Animal models for male pattern (androgenetic) alopecia

European Journal of Dermatology

Volumn 11, Issue 4, 2001, Pages 321-325

  Sundberg, J P ^a   King, L E ^a   Bascom, C ^a  

^a JACKSON LABORATORY   (United States)

Author keywords

Androchronogenetic alopecia mouse; Macaca arctoides; Nude mice; Pattern baldness; Severe combined immunodeficient mice; Skin grafts; Testosterone conditioned nude mice

Indexed keywords

TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; HORMONE ACTION; MALE TYPE ALOPECIA; NONHUMAN; PATHOPHYSIOLOGY; RAT; REVIEW; SKIN GRAFT; XENOGRAFT;

ALOPECIA; ANIMALS; CRICETINAE; DISEASE MODELS, ANIMAL; HUMANS; MACACA; MALE; MICE;

EID: 0034943736     PISSN: 11671122     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (66)

1. The "hairless" gene in mouse and man
2. Comparison of alopecia areata in human and nonhuman mammalian species
3. A male pattern baldness in wattled starlings resembling the condition in man
4. Androgenetic alopecia: In vivo models
5. Noninflammatory reactions of the pilosebaceous unit and disorders of the hair shaft
6. The inheritance of common baldness: Two B or not to B?
7. Male hormone stimulation is prerequisite and an incitant in common baldness
8. Geometric relationships between the matrix of the hair bulb and its dermal papilla in normal and alopecic scalp
9. Hair growth and hair regeneration
10. The anatomy of the human scalp
11. Biochemical and trichological characterization of diffuse a opecia in women
12. The importance of adequate serum ferritin levels during oral cyproterone acetate and ethinyl oestradiol treatment of diffuse androgen-dependent alopecia in women
13. Hair problems in women
14. Anagen hairs may fail to replace telogen hairs in early androgenetic female alopecia
15. Aging and hair cycles
16. Periodicity in the growth and shedding of hair
17. Considerazioni sulla filogenesi del cuoio capelluto
18. The phylogeny of baldness
19. Baldness in nonhuman primates
20. Baldness of the red uakari (Cacajao rubicundus): Histological properties and enzyme activities of hair follicles
21. Nonhuman primate model of baldness: Premature aging of hair follicle and hormones
22. The histopathology of hair loss
23. The effect of N,N-diethyl-4-methyl-3-oxo-4-aza-5 alpha-androstane-17 beta-carboxamine, a 5 alpha-recluctase inhibitor and antiandrogen, on the development of baldness in the stumptailed macaque
24. Inhibition of hair growth by testosterone in the presence of dermal papilla cells from the frontal bald scalp of the postpuberal stumptailed macaque
25. Morphological and biochemical studies on hair follicles in common baldness of stumptailed macaque (Macaca speciosa)
26. Studies of common baldness of the stumptailed macaque: 1. Distribution of the hair follicles
27. Reinnervation of hair follicle end organs and Meissner corpuscles in skin graft of macaques
28. Action of topical minoxidil in the bald stump-tailed macaque
29. Chemical agents and peptides affect hair growth
30. The effects of topical diazoxide on hair follicular growth and physiology of the stumptailed macaque
31. Macaque and rodent models for the screening of drugs for stimulating hair growth
32. Effects of hypertrichotic agents on follicular and nonfollicular cells in vitro
33. Papular atrichia resulting from mutations in the rhesus macaque (Macaca mulatta) hairless gene
34. Androgen-induced delay of hair growth in the golden Syrian hamster
35. Mouse mutations as animal models and biomedical tools for dermatological research
36. Skin and its appendages: Normal anatomy and pathology of spontaneous, transgenic and targeted mouse mutations
37. Mouse models for the study of human hair loss
38. The effect of testosterone, cyproterone acetate, and minoxidil on hair loss in the androchronogenetic alopecia mouse
39. Animal models of androgen-dependent disorders of the pilosebaceous apparatus. 1. The androchrono-genetic alopecia (AGA) mouse as a model for male-pattern baldness
40. The in vitro transformation of testosterone and the ability of its 5α-reduced, 16B-hydroxylated metabolites to induce hair loss in the andro-chronogenetic alopecia (AGA) mouse
41. Melanocyte and gonad activity as potential modifying factors in C3H/HeJ mouse alopecia areata
42. Maintenance of skin xenografts of widely divergent phylogenetic origin on congenitally athymic (nude) mice
43. Tumorgenicity of green turtle fibropapilloma-derived fibroblast lines in immunodeficient mice
44. Hair growth in scalp grafts from patients with alopecia areata ana alopecia universalis grafted onto nude mice
45. Alopecia areata is a T-lymphocyte mediated autoimmune disease: Lesional human T-lymphocytes transfer alopecia areata to human skin grafts on SCID mice
46. Modulation of epidermal growth factor receptors in psoriatic lesions during treatment with topical EGF
47. Long-term maintenance of psoriatic human skin on congenitally athymic (nude) mice
48. Nude mouse-human skin graft model III. Studies on generalized psoriasis
49. Transplantation of psoriatic skin on to nude athymic mice does not maintain features of psoriasis
50. Is epidermal cell proliferation in psoriatic skin grafts on nude mice driven by T-cell derived cytokines?
51. Severe combined immunodeficiency mouse and human psoriatic skin chimeras. Validation of a new animal model
52. A morphological study on normal and balding scalp follicles grafted onto nude mice
53. The use of scalp grafts onto nude mice as a model for human hair growth: Is there something new for hair growth drug screening programs?
54. Reduced linear hair growth rates of vellus and of terminal hairs produced by human balding scalp grafted onto nude mice
55. Long-term maintenance of normal human skin on congenitally athymic (nude) mice
56. Development of human fetal skin transplanted to the nude mouse
57. Nude mice are not hairless. A morphologic study