Elevation of brain magnesium prevents and reverses cognitive deficits and synaptic loss in Alzheimer's disease mouse model

Journal of Neuroscience

Volumn 33, Issue 19, 2013, Pages 8423-8441

  Li, Wei ^a   Yu, Jia ^b   Liu, Yong ^c   Huang, Xiaojie ^a   Abumaria, Nashat ^a   Zhu, Ying ^a   Huang, Xian ^a   Xiong, Wenxiang ^a   Ren, Chi ^a   Liu, Xian Guo ^c   Chui, Dehua ^b   Liu, Guosong ^a,d  

^a Tsinghua University ^*  (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c SUN YAT SEN UNIVERSITY   (China)

^d UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN [1-40]; AMYLOID BETA PROTEIN [1-42]; BETA SECRETASE; CALCINEURIN; CALPAIN; CYCLIN DEPENDENT KINASE 5; INSULIN RECEPTOR SUBSTRATE 1; MAGNESIUM; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; COGNITIVE DEFECT; CONTROLLED STUDY; DOWN REGULATION; ELECTROSTIMULATION; FEMALE; FLAME PHOTOMETRY; FLUID INTAKE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MEMORY DISORDER; MOUSE; NERVE CELL PLASTICITY; NERVE DEGENERATION; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RECOGNITION; SIGNAL TRANSDUCTION; SYNAPSE; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANALYSIS OF VARIANCE; ANIMALS; BODY WEIGHT; BRAIN; BUTYRATES; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; EXPLORATORY BEHAVIOR; GLUTAMATE DECARBOXYLASE; HUMANS; MAGNESIUM; MALE; MAZE LEARNING; MICE; MICE, TRANSGENIC; MICROSCOPY, ELECTRON, TRANSMISSION; MUTATION; NEURONS; NEUROPROTECTIVE AGENTS; PATCH-CLAMP TECHNIQUES; PEPTIDE FRAGMENTS; PRESENILIN-1; PRESYNAPTIC TERMINALS; REACTION TIME; SYNAPSES; TISSUE DISTRIBUTION; VESICULAR ACETYLCHOLINE TRANSPORT PROTEINS;

EID: 84877281990     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4610-12.2013     Document Type: Article

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