Ucf-101 protects against cerebral oxidative injury and cognitive impairment in septic rat

International Immunopharmacology

Volumn 16, Issue 1, 2013, Pages 108-113

  Hu, Yueyu ^a   Huang, Man ^a   Wang, Pengfei ^a   Xu, Qiuping ^a   Zhang, Baorong ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Cognitive impairment; Omi HtrA2; Oxidative stress; Sepsis; UCF 101

Indexed keywords

ANTIOXIDANT; CASPASE 3; CASPASE 9; MALONALDEHYDE; NEUROPROTECTIVE AGENT; SERINE PROTEINASE INHIBITOR; SERINE PROTEINASE OMI; TUMOR NECROSIS FACTOR ALPHA; UCF 101; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN INJURY; CELL POPULATION; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE ACTIVITY; ENZYME ACTIVITY; IN VITRO STUDY; LATENT PERIOD; LEARNING; LIPID PEROXIDATION; MALE; MEMORY; MEMORY DISORDER; MOTOR ACTIVITY; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PERITONEAL CAVITY; PRIORITY JOURNAL; RAT; SEPSIS; SPATIAL LEARNING; SURVIVAL RATE; SURVIVAL TIME; SWIMMING; WEIGHT REDUCTION;

ANIMALS; APOPTOSIS; BRAIN DISEASES; CASPASE 3; CASPASE 9; COGNITION DISORDERS; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PYRIMIDINONES; RATS; RATS, SPRAGUE-DAWLEY; SEPSIS; THIONES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84877577777     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2013.03.019     Document Type: Article

References (39)

1. P.M. Klein Klouwenberg, D.S. Ong, M.J. Bonten, and O.L. Cremer Classification of sepsis, severe sepsis and septic shock: the impact of minor variations in data capture and definition of SIRS criteria Intensive Care Med 38 5 May 2012 811 819
2. M. Bhatia, and S. Moochhala Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome J Pathol 202 2 Feb 2004 145 156
3. D.D. Melley, T.W. Evans, and G.J. Quinlan Redox regulation of neutrophil apoptosis and the systemic inflammatory response syndrome Clin Sci (Lond) 108 5 May 2005 413 424
4. H. Sebai, W. Gadacha, M. Sani, E. Aouani, N. Ghanem-Boughanmi, and M. Ben-Attia Protective effect of resveratrol against lipopolysaccharide-induced oxidative stress in rat brain Brain Inj 23 13-14 Dec 2009 1089 1094
5. T.E. Gofton, and G.B. Young Sepsis-associated encephalopathy Nat Rev Neurol 8 10 Oct 2012 557 566
6. M.S. Bhuiyan, and K. Fukunaga Mitochondrial serine protease HtrA2/Omi as a potential therapeutic target Curr Drug Targets 10 4 Apr 2009 372 383
7. X. Ding, M. Patel, D. Shen, A.A. Herzlich, X. Cao, and R. Villasmil Enhanced HtrA2/Omi expression in oxidative injury to retinal pigment epithelial cells and murine models of neurodegeneration Invest Ophthalmol Vis Sci 50 10 Oct 2009 4957 4966
8. L. Cilenti, Y. Lee, S. Hess, S. Srinivasula, K.M. Park, and D. Junqueira Characterization of a novel and specific inhibitor for the pro-apoptotic protease HtrA2/Omi J Biol Chem 278 2003 11489 11494
9. H.R. Liu, E. Gao, A. Hu, L. Tao, Y. Qu, and P. Most Role of Omi/HtrA2 in apoptotic cell death after myocardial ischemia and reperfusion Circulation 111 1 Jan 4 2005 90 96
10. J. Kim, D.S. Kim, M.J. Park, H.J. Cho, A.S. Zervos, and J.V. Bonventre Omi/HtrA2 protease is associated with tubular cell apoptosis and fibrosis induced by unilateral ureteral obstruction Am J Physiol Renal Physiol 298 6 Jun 2010 F1332 F1340
11. D. Su, Z. Su, J. Wang, S. Yang, and J. Ma UCF-101, a novel Omi/HtrA2 inhibitor, protects against cerebral ischemia/reperfusion injury in rats Anat Rec (Hoboken) 292 6 Jun 2009 854 861
12. Q.B. Liu, L.L. Liu, Y.M. Lu, R.R. Tao, J.Y. Huang, and F. Han The induction of reactive oxygen species and loss of mitochondrial Omi/HtrA2 is associated with S-nitrosoglutathione-induced apoptosis in human endothelial cells Toxicol Appl Pharmacol 244 3 May 1 2010 374 384
13. T. Barichello, M.R. Martins, A. Reinke, G. Feier, C. Ritter, and J. Quevedo Cognitive impairment in sepsis survivors from cecal ligation and perforation Crit Care Med 33 1 Jan 2005 221 223
14. G. Paxinos, and C. Watson The rat brain: stereotaxic coordinates 2nd ed. 1986 Academic Press Australia
15. M. Mihara, and M. Uchiyama Determination of malonaldehyde precursor in tissues by thiobarbituric acid test Anal Biochem 86 1 May 1978 271 278
16. H. Aebi Catalase in vitro Methods Enzymol 105 1984 121 126
17. C.V. Vorhees, and M.T. Williams Morris water maze: procedures for assessing spatial and related forms of learning and memory Nat Protoc 1 2 2006 848 858
18. W. Stenzel, S. Soltek, H. Miletic, M.M. Hermann, H. Korner, and J.D. Sedgwick An essential role for tumor necrosis factor in the formation of experimental murine Staphylococcus aureus-induced brain abscess and clearance J Neuropathol Exp Neurol 64 2005 27 36
19. M. Ziaja Sepsis and septic encephalopathy: characteristics and experimental models Folia Neuropathol 50 3 2012 231 239
20. J.A. Frontera Metabolic encephalopathies in the critical care unit Continuum (Minneap Minn) 18 3 Jun 2012 611 639
21. L.N. Zhang, X.T. Wang, Y.H. Ai, Q.L. Guo, L. Huang, and Z.Y. Liu Epidemiological features and risk factors of sepsis-associated encephalopathy in intensive care unit patients: 2008-2011 Chin Med J (Engl) 125 5 Mar 2012 828 831
22. G. Wang, W. Wang, J. Zhao, Y. Ni, X. Zhou, and W. Zhang Ghrelin prevents neuronal apoptosis and cognitive impairments in sepsis-associated encephalopathy Neuroreport 22 18 Dec 21 2011 959 964
23. G.L. Wenk Assessment of spatial memory using the radial arm maze and Morris water maze Curr Protoc Neurosci May 2004 (Chapter 8:Unit 8.5A)
24. M.L. Gunther, A. Morandi, E. Krauskopf, P. Pandharipande, T.D. Girard, and J.C. Jackson The association between brain volumes, delirium duration, and cognitive outcomes in intensive care unit survivors: the VISIONS cohort magnetic resonance imaging study Crit Care Med 40 7 Jul 2012 2022 2032
25. J. Zhou, Y. Chen, G.Q. Huang, J. Li, G.M. Wu, and L. Liu Hydrogen-rich saline reverses oxidative stress, cognitive impairment, and mortality in rats submitted to sepsis by cecal ligation and puncture J Surg Res 178 1 Nov 2012 390 400
26. L. Crews, and E. Masliah Molecular mechanisms of neurodegeneration in Alzheimer's disease Hum Mol Genet 19 R1 Apr 15 2010 R12 R20
27. C.M. Comim, T. Barichello, D. Grandgirard, F. Dal-Pizzol, J. Quevedo, and S.L. Leib Caspase-3 mediates in part hippocampal apoptosis in sepsis Mol Neurobiol 47 1 Feb 2013 394 398
28. Z.L. Chen, and S. Strickland Neuronal death in the hippocampus is promoted by plasmin-catalyzed degradation of laminin Cell 91 1997 917 925
29. S.L. Leib, Y.S. Kim, L.L. Chow, R.A. Sheldon, and M.G. Täuber Reactive oxygen intermediates contribute to necrotic and apoptotic neuronal injury in an infant rat model of bacterial meningitis due to group B streptococci J Clin Invest 98 1996 2632 2639
30. A.G. Yakovlev, S.M. Knoblach, L. Fan, G.B. Fox, R. Goodnight, and A.I. Faden Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury J Neurosci 17 1997 7415 7424
31. Q.L. Deveraux, and J.C. Reed IAP family proteins - suppressors of apoptosis Genes Dev 13 1999 239 252
32. L.M. Martins The serine protease Omi/HtrA2: a second mammalian protein with a Reaper-like function Cell Death Differ 9 2002 699 701
33. L. Cilenti, G.A. Kyriazis, M.M. Soundarapandian, V. Stratico, A. Yerkes, and K.M. Park Omi/HtrA2 protease mediates cisplatin-induced cell death in renal cells Am J Physiol Renal Physiol 288 2 Feb 2005 F371 F379
34. D. Goffredo, D. Rigamonti, C. Zuccato, M. Tartari, M. Valenza, and E. Cattaneo Prevention of cytosolic IAPs degradation: a potential pharmacological target in Huntington's Disease Pharmacol Res 52 2 Aug 2005 140 150
35. K. Klupsch, and J. Downward The protease inhibitor Ucf-101 induces cellular responses independently of its known target, HtrA2/Omi Cell Death Differ 13 2006 2157 2159
36. H. Zhang, A.S. Slutsky, and J.L. Vincent Oxygen free radicals in ARDS, septic shock and organ dysfunction Intensive Care Med 26 2000 474 476
37. T. Barichello, J.J. Fortunato, A.M. Vitali, G. Feier, A. Reinke, and J.C. Moreira Oxidative variables in the rat brain after sepsis induced by cecal ligation and perforation Crit Care Med 34 3 Mar 2006 886 889
38. G. Ray, and S.A. Husain Oxidants, antioxidants and carcinogenesis Indian J Exp Biol 40 11 Nov 2002 1213 1232
39. C.M. Comim, G.T. Rezin, G. Scaini, P.B. Di-Pietro, M.R. Cardoso, and F.C. Petronilho Mitochondrial respiratory chain and creatine kinase activities in rat brain after sepsis induced by cecal ligation and perforation Mitochondrion 8 4 Sep 2008 313 318