T3 replacement does not prevent excitotoxic cell death but reduces developmental neuronal apoptosis in newborn mice

European Journal of Paediatric Neurology

Volumn 11, Issue 3, 2007, Pages 129-135

  Sárközy, Gergely ^a,b   Griesmaier, Elke ^a   He, Xiangying ^a,c   Kapelari, Klaus ^a   Urbanek, Martina ^a   Simbruner, Georg ^a   Gressens, Pierre ^d   Keller, Matthias ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b SEMMELWEIS UNIVERSITY   (Hungary)

^c ZHENGZHOU UNIVERSITY   (China)

^d HÔPITAL ROBERT DEBRÉ   (France)

Author keywords

Brain injury; Excitotoxicity; Newborn; T3

Indexed keywords

IBOTENIC ACID; LIOTHYRONINE; THYROID HORMONE; THYROXINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN DAMAGE; CELL COUNT; CELL DEATH; CONTROLLED STUDY; ENCEPHALOMALACIA; EXCITOTOXICITY; GRAY MATTER; HORMONE SUBSTITUTION; LIOTHYRONINE BLOOD LEVEL; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RIGHT HEMISPHERE; THYROXINE BLOOD LEVEL; WHITE MATTER;

ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; CASPASE 3; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION ROUTES; EXCITATORY AMINO ACID AGONISTS; FUNCTIONAL LATERALITY; IBOTENIC ACID; MICE; NEURONS; NEUROTOXICITY SYNDROMES; TIME FACTORS; TRIIODOTHYRONINE;

EID: 34247227619     PISSN: 10903798     EISSN: 15322130     Source Type: Journal    
DOI: 10.1016/j.ejpn.2006.11.009     Document Type: Article

References (29)

1. Kilbride H.W., Thorstad K., and Daily D.K. Preschool outcome of less than 801-gram preterm infants compared with full-term siblings. Pediatrics 113 (2004) 742-747
2. Linnet K.M., Wisborg K., Agerbo E., Secher N.J., Thomsen P.H., and Henriksen T.B. Gestational age, birthweight and the risk of hyperkinetic disorder 1172. Arch Dis Child (2006)
3. Dammann O., and Leviton A. Inflammatory brain damage in preterm newborns-dry numbers, wet lab, and causal inferences 7238. Early Hum Dev 79 (2004) 1-15
4. Kadhim H., Khalifa M., Deltenre P., Casimir G., and Sebire G. Molecular mechanisms of cell death in periventricular leukomalacia. Neurology 67 (2006) 293-299
5. Haynes R.L., Baud O., Li J., Kinney H.C., Volpe J.J., and Folkerth D.R. Oxidative and nitrative injury in periventricular leukomalacia: a review 5 178. Brain Pathol 15 (2005) 225-233
6. Loeliger M., Watson C.S., Reynolds J.D., Penning D.H., Harding R., Bocking A.D., et al. Extracellular glutamate levels and neuropathology in cerebral white matter following repeated umbilical cord occlusion in the near term fetal sheep 1. Neuroscience 116 (2003) 705-714
7. Marret S., Mukendi R., Gadisseux J.F., Gressens P., and Evrard P. Effect of ibotenate on brain development: an excitotoxic mouse model of microgyria and posthypoxic-like lesions. J Neuropathol Exp Neurol 54 (1995) 358-370
8. Volpe J.J. Neurobiology of periventricular leukomalacia in the premature infant. Pediatr Res 50 (2001) 553-562
9. O'Shea T.M. Cerebral palsy in very preterm infants: new epidemiological insights 12. Ment Retard Dev Disabil Res Rev 8 (2002) 135-145
10. Zupan V., Nehlig A., Evrard P., and Gressens P. Prenatal blockade of vasoactive intestinal peptide alters cell death and synaptic equipment in the murine neocortex. Pediatr Res 47 (2000) 53-63
11. Lucas A., Morley R., and Fewtrell M.S. Low triiodothyronine concentration in preterm infants and subsequent intelligence quotient (IQ) at 8 year follow up. BMJ 312 (1996) 1132-1133
12. den Ouden A.L., Kok J.H., Verkerk P.H., Brand R., and Verloove-Vanhorick S.P. The relation between neonatal thyroxine levels and neurodevelopmental outcome at age 5 and 9 years in a national cohort of very preterm and/or very low birth weight infants. Pediatr Res 39 (1996) 142-145
13. Reuss M.L., Paneth N., Pinto-Martin J.A., Lorenz J.M., and Susser M. The relation of transient hypothyroxinemia in preterm infants to neurologic development at two years of age. N Engl J Med 334 (1996) 821-827
14. Paul D.A., Leef K.H., Stefano J.L., and Bartoshesky L. Thyroid function in very-low-birth-weight infants with intraventricular hemorrhage. Clin Pediatr (Philadelphia) 39 (2000) 651-656
15. Paul D.A., Leef K.H., Voss B., Stefano J.L., and Bartoshesky L. Thyroxine and illness severity in very low-birth-weight infants. Thyroid 11 (2001) 871-875
16. Leviton A., Paneth N., Reuss M.L., Susser M., Allred E.N., Dammann O., et al. Hypothyroxinemia of prematurity and the risk of cerebral white matter damage. J Pediatr 134 (1999) 706-711
17. van Wassenaer A.G., Kok J.H., Briet J.M., Pijning A.M., and de Vijlder J.J. Thyroid function in very preterm newborns: possible implications. Thyroid 9 (1999) 85-91
18. Oden J., and Freemark M. Thyroxine supplementation in preterm infants: critical analysis. Curr Opin Pediatr 14 (2002) 447-452
19. van Wassenaer A.G., and Kok J.H. Hypothyroxinaemia and thyroid function after preterm birth. Semin Neonatol 9 (2004) 3-11
20. Giordano G., Aimaretti G., and Ghigo E. Variations of pituitary function over time after brain injuries: the lesson from a prospective study 1. Pituitary 8 (2005) 227-231
21. Keller M., Simbruner G., Gorna A., Urbanek M., Tinhofer I., Griesmaier E., et al. Systemic application of granulocyte-colony stimulating factor and stem cell factor exacerbates excitotoxic brain injury in newborn mice. Pediatr Res 59 (2006) 549-553
22. Keller M., Yang J., Griesmaier E., Gorna A., Sarkozy G., Urbanek M., et al. Erythropoietin is neuroprotective against NMDA-receptor-mediated excitotoxic brain injury in newborn mice. Neurobiol Dis (2006)
23. D'Alecy L.G. Thyroid hormone in neural rescue 1. Thyroid 7 (1997) 115-124
24. Shibusawa N., Hashimoto K., Nikrodhanond A.A., Liberman M.C., Applebury M.L., Liao X.H., et al. Thyroid hormone action in the absence of thyroid hormone receptor DNA-binding in vivo 11. J Clin Invest 112 (2003) 588-597
25. Weiss R.E., Xu J., Ning G., Pohlenz J., O'Malley B.W., and Refetoff S. Mice deficient in the steroid receptor co-activator 1 (SRC-1) are resistant to thyroid hormone. EMBO J 18 (1999) 1900-1904
26. Maia A.L., Kieffer J.D., Harney J.W., and Larsen P.R. Effect of 3,5,3′-Triiodothyronine (T3) administration on dio1 gene expression and T3 metabolism in normal and type 1 deiodinase-deficient mice. Endocrinology 136 (1995) 4842-4849
27. Palha J.A., Nissanov J., Fernandes R., Sousa J.C., Bertrand L., Dratman M.B., et al. Thyroid hormone distribution in the mouse brain: the role of transthyretin. Neuroscience 113 (2002) 837-847
28. Buss R.R., and Oppenheim R.W. Role of programmed cell death in normal neuronal development and function. Anat Sci Int 79 (2004) 191-197
29. van Wassenaer A.G., Westera J., Houtzager B.A., and Kok J.H. Ten-year follow-up of children born at <30 weeks' gestational age supplemented with thyroxine in the neonatal period in a randomized, controlled trial. Pediatrics 116 (2005) e613-e618