Preventive effects of monascus on androgen-related diseases: Androgenetic alopecia, benign prostatic hyperplasia, and prostate cancer

Journal of Agricultural and Food Chemistry

Volumn 61, Issue 18, 2013, Pages 4379-4386

  Chiu, Hui Wen ^a   Chen, Mei Huei ^b   Fang, Wen Hung ^a   Hung, Ching Ming ^a   Chen, Yen Lin ^b   Wu, Ming Der ^b   Yuan, Gwo Fang ^b   Wu, Ming Jiuan ^c   Wang, Ying Jan ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b FOOD INDUSTRY RESEARCH AND DEVELOPMENT INSTITUTE   (Taiwan)

^c CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

Author keywords

androgenetic alopecia; benign prostate hyperplasia; Monascus; prostate cancer

Indexed keywords

ANDROGENETIC ALOPECIA; BENIGN PROSTATE HYPERPLASIA; BENIGN PROSTATIC HYPERPLASIA; DIHYDROTESTOSTERONE; MONASCUS; PROSTATE CANCERS; PROTECTIVE EFFECTS; TUMOR VOLUMES;

DRUG INTERACTIONS; TUMORS; UROLOGY;

DISEASES;

ANDROSTANOLONE; METHYLNITROSOUREA; PROSTATE SPECIFIC ANTIGEN; TESTOSTERONE;

AGING; ALOPECIA; ANIMAL; ARTICLE; BLOOD; C57BL MOUSE; CBA MOUSE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; MALE; METABOLISM; MONASCUS; MOUSE; ORAL DRUG ADMINISTRATION; PHYSIOLOGY; PROSTATE; PROSTATE HYPERTROPHY; PROSTATE TUMOR; RAT; SPRAGUE DAWLEY RAT;

ADMINISTRATION, ORAL; AGING; ALOPECIA; ANIMALS; DIHYDROTESTOSTERONE; MALE; METHYLNITROSOUREA; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MONASCUS; PROSTATE; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC HYPERPLASIA; PROSTATIC NEOPLASMS; RATS; RATS, SPRAGUE-DAWLEY; TESTOSTERONE;

EID: 84877267450     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf400873w     Document Type: Article

References (35)

1. Ma, J.; Li, Y.; Ye, Q.; Li, J.; Hua, Y.; Ju, D.; Zhang, D.; Cooper, R.; Chang, M. Constituents of red yeast rice, a traditional Chinese food and medicine J. Agric. Food Chem. 2000, 48, 5220-5225
2. Chen, X. P. Research status on prescriptions for 52 diseases J. Tradit. Med. 1987, 5, 61-63
3. Hsu, W. H.; Pan, T. M. Monascus purpureus-fermented products and oral cancer: a review Appl. Microbiol. Biotechnol. 2012, 93, 1831-1842
4. Lee, C. L.; Wang, J. J.; Pan, T. M. Red mold rice extract represses amyloid beta peptide-induced neurotoxicity via potent synergism of anti-inflammatory and antioxidative effect Appl. Microbiol. Biotechnol. 2008, 79, 829-841
5. Wang, T. H.; Lin, T. F. Monascus rice products Adv. Food Nutr. Res. 2007, 53, 123-159
6. Chen, R. J.; Hung, C. M.; Chen, Y. L.; Wu, M. D.; Yuan, G. F.; Wang, Y. J. Monascuspiloin induces apoptosis and autophagic cell death in human prostate cancer cells via the Akt and AMPK signaling pathways J. Agric. Food Chem. 2012, 60, 7185-7193
7. Chiu, H. W.; Fang, W. H.; Chen, Y. L.; Wu, M. D.; Yuan, G. F.; Ho, S. Y.; Wang, Y. J. Monascuspiloin enhances the radiation sensitivity of human prostate cancer cells by stimulating endoplasmic reticulum stress and inducing autophagy PLoS One 2012, 7, e40462
8. Hong, M. Y.; Henning, S.; Moro, A.; Seeram, N. P.; Zhang, Y.; Heber, D. Chinese red yeast rice inhibition of prostate tumor growth in SCID mice Cancer Prev. Res. (Phila.) 2011, 4, 608-615
9. Arias-Santiago, S.; Arrabal-Polo, M. A.; Buendia-Eisman, A.; Arrabal-Martin, M.; Gutierrez-Salmeron, M. T.; Giron-Prieto, M. S.; Jimenez-Pacheco, A.; Calonje, J. E.; Naranjo-Sintes, R.; Zuluaga-Gomez, A.; Serrano Ortega, S. Androgenetic alopecia as an early marker of benign prostatic hyperplasia J.Am. Acad. Dermatol. 2012, 66, 401-408
10. McElwee, K. J.; Shapiro, J. S. Promising therapies for treating and/or preventing androgenic alopecia Skin Ther. Lett. 2012, 17, 1-4
11. Kaufman, K. D. Androgens and alopecia Mol. Cell. Endocrinol. 2002, 198, 89-95
12. Oh, B. R.; Kim, S. J.; Moon, J. D.; Kim, H. N.; Kwon, D. D.; Won, Y. H.; Ryu, S. B.; Park, Y. I. Association of benign prostatic hyperplasia with male pattern baldness Urology 1998, 51, 744-748
13. Price, V. H. Treatment of hair loss N. Engl. J. Med. 1999, 341, 964-973
14. Kaufman, K. D.; Olsen, E. A.; Whiting, D.; Savin, R.; DeVillez, R.; Bergfeld, W.; Price, V. H.; Van Neste, D.; Roberts, J. L.; Hordinsky, M.; Shapiro, J.; Binkowitz, B.; Gormley, G. J. Finasteride in the treatment of men with androgenetic alopecia. Finasteride Male Pattern Hair Loss Study Group J. Am. Acad. Dermatol. 1998, 39, 578-589
15. Trueb, R. M. Molecular mechanisms of androgenetic alopecia Exp. Gerontol. 2002, 37, 981-990
16. Nicholson, T. M.; Ricke, W. A. Androgens and estrogens in benign prostatic hyperplasia: past, present and future Differentiation 2011, 82, 184-199
17. Tammela, T. L. Endocrine prevention and treatment of prostate cancer Mol. Cell. Endocrinol. 2012, 360, 59-67
18. Li, S. H.; Ryu, J. H.; Park, S. E.; Cho, Y. S.; Park, J. W.; Lee, W. J.; Chun, Y. S. Vitamin C SUPPL.ementation prevents testosterone-induced hyperplasia of rat prostate by down-regulating HIF-1α J. Nutr. Biochem. 2010, 21, 801-808
19. Tiwari, A.; Krishna, N. S.; Nanda, K.; Chugh, A. Benign prostatic hyperplasia: an insight into current investigational medical therapies Expert. Opin. Invest. Drugs 2005, 14, 1359-1372
20. Attard, G.; Sarker, D.; Reid, A.; Molife, R.; Parker, C.; de Bono, J. S. Improving the outcome of patients with castration-resistant prostate cancer through rational drug development Br. J. Cancer 2006, 95, 767-774
21. Pisters, L. L. The challenge of locally advanced prostate cancer Semin. Oncol. 1999, 26, 202-216
22. Sundberg, J. P.; King, L. E.; Bascom, C. Animal models for male pattern (androgenetic) alopecia Eur. J. Dermatol. 2001, 11, 321-325
23. Narayanan, B. A.; Reddy, B. S.; Bosland, M. C.; Nargi, D.; Horton, L.; Randolph, C.; Narayanan, N. K. Exisulind in combination with celecoxib modulates epidermal growth factor receptor, cyclooxygenase-2, and cyclin D1 against prostate carcinogenesis: in vivo evidence Clin. Cancer Res. 2007, 13, 5965-5973
24. Peng, P. L.; Kuo, W. H.; Tseng, H. C.; Chou, F. P. Synergistic tumor-killing effect of radiation and berberine combined treatment in lung cancer: the contribution of autophagic cell death Int. J. Radiat. Oncol. Biol. Phys. 2008, 70, 529-542
25. Catalona, W. J.; Smith, D. S.; Wolfert, R. L.; Wang, T. J.; Rittenhouse, H. G.; Ratliff, T. L.; Nadler, R. B. Evaluation of percentage of free serum prostate-specific antigen to improve specificity of prostate cancer screening JAMA, J. Am. Med. Assoc.. 1995, 274, 1214-1220
26. McCormick, D. L.; Rao, K. V.; Steele, V. E.; Lubet, R. A.; Kelloff, G. J.; Bosland, M. C. Chemoprevention of rat prostate carcinogenesis by 9- cis -retinoic acid Cancer Res. 1999, 59, 521-524
27. Prosperi, E. Multiple roles of the proliferating cell nuclear antigen: DNA replication, repair and cell cycle control Prog. Cell Cycle Res. 1997, 3, 193-210
28. Whiting, D. A. Male pattern hair loss: current understanding Int. J. Dermatol. 1998, 37, 561-566
29. Ellis, J. A.; Sinclair, R. D. Male pattern baldness: current treatments, future prospects Drug Discov. Today 2008, 13, 791-797
30. Kumar, N.; Rungseevijitprapa, W.; Narkkhong, N. A.; Suttajit, M.; Chaiyasut, C. 5α-Reductase inhibition and hair growth promotion of some Thai plants traditionally used for hair treatment J. Ethnopharmacol. 2012, 139, 765-771
31. Nahata, A.; Dixit, V. K. Sphaeranthus indicus attenuates testosterone induced prostatic hypertrophy in albino rats Phytother. Res. 2011, 25, 1839-1848
32. Miller, J.; Tarter, T. H. Combination therapy with dutasteride and tamsulosin for the treatment of symptomatic enlarged prostate Clin. Interv. Aging 2009, 4, 251-258
33. Azzouni, F.; Mohler, J. Role of 5α-reductase inhibitors in prostate cancer prevention and treatment Urology 2012, 79, 1197-1205
34. Hong, M. Y.; Seeram, N. P.; Zhang, Y.; Heber, D. Chinese red yeast rice versus lovastatin effects on prostate cancer cells with and without androgen receptor overexpression J. Med. Food 2008, 11, 657-666
35. Lachenmeier, D. W.; Monakhova, Y. B.; Kuballa, T.; Lobell-Behrends, S.; Maixner, S.; Kohl-Himmelseher, M.; Waldner, A.; Steffen, C. NMR evaluation of total statin content and HMG-CoA reductase inhibition in red yeast rice (Monascus spp.) food SUPPL.ements Chin. Med. 2012, 7, 8