-
1
-
-
0032742992
-
The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus
-
Weyer C, Bogardus C, Mott DM, Pratley RE. The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. J Clin Invest 1999; 104(6): 787-794.
-
(1999)
J Clin Invest
, vol.104
, Issue.6
, pp. 787-794
-
-
Weyer, C.1
Bogardus, C.2
Mott, D.M.3
Pratley, R.E.4
-
2
-
-
0037283601
-
The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes
-
Kahn SE. The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes. Diabetologia 2003; 46(1): 3-19.
-
(2003)
Diabetologia
, vol.46
, Issue.1
, pp. 3-19
-
-
Kahn, S.E.1
-
3
-
-
0043026915
-
Beta-cell apoptosis in the pathogenesis of human type 2 diabetes mellitus
-
Leonardi O, Mints G, Hussain MA. Beta-cell apoptosis in the pathogenesis of human type 2 diabetes mellitus. Eur J Endocrinol 2003; 149(2): 99-102.
-
(2003)
Eur J Endocrinol
, vol.149
, Issue.2
, pp. 99-102
-
-
Leonardi, O.1
Mints, G.2
Hussain, M.A.3
-
4
-
-
31444445097
-
Increased expression of cyclooxygenase-2 in human pancreatic islets treated with high glucose or ligands of the advanced glycation endproduct-specific receptor (AGER), and in islets from diabetic mice
-
Shanmugam N, Todorov I, Nair I, Omori K, Reddy M, Natarajan R. Increased expression of cyclooxygenase-2 in human pancreatic islets treated with high glucose or ligands of the advanced glycation endproduct-specific receptor (AGER), and in islets from diabetic mice. Diabetologia 2006; 49(1): 100-107.
-
(2006)
Diabetologia
, vol.49
, Issue.1
, pp. 100-107
-
-
Shanmugam, N.1
Todorov, I.2
Nair, I.3
Omori, K.4
Reddy, M.5
Natarajan, R.6
-
5
-
-
0030456403
-
Reducing sugars trigger oxidative modification and apoptosis in pancreatic beta-cells by provoking oxidative stress through the glycation reaction
-
Kaneto H, Fujii J, Myint T, et al. Reducing sugars trigger oxidative modification and apoptosis in pancreatic beta-cells by provoking oxidative stress through the glycation reaction. Biochem J 1996; 320(Pt 3): 855-863.
-
(1996)
Biochem J
, vol.320
, Issue.PART 3
, pp. 855-863
-
-
Kaneto, H.1
Fujii, J.2
Myint, T.3
-
6
-
-
57749184079
-
Induction of apoptosis of Beta cells of the pancreas by advanced glycation end-products, important mediators of chronic complications of diabetes mellitus
-
Lim M, Park L, Shin G, Hong H, Kang I, Park Y. Induction of apoptosis of Beta cells of the pancreas by advanced glycation end-products, important mediators of chronic complications of diabetes mellitus. Ann N Y Acad Sci 2008; 1150: 311-315.
-
(2008)
Ann N Y Acad Sci
, vol.1150
, pp. 311-315
-
-
Lim, M.1
Park, L.2
Shin, G.3
Hong, H.4
Kang, I.5
Park, Y.6
-
7
-
-
79955134104
-
AGEs decrease insulin synthesis in pancreatic β-cell by repressing Pdx-1 protein expression at the post-translational level
-
Shu T, Zhu Y, Wang H, Lin Y, Ma Z, Han X. AGEs decrease insulin synthesis in pancreatic β-cell by repressing Pdx-1 protein expression at the post-translational level. PLoS One 2011; 6(4): e18782.
-
(2011)
PLoS One
, vol.6
, Issue.4
-
-
Shu, T.1
Zhu, Y.2
Wang, H.3
Lin, Y.4
Ma, Z.5
Han, X.6
-
8
-
-
66649125230
-
Advanced glycation end products inhibit glucose-stimulated insulin secretion through nitric oxide-dependent inhibition of cytochrome c oxidase and adenosine triphosphate synthesis
-
Zhao Z, Zhao C, Zhang XH, et al. Advanced glycation end products inhibit glucose-stimulated insulin secretion through nitric oxide-dependent inhibition of cytochrome c oxidase and adenosine triphosphate synthesis. Endocrinology 2009; 150(6): 2569-2576.
-
(2009)
Endocrinology
, vol.150
, Issue.6
, pp. 2569-2576
-
-
Zhao, Z.1
Zhao, C.2
Zhang, X.H.3
-
9
-
-
80052590678
-
Advanced glycation end products downregulate glucokinase in mice
-
Jung H, Joo J, Jeon Y, et al. Advanced glycation end products downregulate glucokinase in mice. Diabetes Metab Res Rev 2011; 27(6): 557-563.
-
(2011)
Diabetes Metab Res Rev
, vol.27
, Issue.6
, pp. 557-563
-
-
Jung, H.1
Joo, J.2
Jeon, Y.3
-
10
-
-
0036167208
-
Diabetes and advanced glycation endproducts
-
Vlassara H, Palace MR. Diabetes and advanced glycation endproducts. J Intern Med 2002; 251(2): 87-101.
-
(2002)
J Intern Med
, vol.251
, Issue.2
, pp. 87-101
-
-
Vlassara, H.1
Palace, M.R.2
-
12
-
-
0028951461
-
Mechanism of autoxidative glycosylation: identification of glyoxal and arabinose as intermediates in the autoxidative modification of proteins by glucose
-
Wells-Knecht KJ, Zyzak DV, Litchfield JE, Thorpe SR, Baynes JW. Mechanism of autoxidative glycosylation: identification of glyoxal and arabinose as intermediates in the autoxidative modification of proteins by glucose. Biochemistry 1995; 34(11): 3702-3709.
-
(1995)
Biochemistry
, vol.34
, Issue.11
, pp. 3702-3709
-
-
Wells-Knecht, K.J.1
Zyzak, D.V.2
Litchfield, J.E.3
Thorpe, S.R.4
Baynes, J.W.5
-
13
-
-
0025298551
-
The glyoxalase system: new developments towards functional characterization of a metabolic pathway fundamental to biological life
-
Thornalley PJ. The glyoxalase system: new developments towards functional characterization of a metabolic pathway fundamental to biological life. Biochem J 1990; 269(1): 1-11.
-
(1990)
Biochem J
, vol.269
, Issue.1
, pp. 1-11
-
-
Thornalley, P.J.1
-
14
-
-
34250160687
-
RAGE on the Toll Road?
-
Lin L. RAGE on the Toll Road? Cell Mol Immunol 2006; 3(5): 351-358.
-
(2006)
Cell Mol Immunol
, vol.3
, Issue.5
, pp. 351-358
-
-
Lin, L.1
-
15
-
-
33746427544
-
Diabetes and advanced glycoxidation end products
-
Huebschmann A, Regensteiner J, Vlassara H, Reusch J. Diabetes and advanced glycoxidation end products. Diabetes Care 2006; 29(6): 1420-1432.
-
(2006)
Diabetes Care
, vol.29
, Issue.6
, pp. 1420-1432
-
-
Huebschmann, A.1
Regensteiner, J.2
Vlassara, H.3
Reusch, J.4
-
16
-
-
0035153678
-
Advanced glycation end products, their receptors and diabetic angiopathy
-
Wautier JL, Guillausseau PJ. Advanced glycation end products, their receptors and diabetic angiopathy. Diabetes Metab 2001; 27(5 Pt 1): 535-542.
-
(2001)
Diabetes Metab
, vol.27
, Issue.5 PART 1
, pp. 535-542
-
-
Wautier, J.L.1
Guillausseau, P.J.2
-
17
-
-
0033615356
-
N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression
-
Kislinger T, Fu C, Huber B, et al. N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression. J Biol Chem 1999; 274(44): 31740-31749.
-
(1999)
J Biol Chem
, vol.274
, Issue.44
, pp. 31740-31749
-
-
Kislinger, T.1
Fu, C.2
Huber, B.3
-
18
-
-
34247209253
-
Nox1-based NADPH oxidase-derived superoxide is required for VSMC activation by advanced glycation end-products
-
San Martin A, Foncea R, Laurindo FR, Ebensperger R, Griendling KK, Leighton F. Nox1-based NADPH oxidase-derived superoxide is required for VSMC activation by advanced glycation end-products. Free Radic Biol Med 2007; 42(11): 1671-1679.
-
(2007)
Free Radic Biol Med
, vol.42
, Issue.11
, pp. 1671-1679
-
-
San Martin, A.1
Foncea, R.2
Laurindo, F.R.3
Ebensperger, R.4
Griendling, K.K.5
Leighton, F.6
-
19
-
-
0034996659
-
Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE
-
Wautier M, Chappey O, Corda S, Stern D, Schmidt A, Wautier J. Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE. Am J Physiol Endocrinol Metab 2001; 280(5): E685-694.
-
(2001)
Am J Physiol Endocrinol Metab
, vol.280
, Issue.5
-
-
Wautier, M.1
Chappey, O.2
Corda, S.3
Stern, D.4
Schmidt, A.5
Wautier, J.6
-
20
-
-
29244467696
-
Aminoguanidine and metformin prevent the reduced rate of HDL-mediated cell cholesterol efflux induced by formation of advanced glycation end products
-
Machado AP, Pinto RS, Moysés ZP, Nakandakare ER, Quintão EC, Passarelli M. Aminoguanidine and metformin prevent the reduced rate of HDL-mediated cell cholesterol efflux induced by formation of advanced glycation end products. Int J Biochem Cell Biol 2006; 38(3): 392-403.
-
(2006)
Int J Biochem Cell Biol
, vol.38
, Issue.3
, pp. 392-403
-
-
Machado, A.P.1
Pinto, R.S.2
Moysés, Z.P.3
Nakandakare, E.R.4
Quintão, E.C.5
Passarelli, M.6
-
21
-
-
0030612749
-
JC-1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis
-
Salvioli S, Ardizzoni A, Franceschi C, Cossarizza A. JC-1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis. FEBS Lett 1997; 411(1): 77-82.
-
(1997)
FEBS Lett
, vol.411
, Issue.1
, pp. 77-82
-
-
Salvioli, S.1
Ardizzoni, A.2
Franceschi, C.3
Cossarizza, A.4
-
22
-
-
78751634252
-
Caffeic acid phenethyl ester triggers apoptosis through induction of loss of mitochondrial membrane potential in CCRF-CEM cells
-
Avci{dotless} CB, Gündüz C, Baran Y, et al. Caffeic acid phenethyl ester triggers apoptosis through induction of loss of mitochondrial membrane potential in CCRF-CEM cells. J Cancer Res Clin Oncol 2011; 137(1): 41-47.
-
(2011)
J Cancer Res Clin Oncol
, vol.137
, Issue.1
, pp. 41-47
-
-
Avci, C.B.1
Gündüz, C.2
Baran, Y.3
-
23
-
-
33750505407
-
CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation
-
Bardag-Gorce F, French BA, Nan L, et al. CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation. Exp Mol Pathol 2006; 81(3): 191-201.
-
(2006)
Exp Mol Pathol
, vol.81
, Issue.3
, pp. 191-201
-
-
Bardag-Gorce, F.1
French, B.A.2
Nan, L.3
-
24
-
-
53449089230
-
Antioxidant SOD mimetic prevents NADPH oxidase-induced oxidative stress and renal damage in the early stage of experimental diabetes and hypertension
-
Peixoto EB, Pessoa BS, Biswas SK, Lopes de Faria JB. Antioxidant SOD mimetic prevents NADPH oxidase-induced oxidative stress and renal damage in the early stage of experimental diabetes and hypertension. Am J Nephrol 2009; 29(4): 309-318.
-
(2009)
Am J Nephrol
, vol.29
, Issue.4
, pp. 309-318
-
-
Peixoto, E.B.1
Pessoa, B.S.2
Biswas, S.K.3
Lopes de Faria, J.B.4
-
25
-
-
0023372410
-
A new technique for highly sensitive detection of superoxide dismutase activity by chemiluminescence
-
Corbisier P, Houbion A, Remacle J. A new technique for highly sensitive detection of superoxide dismutase activity by chemiluminescence. Anal Biochem 1987; 164(1): 240-247.
-
(1987)
Anal Biochem
, vol.164
, Issue.1
, pp. 240-247
-
-
Corbisier, P.1
Houbion, A.2
Remacle, J.3
-
26
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248-254.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
27
-
-
84859207907
-
Off-target thiol alkylation by the NADPH oxidase inhibitor 3-benzyl-7-(2-benzoxazolyl)thio-1,2,3-triazolo[4,5-d]pyrimidine (VAS2870)
-
Sun QA, Hess DT, Wang B, Miyagi M, Stamler JS. Off-target thiol alkylation by the NADPH oxidase inhibitor 3-benzyl-7-(2-benzoxazolyl)thio-1, 2, 3-triazolo[4, 5-d]pyrimidine (VAS2870). Free Radic Biol Med 2012; 52(9): 1897-1902.
-
(2012)
Free Radic Biol Med
, vol.52
, Issue.9
, pp. 1897-1902
-
-
Sun, Q.A.1
Hess, D.T.2
Wang, B.3
Miyagi, M.4
Stamler, J.S.5
-
28
-
-
33745189788
-
Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation
-
ten Freyhaus H, Huntgeburth M, Wingler K, et al. Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation. Cardiovasc Res 2006; 71(2): 331-341.
-
(2006)
Cardiovasc Res
, vol.71
, Issue.2
, pp. 331-341
-
-
ten Freyhaus, H.1
Huntgeburth, M.2
Wingler, K.3
-
29
-
-
17344392308
-
A new mathematical model for relative quantification in real-time RT-PCR
-
Pfaffl M. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001; 29(9): e45.
-
(2001)
Nucleic Acids Res
, vol.29
, Issue.9
-
-
Pfaffl, M.1
-
30
-
-
0028673970
-
Bcl-2 gene family and the regulation of programmed cell death
-
Yin X, Oltvai Z, Veis-Novack D, Linette G, Korsmeyer S. Bcl-2 gene family and the regulation of programmed cell death. Cold Spring Harb Symp Quant Biol 1994; 59: 387-393.
-
(1994)
Cold Spring Harb Symp Quant Biol
, vol.59
, pp. 387-393
-
-
Yin, X.1
Oltvai, Z.2
Veis-Novack, D.3
Linette, G.4
Korsmeyer, S.5
-
31
-
-
26444478269
-
Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation
-
Ramasamy R, Vannucci S, Yan S, Herold K, Yan S, Schmidt A. Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation. Glycobiology 2005; 15(7): 16R-28R.
-
(2005)
Glycobiology
, vol.15
, Issue.7
-
-
Ramasamy, R.1
Vannucci, S.2
Yan, S.3
Herold, K.4
Yan, S.5
Schmidt, A.6
-
32
-
-
78650890745
-
Inhibition of the receptor for advanced glycation endproducts (RAGE) protects pancreatic β-cells
-
Zhu Y, Shu T, Lin Y, et al. Inhibition of the receptor for advanced glycation endproducts (RAGE) protects pancreatic β-cells. Biochem Biophys Res Commun 2011; 404(1): 159-165.
-
(2011)
Biochem Biophys Res Commun
, vol.404
, Issue.1
, pp. 159-165
-
-
Zhu, Y.1
Shu, T.2
Lin, Y.3
-
33
-
-
48249085391
-
Oxidative stress as a major culprit in kidney disease in diabetes
-
Forbes JM, Coughlan MT, Cooper ME. Oxidative stress as a major culprit in kidney disease in diabetes. Diabetes 2008; 57(6): 1446-1454.
-
(2008)
Diabetes
, vol.57
, Issue.6
, pp. 1446-1454
-
-
Forbes, J.M.1
Coughlan, M.T.2
Cooper, M.E.3
-
34
-
-
84863513527
-
Advanced glycation end-products induce injury to pancreatic beta cells through oxidative stress
-
Lin N, Zhang H, Su Q. Advanced glycation end-products induce injury to pancreatic beta cells through oxidative stress. Diabetes Metab 2012; 38(3): 250-257.
-
(2012)
Diabetes Metab
, vol.38
, Issue.3
, pp. 250-257
-
-
Lin, N.1
Zhang, H.2
Su, Q.3
-
35
-
-
78649965893
-
RAGE ligands induce apoptotic cell death of pancreatic β-cells via oxidative stress
-
Lee BW, Chae HY, Kwon SJ, Park SY, Ihm J, Ihm SH. RAGE ligands induce apoptotic cell death of pancreatic β-cells via oxidative stress. Int J Mol Med 2010; 26(6): 813-818.
-
(2010)
Int J Mol Med
, vol.26
, Issue.6
, pp. 813-818
-
-
Lee, B.W.1
Chae, H.Y.2
Kwon, S.J.3
Park, S.Y.4
Ihm, J.5
Ihm, S.H.6
|