Reduction in oxidative stress and cell death explains hypothyroidism induced neuroprotection subsequent to ischemia/reperfusion insult

Experimental Neurology

Volumn 200, Issue 2, 2006, Pages 290-300

  Rastogi, Leena ^a   Godbole, Madan M ^a   Ray, Madhur ^b   Rathore, Priyanka ^b   Pradhan, Sunil ^a   Gupta, Sushil K ^a   Pandey, Chandra M ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

^b CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Apoptosis; Hypothyroidism; Necrosis; Oxidative stress; Stroke

Indexed keywords

LACTATE DEHYDROGENASE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BRAIN INFARCTION; BRAIN ISCHEMIA; BRAIN MITOCHONDRION; BRAIN NECROSIS; BRAIN REGION; CELL DEATH; DISEASE MARKER; ENZYME ACTIVITY; ENZYME CHEMISTRY; FLOW CYTOMETRY; HYPOTHYROIDISM; MALE; MEMBRANE POTENTIAL; MIDDLE CEREBRAL ARTERY OCCLUSION; MITOCHONDRIAL MEMBRANE; NERVE CELL LESION; NEUROLOGIC DISEASE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REPERFUSION INJURY;

ANIMALS; BRAIN INFARCTION; CALCIUM; CATALASE; CELL DEATH; DISEASE MODELS, ANIMAL; HYPOTHYROIDISM; IMIDAZOLES; IN SITU NICK-END LABELING; LIPID PEROXIDATION; MALE; NADP; NEUROLOGIC EXAMINATION; NEUROPROTECTIVE AGENTS; NITRITES; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY; TETRAZOLIUM SALTS;

EID: 33746305919     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2006.02.013     Document Type: Article

References (46)

1. Aebi A. Catalase activity. In: Bergmeiste H.V. (Ed). Methods of enzymatic analysis vol. 3 (1974), Academic Press, New York 673-683
2. Ahamed S.H., Yong Y.He., Nasselef A., Xu J., Xu X.M., and Chung Y. Effects of lipopolysaccharide priming on acute ischemic brain injury. Stroke 31 (2000) 193-199
3. Alevizaki M., Synetou M., Xynos K., and Vemmos K. Hypothyroidism is associated with improved outcome in patients with acute stroke. Thyroid 15 (2005) S-11, O 29 (Abstract)
4. Baker K., Marcus C.B., Huffman K., Kruk H., Malfroy B., and Doctrow S.R. Synthetic combined superoxide dismutase/catalase mimetic are protective as a delayed treatment in a rat stroke model: a key role for reactive oxygen species in ischemic injury. J. Pharmacol. Exp. Ther. 284 (1998) 215-221
5. Barone F.C., Hillegass L.M., Price W.J., White R.F., Feuerstein G.Z., Sarau H.M., Clark R.K., and Griswold D.E. Polymorph nuclear leukocyte infiltration into cerebral focal ischemic tissue. Myeloperoxidase activity assay and histological verification. J. Neurosci. Res. 29 (1991) 336-348
6. Baxter G.F., and Ferdinandy P. Delayed preconditioning of myocardia: current prospective. Basic Res. Cardiol. 96 (2001) 329-344
7. Bederson J.B., Petts L.H., Germano S.M., Nishimura M.C., Davis R.L., and Bartkowski H.M. Evaluation of 2,3,5-tri phenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infraction in rats. Stroke 17 (1986) 1304-1308
8. Chance B., and Balcheffsky H. Respiratory enzymes in oxidative phosphorylation. J. Biol. Chem. 233 (1958) 736-739
9. Chopra I.J. Nonthyroidal illness syndrome or euthyroid sick syndrome?. Endocr. Pract. 2 (1996) 34-41
10. Coimbra C., Drake M., Boris-Moiller F., Wieloch T., and Long. Lasting neuroprotective effect of postischemic hypothermia and treatment with anti-inflammatory/antipyretic drug. Stroke 27 (1996) 1578-1585
11. Constant E.L., Volder A.G., Ivanoiu A., Bol A., Labar D., Seghers A., Cosnard G., Melin J., and Daumerie C. Cerebral blood flow and glucose metabolism in hypothyroidism: a positron emission tomography study. J. Clin. Endocrinol. Metab. 86 8 (2001) 3864-3870
12. Emaus R.K., Grunwald R., and Lemasters J.J. Rhodamine 123 is a probe of transmembrane potential in isolated rat liver mitochondria: spectral and metabolic properties. Biochim. Biophys. Acta 850 (1986) 436-448
13. Fassbender K., Fater M., Ragoschke A., Picard M., Bertsch T., Kuchl S., and Hennerici M. Sub acute but not acute generation of nitric oxide in focal cerebral ischemia. Stroke 31 (2000) 2208-2211
14. Ferdinand P., Szilvassy Z., and Baxter G.F. Adaptation to myocardial stress in disease states: is preconditioning a healthy heart phenomenon?. Trends Pharmacol Sci. 19 (1998) 223-229
15. Freichs K.V., Lindsberg P.J., Hallenbeck J.M., and Feuerstein G.Z. Increased cerebral lactate output to cerebral venous blood after forebrain ischemia in rats. Stroke 21 (1990) 614-617
16. Galinames M., Somolenski R.T., and Haddock P.S. Early effects of hypothyroidism on contractile function of the rat heart and its tolerance to hypothermic ischemia. J. Thorac. Cardiovas. Surg. 107 (1994) 829-837
17. Guanasekhar P.G., Kanthasamy A.G., Borowitz J.L., and Isom G.E. NMDA receptor activation produces concurrent generation of nitric oxide and reactive oxygen species: implication to cell death. J. Neurochem. 65 (1995) 2016-2021
18. Kader A., Frazzini V.I., Christopher B.J., Solomon R.A., and Trifiletti R.R. Effect of mild hypothermia on nitric oxide synthesis during focal cerebral ischemia. Neurosurgery 35 (1994) 272-277
19. Kakkar P., Das B., and Vishwanthan P.N. A modified spectrophotometric assay of Superoxide dismutase. Ind. J. Biochm. Biophys. 21 (1984) 130-132
20. Keller J.N., Kindy M.S., and Holltsberg F.W. Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction. J. Neurosci. 18 (1998) 687-697
21. Kiloto M., Monnier J., Chersown S.E., Raizada M.K., and Nick H.S. Regulation of the magnese superoxide dismutase and inducible nitric oxide synthase generated neuronal and glial cells. J. Neurochem. 66 (1996) 2128-2135
22. Kitagawa K., Mastumoto M., and Tagaya M. Ischemic tolerance phenomenon found in the brain. Brain Res. 528 (1990) 21-24
23. Kristian T., and Siesjo B.K. Calcium related damage in ischemia. Life Sci. 59 (1996) 357-367
24. Kristian T., and Siesjo B.K. Calcium in ischemic cell death. Stroke 29 (1998) 705-708
25. Kontos H.A. Oxygen radicals in cerebral ischemia. The 2001 Willis Lecture. Stroke 32 (2001) 2712-2716
26. Lai J.C.K., and Clark J.B. Isolation and characterization of synaptic and postsynaptic mitochondria from mammalian brain. In: Boulten G.A., Baker G.B., and Butterworth R.F. (Eds). Neuromethods vol. 11 (1990), Human Press, Cross, NJ 133-163
27. Leker R.R., Teichner A., Ovadia H., Keshet E., Reinherz E., and Hur T. Expression of endothelial nitric oxide synthase in the ischemic penumbra: relationship to expression of neuronal nitric oxide synthase and vascular endothelial growth factor. Brain Res. 909 (2001) 1-7
28. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R. Protein measurement with the folin phenol reagent. J. Biol. Chem. 193 (1951) 265-275
29. Luan X., Li J., McAllister J.P., Diaz F.G., Clark J.C., Fessler R.D., and Ding Y. Regional brain cooling induced by vascular saline infusion into ischemic territory reduces brain inflammation in stroke. Acta Neuropathol. 201 (2003) 45-51
30. Okhawa H., Ohishi N., and Yagi K. Assay for lipid peroxides in animal tissue by thiobarbituric acid reaction. Anal. Biochem. 95 (1979) 351-358
31. 2+ of brain neurons: a technical aspect. Brain Res. 728 (1996) 121-124
32. Paller M.S., and Sikova J.J. Hypothyroidism protects against free radical damage in ischemic acute renal failure. Kidney Int. 29 (1986) 1162-1166
33. Przykleux K., and Kloner R.A. Ischemic preconditioning: exploring the paradox. Prog. Cardiovas. Dis. 40 (1998) 517-547
34. Reed J.S., Hirano T., Davis S.M., and Dannon G.A. Limiting neurological damage after stroke. Drugs Aging 14 (1999) 11-39
35. Rehncrona S., Rosen I., and Siesjo B.K. Brain lactic acidosis and ischemic cell damage: biochemistry and neurophysiology. J. Cereb. Blood Flow Metab. 1 (1981) 297-311
36. Shuaib A., Ijaz S., Hemmings S., and Kalra J. Hypothyroidism protects the brain during transient forebrain ischemia. Can. J. Neurol. Sci. 20 (1993) 577-581
37. Shuaib A., Ijaj S., and Hemmings S. Decreased glutamate release during hypothyroidism may contribute to protection in ischemia. Exp. Neurol. 128 (1994) 260-265
38. Singh I. Lovastatin and phenyl acetate inhibits the induction of NOS and cytokines in rat primary astrocyte microglia and macrophage. J. Clin. Invest. 261 (1997) 100-111
39. Sinha A.K., Prabhakaran D., and Godbole M.M. Thyroid hormone and human fetal brain. In: Hendrich C.E. (Ed). Recent Res. Dev. Neuroendocrinology Thyroid Hormone and Brain Maturation, Research Signpost (1997) 1-14
40. Sterling K., Milch P.O., and Brenner M.A. Thyroid hormone action: the mitochondrial pathway. Science 197 (1977) 996-999
41. Sureda F.X., Camins A., Trullas R., and Camarasa J. A flow cytometric study of N-methyl-d-aspartate effects on dissociated cerebellar cells. Brain Res. 723 (1996) 110-114
42. Swaroop A., and Ramasarma T. Heat exposure and hypothyroid condition decreases hydrogen peroxide generation in liver mitochondria. Biochem. J. 226 (1985) 403-408
43. Yam J., and Roberts R.J. Pharmacological alteration of oxygen induced lung toxicity. Toxicol. Appl. Pharmacol. 47 (1979) 367-375
44. Zea-Longa E., Weinstein P.R., Carlson S., and Cummins R. Reversible middle artery occlusion without craniotomy in rats. Stroke 20 (1989) 84-91
45. Zaiden E., and Sims N.R. The calcium content of mitochondria from brain sub regions following short-term forebrain ischemia and recirculation in the rat. J. Neurochem. 63 (1994) 1812-1819
46. Zaheer M., Weber P.A., Smith J.R., Cornerford M.L., and Ellott G.F. Role of inducible nitric oxide synthase in pharmacological preconditioning with monophosphoryl lipid A. J. Mol. Cell. Cardiol. 29 (1997) 1567-1576