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Volumn 41, Issue 9, 2013, Pages 4949-4962

Phosphorylation of the alternative mRNA splicing factor 45 (SPF45) by Clk1 regulates its splice site utilization, cell migration and invasion

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 1 LIKE KINASE 1; FAS ANTIGEN; FIBRONECTIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEASOME; REGULATOR PROTEIN; SERINE; SPLICING FACTOR 45; UNCLASSIFIED DRUG;

EID: 84877287737     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt170     Document Type: Article
Times cited : (53)

References (55)
  • 1
    • 56749098074 scopus 로고    scopus 로고
    • Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
    • Pan, Q., Shai, O., Lee, L.J., Frey, B.J. and Blencowe, B.J. (2008) Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing. Nat. Genet., 40, 1413-1415.
    • (2008) Nat. Genet. , vol.40 , pp. 1413-1415
    • Pan, Q.1    Shai, O.2    Lee, L.J.3    Frey, B.J.4    Blencowe, B.J.5
  • 2
    • 34548758543 scopus 로고    scopus 로고
    • Splicing in disease: Disruption of the splicing code and the decoding machinery
    • Wang, G.S. and Cooper, T.A. (2007) Splicing in disease: disruption of the splicing code and the decoding machinery. Nat. Rev. Genet., 8, 749-761.
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 749-761
    • Wang, G.S.1    Cooper, T.A.2
  • 3
    • 18344364099 scopus 로고    scopus 로고
    • Understanding alternative splicing: Towards a cellular code
    • Matlin, A.J., Clark, F. and Smith, C.W. (2005) Understanding alternative splicing: towards a cellular code. Nat. Rev. Mol. Cell Biol., 6, 386-398.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 386-398
    • Matlin, A.J.1    Clark, F.2    Smith, C.W.3
  • 4
    • 34447106755 scopus 로고    scopus 로고
    • Alternative splicing in cancer: Noise, functional, or systematic?
    • Skotheim, R.I. and Nees, M. (2007) Alternative splicing in cancer: noise, functional, or systematic? Int. J. Biochem. Cell Biol., 39, 1432-1449.
    • (2007) Int. J. Biochem. Cell Biol. , vol.39 , pp. 1432-1449
    • Skotheim, R.I.1    Nees, M.2
  • 5
    • 68549111145 scopus 로고    scopus 로고
    • The spliceosome: A self-organized macromolecular machine in the nucleus?
    • Rino, J. and Carmo-Fonseca, M. (2009) The spliceosome: a self-organized macromolecular machine in the nucleus? Trends Cell Biol., 19, 375-384.
    • (2009) Trends Cell Biol. , vol.19 , pp. 375-384
    • Rino, J.1    Carmo-Fonseca, M.2
  • 6
    • 0026543785 scopus 로고
    • Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2
    • Mayeda, A. and Krainer, A.R. (1992) Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2. Cell, 68, 365-375.
    • (1992) Cell , vol.68 , pp. 365-375
    • Mayeda, A.1    Krainer, A.R.2
  • 7
    • 0033565285 scopus 로고    scopus 로고
    • HnRNP A/B proteins are required for inhibition of HIV-1 pre-mRNA splicing
    • Caputi, M., Mayeda, A., Krainer, A.R. and Zahler, A.M. (1999) hnRNP A/B proteins are required for inhibition of HIV-1 pre-mRNA splicing. EMBO J., 18, 4060-4067.
    • (1999) EMBO J. , vol.18 , pp. 4060-4067
    • Caputi, M.1    Mayeda, A.2    Krainer, A.R.3    Zahler, A.M.4
  • 8
    • 23844471326 scopus 로고    scopus 로고
    • HnRNP L represses exon splicing via a regulated exonic splicing silencer
    • Rothrock, C.R., House, A.E. and Lynch, K.W. (2005) HnRNP L represses exon splicing via a regulated exonic splicing silencer. EMBO J., 24, 2792-2802.
    • (2005) EMBO J. , vol.24 , pp. 2792-2802
    • Rothrock, C.R.1    House, A.E.2    Lynch, K.W.3
  • 9
    • 4644256654 scopus 로고    scopus 로고
    • HnRNP A1 and the SR proteins ASF/SF2 and SC35 have antagonistic functions in splicing of beta-tropomyosin exon 6B
    • Expert-Bezancon, A., Sureau, A., Durosay, P., Salesse, R., Groeneveld, H., Lecaer, J.P. and Marie, J. (2004) hnRNP A1 and the SR proteins ASF/SF2 and SC35 have antagonistic functions in splicing of beta-tropomyosin exon 6B. J. Biol. Chem., 279, 38249-38259.
    • (2004) J. Biol. Chem. , vol.279 , pp. 38249-38259
    • Expert-Bezancon, A.1    Sureau, A.2    Durosay, P.3    Salesse, R.4    Groeneveld, H.5    Lecaer, J.P.6    Marie, J.7
  • 11
    • 0344074646 scopus 로고    scopus 로고
    • Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors
    • Hanamura, A., Caceres, J.F., Mayeda, A., Franza, B.R. Jr and Krainer, A.R. (1998) Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors. RNA, 4, 430-444.
    • (1998) RNA , vol.4 , pp. 430-444
    • Hanamura, A.1    Caceres, J.F.2    Mayeda, A.3    Franza Jr., B.R.4    Krainer, A.R.5
  • 12
    • 55549143293 scopus 로고    scopus 로고
    • The emerging role of splicing factors in cancer
    • Grosso, A.R., Martins, S. and Carmo-Fonseca, M. (2008) The emerging role of splicing factors in cancer. EMBO Rep., 9, 1087-1093.
    • (2008) EMBO Rep. , vol.9 , pp. 1087-1093
    • Grosso, A.R.1    Martins, S.2    Carmo-Fonseca, M.3
  • 15
    • 38349085591 scopus 로고    scopus 로고
    • Regulation of alternative splicing by reversible protein phosphorylation
    • Stamm, S. (2008) Regulation of alternative splicing by reversible protein phosphorylation. J. Biol. Chem., 283, 1223-1227.
    • (2008) J. Biol. Chem. , vol.283 , pp. 1223-1227
    • Stamm, S.1
  • 16
    • 0031042396 scopus 로고    scopus 로고
    • Phosphorylation of the ASF/SF2 RS domain affects both protein-protein and protein-RNA interactions and is necessary for splicing
    • Xiao, S.H. and Manley, J.L. (1997) Phosphorylation of the ASF/SF2 RS domain affects both protein-protein and protein-RNA interactions and is necessary for splicing. Genes Dev., 11, 334-344.
    • (1997) Genes Dev. , vol.11 , pp. 334-344
    • Xiao, S.H.1    Manley, J.L.2
  • 17
    • 1142310938 scopus 로고    scopus 로고
    • Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock
    • Shin, C., Feng, Y. and Manley, J.L. (2004) Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock. Nature, 427, 553-558.
    • (2004) Nature , vol.427 , pp. 553-558
    • Shin, C.1    Feng, Y.2    Manley, J.L.3
  • 18
    • 77957754590 scopus 로고    scopus 로고
    • Mechanism of dephosphorylation of the SR protein ASF/SF2 by protein phosphatase 1
    • Ma, C.T., Ghosh, G., Fu, X.D. and Adams, J.A. (2010) Mechanism of dephosphorylation of the SR protein ASF/SF2 by protein phosphatase 1. J. Mol. Biol., 403, 386-404.
    • (2010) J. Mol. Biol. , vol.403 , pp. 386-404
    • Ma, C.T.1    Ghosh, G.2    Fu, X.D.3    Adams, J.A.4
  • 19
    • 0030863326 scopus 로고    scopus 로고
    • In vivo regulation of alternative pre-mRNA splicing by the Clk1 protein kinase
    • Duncan, P.I., Stojdl, D.F., Marius, R.M. and Bell, J.C. (1997) In vivo regulation of alternative pre-mRNA splicing by the Clk1 protein kinase. Mol. Cell. Biol., 17, 5996-6001.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 5996-6001
    • Duncan, P.I.1    Stojdl, D.F.2    Marius, R.M.3    Bell, J.C.4
  • 20
    • 0032526770 scopus 로고    scopus 로고
    • The Clk2 and Clk3 dual-specificity protein kinases regulate the intranuclear distribution of SR proteins and influence pre-mRNA splicing
    • Duncan, P.I., Stojdl, D.F., Marius, R.M., Scheit, K.H. and Bell, J.C. (1998) The Clk2 and Clk3 dual-specificity protein kinases regulate the intranuclear distribution of SR proteins and influence pre-mRNA splicing. Exp. Cell Res., 241, 300-308.
    • (1998) Exp. Cell Res. , vol.241 , pp. 300-308
    • Duncan, P.I.1    Stojdl, D.F.2    Marius, R.M.3    Scheit, K.H.4    Bell, J.C.5
  • 21
    • 84863992155 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase phosphorylation of splicing factor 45 (SPF45) regulates SPF45 alternative splicing site utilization, proliferation, and cell adhesion
    • Al-Ayoubi, A.M., Zheng, H., Liu, Y., Bai, T. and Eblen, S.T. (2012) Mitogen-activated protein kinase phosphorylation of splicing factor 45 (SPF45) regulates SPF45 alternative splicing site utilization, proliferation, and cell adhesion. Mol. Cell. Biol., 32, 2880-2893.
    • (2012) Mol. Cell. Biol. , vol.32 , pp. 2880-2893
    • Al-Ayoubi, A.M.1    Zheng, H.2    Liu, Y.3    Bai, T.4    Eblen, S.T.5
  • 22
    • 0030028882 scopus 로고    scopus 로고
    • The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution
    • Colwill, K., Pawson, T., Andrews, B., Prasad, J., Manley, J.L., Bell, J.C. and Duncan, P.I. (1996) The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution. EMBO J., 15, 265-275.
    • (1996) EMBO J. , vol.15 , pp. 265-275
    • Colwill, K.1    Pawson, T.2    Andrews, B.3    Prasad, J.4    Manley, J.L.5    Bell, J.C.6    Duncan, P.I.7
  • 23
    • 0032547829 scopus 로고    scopus 로고
    • Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivo
    • Misteli, T., Caceres, J.F., Clement, J.Q., Krainer, A.R., Wilkinson, M.F. and Spector, D.L. (1998) Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivo. J. Cell Biol., 143, 297-307.
    • (1998) J. Cell Biol. , vol.143 , pp. 297-307
    • Misteli, T.1    Caceres, J.F.2    Clement, J.Q.3    Krainer, A.R.4    Wilkinson, M.F.5    Spector, D.L.6
  • 24
    • 39749151729 scopus 로고    scopus 로고
    • Combination of Clk family kinase and SRp75 modulates alternative splicing of Adenovirus E1A
    • Yomoda, J., Muraki, M., Kataoka, N., Hosoya, T., Suzuki, M., Hagiwara, M. and Kimura, H. (2008) Combination of Clk family kinase and SRp75 modulates alternative splicing of Adenovirus E1A. Genes Cells, 13, 233-244.
    • (2008) Genes Cells , vol.13 , pp. 233-244
    • Yomoda, J.1    Muraki, M.2    Kataoka, N.3    Hosoya, T.4    Suzuki, M.5    Hagiwara, M.6    Kimura, H.7
  • 25
    • 0026731973 scopus 로고
    • Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing
    • Mermoud, J.E., Cohen, P. and Lamond, A.I. (1992) Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing. Nucleic Acids Res., 20, 5263-5269.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 5263-5269
    • Mermoud, J.E.1    Cohen, P.2    Lamond, A.I.3
  • 26
    • 0026702493 scopus 로고
    • Adenosine phosphorothioates (ATP alpha S and ATP tau S) differentially affect the two steps of mammalian pre-mRNA splicing
    • Tazi, J., Daugeron, M.C., Cathala, G., Brunel, C. and Jeanteur, P. (1992) Adenosine phosphorothioates (ATP alpha S and ATP tau S) differentially affect the two steps of mammalian pre-mRNA splicing. J. Biol. Chem., 267, 4322-4326.
    • (1992) J. Biol. Chem. , vol.267 , pp. 4322-4326
    • Tazi, J.1    Daugeron, M.C.2    Cathala, G.3    Brunel, C.4    Jeanteur, P.5
  • 27
    • 0031468240 scopus 로고    scopus 로고
    • Both phosphorylation and dephosphorylation of ASF/SF2 are required for pre-mRNA splicing in vitro
    • Cao, W., Jamison, S.F. and Garcia-Blanco, M.A. (1997) Both phosphorylation and dephosphorylation of ASF/SF2 are required for pre-mRNA splicing in vitro. RNA, 3, 1456-1467.
    • (1997) RNA , vol.3 , pp. 1456-1467
    • Cao, W.1    Jamison, S.F.2    Garcia-Blanco, M.A.3
  • 28
    • 0031711073 scopus 로고    scopus 로고
    • Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex
    • Neubauer, G., King, A., Rappsilber, J., Calvio, C., Watson, M., Ajuh, P., Sleeman, J., Lamond, A. and Mann, M. (1998) Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. Nat. Genet., 20, 46-50.
    • (1998) Nat. Genet. , vol.20 , pp. 46-50
    • Neubauer, G.1    King, A.2    Rappsilber, J.3    Calvio, C.4    Watson, M.5    Ajuh, P.6    Sleeman, J.7    Lamond, A.8    Mann, M.9
  • 29
    • 0033200012 scopus 로고    scopus 로고
    • G-patch: A new conserved domain in eukaryotic RNA-processing proteins and type D retroviral polyproteins
    • Aravind, L. and Koonin, E.V. (1999) G-patch: a new conserved domain in eukaryotic RNA-processing proteins and type D retroviral polyproteins. Trends Biochem. Sci., 24, 342-344.
    • (1999) Trends Biochem. Sci. , vol.24 , pp. 342-344
    • Aravind, L.1    Koonin, E.V.2
  • 30
    • 8644284892 scopus 로고    scopus 로고
    • Interaction between a G-patch protein and a spliceosomal DEXD/H-box ATPase that is critical for splicing
    • Silverman, E.J., Maeda, A., Wei, J., Smith, P., Beggs, J.D. and Lin, R.J. (2004) Interaction between a G-patch protein and a spliceosomal DEXD/H-box ATPase that is critical for splicing. Mol. Cell. Biol., 24, 10101-10110.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 10101-10110
    • Silverman, E.J.1    Maeda, A.2    Wei, J.3    Smith, P.4    Beggs, J.D.5    Lin, R.J.6
  • 32
    • 4944256316 scopus 로고    scopus 로고
    • Proteinases of betaretroviruses bind single-stranded nucleic acids through a novel interaction module, the G-patch
    • Svec, M., Bauerova, H., Pichova, I., Konvalinka, J. and Strisovsky, K. (2004) Proteinases of betaretroviruses bind single-stranded nucleic acids through a novel interaction module, the G-patch. FEBS Lett., 576, 271-276.
    • (2004) FEBS Lett. , vol.576 , pp. 271-276
    • Svec, M.1    Bauerova, H.2    Pichova, I.3    Konvalinka, J.4    Strisovsky, K.5
  • 35
    • 0142182109 scopus 로고    scopus 로고
    • Human SPF45, a splicing factor, has limited expression in normal tissues, is overexpressed in many tumors, and can confer a multidrug-resistant phenotype to cells
    • Sampath, J., Long, P.R., Shepard, R.L., Xia, X., Devanarayan, V., Sandusky, G.E., Perry, W.L. 3rd, Dantzig, A.H., Williamson, M., Rolfe, M. et al. (2003) Human SPF45, a splicing factor, has limited expression in normal tissues, is overexpressed in many tumors, and can confer a multidrug-resistant phenotype to cells. Am. J. Pathol., 163, 1781-1790.
    • (2003) Am. J. Pathol. , vol.163 , pp. 1781-1790
    • Sampath, J.1    Long, P.R.2    Shepard, R.L.3    Xia, X.4    Devanarayan, V.5    Sandusky, G.E.6    Perry III, W.L.7    Dantzig, A.H.8    Williamson, M.9    Rolfe, M.10
  • 36
    • 23044441609 scopus 로고    scopus 로고
    • Human splicing factor SPF45 (RBM17) confers broad multidrug resistance to anticancer drugs when overexpressed - A phenotype partially reversed by selective estrogen receptor modulators
    • Perry, W.L. 3rd, Shepard, R.L., Sampath, J., Yaden, B., Chin, W.W., Iversen, P.W., Jin, S., Lesoon, A., O'Brien, K.A., Peek, V.L. et al. (2005) Human splicing factor SPF45 (RBM17) confers broad multidrug resistance to anticancer drugs when overexpressed-a phenotype partially reversed by selective estrogen receptor modulators. Cancer Res., 65, 6593-6600.
    • (2005) Cancer Res. , vol.65 , pp. 6593-6600
    • Perry III, W.L.1    Shepard, R.L.2    Sampath, J.3    Yaden, B.4    Chin, W.W.5    Iversen, P.W.6    Jin, S.7    Lesoon, A.8    O'Brien, K.A.9    Peek, V.L.10
  • 37
    • 0034747719 scopus 로고    scopus 로고
    • Biochemical and biological functions of the N-terminal, noncatalytic domain of extracellular signal-regulated kinase 2
    • Eblen, S.T., Catling, A.D., Assanah, M.C. and Weber, M.J. (2001) Biochemical and biological functions of the N-terminal, noncatalytic domain of extracellular signal-regulated kinase 2. Mol. Cell. Biol., 21, 249-259.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 249-259
    • Eblen, S.T.1    Catling, A.D.2    Assanah, M.C.3    Weber, M.J.4
  • 38
    • 0025940103 scopus 로고
    • Identification and characterization of a novel cytoskeleton-associated pp60src substrate
    • Wu, H., Reynolds, A.B., Kanner, S.B., Vines, R.R. and Parsons, J.T. (1991) Identification and characterization of a novel cytoskeleton-associated pp60src substrate. Mol. Cell. Biol., 11, 5113-5124.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5113-5124
    • Wu, H.1    Reynolds, A.B.2    Kanner, S.B.3    Vines, R.R.4    Parsons, J.T.5
  • 39
    • 78649696631 scopus 로고    scopus 로고
    • Cortactin phosphorylated by ERK1/2 localizes to sites of dynamic actin regulation and is required for carcinoma lamellipodia persistence
    • Kelley, L.C., Hayes, K.E., Ammer, A.G., Martin, K.H. and Weed, S.A. (2010) Cortactin phosphorylated by ERK1/2 localizes to sites of dynamic actin regulation and is required for carcinoma lamellipodia persistence. PLoS One, 5, e13847.
    • (2010) PLoS One , vol.5
    • Kelley, L.C.1    Hayes, K.E.2    Ammer, A.G.3    Martin, K.H.4    Weed, S.A.5
  • 40
    • 80052741232 scopus 로고    scopus 로고
    • Caspase-mediated cleavage of RNA-binding protein HuR regulates c-Myc protein expression after hypoxic stress
    • Talwar, S., Jin, J., Carroll, B., Liu, A., Gillespie, M.B. and Palanisamy, V. (2011) Caspase-mediated cleavage of RNA-binding protein HuR regulates c-Myc protein expression after hypoxic stress. J. Biol. Chem., 286, 32333-32343.
    • (2011) J. Biol. Chem. , vol.286 , pp. 32333-32343
    • Talwar, S.1    Jin, J.2    Carroll, B.3    Liu, A.4    Gillespie, M.B.5    Palanisamy, V.6
  • 42
    • 0037013146 scopus 로고    scopus 로고
    • Splicing regulation at the second catalytic step by Sex-lethal involves 3' splice site recognition by SPF45
    • Lallena, M.J., Chalmers, K.J., Llamazares, S., Lamond, A.I. and Valcarcel, J. (2002) Splicing regulation at the second catalytic step by Sex-lethal involves 3' splice site recognition by SPF45. Cell, 109, 285-296.
    • (2002) Cell , vol.109 , pp. 285-296
    • Lallena, M.J.1    Chalmers, K.J.2    Llamazares, S.3    Lamond, A.I.4    Valcarcel, J.5
  • 43
    • 84857693787 scopus 로고    scopus 로고
    • Fibronectin induces endothelial cell migration through beta1 integrin and Src-dependent phosphorylation of fibroblast growth factor receptor-1 at tyrosines 653/654 and 766
    • Zou, L., Cao, S., Kang, N., Huebert, R.C. and Shah, V.H. (2012) Fibronectin induces endothelial cell migration through beta1 integrin and Src-dependent phosphorylation of fibroblast growth factor receptor-1 at tyrosines 653/654 and 766. J. Biol. Chem., 287, 7190-7202.
    • (2012) J. Biol. Chem. , vol.287 , pp. 7190-7202
    • Zou, L.1    Cao, S.2    Kang, N.3    Huebert, R.C.4    Shah, V.H.5
  • 44
    • 79953220086 scopus 로고    scopus 로고
    • Ligand-independent activation of c-Met by fibronectin and alpha(5)beta(1)-integrin regulates ovarian cancer invasion and metastasis
    • Mitra, A.K., Sawada, K., Tiwari, P., Mui, K., Gwin, K. and Lengyel, E. (2011) Ligand-independent activation of c-Met by fibronectin and alpha(5)beta(1)-integrin regulates ovarian cancer invasion and metastasis. Oncogene, 30, 1566-1576.
    • (2011) Oncogene , vol.30 , pp. 1566-1576
    • Mitra, A.K.1    Sawada, K.2    Tiwari, P.3    Mui, K.4    Gwin, K.5    Lengyel, E.6
  • 46
    • 0021085369 scopus 로고
    • Fibronectin promotes epithelial migration of cultured rabbit cornea in situ
    • Nishida, T., Nakagawa, S., Awata, T., Ohashi, Y., Watanabe, K. and Manabe, R. (1983) Fibronectin promotes epithelial migration of cultured rabbit cornea in situ. J. Cell Biol., 97, 1653-1657.
    • (1983) J. Cell Biol. , vol.97 , pp. 1653-1657
    • Nishida, T.1    Nakagawa, S.2    Awata, T.3    Ohashi, Y.4    Watanabe, K.5    Manabe, R.6
  • 47
    • 79952328998 scopus 로고    scopus 로고
    • Cortactin: A multifunctional regulator of cellular invasiveness
    • Kirkbride, K.C., Sung, B.H., Sinha, S. and Weaver, A.M. (2011) Cortactin: a multifunctional regulator of cellular invasiveness. Cell Adh. Migr., 5, 187-198.
    • (2011) Cell Adh. Migr. , vol.5 , pp. 187-198
    • Kirkbride, K.C.1    Sung, B.H.2    Sinha, S.3    Weaver, A.M.4
  • 49
    • 0032697492 scopus 로고    scopus 로고
    • Signaling pathways and structural domains required for phosphorylation of EMS1/cortactin
    • Campbell, D.H., Sutherland, R.L. and Daly, R.J. (1999) Signaling pathways and structural domains required for phosphorylation of EMS1/cortactin. Cancer Res., 59, 5376-5385.
    • (1999) Cancer Res. , vol.59 , pp. 5376-5385
    • Campbell, D.H.1    Sutherland, R.L.2    Daly, R.J.3
  • 50
    • 2942594602 scopus 로고    scopus 로고
    • Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP
    • Martinez-Quiles, N., Ho, H.Y., Kirschner, M.W., Ramesh, N. and Geha, R.S. (2004) Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP. Mol. Cell. Biol., 24, 5269-5280.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 5269-5280
    • Martinez-Quiles, N.1    Ho, H.Y.2    Kirschner, M.W.3    Ramesh, N.4    Geha, R.S.5
  • 51
    • 0029744344 scopus 로고    scopus 로고
    • SRPK1 and Clk/Sty protein kinases show distinct substrate specificities for serine/arginine-rich splicing factors
    • Colwill, K., Feng, L.L., Yeakley, J.M., Gish, G.D., Caceres, J.F., Pawson, T. and Fu, X.D. (1996) SRPK1 and Clk/Sty protein kinases show distinct substrate specificities for serine/arginine-rich splicing factors. J. Biol. Chem., 271, 24569-24575.
    • (1996) J. Biol. Chem. , vol.271 , pp. 24569-24575
    • Colwill, K.1    Feng, L.L.2    Yeakley, J.M.3    Gish, G.D.4    Caceres, J.F.5    Pawson, T.6    Fu, X.D.7
  • 52
    • 0033785992 scopus 로고    scopus 로고
    • Biochemical characterization and localization of the dual specificity kinase CLK1
    • Menegay, H.J., Myers, M.P., Moeslein, F.M. and Landreth, G.E. (2000) Biochemical characterization and localization of the dual specificity kinase CLK1. J. Cell Sci., 113(Pt.18), 3241-3253.
    • (2000) J. Cell Sci. , vol.113 , Issue.PART 18 , pp. 3241-3253
    • Menegay, H.J.1    Myers, M.P.2    Moeslein, F.M.3    Landreth, G.E.4
  • 53
    • 0037451327 scopus 로고    scopus 로고
    • A novel splicing regulator shares a nuclear import pathway with SR proteins
    • Lai, M.C., Kuo, H.W., Chang, W.C. and Tarn, W.Y. (2003) A novel splicing regulator shares a nuclear import pathway with SR proteins. EMBO J., 22, 1359-1369.
    • (2003) EMBO J. , vol.22 , pp. 1359-1369
    • Lai, M.C.1    Kuo, H.W.2    Chang, W.C.3    Tarn, W.Y.4
  • 54
    • 3042836378 scopus 로고    scopus 로고
    • A molecular link between SR protein dephosphorylation and mRNA export
    • Huang, Y., Yario, T.A. and Steitz, J.A. (2004) A molecular link between SR protein dephosphorylation and mRNA export. Proc. Natl Acad. Sci. USA, 101, 9666-9670.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 9666-9670
    • Huang, Y.1    Yario, T.A.2    Steitz, J.A.3
  • 55
    • 84863084923 scopus 로고    scopus 로고
    • Cortactin in cell migration and cancer at a glance
    • MacGrath, S.M. and Koleske, A.J. (2012) Cortactin in cell migration and cancer at a glance. J. Cell Sci., 125, 1621-1626.
    • (2012) J. Cell Sci. , vol.125 , pp. 1621-1626
    • MacGrath, S.M.1    Koleske, A.J.2


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