Post-ischaemic thyroid hormone treatment in a rat model of acute stroke

Brain Research

Volumn 1513, Issue , 2013, Pages 92-102

  Genovese, Tiziana ^a   Impellizzeri, Daniela ^b   Ahmad, Akbar ^b   Cornelius, Carolin ^c   Campolo, Michela ^b   Cuzzocrea, Salvatore ^b,d   Esposito, Emanuela ^b  

^a UNIVERSITY OF MESSINA   (Italy)

^b UNIVERSITY OF MESSINA   (Italy)

^c UNIVERSITY OF CATANIA   (Italy)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Cerebral ischaemia; l Thyroxine; Neuroprotection; Thyroid hormone

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLOOXYGENASE 2; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUROPROTECTIVE AGENT; NEUROTROPHIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE C GAMMA; THYROXINE; ACTIN BINDING PROTEIN; AIF1 PROTEIN, RAT; CALCIUM BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BRAIN INFARCTION; BRAIN INJURY; BRAIN ISCHEMIA; CONTROLLED STUDY; DOWN REGULATION; INFLAMMATORY CELL; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; ANIMAL; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; INFARCTION, MIDDLE CEREBRAL ARTERY; METABOLISM; NEUROLOGIC EXAMINATION; PATHOLOGY; PHYSIOLOGY; REPERFUSION; WISTAR RAT;

RATTUS;

ANIMALS; BRAIN INFARCTION; BRAIN-DERIVED NEUROTROPHIC FACTOR; CALCIUM-BINDING PROTEINS; CYCLOOXYGENASE 2; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MICROFILAMENT PROTEINS; NEUROLOGIC EXAMINATION; NITRIC OXIDE SYNTHASE TYPE II; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR; REPERFUSION; THYROXINE;

EID: 84877574996     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2013.03.001     Document Type: Article

References (54)

1. M. Alevizaki, M. Synetou, K. Xynos, C.C. Alevizaki, and K.N. Vemmos Hypothyroidism as a protective factor in acute stroke patients Clin. Endocrinol. 65 2006 369 372
2. J.B. Bederson Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats Stroke 17 1986 1304 1308
3. J. Bernal Thyroid hormone receptors in brain development and function Nat. Clin. Pract. Endocrinol. Metab. 3 2007 249 259
4. T.L. Butler, C.A. Kassed, P.R. Sanberg, A.E. Willing, and K.R. Pennypacker Neurodegeneration in the rat hippocampus and striatum after middle cerebral artery occlusion Brain Res. 929 2002 252 260
5. A. Céspedes-Rubio, F.W. Jurado, and G.P. Cardona-Gómez p120 catenin/αN-catenin are molecular targets in the neuroprotection and neuronal plasticity mediated by atorvastatin after focal cerebral ischemia J. Neurosci. Res. 88 2010 3621 3634
6. J.P. Chanoine, L.E. Braverman, A.P. Farwell, M. Safran, S. Alex, S. Dubord, and J.L. Leonard The thyroid gland is a major source of circulating T3 in the rat J. Clin. Invest. 91 1993 2709 2713
7. S.Y. Cheng, J.L. Leonard, and P.J. Davis Molecular aspects of thyroid hormone actions Endocr. Rev. 31 2010 139 170
8. W.H. Chou, D.S. Choi, H. Zhang, D. Mu, T. McMahon, V.N. Kharazia, C.A. Lowell, D.M. Ferriero, and R.O. Messing Neutrophil protein kinase Cdelta as a mediator of stroke-reperfusion injury J. Clin. Invest. 114 2004 49 56
9. P. Davis New insights into thyroid hormone actions and lipid metabolism Curr. Opin. Endocrinol. Diabetes Obes. 17 2010 395
10. P.J. Davis Integrated nongenomic and genomic actions of thyroid hormone on blood vessels Curr. Opin. Endocrinol. Diabetes Obes. 18 2011 293 294
11. P.J. Davis, and F.B. Davis Nongenomic actions of thyroid hormone L.E. Braverman, Diseases of the Thyroid second ed. 2003 Humana Press Totowa, NJ 19 37
12. P.J. Davis, A. Shih, H.-Y. Lin, L.J. Martino, and F.B. Davis Thyroxine promotes association of mitogen-activated protein kinase and nuclear thyroid hormone receptor (TR) and causes serine phosphorylation of TR J. Biol. Chem. 275 2000 38032 38039
13. R.J. Davis The mitogen-activated protein kinase signal transduction pathway J. Biol. Chem. 268 1993 14553 14556
14. S. Diano, J.L. Leonard, R. Meli, E. Esposito, and L. Schiavo Hypothalamic type II iodothyronine deiodinase: a light and electron microscopic study Brain Res. 976 2003 130 134
15. U. Dirnagl, C. Iadecola, and M.A. Moskowitz Pathobiology of ischaemic stroke: an integrated view Trends Neurosci. 22 1999 391 397
16. A.P. Farwell, S.A. Dubord-Tomasetti, A.Z. Pietrzykowski, and J.L. Leonard Dynamic nongenomic actions of thyroid hormone in the developing rat brain Endocrinology 147 2006 2567 2574
17. V. Fernández, G. Tapia, P. Varela, P. Cornejo, and L.A. Videla Upregulation of liver inducible nitric oxide synthase following thyroid hormone preconditioning: suppression by N-acetylcysteine Biol. Res. 42 4 2009 487 495
18. J.H. Garcia Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Statistical validation Stroke 26 1995 627 634 discussion 635
19. J. Guo, D.N. Krause, J. Horne, J.H. Weiss, X. Li, and S.P. Duckles Estrogen-receptor-mediated protection of cerebral endothelial cell viability and mitochondrial function after ischemic insult in vitro J. Cereb. Blood Flow Metab. 30 2010 545 554
20. H. Hara Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage PNAS 94 1997 2007 2012
21. K.-A. Hossmann Pathophysiology and therapy of experimental stroke Cell. Mol. Neurobiol. 26 2006 1055 1081
22. C.H. Lee, K.Y. Yoo, I.K. Hwang, J.H. Choi, O.K. Park, H. Li, I.J. Kang, Y.G. Kwon, Y.M. Kim, and M.H. Won Hypothyroid state does not protect but delays neuronal death in the hippocampal CA1 region following transient cerebral ischemia: focus on oxidative stress and gliosis J. Neurosci. Res. 88 2010 2661 2668
23. H.Y. Lin, F.B. Davis, J.K. Gordinier, L.J. Martino, and P.J. Davis Thyroid hormone induces activation of mitogen-activated protein kinase in cultured cells Am. J. Physiol. 276 1999 C1014 C1024
24. Lin, H.Y., Sun, M., Tang, H.Y., Lin, C., Luidens, M.K., Mousa, S.A., Incerpi, S., Drusano, G.L., Davis, F.B., Davis, P.J. l-Thyroxine vs. 3,5,3′-triiodo-l-thyronine and cell proliferation: activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase. Am. J. Physiol. Cell. Physiol. 296, 2009, C980-91.
25. H.Y. Lin, F.B. Davis, M.K. Luidens, S.A. Mousa, J.H. Cao, M. Zhou, and P.J. Davis Molecular basis for certain neuroprotective effects of thyroid hormone Front. Mol. Neurosci. 4 2011 29
26. E.Z. Longa Reversible middle cerebral artery occlusion without craniectomy in rats Stroke 20 1989 84 91
27. G. Losi, G. Garzon, and G. Puia Nongenomic regulation of glutamatergic neurotransmission in hippocampus by thyroid hormones Neuroscience 151 2008 155 163
28. X.C. Lu Post-treatment with a novel PARG inhibitor reduces infarct in cerebral ischemia in the rat Brain Res. 978 2003 99 103
29. H.G. Lüesse, T. Roskoden, R. Linke, U. Otten, K. Heese, and H. Schwegler Modulation of mRNA expression of the neurotrophins of the nerve growth factor family and their receptors in the septum and hippocampus of rats after transient postnatal thyroxine treatment. I. Expression of nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin 4 mRNA Exp. Brain Res. 119 1 1998 1 8
30. K. Mandai Ischemic damage and subsequent proliferation of oligodendrocytes in focal cerebral ischemia Neuroscience 77 1997 849 861
31. I. Margaill, J. Royer, D. Lerouet, M. Ramaugé, C. Le Goascogne, W.W. Li, M. Plotkine, M. Pierre, and F. Courtin Induction of type 2 iodothyronine deiodinase in astrocytes after transient focal cerebral ischemia in the rat J. Cereb. Blood Flow Metab. 25 2005 468 476
32. M.P. Mattson, W. Duan, W.A. Pedersen, and C. Culmsee Neurodegenerative disorders and ischemic brain diseases Apoptosis 6 2001 69 81
33. A. Melani Striatal outflow of adenosine, excitatory amino acids, gamma-aminobutyric acid, and taurine in awake freely moving rats after middle cerebral artery occlusion: correlations with neurological deficit and histopathological damage Stroke 30 1999 2448 2454 discussion 2455
34. A. Melani Selective adenosine A2a receptor antagonism reduces JNK activation in oligodendrocytes after cerebral ischaemia Brain 132 2009 1480 1495
35. C.B. Mendes-de-Aguiar, R. Alchini, H. Decker, M. Alvarez-Silva, C.I. Tasca, and A.G. Trentin Thyroid hormone increases astrocytic glutamate uptake and protects astrocytes and neurons against glutamate toxicity J. Neurosci. Res. 86 2008 3117 3125
36. A.A. Mongin Disruption of ionic and cell volume homeostasis in cerebral ischemia: the perfect storm Pathophysiology 2007 14 2007 183 193
37. K. Nozaki, M. Nishimura, and N. Hashimoto Mitogen-activated protein kinases and cerebral ischemia Mol. Neurobiol. 23 2001 1 19
38. C.K. Petito, and I.A. Halaby Relationship between ischemia and ischemic neuronal necrosis to astrocyte expression of glial fibrillary acidic protein Int. J. Dev. Neurosci. 11 1993 239 247
39. A. Rami, and J. Krieglstein Thyroxine attenuates hippocampal neuronal damage caused by ischemia in the rat Life Sci. 50 1992 645 650
40. L. Rastogi, M.M. Godbole, M. Ray, P. Rathore, P. Rathore, S. Pradhan, S.K. Gupta, and C.M. Pandey Reduction in oxidative stress and cell death explains hypothyroidism induced neuroprotection subsequent to ischemia/reperfusion insult Exp. Neurol. 200 2 2006 290 300
41. A. Richard Green, T. Odergren, and T. Ashwood Animal models of stroke: do they have value for discovering neuroprotective agents? Trends Pharmacol. Sci. 24 2003 402 408
42. W. Rosamond, K. Flegalm, G. Friday, K. Furie, A. Go, K. Greenlund, N. Haase, M. Ho, V. Howard, B. Kissela, S. Kittner, D. Lloyd-Jones, M. McDermott, J. Meigs, C. Moy, G. Nichol, C.J. O'Donnell, V. Roger, J. Rumsfeld, P. Sorlie, J. Steinberger, T. Thom, S. Wasserthiel-Smoller, and Y. Hong American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics-2007 update: a report from the American heart association statistics committee and stroke statistics subcommittee Circulation 115 2007 e69 e171
43. G. Sárközy, E. Griesmaier, X. He, K. Kapelari, M. Urbanek, G. Simbruner, P. Gressens, and M. Keller T3 replacement does not prevent excitotoxic cell death but reduces developmental neuronal apoptosis in newborn mice Eur. J. Paediatr. Neurol. 11 2007 129 135
44. S. Scapin, S. Leoni, S. Spagnuolo, D. Gnocchi, P. De Vito, P. Luly, J.Z. Pedersen, and S. Incerpi Short-term effects of thyroid hormones during development: focus on signal transduction Steroids 75 8-9 2010 576 584
45. E.H. Schlenker, M. Hora, Y. Liu, R.A. Redetzke, E. Morkin, and A.M. Gerdes Effects of thyroidectomy, T4, and DITPA replacement on brain blood vessel density in adult rats Am. J. Physiol. Regul. Integr. Comp. Physiol. 294 2008 R1504 R1509
46. M. Schomacher Endocannabinoids mediate neuroprotection after transient focal cerebral ischemia Brain Res. 1240 2008 213 220
47. A. Shih, H.-Y. Lin, F.B. Davis, and P.J. Davis Thyroid hormone promotes serine phosphorylation of p53 by mitogen-activated protein kinase Biochemistry 40 2001 2870 2878
48. A. Shuaib, S. Ijaz, R. Mazagri, J. Kalra, S. Hemmings, A. Senthilsvlvan, and N. Crosby Hypothyroidism protects the brain during transient forebrain ischemia in gerbils Exp. Neurol. 127 1994 119 125
49. C.A. Siegrist-Kaiser, C. Juge-Aubry, M.P. Tranter, D.M. Ekenbarger, and J.L. Leonard Thyroxine-dependent modulation of actin polymerization in cultured astrocytes. A novel, extranuclear action of thyroid hormone J. Biol. Chem. 265 1990 5296 5302
50. T. Takano, N. Oberheim, M.L. Cotrina, and M. Nedergaard Astrocytes and ischemic injury Stroke 40 2009 S8 S12
51. H.Y. Tang, H.Y. Lin, S. Zhang, F.B. Davis, and P.J. Davis Thyroid hormone causes mitogen-activated protein kinase-dependent phosphorylation of the nuclear estrogen receptor Endocrinology 145 2004 3265 3272
52. D.-C. Wu, W. Ye, X.-M. Che, and G.-Y. Yang Activation of mitogen-activated protein kinases after permanent cerebral artery occlusion in mouse brain J. Cereb. Blood. Flow. Metab. 20 2000 1320 1330
53. M.A. Yonkers, and A.B. Ribera Sensory neuron sodium current requires nongenomic actions of thyroid hormone during development J. Neurophysiol. 100 2008 2719 2725
54. W. Zhang, C. Smith, A. Shapiro, R. Monette, J. Hutchison, and D. Stanimirovic Increased expression of bioactive chemokines in human cerebromicrovascular endothelial cells and astrocytes subjected to simulated ischemia in vitro J. Neuroimmunol. 101 1999 148 160