Targeted exome sequencing in clear cell renal cell carcinoma tumors suggests aberrant chromatin regulation as a crucial step in ccRCC development

Human Mutation

Volumn 33, Issue 7, 2012, Pages 1059-1062

  Duns, Gerben ^a   Hofstra, Robert M W ^a   Sietzema, Jantine G ^a   Hollema, Harry ^a   van Duivenbode, Inge ^a   Kuik, Angela ^a   Giezen, Cor ^a   Jan, Osinga ^a   Bergsma, Jelkje J ^a   Bijnen, Harrie ^a   van der Vlies, Pieter ^a   van den Berg, Eva ^a   Kok, Klaas ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

BAP1; CcRCC; Chromatin remodeling; Chromosome 3; PBRM1; SETD2; Tumor suppressor

Indexed keywords

BAF180 PROTEIN; BRCA1 ASSOCIATED RING DOMAIN PROTEIN 1; NUCLEAR PROTEIN; UNCLASSIFIED DRUG; VON HIPPEL LINDAU PROTEIN;

ARTICLE; BAP1 GENE; CANCER CELL CULTURE; CARCINOGENESIS; CHROMATIN; COMPLEX FORMATION; EXOME; GENE INACTIVATION; GENE MUTATION; GENE SEQUENCE; GENETIC CODE; GENETIC SCREENING; HISTONE UBIQUITINATION; KIDNEY CARCINOMA; NUCLEOTIDE SEQUENCE; PBRM1 GENE; PRIMARY TUMOR; PRIORITY JOURNAL; TUMOR GENE;

CARCINOMA, RENAL CELL; CHROMATIN; CHROMOSOMES, HUMAN, PAIR 3; EXOME; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; NUCLEAR PROTEINS; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN THIOLESTERASE;

EID: 84861898073     PISSN: 10597794     EISSN: 10981004     Source Type: Journal    
DOI: 10.1002/humu.22090     Document Type: Article

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