G. Nagel T. Szellas S. Kateriya N. Adeishvili P. Hegemann E. Bamberg Channelrhodopsins: directly light-gated cation channels Biochem Soc Trans 2005 33 863 866
8. T. Ishizuka M. Kakuda R. Araki H. Yawo Kinetic evaluation of photosensitivity in genetically engineered neurons expressing green algae light-gated channels Neurosci Res 2006 54 85 94
9. X. Li D. V. Gutierrez M. G. Hanson J. Han M. D. Mark H. Chiel P. Hegemann L. T. Landmesser S. Herlitze Fast noninvasive activation and inhibition of neural and network activity by vertebrate rhodopsin and green algae channelrhodopsin Proc Natl Acad Sci U S A 2005 102 17816 17821
10. E. S. Boyden F. Zhang E. Bamberg G. Nagel K. Deisseroth Millisecond-timescale, genetically targeted optical control of neural activity Nat Neurosci 2005 8 1263 1268
11. P. Hegemann Algal sensory photoreceptors Annu Rev Plant Biol 2008 59 167 189
12. C. Bamann T. Kirsch G. Nagel E. Bamberg Spectral characteristics of the photocycle of channelrhodopsin-2 and its implication for channel function J Mol Biol 2008 375 686 694
13. O. P. Ernst P. A. Sanchez Murcia P. Daldrop S. P. Tsunoda S. Kateriya P. Hegemann Photoactivation of channelrhodopsin J Biol Chem 2008 283 1637 1643
14. F. Zhang M. Prigge F. Beyriere S. P. Tsunoda J. Mattis O. Yizhar P. Hegemann K. Deisseroth Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri Nat Neurosci 2008 11 631 633
15. L. Adamian Z. Ouyang Y. Y. Tseng J. Liang Evolutionary patterns of retinal-binding pockets of type I rhodopsins and their functions Photochem Photobiol 2006 82 1426 1435
16. E. Pebay-Peyroula A. Royant E. M. Landau J. Navarro Structural basis for sensory rhodopsin function Biochim Biophys Acta 2002 1565 196 205
17. P. Hegemann S. Ehlenbeck D. Gradmann Multiple photocycles of channelrhodopsin Biophys J 2005 89 3911 3918
18. J. K. Lanyi Mechanism of ion transport across membranes - bacteriorhodopsin as a prototype for proton pumps J Biol Chem 1997 272 31209 31212
19. R. Neutze E. Pebay-Peyroula K. Edman A. Royant J. Navarro E. M. Landau Bacteriorhodopsin: a high-resolution structural view of vectorial proton transport Biochim Biophys Acta 2002 1565 144 167
20. T. Mogi L. J. Stern T. Marti B. H. Chao H. G. Khorana Asparitic acid substitutions affect proton translocation by bacteriorhodopsin Proc Natl Acad Sci USA 1988 85 4148 4152
21. M. Kataoka H. Kamikubo F. Tokunaga L. S. Brown Y. Yamazaki A. Maeda M. Sheves R. Needleman J. K. Lanyi Energy coupling in an ion pump - the reprotonation switch of bacteriorhodopsin J Mol Biol 1994 243 621 638
22. L. S. Brown H. Kamikubo L. Zimányi M. Kataoka F. Tokunaga P. Verdegem J. Lugtenburg J. K. Lanyi A local electrostatic change is the cause of the large-scale protein conformation shift in bacteriorhodopsin Proc Natl Acad Sci USA 1997 94 5040 5044
23. P. Berthold S. P. Tsunoda O. P. Ernst W. Mages D. Gradmann P. Hegemann Channelrhodopsin-1 initiates phototaxis and photophobic responses in Chlamydomonas by immediate light-induced depolarization Plant Cell 2008 20 1665 1677
24. B. Hille, Ion channels of excitable membranes, third ed., Sinauer Associates, Massachusetts, USA, 2001
25. R. MacKinnon Pore loops: an emerging theme in ion channel structure Neuron 1995 14 889 892
26. G. Owsianik K. Talavera T. Voets B. Nilius Permeation and selectivity of TRP channels Annu Rev Physiol 2006 68 685 717
27. P. H. Seeburg F. Single T. Kuner M. Higuchi R. Sprengel Genetic manipulation of key determinants of ion flow in glutamate receptor channels in the mouse Brain Res 2001 907 233 243
28. M. H. Akabas D. A. Stauffer M. Xu A. Karlin Acetylcholine receptor channel structure probed in cysteine-substitution mutants Science 1992 258 307 310
29. H. Luecke B. Schobert J. K. Lanyi E. N. Spudich J. L. Spudich Crystal structure of sensory rhodopsin II at 2.4 angstroms: insights into color tuning and transducer interaction Science 2001 293 1499 1503
30. A. Miyazawa Y. Fujiyoshi N. Unwin Structure and gating mechanism of the acetylcholine receptor pore Nature 2003 423 949 955
31. D. Huber L. Petreanu N. Ghitani S. Ranade T. Hromadka Z. Mainen K. Svoboda Sparse optical microstimulation in barrel cortex drives learned behaviour in freely moving mice Nature 2008 451 61 64
32. S. J. Kuhlman Z. J. Huang High-resolution labeling and functional manipulation of specific neuron types in mouse brain by Cre-activated viral gene expression PLoS ONE 2008 3 e2005
33. L. Petreanu D. Huber A. Sobczyk K. Svoboda Channelrhodopsin-2-assisted circuit mapping of long-range callosal projections Nat Neurosci 2007 10 663 668
34. N. Toni D. A. Laplagne C. Zhao G. Lombardi C. E. Ribak F. H. Gage A. F. Schinder Neurons born in the adult dentate gyrus form functional synapses with target cells Nat Neurosci 2008 11 901 907
35. Y. P. Zhang T. G. Oertner Optical induction of synaptic plasticity using a light-sensitive channel Nat Methods 2007 4 139 141
36. G. Nagel M. Brauner J. F. Liewald N. Adeishvili E. Bamberg A. Gottschalk Light activation of channelrhodopsin-2 in excitable cells of Caenorhabditis elegans triggers rapid behavioral responses Curr Biol 2005 15 2279 2284
37. A. D. Douglass S. Kraves K. Deisseroth A. F. Schier F. Engert Escape behavior elicited by single, channelrhodopsin-2-evoked spikes in zebrafish somatosensory neurons Curr Biol 2008 18 1133 1137
38. B. R. Arenkiel J. Peca I. G. Davison C. Feliciano K. Deisseroth G. J. Augustine M. D. Ehlers G. Feng In vivo light-induced activation of neural circuitry in transgenic mice expressing channelrhodopsin-2 Neuron 2007 54 205 218
39. A. Bi J. Cui Y. P. Ma E. Olshevskaya M. Pu A. M. Dizhoor Z. H. Pan Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration Neuron 2006 50 23 33
40. S. Herlitze L. T. Landmesser New optical tools for controlling neuronal activity Curr Opin Neurobiol 2007 17 87 94
41. P. S. Lagali D. Balya G. B. Awatramani T. A. Munch D. S. Kim V. Busskamp C. L. Cepko B. Roska Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration Nat Neurosci 2008 11 667 675
42. H. Tomita E. Sugano H. Yawo T. Ishizuka H. Isago S. Narikawa S. Kügler M. Tamai Restoration of visual response in aged dystrophic RCS rats using AAV-mediated channelopsin-2 gene transfer Invest Ophthalmol Vis Sci 2007 48 3821 3826
43. H. Wang Y. Sugiyama T. Hikima E. Sugano H. Tomita T. Takahashi T. Ishizuka H. Yawo J. Biol. Chem. 10.1074/jbc.M807632200